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申敏亨(신민형) 관훈클럽 2002 관훈저널 Vol.43 No.4

Biobehavioral Pain Profile을 이용한 구강안면동통 환자의 행동양식에 관한 연구

신민,Shin, Min 대한안면통증구강내과학회 1998 Journal of Oral Medicine and Pain Vol.23 No.4

The aim of this study was to measure effects of the following items to pain and pain behavior reaction in patients with chronic orofacial pain. Items that contribute to the first factor(Environmental Influences) measure environmental sources of information that may affect illness behavior; Second factro(Loss of Control) measure appraisals and attributions perceived to influence personal views aobut pain; Third factor(Health Care Avoidance) measures a variety of avoidant behaviors; Fouth factor(Past and Current Experiences) measures experiences with treatment); Fifth factor(Physiological Responsivity) measures physiological parameters that are experienced in association with pain; Sixth factor(Thoughts of Disease Progression) measures thoughts regarding the etiology and progression of disease in relation to pain. 150 patients that were consist of 40 male and 110 female were participated in this study. The obtained results of this study were as follows : 1. Environmental influences and loss of control scales were recorded high score in patients with chronic orofacial pain 2. "Physician's descriptions of what your pain will be like" and "Physician's facial expression when they ask about your pain" items from the environmental influences were recorded high score. These results indicated that responsibility of doctro is very important to the pain reaction behavior of patients. Also, items from thoughts regarding the etiology and progression of disease in relation to pain influenced to the pain reaction. 3. There were significant defferences on the "nurses' descriptions of what you pain will be like", "physician's and nurses' facial expression when they ask about your pain", "TV and radio", and "Literature" items from the environmental influences between male and female patients. 4. There were no significant differences on the each scale between arthrogenous and combitnation group and significant correlated with all 6 scales.

Ramos B세포의 아포토시스 과정에서 이상 발현되는 Zinc Finger 유전자의 규명

신민선,김수영,동승명,나은영,이석형,박원상,이정용,유남진,신민선 대한병리학회 1998 Journal of Pathology and Translational Medicine Vol.32 No.12

지구 저궤도에서의 궤도파편 분포 및 진화모델을 이용한 궤도파편 환경 예측 연구

신민,김영록,이재은,박상영,최규홍,김응현,김규선 한국우주과학회 2006 한국우주과학회보 Vol.15 No.2

구강내 백색병소와 편평상피세포암종에서 bcl-2와 NOS₂ 비교발현에 관한 연구

신민,김은철,Shin, Min,Kim, Eun-Cheol 대한안면통증구강내과학회 1999 Journal of Oral Medicine and Pain Vol.24 No.2

The proto-oncogene bcl-2 confers a survival advantage to cells by blocking programmed cell death (apoptosis). Overexpression of bcl-2 probably plays a role in tumorigenesis, and the expression of the bcl-2 protein has been investigated in many kinds of tumors. An increased expression of nitric oxide synthetase(NOS) has been observed in human colon cancer cell lines as well as in human gynecological, breast, and CNS tumors. However there have been only a few reports on the expression of bcl-2 and $NOS_2$ in oral white lesions and cancer. The aim of this study was to investigate the relationship between the expression of Bcl-2 and $NOS_2$ and several pathological parameters such as histological types and layers. We reported desregulation of bcl-2 and $NOS_2$ expression during progression from oral white lesion, lichen planus and leukoplakia to squamous cell carcinoma. The obtained results were as follows: 1. Immunohistochemical analysis with monoclonal antibodies to bcl-2 oncoprotein and $NOS_2$ in formalin-fixed paraffin-embedded tissue sections revealed that bcl-2 expression is restricted to the basal cell layer and $NOS_2$ was mild expressed only in subepithelial inflammatory cells in normal human mucosa. There wasn't specific finding of those in lichen planus and leukoplakia. 2. Bcl-2 immunoreactivity in severe epithelial dysplasia or CIS occurs throughout the epithelium, $NOS_2$ reactivity in most superficial layer were noted. 3. In well-differentiated squamous cell carcinomas, mostly bcl-2 was overexpressed. In moderated and poor squamous cell carcinomas, the expression of $NOS_2$ was increased and that of bcl-2 was decreased. 4. The immunoreactivity of bcl-2 was 12.5% of normal mucosa, 30% of leukoplakia, 44% of lichen planus and 67% of carcinoma in situ. In carcinoma, those were 43%, 50% and 67% according to differentiation, respectively. 5. The immunoreactivity of $NOS_2$ was 25% of normal mucosa, 70% of leukoplakia, 78% of lichen planus and 100% of carcinoma in situ and epithelial dysplasia. In carcinoma, those were higher in moderated(100%) and poor(83%) squamous cell carcinomas than in well differentiated type(71%). 6. The expression of bcl-2 and $NOS_2$ by Western blot was increased highly in lichen planus and leukoplakia. Therefore, the expression of bcl-2 was increased in the white and precancerous lesions and that was decreased by differentiation of carcinoma. However, $NOS_2$ immunoreactivity in carcinoma in situ was lower than those in moderated and poor squamous cell. These findings suggest that the interaction of bcl-2 and $NOS_2$ may be roled importantly in growth and development of carcinoma.

