Oxymetazoline의 가토장편운동(家兎腸片運動) 억제작용(抑制作用) 등장성(等張性) 및 등장성(等張性) 기록방법(記錄方法)의 비교(比較)

신동호,최수형,Shin, Dong-ho,Choi, Soo-hyung 대한수의학회 1985 大韓獸醫學會誌 Vol.25 No.1

The inhibitory action of oxymetazoline on the spontaneous movements of isolated intestinal strips of the rabbit and the effects of antagonists upon the oxymetazoline actions were assessed with recordings through both isometric and isotonic transducers, and comparisons were made between both methods of recording. There were significant differences between the slopes of regression equations calculated from log dose response curves of oxymetazoline obtained from jejunum and those from ileum. But no difference was noted between both recordings either through isotonic transducer or through isometric transducer. The $ID_{50}$ of oxymetazoline obtained from the recording through isotonic transducer was $6.31{\times}10^{-7}M$ in jejunum and $3.16{\times}10^{-8}M$ in ileum. The recording through isometric transducer gave the values of $5.01{\times}10^{-7}M$ in jejunum and $1.07{\times}10^{-8}M$ in ileum. The $pA_2$-values of prazosin to oxymetazoline calculated from the recording through isotonic transducer were 8.13 in jejunum and 8.31 in ileum and the recording through isometric transducer gave the values of 7.29 and 8.26 in jejunum and ileum, respectively. The $pA_2$-values of phentolamine to oxymetazoline obtained from the recording through isotonic transducer were 8.18 in Jejunum and 9.31 in ileum and those from the recording through isometric transducer were 7.75 and 8.13 in jejunum and ileum, respectively. These results indicate that there are no significant differences between recordings either through isotonic transducer or through isometric transducer in assessing inhibitory responses of intestinal movement to certain drugs.

화력발전소 굴뚝 미세먼지 측정을 위해 개발한 이젝터-다공튜브 희석장치의 희석비 검증

신동호,김영훈,서현수,홍기정,김학준,김용진,한방우,이가영,천성남,황정호,Shin, Dongho,Kim, Young-Hoon,Hong, Keejung,Kim, Hak-Joon,Kim, Yong-Jin,Han, Bangwoo,Lee, Ga-Young,Chun, Sung-Nam,Hwang, Jungho 한국입자에어로졸학회 2019 Particle and Aerosol Research Vol.15 No.3

The exhaust emissions from coal-fired power plants have received much attention because coal-fired power plants are the one of the largest sources of particulate matter (PM) emissions in South Korea. To measure the PM10 and PM2.5, we developed the novel diluter which is comprised of ejector and porous tube in series. The dilution ratio must be defined to calculate particle concentrations of the sampled air as well as to probe match for the isokinetic sampling. For this reason, we verified the dilution ratio of the developed diluter by the flow rate, numerical solution, gas concentration and particle concentration. The ejector-supplied flow rates were 10-50 L/min and the porous tube-supplied flow rates were 30, 50 L/min in this study. All methods above showed similar dilution ratios to each other within 10 % error rate. The dilution ratio was confirmed by comparing mass concentrations before and after the dilution process.

광산란법을 이용한 국내 석탄화력발전소 굴뚝에서 배출되는 PM₁₀, PM_2.5 측정 및 분석

신동호,김영훈,홍기정,이건희,박인용,김학준,김용진,한방우,황정호,Shin, Dongho,Kim, Younghun,Hong, Kee-Jung,Lee, Gunhee,Park, Inyong,Kim, Hak-Joon,Kim, Yong-Jin,Han, Bangwoo,Hwang, Jungho 한국입자에어로졸학회 2020 Particle and Aerosol Research Vol.16 No.4

Air pollutants emitted from chimneys of coal-fired power plants are considered to be a major source of fine particulate matter in the atmosphere. In order to manage fine particle in the chimney of a coal-fired power plant, it is necessary to know the concentration of fine particle emitted in real time, but the current system is difficult. In this study, a real-time measurement system for chimney fine particle was developed, and measurements were performed on six coal-fired power plants. Through the measurements, the mass concentration distribution according to the particle size could be secured. All six chimneys showed bimodal distribution, and the count median diameters of each mode were 0.5 and 1.1 ㎛. In addition, it was compared with the gravimetric measurement method, and it was determined that the relative accuracy for PM10 was within 20%, and the value measured using the developed measuring instrument was reliable. Finally, three power plants were continuously measured for one month, and as a result of comparing the concentration of PM10 according to the amount of power generation, it was confirmed that the PM10 discharged from the chimney increased in the form of an exponential function according to the amount of power generation.

