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다결정 산화갈륨/다이아몬드 이종 박막 성장 및 열처리 효과 연구
서지연,김태규,신윤지,정성민,배시영,Seo, Ji-Yeon,Kim, Tae-Gyu,Shin, Yun-Ji,Jeong, Seong-Min,Bae, Si-Young 한국결정성장학회 2021 한국결정성장학회지 Vol.31 No.6
본 연구에서는 산화갈륨의 방열 특성 향상을 위해 산화갈륨/다이아몬드 이종 박막 성장을 진행하였다. 먼저, 핫필라멘트 화학기상증착법을 이용하여 다결정 다이아몬드를 증착시킨 후, 미스트 화학기상증착법을 통해 450~600℃ 사이의 온도구간에서 산화갈륨 박막을 성장시켰다. 열처리 전후 비교를 통해 500℃에서 산화갈륨/다이아몬드 계면 분리 현상이 발생함을 확인하였다. 이는 비정질과 결정질이 혼재된 산화갈륨 박막이 성장된 후, 냉각 과정에서 열팽창계수의 차이로 인해 계면이 분리된 것으로 판단하였다. 따라서, 본 연구를 통한 산화갈륨/다이아몬드 계면의 물리적 안정성을 통해 산화갈륨의 열물성 보완및 고전력 반도체로의 활용이 기대된다. In this study, Ga<sub>2</sub>O<sub>3</sub>/diamond layers were grown on Si substrates to improve the thermal characteristics of Ga<sub>2</sub>O<sub>3</sub> materials. Firstly, diamond thin film was grown on Si substrates by hot-filament chemical vapor deposition. Afterward, Ga<sub>2</sub>O<sub>3</sub> layer was grown in the growth temperature range of from 450~600℃ by mist chemical vapor deposition. We found that layer separation happens at the Ga<sub>2</sub>O<sub>3</sub>/diamond interface at the growth temperature of 500℃. This is attributed to the different thermal expansion coefficient of the mixture of amorphous and crystalline structures during cooling process. Therefore, this study might contribute to the heat-sink-layer bonded power semiconductor applications by stabilizing the thermal properties at Ga<sub>2</sub>O<sub>3</sub>/diamond interface.
서지연 ( Seo Ji Yeon ),신민환 ( Shin Min Hwan ),최용훈 ( Choi Young Hoon ),김기철 ( Kim Ki Chul ),정명숙 ( Myung Sook Jung ),임경재 ( Lim Kyoung Jae ),최중대 ( Choi Jung Dea ) 한국농공학회 2008 한국농공학회 학술대회초록집 Vol.2008 No.-
This study was conducted to discribe characteristics of Non-point Source(NPS) Pollution discharge from a coal mining area in korea. Study Area is location at in Jeonduri, Dogyeup, Samchuck, Gangwon province where there is a coal mining workplace. Monitoring system was installed at a drainage channel and flow rate and water samples were collected from Sept. 2007 to Jun. 2008. Two and 5 rainfall events were monitored in 2007 and 2008, respectively. collected water samples sere analyzed with respect to SS, BOD, COD<sub>Cr</sub>, COD<sub>Mn</sub>, T-N, T-P, and TOC. It was obesrved that the runoff and water quality were largely influenced by mine drainage. Event Mean Concentration(EMC) of the analyzed indexes were : SS 86.35~94.90 kg/day, BOD 3.77~7.56 kg/day, COD<sub>Cr</sub> 26.90~51.60 kg/day, T-N 1.45~2.12 kg/day, T-P 0.20~0.21 kg/day and TOC 1.83~2.33 kg/day in 2007 and SS 12.3~523.9 kg/day, BOD 3.9~56.1 kg/day, COD<sub>Cr</sub> 18.8~97.8 kg/day, COD<sub>Mn</sub> 5.7~38.6 kg/day, T-N 0.2~9.8 kg/day, T-P 0.0~2.9 kg/day and TOC 3.0~7.7kg/day in 2008. Also, NPS pollution loads were SS 1,368.8~1,984.1 kg/day, BOD 56.6~128.9 kg/day, COD<sub>Cr</sub> 385.7~933.7 kg/day, T-N 23.4~44.5 kg/day, T-P 2.1~4.8 kg/day and TOC 0.7~4.4 kg/day in 2007. and SS 64.8~2673.1 kg/day, BOD 18.0~1080.2 kg/day, COD<sub>Cr</sub> 52.9~1552.1 kg/day, COD<sub>Mn</sub> 34.2~153.9 kg/day, T-N 1.6~55.8 kg/day, T-P 0.04~10.9 kg/day and TOC 15.3~125.9kg/day in 2008. As the study progresses in the future, runoff and pollution loads will be updated.
