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      • KCI등재

        Risk of cervical dysplasia among human papillomavirus-infected women in Korea: a multicenter prospective study

        박윤,김태진,황창선,조치흠,정대훈,성석주,이재관,허수영,기미경,성재현,기모란 대한부인종양학회 2019 Journal of Gynecologic Oncology Vol.30 No.3

        Objective: Human papillomavirus (HPV) infection is the most important risk factor for cervical cancer, which progresses from precursor lesions with no symptom if left untreated. We compared the risk of cervical dysplasia among HPV-positive Korean women based on HPV types and infection patterns. Methods: We observed participants of a 5-year multicenter prospective cohort study, comprising HPV-positive women with either atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion of the cervix at their enrollment. Follow-ups, comprising cytology and HPV DNA testing results, were included in the final analysis. Incidence was calculated for each infection pattern (persistent infection, incidental infection, and clearance). To investigate cervical dysplasia risk, we used Cox proportional hazard models adjusted for variables that were significantly different among infection patterns. From April 2010 to September 2017, 71 of 1,027 subjects developed cervical dysplasia more severe than high-grade squamous intraepithelial lesion of the cervix. Results: Of these 71 subjects, persistent infection, incidental infection, and clearance were noted in 30, 39, and 2 individuals, respectively. Based on changes in DNA results during follow-up, cumulative incidence was 27.2%, 10.4%, and 0.5% for persistent infection, incidental infection, and clearance, respectively. Compared to clearance, the adjusted hazard ratios for cervical dysplasia were 51.6 and 24.1 for persistent and incidental infections, respectively (p<0.001). Conclusion: Individuals persistently infected with the same HPV types during the follow-up period had the highest risk of severe cervical dysplasia. Hence, it is necessary to monitor HPV types and infection patterns to prevent severe cervical precancerous lesions.

      • KCI등재

        한국인 인간관계의 문화적 특성과 척도개발-온정적 인간관계

        박윤,심형인,이숙종 한국문화및사회문제심리학회 2014 한국심리학회지: 문화 및 사회문제 Vol.20 No.4

        본 연구는 한국적 인간관계의 문화적 특성을 발견하기 위하여 수행되었다. 연구1에서는 한국인·한국사회의 특성에 관한 전문서적 21권과 한국인 인간관계의 문화적 특성에 관한 선행연구를 검토하여 한국적 인간관계의 특성을 이해하고 이를 대표할 수 있는 예비문항 45개를 선별하였다. 이를 활용하여 국내 대학생을 대상으로 설문조사를 실시하였고 문항-총점 간 상관관계를 분석하여 5개의 예비문항을 삭제하고 40개의 예비문항으로 탐색적 요인분석을 실시하였다. 탐색적 요인분석 결과 6개 하위요인(32개 문항)으로 분석되었고, 측정문항의 내용타당도를 검토하는 과정에서 의미가 중복되는 문항을 통합·수정하여 총 20개로 재구성하였다. 연구2에서는 연구1에서 재구성한 20개의 예비문항을 활용하여 국내 일반인을 대상으로 설문조사를 실시하였고, 탐색적 요인분석 결과 ‘우호적 관계, 정, 조화, 관계유지중시’의 4개 하위요인을 발견하였다. 확인적 요인분석을 통해 측정모형의 타당도를 검토하고 개념타당도를 검토하는 과정에서 3개의 측정문항을 삭제하여 17개 측정문항을 온정적 인간관계 척도로 확정하였다. 이후 온정적 인간관계 척도와 유사 개념 간의 상관관계를 분석함으로써 변별타당도를 분석하였다. 또한 본 연구의 결과를 토대로 본 척도의 4개 하위요인을 한국의 문화적 특성 관점에서 해석하고 본 척도가 갖는 의의와 한계점을 논의하였다. The purpose of this study was to examine the cultural characteristics of Korean interpersonal relationships. A total of 45 preliminary items were selected through book and literature review about the characteristics of the Korean or Korean society in study 1. The first survey data were collected from the Korean university students. Through the item analysis and Exploratory Factor Analysis(EFA), 4 factors composed of 32 items were extracted. Four factors were found: ‘friendly attitude, harmony, jeong(interpersonal affection), keeping relationship’, and using content analysis, 20 items were refined. Study 2 was conducted with the data collected from the Korea adults. As the result of carrying out EFA and Confirmatory Factor Analysis(CFA), the final 17 items were fixed as an affective relationships scale of the Korean. And CFA were implemented to evaluate discriminative validity. Finally, the implications and limitations of this study were discussed.

