디스플레이용 미니 LED의 환경요인에 대한 특성 평가

김지명(Ji-Myung Kim),김강호(Kang-Ho Kim),신경호(Jyung-ho Shin),김유신(Yu-Sin Kim),조영주(Yeong-Ju Cho),채성기(YSung-Gi Chae) 한국조명·전기설비학회 2024 한국조명·전기설비학회 학술대회논문집 Vol.2024 No.5

임상가검물에서 불리된 Staphylococcus의 Penicillinase 산생에 관하여

신경호,이원길,김재식,김중명 대한병리학회 1979 Journal of Pathology and Translational Medicine Vol.13 No.3

原發性肝癌의 診斷을 위한 血淸 Alkaline Phosphatase Isoenzyme의 電氣泳動像

申敬鎬,金在植,金重明 慶北大學校 醫科大學 1975 慶北醫大誌 Vol.22 No.2

肝癌 128例에 對해서 血淸 ALPI電氣泳動像과 아울러 主要 臨床 및 檢査所見을 觀察하여본 結果 年齡的으로 40∼60代가 87.5%로 대부분을 차지하였으며 男女比는 4:1로 男子가 훨씬 많았다. 主要 臨床症狀 및 理學的 所見으로는 腹部不快感 또는 疼痛, 腹部膨滿感, 肝腫大, 腹水 및 黃疸等이 가장 頻繁하였으며 檢査所見中 血淸總蛋白量은 82.8%에서 그리고 總bilirubin 은 65.6%에서 正常範圍內에 속했으며 A/G 比는 64.8%에서 逆轉을 보였다. 血淸 GOT 및 GPT 는 各各 84.4% 및 71.1%에서 增加된 活性値를 보였으며 prothrombin time 은 89.5%에서 延長되었다. 肝走査像은 73.0%에서 冷所를 보였고 HBs-Ag 및 α-FP 은 各各 27.2% 및 40.0%에서 陽性이었고 肝細胞診과 肝針生檢上 各各 96.7% 및 86.7%에서 原發性肝癌으로 確診되었다. 血淸 ALP 및 LDH 의 總活性値와 LDH_5分劃은 各各 62.5%, 73.0% 및 59.3%에서 增加되었으며 이들의 平均値는 臨床的으로 診斷된 肝癌에서 各各 5.6±1.88 B-L U, 894.8±526.55 Worblewski U 및 14.50±3.87%였고 이 中 肝細胞診 및 肝針生檢으로 確認된 例에서는 各各5.8±2.9 U, 921.8±547.4U 및 14.20±7.2%로서 비슷한 値를 나타내었다. 血淸 ALPI電氣泳動像은 臨床的으로 診斷된 肝癌의 77.3%에서 fast liver 分劃을 보였으며 50%에서는 α_1만, 9.38%에서는 α_1+alb. 分劃을 그리고 17.97%에서는 alb.分劃만을 나타내었다. 또한 肝細胞診 및 肝針生檢으로 確診된 肝癌의 76.47%에서 fast liver 分劃을 볼 수 있었으며 48.53%는 α_1만, 5.88%는 α_1+alb.을 그리고 22.06%에서는 alb.分劃만을 나타내었다. 肝疾患中 α_1分劃만 나타나는 境遇는 原發性肝癌이 76.2%로 가장 많았으며 α_1+alb.分劃이 出現하는 境遇는 原發性肝癌이 50%였고 alb.分劃만 나타나는 例는 急性肝炎이 39.0%로 가장 많았다. 血淸 ALPI 電氣泳動像과 HBs-Ag, α-FP, 肝走査像, 肝細胞診 및 LDHI 電氣泳動像과의 相關關係를 보면 α_1分劃의 出現과 α-FP 만이 有意한 關聯性을 보였다. 또한 血淸 LDHI 電氣泳動像과 α-FP, HBs-Ag, 肝走査像 및 肝細胞診과의 關聯性을 보면 癌細胞의 發見과 LDH_5分劃의 增加와만이 有意한 相關關係를 보였다. For the evaluation of usefulness of electrophoretic patterns of serum alkaline phosphatase isoenzyme in the diagnosis of hepatoma, the author observed the electrophoretic patterns of serum ALPI in 128 patients with hepatoma diagnosed clinically, of which 68 patients were confirmed by aspiration cytology and/or needle biopsy. Also clinical and other labolatory findings were observed. Of the 128 hepatoma patients, 102 were male and 26 female, and a peak incidence of age was al the fifth to seventh decade (87.5%). The commonest symptoms were abdominal discomfort and/or pain (59.4%) followed by abdominal