탄소섬유 시트 방전극의 입자 크기 별 집진 특성 및 공기청정기로의 응용

신동호,우창규,홍기정,김학준,김용진,한방우,shin, Dongho,Woo, Chang Gyu,Hong, Keejung,Kim, Hak-Joon,Kim, Yong-Jin,Han, Bangwoo 한국입자에어로졸학회 2018 Particle and Aerosol Research Vol.14 No.3

The market for improving the indoor air quality is continuously increasing, and air cleaners are the representative products. As interest in indoor air quality increases, so are the ultrafine particle which are harmful to the human body. Despite its many advantages, electrostatic precipitators are less used in indoor air due to ozone production. In this study, the carbon fiber sheet was applied to the discharge electrode and compared with the conventional tungsten wire discharge electrode. The particle collection efficiency and the amount of ozone generation were measured for 10-100 nm particles. Furthermore, it was applied to commercial air purifier with electrostatic precipitator to compare particle removal performance. The carbon fiber sheet type discharge electrode generates a small amount of ozone, and thus it can be applied to improve indoor air quality.

방사선 조사 마우스에서 분죽(Phyllostachys nigra var. henenis Strapf)잎 추출물의 효과

신동호,김종춘,김세라,오헌,박인철,오기석,정희종,장종식,김성호,Shin, Dong-Ho,Kim, Jong-Choon,Kim, Se-Ra,Oh, Heon,Park, In-Chul,Oh, Ki-Seok,Chung, Hee-Jong,Jang, Jong-Sik,Kim, Sung-Ho 대한수의학회 2003 大韓獸醫學會誌 Vol.43 No.1

This study was performed to determine the effect of Phyllostachys nigra var. henenis Strapf leaf extract on jejunal crypt survival, endogenous spleen colony formation and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of gamma-radiation. Phyllostachys nigra var. henenis Strapf administration before irradiation (I.P.: 125 mg/kg of body weight, at 24 hours before irradiation) resulted in an increase of the formation of endogenous spleen colony (p<0.01). The frequency of radiation-induced apoptosis was also reduced by pretreatment of Phyllostachys nigra var. henenis Strapf (I.P.: 280 mg/kg or 28 mg/kg of body weight, at 24 hours before irradiation, p<0.01). These results indicated that Phyllostachys nigra var. henenis Strapf might be a useful radioprotector, especially since it is a relatively nontoxic natural product. Further studies are needed to characterize better the promotion nature of Phyllostachys nigra var. henenis Strapf and its components.

세기변조방사선치료의 정도관리를 위한 두경부 팬톰 제작에 관한 연구

신동호,박성용,김주영,이세병,조정근,김대용,조관호,Shin Dongho,Park Sung-Yong,Kim Joo Young,Lee Se Byeong,Cho Jung Keun,Kim Dae Yong,Cho Kwan Ho 한국의학물리학회 2005 의학물리 Vol.16 No.1

m3 (BrainLAB Inc., Germany)를 이용한 두경부 IMRT의 정도관리에서 테이블과 갠트리의 위치에 따라 테이블에 의한 선량감쇠가 일어나 정확한 처방 선량을 측정할 수 없다. 이 문제를 해결하기 위해 두경부 종양의 세기변조방사선치료를 위해 Brain Lab사의 환자테이블 mount를 이용해 설치할 수 있는 원통형 두경부 팬톰을 제작하였다. 이를 이용하여 환자테이블에 의한 선량 감쇠를 측정하고 실제 임상에 적용함으로써 테이블에 의한 선량 감쇠로 인한 선량분포의 차이를 확인할 수 있었다. 측정결과 환자테이블에 의한 점 선량의 감쇠가 최대 약 35%가 났으며 실제 환자 치료계획에 대한 정도관리에서의 절대점 선량의 경우 5.4%의 선량차이를 나타냈다. For the QA of IMRT treatment of head and neck cancer by using M3 (BrainLAB Inc. Germany), it is not easy to measure delivery dose exactly because the dose attenuation appears by the couch according to the position of table and gantry. In order to solve this problem, we fabricated head and neck phantom which would be implemented on the couch mount of Brain Lab Inc. We investigated dose attenuation by the couch and found the difference of dose distribution by the couch, in the applying this phantom to the clinic. After measurement, we found that point dose attenuation was 35% at maximum and dose difference was 5.4% for a point dose measurement of actual patient quality assurance plan.