      • KCI등재

        Association of Dietary Vitamin D and Calcium With Genetic Polymorphisms in Colorectal Neoplasia

        박윤,김정선 대한암예방학회 2015 Journal of cancer prevention Vol.20 No.2

        The incidence trends of colorectal cancer have varied over time, and there is wide geographical variation across the world. Regarding colorectal cancer, diverse modifiable environmental or intrinsic risk factors have been investigated. This review summarizes the effects of both dietary intake of vitamin D and calcium in particular and diet-associated genetic factors on colorectal cancer risk. Wesearched the electronic database PubMed for articles published between January 2000 and March 2015. We reviewed case-control studies that included dietary factors, genetic polymorphisms, and gene-diet interactions in association with colorectal cancer risk. Overall, 21 studies were selected as eligible studies. These studies demonstrated that dietary consumption of vitamin D and calcium may decrease the risk of colorectal cancer or adenoma. Colorectal carcinogenesis was discussed in conjunction with dietary factors and mediating genetic factors. The epidemiological findings suggested that the gene-diet interactions may possibly alter the associations between dietary intake, genetic polymorphisms, and the risk of colorectal cancer. However, the reported effects of the same potential factors on colorectal cancer risk were inconsistent, depending on the study population and geographical location. This finding may imply the necessity of considering the environmental differences and genetic variations existing between individuals or specified populations. Therefore, further studies are required to investigate modifiable risk factors in diverse locations to derive useful implications for colorectal neoplasia

      • 교사의 성격 유형과 스트레스 대처 방식에 대한 연구

        박윤,최낙천 조선대학교 학생지도연구소 2005 生活指導硏究 Vol.24 No.-

        This study is to investigate the relationship between personality types and stress coping types of teachers. In this study. PFQ was performed for 115 teachers to find their personality types and the stress coping style was scaled for their ways of stress coping. The teachers' personality styles are divided into introversion vs. extroversion: stableness vs. unstableness: tender-mindedness vs. tough-mindedness: dependence vs. independence: low superego vs. high superego: and low creativity vs. high creativity. Stress coping style was sub-scaled into 9 styles: aggressive coping styles-assertive. strategic and positive: coping styles y emotional relaxation. self-motivation. tension releasing. wishful thinking: coping style by avoidance-self-rebuking. abnormal activity, pursuing social acceptance. The relationship between the personality styles and stress coping styles was investigated. 1 First. introvert-extrovert personality styles show differences in the aggressive stress coping styles-assertive and positive coping: the stress coping by emotional relaxation-tension releasing: and coping style by avoidnace-pursuing social acceptance. In theses. the extrovert uses the above sub-scaled stress coping styles than the introvert does. Second, for the second personality types, the group with stable personalirty uses the positive coping styles while the one with unstableness would use the negative coping styles more. Third, for the tender-and tough-mindedmess, the former group uses strategic, tension releasing and wishful thinking coping styles more than the latter group. Fourth, the independence group uses aggressive and emotional relaxation stress copting styles more than the dependent group. Fifthe, for the weak and strong superego groups, which are divided by the strength of their super egos, the teachers with strong superego use assertive, strategic, and wishful thinking styles to cope with stresses effectively. Sixth, there is no significant fifference in stress coping style for the low and high creativity groups. In conclusion, the extrovert. stable, tender-mindedness. independent, and strong superego teachers cope with stresses more effectively.

      • 바이오매스로부터 생산한 바이오차에 의한 수질오염물질 흡착 : Adsorption of Water Pollution by Biochar Produced from Biomass

        박윤,정수연,정은서,신윤정,이은주,이재원 전남대학교 농업과학기술연구소 2022 농업생명과학연구동향 Vol.60 No.-

        Biochar is produced from lignocellulosic biomass (wood, agricultural and forestry waste, etc.) through thermal decomposition at high temperature. Water pollution (pesticides, dyes, heavy metals, and volatile organic compounds [VOCs]) can be efficiently removed by biochar. In particular, waste biomass is typically used as fuel or thrown away; thus, it is necessary to determine a valuable utilization for it. The process of biochar production is simple and suitable for the production of porous structures. In this paper, 1) biochar production and its characteristics based on biomass types, 2) research trends on the adsorption of water pollution (pesticides, dyes, heavy metals, VOCs) on biochar, and 3) expected effects are discussed.

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