swelling (18.0%). The common physical findings were hepatomegaly (93.8%), ascites (35.9%), and jaundice (35.9%). The levels of serum total protein and bilirubin were within reference values in 82.8%, 65.6% respectively, and A/G ratio reversed in 64.8%. The activities of serum GOT and GPT were increased in 84.4%, 71.1% respectively. The prothrombin time was prolonged in 89.5% of the cases. The cold areas in the liver scanning, HBs-Ag, and alpha-fetoprotein in serum were observed in 73.0%, 27.2% and 40.0% respectively. Of 60 aspiration cytologies, 58(96.7%) were positive and two were negative for cancer cell. Of 15 percutaneous liver biopsies, 13(86.7%) were positive and 2 were negative for tumor. The activities of serum ALP, LDH, and LDH_5 were increased in 62.5%, 73.0%, and 59.3% of cases respectively. In the mean values of serum ALP, LDH, and LDH_5, there was no significant difference between clinically diagnosed and pathologically proven hepatoma. In the electrophoreric patterns of serum ALPI of the hepatoma patients, the fast liver fractions were observed in 77.3%(α_1;50%, α_1±alb. ;9,38%, alb.;17.9%) in the clinical hepatona and 76.4% (α_1;48.53%, α_1 alb. ;5.88%, alb.;22.06%) in the pathologically proven hepatoma respectively. During the determinations of electrophorectic patterns of serum ALPI of various liver diseases, the α_1 fractions were seen in hepatoma (76.2%), liver abscess (6.0%), chronic liver disease (6.0%), metastatic liver cancer (4.8%). The α_1±alb. fractions were seen in hepatoma (50.0%), intrahepatic obstructive jaundice (29.2%), liver cirrhosis (16.7%), and clonorchiasis (4.2%). The alb. fractions were seen in acute viral hepatitis (39.0%), extrahepatic obstructive jaundice (18.3%), liver cirrhosis (14.1%), and hepatoma (10.8%) respectively. In the correlation between electrophoretic patterns of serum ALPI and HBs-Ag, alpha-fetoprotein, liver scanning, cytology, and electrophoretic patterns of serum LDHI, the appearance of α_1 fraction showed positive correlations to the alpha-fetoprotein. In the correlation between electrophoretic patterns of serum LDHI and HBs-Ag, alpha-fetoprotein, liver scanning, and cytology, the positive cytology was positive correlation to the increased LDH5 fractions.

