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Group A-beta Hemolytic Streptococci에 의한 소아 인두편도염에 있어서 Cefdinir의 항균력과 임상적 및 세균학적 효과에 관한 연구
정지영,신선희,안영민,안병문,신영규,배영민,박수은,김종국,이종국,마상혁,장진근,차성호,Chung, Ji-Young,Sin, Seon-Hee,Ahn, Young-Min,Ahn, Byung-Moon,Sin, Young-Gyu,Bae, Young-Min,Park, Soo-Eun,Kim, Jong-Guk,Lee, Jong-Guk,Ma, Saung-Hyuk,Chan 대한소아감염학회 2003 Pediatric Infection and Vaccine Vol.10 No.1
최근 국내 erythromycin 내성률이 증가하는 추세임을 보고하였고 erythromycin의 경우 내성의 증가는 항생제 사용량의 증가와 일치하고 있음을 보고하였다. 그래서 macrolide에 의한 내성균주의 확산을 막고 임상에서 보고되는 penicillin에 의한 치료 실패를 줄이기 위해 A군 연쇄구균 치료에 제일차 약물로 cephalosporin을 고려할 수 있다. Cefdinir의 A군 연쇄구균에 대한 항균력과 인두 편도염에 대한 우수한 임상효과 및 높은 안전성을 미루어 볼 때, Cefdinir는 A군 연쇄구균에 의한 소아 인두 편도염에 유효한 항생제로 사용될 수 있다. Objective : To determine the clinical and bacteriologic efficacy and safety of Cefdinir in acute pharyngitis and pharyngotonsillitis caused by group A beta hemolytic streptococci in pediatric patients. Methods : Children aged 3 through 12 years who visited the hospitals enrolled in this study with signs and symptoms of pharyngitis or pharyngotonsillitis since May to December 2002, were taken throat culture and given Cefdinir(12 mg/kg/day, in three divided doses) for 7 days. Two hundred thirty five patients were enrolled and 90 patients who showed positive culture results were followed up for the signs and symptoms during the treatment to determine clinical efficacy. Follow-up culture were done at the end of the study and bacteriologic efficacy was determined Results : Ninety out of 235 patients who visited the hospitals with the signs and symptoms of pharyngitis showed positive growth on throat culture. Seventy nine patients were clinically and microbiologically assessable. The bacteriologic eradication rates of S. pyogenes were 100% in all the children treated with Cefdinir. Clinical cure rates were not different between less than 7 days-treated group(75%) and just 7 days-treated group(98.6%)(P=0.077). Two patients reported adverse reaction during Cefdinir treatment. Antimicrobial sensitivity of Cefdinir against S. pyogenes was 100% with range of MIC being less than 0.5 ${\mu}g/mL$. Conclusion : It seems that Cefdinir is one of reliable and well-tolerated drugs for the treatment of group A beta hemolytic streptococcal pharyngotonsillitis in children. It needs to be investigated short term efficacy in terms of improving drug compliance and impact of economic point of view. We can recognized that still high rate of the erythromycin resistant group A streptococci in our community should be monitored every year.
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보행보조차를 사용할 때와 유모차를 보행보조도구로 사용할 때의 보행 안정성 비교
박민수(Min Su Park),조승현(Seung Hyun Cho),신선희(Seon Hee Shin),김유신(Yu Sin Kim),이승진(Seung Jin Lee),손승희(Seung Hee Son),박수희(Soo Hee Park),양영애(Young Ae Yang) 대한인간공학회 2009 대한인간공학회 학술대회논문집 Vol.2009 No.11
The purpose of this study is to find the problems of stability when people use the bassinet as an ambulatory aid for old people. Structural analysis of an outdoor rollator and a bassinet is used to check the stability of both tools. And we analyze and discover the differences of the body segment's angle and the distance from pressure cone apex to greater trochanter. This study was investigated from may 16th, 2008 to november 5th, 2008. The 13 adults who are the members of I university in Gyeongsangnam-do, Korea and don't have disorders of musculoskeletal system volunteered to participate in this study. According to structural analysis of the both tool, we compared the structural stability of the outdoor rollator with the structural stability of the bassinet. And when the participants walked using both tool, the motions are captured and analysed. The participants walked each 1 time using the outdoor rollator and the bassinet as ambulatory aid. We measured the angle of shoulder joint, trunk's angle from the ground when the participants were walking. And we found the distance from participants' pressure cone apex and greater trochanter. We analyzed the data which is collected in SPSS 15.0 use. We use a technical statistics to analyze the general quality and the result were analyzed with use of a paired sample T-test. The significance level was controlled with 0.05. Following the structural analysis, the bassinet has the lower structural stability than the outdoor rollator. And according to the gait analysis, result of shoulder angle when people use the both tools, had significant difference (p=0.002). However, the angles between ground and trunk when people use both tools, didn't have significance (p>0.05). nd the result to compare the distances from the pressure cone apex to the greater trochanter when people use the rollator with when people use the bassinet, had significant difference (p=0.000). When the people used the bassinet as ambulatory aid, the angle of the shoulder joint was bigger than to use the outdoor rollator. The angle of trunk was not a difference between to use the outdoor rollator and the bassinet. And distance from pressure cone apex to greater trochanter was far to use the bassinet than to use the outdoor rollator. Therefore, through the structure analysis and gait analysis of the bassinet and the outdoor rollator, we can be aware of that the bassinet has problem of stability and when a person uses the bassinet as an ambulatory aid, especially supporting body weight, can be occurred the problems of stability.
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