저작근 및 경부근에서 압력통각역치와 기능시 근활성도 간의 관계

신민,김재창,Shin, Min,Kim, Jae-Chang 대한안면통증구강내과학회 1997 Journal of Oral Medicine and Pain Vol.22 No.2

This study aimed at evaluating tile relationship between pressure pain threshold(PPT) and electromyographic(EMG) activity in 30 healthy volunteers and 30 patients with temporomandibular disorders. PPTs were determined with electric pressure algometry over masseter, temporalis anterior, sternocleidomastoid, and trapezius muscle during resting and clenching. To obtain more reliable result, two examiners measured PPTs two times on each muscles, randomly. Resting and clenching EMG activity and tenderness of all muscles were measured to evaluate the relationship with PPTs. The collected data were processed by SAS/STAT program. The obtained results were as follows : 1. Pressure pain thresholds in tendered muscles were lower than those in non-tendered muscles. This tendency was more prominant in masticatory muscles than in cervical muscles and in clenching than in resting. 2. There ware a tendency of higher PPTs in unaffected side than in affected side, but there were no significant difference statistically. 3. There wert no difference of PPTs between in preferred side and in ipsilateral side, significantly. 4. There was a significantly positive correlation between resting and clenching PPTs, but there were no correlation between PPTs and EMG activities. 5. Comparison of EMG activity between in higher group and in lower group by resting PPTs didn't show any significant difference. But resting EMG activity in the higher group of clenching PPTs were lower, on the contrary, clenching activity were higher than those in lower groups of clenching PPTs. From this results, the author concluded that the clenching PPTs was more important than resting PPTs in diagnosis of muscle dysfunction. And the author recommanded that all of three following test were performed for the proper diagnosis and treatment of orofacial Pain : muscle tenderness, EMG activity, and PPT.

표면마취가 저작근 및 경부군의 압력통각역치에 끼치는 영향에 관한 연구

신민,Shin, Min 대한안면통증구강내과학회 1997 Journal of Oral Medicine and Pain Vol.22 No.1

Pressure pain thresholds are routinely used in orofacial pain research to evaluate the response of deep orofacial tissues to mechanical stimulation. Like other psychophysical measurements, however, this technique must stimulate cutaneous tissues before stimulating deeper tissues. This study aimed at evaluating the influence of the cutaneous hypoesthesia on the pressure pain threshold in 30 healthy volunteers. PPTs were determined with electric pressure algometry over masseter, temporalis anterior, sternocleidomastoid, and trapezius muscle before and after skin hypoesthesia. A local anesthetic cream and a control cream were applied following a placebo-controlled double-blind design and PPTs were reassessed. Two examiners measured PPTs two times on each muscles, randomly. And the EMG activity of all muscles were measured to evaluate the relationship with PPTs. The collected data were processed by SAS/STAT program. The obtained results were as follows : 1. There were a tendency to increase PPTs after than before cutaneous hypoesthesia, but, there were no significant difference statistically. 2. PPTs were consistently higher in anterior temporalis than in masseter muscle. 3. In all occasions, PPTs were higher in males than in females(p<0.001). 4. A statistically significant correlation was obtained from values of intra-examiners and inter-examiners in all measured muscles. 5. A significantly positive correlation was not found between PPT and functional EMG activity.

菓器│花器

신민 중앙대학교 예술대학 공예학과 1976 卒業作品硏究文集 - 工藝專攻 Vol.1976 No.-

교합안정장치가 근력과 근지구력에 미치는 영향

신민,양춘호 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.6

This study was purposed to investigate the effects of occlusal splints on the muscle strength and muscle endurance. The subjects were 42 general undergraduate students(14), weight lifting(14) and rowing players (14) were participated as experimental and control group. Measured items were back muscle strength, grasping power, sit-up, chinning etc. It was measured before application of occlusal splints, 6 weeks and 12 weeks after. The obtained results was analyzed by SPSS PC 11.0 statistical program. The results were as follows; 1. In general undergraduate group, there is significantly differed only on grasping power item between experimental and control groups. There were significant differences on back muscle strength, grasping power and chinning between before occlusal splint and 12 weeks after occlusal splint. 2. There were no differences between experimental and control groups in weight lifting players, but all scores of measured items were higher in 12 weeks after occlusal splint than before occlusal splint. 3. In rowing players, there were no significant difference between two groups, however, there were differed on back muscle strength, grasping power and chinning scores between 12 weeks after and before occlusal splint. Therefore, long term use of occlusal splint, at least for 12 weeks, were helpful for enhancement of muscle strength and endurance.

한·중 전통문양의 비교 연구 : 길상 문양을 중심으로

신민 한국공예학회 2001 조형디자인연구 Vol.4 No.2

The patterns, like language and words, has their own indigenous shape depending upon the circumstances in which their users have lived. Thus they have peculiar forms all over the world, and so the Oriental patterns and the Western patterns are distinctively different. However, it can be said that they include not only regional aspects but also religious aesthetics. In Orient, the flourising of the Confucius Buddhist culture has created these patterns by stirring people's imagination abundantly. In this respect, it will be significantly meaningful to make a comparative analysis of the patterns of the two neighboring countries, Korea and China, which have had a close relationship historically. Therefore, this study aims to investigate these two patterns through their comparative analysis with special reference to their lucky physiognomy. As for the patterns showing lucky physiognomy which have been used as a generally popular culture, they were settled as popular arts on the basis of Taoism in China whole they were practically used in the daily life due to the Buddhist arts in Korea. In addition, they symbolize having many sons, living a long life and a wish in China, while in Korea they symbolize a small wish by the unit of family and community. It can be accepted that this represents the basic human desire. It can be finally concluded that these patterns are widely used in food, clothing and housing today, but that they can be developed better when they will be expressed in accordance with modern life so that their true meaning can be brought to modern men.