항문 직장부에 발생한 악성 흑색종

신경호,김재식,김중명,장은숙 대한병리학회 1979 Journal of Pathology and Translational Medicine Vol.13 No.2

API 20E法에 依한 腸內細菌의 同定

金重明,申敬鎬,金在植,金京善 慶北大學校 醫科大學 1980 慶北醫大誌 Vol.21 No.2

病的 資料에서 分離된 425菌株를 API 20E에 의하여 同定하고, 이 菌株들을 從來 方法에 의하여 同定된 菌株와 一致性을 보기 위하여 從來方法으로 이를 다시 同定하였던 바 그 成積은 다음과 같이 要約할 수 있었다. Salmonella typhi 8株에서는 從來 方法은 87.5%에서 API 20E에 의한 同定에 一致되었고, Enterobacter aerogenes 14株는 92.9%에서 Proteus mirabilis 15株는 93.3%에서 Enterobacter cloacae 62株는 96.8%에서 Escherichia coli 127株는 97.6%에서 各各 一致되었고, Enterobacter agglomerans 5株, Enterobacter sakazakii 2株, Hafnia alvei 1株 및 Yersinia enterocolitica 4株에서는 一致되는 것은 한 株도 없었으며, Shigella flexneri 4株 Shigella boydii 2株, Shigella sonnei 6株, Salmonella paratyphi A 6株, Arizona hinshawii 2株 Citrobacter freundii 57株, Klebsiella pneumonia 69株, Klebsiella ozanae 1株, Serratia marcescens 31株, Proteus vulgaris 3株, Proteus morganii 3株, Proteus rettgeri 2株 및 Providencia stuartii 1株는 完全히 一致되었고, 全體的으로는 平均 95.1%에서 一致되었다. We have identified 425 strains of Enterobacteriacea by the API 20 E from various kinds of clinical materials, and in order to see the agreement of the results of tests with the API 20 E and conventional method, the strains of Enterobacteriaceae identified by the API 20 E were identified again by the conventional method. The results of the identifications were as follows; The percent of the agreement of identification results of tests with the API 20 E and conventional method was 87.5 in eight strains of the Salmonella typhi, was 92.9 in 14 strains of the Enterobacter aerogenes, 93.3 in 15 strains of the Proteus mirabilis, 96.8 in 62 strains of the Enterobacter cloacae, 97.6 in 127 strains of the Escherichia coli, and there was no the agreement of the identification result of tests with the both in five strains of the Enterobacter agglomerans, in two strains of the Enterobacter sakazakii, in one strain of the hafnia alvei, and in four strains of the yersinia enterocolitica. But four strains of the Shigella flexneri, two strains of the Shigella boydii, six strains of the Shigella sonnei, six strains of the Salmonella paratyphi A, two strains of the Arizona hinshawii, 57 strains of the Citrobacter freundii, 69 strains of the Klebsiella pneumoniae, one strain of the Klebsiella ozaenae, 31 strains of the Serratia marcescens, three strains of the Proteus vulgaris, three strains of the Proteus morganii, two strains of the Proteus rettgeri, and one strain of the Providencia stuartii agreed completely in the both identification results.