Isocenter Optimal Matching Shift Algorithm to Verify the Dose Distribution in Intensity-Modulated Radiation Therapy through the Stochastic Property

신동호,박성용,박천건,Dong Oh Shin,조관호,윤명근,Se Byeong Lee,Suk Lee 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.51 No.5

Dose distribution verification using a film for assuring the quality of intensity-modulated radiation therapy for patients with head and neck cancer using an m3 (Brain Lab.) did not complement the planned dose distribution at points having large gradients in dose variations, although the isocenter position had few discrepancies. An effective way to solve this problem would be precisely investigate the reason for this unexpected shift and then to recover it to the correct position. Using Mathlab 7.1, we have developed a new software program called ``isocenter optimal matching shift algorithm" (ISOMSA). To find the optimal ISOMSA for finding isocenter shifts, we compared two methods, one based on a statistical method of minimizing the variance (SMMV) and the other based on a statistical method of minimizing the mean (SMMM) of the setup error. To evaluate the two methods, we compared verification results for seven patients at the National Cancer Center by using both methods. The results showed that the number of points revealing more than a 9 \% difference in SMMV was 2.86 \%, which was less than the percentage, 8.0 \%, from SMMM. While the average of the maximum percentage difference between the plan and the film in SMMV was 14.06 \%, the percentage was 15.23 \% in SMMM. These experimental results suggest that SMMV works better than the SMMM in finding setup errors. Clinically, this result is very important because the dose difference between the plan and the film may be analyzed more precisely by using the proposed method to reduce systematic errors

Crypft+ : Python/PyQt 기반 AES와 HASH 알고리즘을 이용한 파일 암복호화 시스템

신동호,배우리,신형규,남승진,이형우,Shin, Dongho,Bae, Woori,Shin, Hyeonggyu,Nam, Seungjin,Lee, Hyung-Woo 한국사물인터넷학회 2016 한국사물인터넷학회 논문지 Vol.2 No.3

본 논문에서는 IoT 시스템 또는 개인별 문서 파일 관리 과정의 보안성을 향상시키기 위해 개선된 파일 암복호화 시스템인 Crypft+를 개발했다. Crypft+ 시스템은 Python을 이용하여 핵심 보안 모듈을 개발하였으며, PyQt를 사용하여 사용자 인터페이스를 설계 및 구현하였다. 또한 가장 보안성이 뛰어난 AES 기반 대칭키 암호 알고리즘과 SHA-512 기반 해쉬 알고리즘을 이용하여 컴퓨터 시스템 내부에 저장된 중요 파일에 대한 암호화 및 복호화 과정을 수행할 수 있도록 구현하였다. 또한 Cx-Freezes 모듈을 사용하여 구축된 프로그램을 exe 기반 실행 파일로 변환하는 기능을 구현하였으며, 프로그램 사용에 있어 이해를 돕는 설명서를 프로그램 내부에 포함시켜 직접 다운로드 받을 수 있도록 구현하였다. In this paper, we have developed Crypft+ as an enhanced file encryption/decryption system to improve the security of IoT system or individual document file management process. The Crypft+ system was developed as a core security module using Python, and designed and implemented a user interface using PyQt. We also implemented encryption and decryption function of important files stored in the computer system using AES based symmetric key encryption algorithm and SHA-512 based hash algorithm. In addition, Cx-Freezes module is used to convert the program as an exe-based executable code. Additionally, the manual for understanding the Cryptft+ SW is included in the internal program so that it can be downloaded directly.

Corynebacterium pseudotuberculosis에 의한 유산양의 가성결핵 증례

신동호,송윤경,변재원,김하영,김형순,우계형,이오수,정병일,Shin, Dong-Ho,Song, Yun-Kyung,Byun, Jae-Won,Kim, Ha-Young,Kim, Hyoung-Soon,Woo, Gye-Hyeong,Lee, O-Soo,Jung, Byeong Yeal 대한수의학회 2010 大韓獸醫學會誌 Vol.50 No.1

Caseous lymphadenitis (CLA) is a chronic and contagious disease of sheep and goats caused by Corynebacterium (C.) pseudotuberculosis. A four-year-old female Saanen dairy goat was submitted to the Animal Disease Diagnostic Center at National Veterinary Research and Quarantine Service. The clinical signs of the goat were emaciation, abortion and quadriplegia. The multifocal nodules of lymph nodes were encapsulated and filled with whitish caseous contents on the cut surface. Histopathologically, lymph nodes displayed suppurative and necrotizing granulomas. Caseous necrosis was diffusely observed in the center of the lymph nodes. Gram positive bacilli were shown in the lesions. C. pseudotuberculosis was isolated and confirmed by the biochemical tests and PCR assay. Based on clinical signs, histopathological examination and bacterial isolation, we diagnosed this case as CLA. To our knowledge, this is the first report of CLA in a Saanen dairy goat in Korea.