Bone Morphogenic Protein-7의 복막섬유화 억제효과와 기전
서지연 ( Ji Yeon Seo ),하헌주 ( Hun Joo Ha ),유미라 ( Mi Ra Yu ),김재룡 ( Jae Ryong Kim ),안면환 ( Myun Whan Ahn ),이희발 ( Hi Bahl Lee ) 대한신장학회 2007 Kidney Research and Clinical Practice Vol.26 No.1
Purpose: Bone morphogenic protein (BMP)-7, a member of TGF-β1 superfamily, is an endogenous antifibrotic protein highly expressed in normal kidney. It is not known, however, whether human peritoneal mesothelial cells (HPMC) express BMP-7 or if BMP-7 protects against peritoneal fibrosis and by what mechanism. We examined the effect of BMP-7 overexpression in TGF-β1-induced epithelial-mesenchymal transition (EMT) of HPMC and in TGF-β1 signaling in HPMC to elucidate the mechanisms of antifibrotic effect of BMP-7. Methods: Growth arrested and synchronized HPMC were stimulated with 2 ng/mL of TGF-β1 to induce EMT. HPMC were transiently transfected with adenovirus-mediated human BMP-7 (AdBMP-7) or with GFP (AdGFP). EMT was defined as downregulation of E-cadherin and upregulation of α-smooth muscle actin (SMA). Results: HPMC constitutively expressed BMP-7 mRNA and protein. BMP-7 mRNA and protein expression were significantly inhibited by 50 mM D-glucose, 2x diluted commercial peritoneal dialysis solution, and 2 ng/ml of TGF-β1. Transfection of AdBMP-7 resulted in 2.5-fold increase in BMP-7 mRNA expression in HPMC. TGF-β1 significantly decreased E-cadherin and increased α-SMA expression in GFP transfected cells. BMP-7 overexpression effectively reversed TGF-β1-induced E-cadherin and α-SMA expression and significantly suppressed TGF-β1-induced phosphorylation of Smad2/3, ERK1/2, JNK, and p38 MAPK in HPMC as compared to GFP transfected cells. Conclusion: BMP-7 is an endogenous antifibrotic protein and downregulation of BMP-7 in HPMC by high glucose, PD solution, and TGF-β1 may permit the development of peritoneal fibrosis during long-term PD. Our data demonstrate that BMP-7 overexpression reverses TGF-β1-induced EMT of HPMC and consequent peritoneal fibrosis possibly through inhibition of Smad2/3 and MAPK phosphorylation.
사업초기단계에서의 건물 에너지 사용량 및 비용 평가 모델
서지연(Seo, Ji-Yeon),이종식(Lee, Jong-Sik),전재열(Chun, Jae-Youl) 대한건축학회 2013 大韓建築學會論文集 : 構造系 Vol.29 No.8
Various programs have been developed to predict the energy consumption of a building as a result of recent increased social interest in the environmental friendliness of construction as measured by energy efficiency. The goal of environmental-friendliness, which is achieved by predicting the energy consumption of a building, can be realized in the design stage by applying a variety of technologies, planning factors and planning systems. However, most energy analyzing engines are only suitable for use in the advanced stages of design because of the large amount of design information that must be entered. Thus, because the simulation programs currently used are not suitable for use in the early stages of design, this study suggests a prediction logic that provides an overview of the energy consumption of a building according to its size, scope, and purpose by analyzing statistics collected by government agencies.