병적재료에서의 분리균과 그 균의 약제감수성

김중명,신경호,김재식 慶北大學校 醫科大學 1978 慶北醫大誌 Vol.19 No.2

1976년 1월 초부터 1977년 12월 말까지 만 2년간 경북대학교 의과대학 부속병원 임상병리과에 의뢰된 혈액등 21종의 병적재료 4315예에서 Staphylococcus aureus등 25종 2882균주를 분리 동정하고 그중 일부의 균에 대해서 감수성검사를 하였던 바 다음과 같이 요약할 수 있었다. 분리균종별로는 총 2882주중 E.coli가 601주(20.9%)로 가장 많이 분리되었으며 2중감염 751예(37.2%)와 3중감염 56예(2.8%)가 있었다. 재료별로 보면 혈액에서는 202주가 분리되었는데 Staphylococcus epidermidis와 Escherichia coli가 각 36주(17.8%) Samonella group D34주(16.8%)의 순으로 많았다. 농에서는 총 547주중 Staphylococcus epidermidis 156주(28.5%) Escherichia coli 98주(17.9%)의 순으로 많았고 객담에서는 총 758주중 Micrococcus 218주(28.8%) Alpha Streptococcus 183주(24.1%)등이 많았으며 인후도말에서는 총 397주중 Micrococcus 76주(19.1%) Alpha Streptococcus 64주(16.1%)등이 많았고 소변에서는 총 429주중 Staphylococcus epidermidis 156주(36.4%) Escherichia coli 108주(25.2%)등이 많았으며 대변에서는 총117주중 Escherichia coli가 72주(61.5%)로 가장 많았다. 직장도말에서는 총 130주중 Escherichia coli가 73주(56.2%)로 가장 많았으며 비강도말에서느 총 87주중 Staphylococcus epidermidis가 31주(35.6%)로 가장 많았으며 척수액에서는 총 44주중 Streptococcus pneumonae가 13주(29.5%)로 가장 많았으며 제대에서는 총 48주중 Escherichia coli가 16주(33.3%)로 가장 많았고 늑막액에서는 총 40주중 Staphylococcus epidermidis가 11주(27.5%)로 가장 많았으며 복수에서는 총 25주중 Escherichia coli가13누(52.0%)로 가장 많았다. 약제감수성태도에 있어서는 Staphylococcus, Streptococcus, Streptococcus pneumoniae등의 그람양성 구균들은 Oleandomycin, Lincomycinem에 비교적 감수성이 높은 편이었고 N.menin.는 Lincomycin, Cephaloridine, Aminosidine등에 비교적 높은 감수성을 보였으며 그람 음성 간균중 E.coli는 Gentmycin, carbenicillin, Bactrim등에 비교적 높은 감수성을 보였으며 Salmonella arizonae는 Kanamycin, Gentamycin 및 Aminosidine에 Proteus vulgaris는 Aminosidine에, Pseudomonas aeruginosa는 Colistin에 비교적 높은 감수성을 나타내었다. 전체적으로 볼 때 감수성은 대체로 낮은 경향을 나타내었으며 그 중에서도 특히 Penicillin과 Strreptomycin에는 매우 낮은 감수성을 보였다. A total of 2882 strains consistin of 25 species of micoorganisms were isolated during the period from January 1st, 1976 to December 31th, 1977, from 4315 cases of various clinincal specimens at Kyungpook National University hospital and the susceptibility of these organisms to various antibiotics were tested. Of total 2882 strains isolated, E. coli, was the most frequently isolated with 601 strains(20.9%). among 2017 Culture-positive cases, there were 751 cases (37.2%) in which two species of microorganisms were isolated from one specimen and 56 cases (2.8%) in which three species of micoorganisms were isolated from one specimen. Staphylococcus aureus was isolated most frequently from pus and a majority of them wre susceptible to novobiocin (65.5%), aminosidine (59.0%), oleandomycin (57.3%). Staphylococcus epidermidis was isolated frequently from urine and pus, and sensitive to oleandomycin (63.4%) cephaloridine (48.0%) and novobiocin (47.4%). Micrococcus was isolated most frequently from sputum and sensitive to aminosidine (54.2%), carbenicillin (44.2%) cephloridine (36.8%). Alpha hemolytic Streptococcus was isolated frequently from sputum and throat swab and sensitive to cleosin (58.3%), oleandomycin (54.4%) and cephaloridine (51.6%). Beta hemolytic Streptococcus was frequently isolated from sputum, and showed relatively low susceptibility to carbenicillin (46.4%), lincomycin (42.3%), oleandomycin (40.0%), and cephalordine (39.3%). Streptococcus pneumoniae was isolated frequently from sputum and throat swab, and was highly susceptible to cleosin (100.0%), minocin (88.9%), carbenicillin (85.7%) and lincomycin (73.5%). Neisseria meningitidis was isolated from blood and C.S.F., was highly susceptible to lincomycin (85.7%), but not susceptible to the other drugs tested. Escherichia coli was isolated frequently from urine, pus, sputum and stool, and was susceptible to bactrim (61.5%), gentamycin (61.0%), and carbenicillin (60.3%). Enterobacter aerogenes was isolated frequently from pus, sputum and urine, and was susceptible to gentamycin (45.6%) and colistin (38.0%). Proteus vulgaris was isolated frequently from pus, and sensitive to aminosidine (60.0%), not so susceptible to other drug tested. Pseudomonas aeruginosa was isolated most frequently from pus and showed high susceptibility to cleosin (74.0%). Penicillin and streptomycin showed very poor antimicrobial activity against all micoorganisms isolated.

병적재료에서의 분리균과 그 균의 약제 감수성

김중명,신경호,김재식 慶北大學校 醫科大學 1978 慶北醫大雜誌 Vol.19 No.2