2급 와동 수복 시 한국 치과 지사들의 복합레진 사용 실태 연구

신동호,박세은,양인석,장주혜,이인복,조병훈,손호현,Shin, Dong-Ho,Park, Se-Eun,Yang, In-Seok,Chang, Ju-Hea,Lee, In-Bog,Cho, Byeong-Hoon,Son, Ho-Hyun 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.2

본 연구는 2008년 1월 현재 한국 치과의사들의 복합레진 사용 실태에 관한 설문 조사로서, 2급 와동을 수복하는 증례에서 치과의사의 면허 년도, 교육 배경 및 진료환경 등에 따라 수복재료의 선택, 복합레진의 사용여부 및 사용방법, 문제점 등을 비교하였다. 한국 치과의사들을 대상으로 2급 와동 수복에 관한 17 문항의 설문지를 제작하였다. 이 설문지는 시술자 정보, 2급 와동의 수복으로 크게 2부분으로 나누어진다. 이 설문지는 대한치과의사협회를 통해 12,193명의 치과의사들에게 E-메일로 발송되었다. 이 중 2,612개의 메일이 수신 확인되었고 840 개의 설문지가 작성되어 회신되었다 수신 확인된 메일 수에 대한 회신된 메일 수의 비율 (회신율)은 32.2%이었고, 이 자료는 SPSS 프로그램에서 카이제곱 분석을 이용하여 교차 분석하였다. 답변자의 비율은 면허년도를 기준으로 $1998{\sim}2007$년에 면허를 취득한 그룹 (한국 전체 치과의사의 33.3%, 추정년령 26-35세)이 60.3%로 1997년 이전에 면허 취득한 그룹 (한국 전체 치과의사의 66.7%, 추정 년령 36세 이상)의 39.7%보다 높은 것으로 나타났다. 또한 이들이 근무하는 병원은 개인의원 (77%)이 가장 많았고, 남자 치과의사 (79%)가 많았다. 복합레진 수복에 대한 지식은 학생 때 수업이나 학회 세미나를 통하여 (83.4%) 얻은 것으로 나타났다. 2급 와동 수복 시 재료 선호도를 살펴보면 금인레이가 65.7%를 차지하고 있고 복합레진 직접 수복은 12.1%로 낮게 나타났다. 2급 와동의 복합레진 직접 수복 시 시술 방법에 있어서는 러버댐을 사용하지 않거나 잘 사용하지 않는 그룹의 비율 (74.4%)이 더 많았고, 격벽법으로는 mylar strip (53.4%)이나 metal matrix (33.8%), Palodent system (6.5%)를 사용하였다. 충전은 적층법 (99.6%)을 사용하는 것으로 나타났으며, 시술 시 인접면 형성을 가장 어려워하였다(57.2%). 2-step 접착시스템 (76%)이 3-step 접착시스템 (16%)보다 많이 사용되고 있었다. 사용하는 레진 제품으로는 Z250 (20%)이 가장 많이 사용되고 있었다. The purpose of this study was to assess the current materials, methods and difficulties according to the year of licence and educational background of Korean dentists in Class II direct composite resin restorations. Total 17 questions were included in the questionnaire. Questions were broadly divided into two parts: first. operator's information. and second. the materials and methods used in Class II posterior composite restoration. The questionnaire was sent to dentists enrolled in Korean Dental Association via e-mail. Total 12,193 e-mails were distributed to dentists. 2,612 e-mails were opened, and 840 mails (32.2%) were received from respondents. The data was statically analyzed by chi-square test using SPSS(v. 12.0.1, SPSS Inc. Chicago, IL, USA). Male dentists among respondents was 79%. 60.3% of the respondents acquired their licences recently (1998-2007), and 77% practiced in private offices. 83.4% have acquired their knowledge through school lectures, conferences and seminars. For the Class II restorations, gold inlays were preferred by 65.7% of respondents, while direct composite resin restorations were used by 12.1 % amalgam users were only 4.4% of respondents. For the restorative technique, 74.4% of respondents didn't use rubber dam as needed. For the matrix. mylar strip (53.4%), metal matrix (33.8%) and Palodent system (6.5%) were used. 99.6% of respondents restored the Class II cavity by incremental layering. Obtaining of the tight interproximal contact was considered as the most difficult procedure (57.2%) followed by field isolation (21 %). Among various bonding systems, 22.6% of respondents preferred SE Bond and 20.2% used Single Bond. Z-250 was used most frequently among a variety of composite resins.