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      • 정책제언-대학과목선이수제의 소개 및 성공적 도입을 위한 방안

        박선미,Park, Seon-Mi 한국대학교육협의회 2007 大學敎育 Vol.151 No.-

        대학과목선이수제(University-level Program; UP)는 고등학생들에게 대학 수준의 과목을 학습할 수 있는 기회를 제공하고, 그 평가 결과를 대학입학 후에 학점으로 인정받을 수 있게 함으로써 교육의 수월성 및 고교-대학 간 학습연계성을 추구하는 제도이다. 이러한 대학과목선이수제는 교육인적자원부와 한국대학교육협의회의 주도로 2008년 1월부터 본격 시행된다. 이에 새로이 도입된 대학과목선이수제에 대하여 소개하고, 제도의 성공적인 정착을 위한 방안에 관해 살펴보기로 한다.

      • 좌측 유방 방사선치료 시 4D-CT를 이용한 심장의 체적 및 선량변화에 대한 연구

        박선미,천금성,허경훈,신성필,김광석,김창욱,김회남,Park, Seon Mi,Cheon, Geum Seong,Heo, Gyeong Hun,Shin, Sung Pil,Kim, Kwang Seok,Kim, Chang Uk,Kim, Hoi Nam 대한방사선치료학회 2013 대한방사선치료학회지 Vol.25 No.2

        목 적: 좌측 유방암 환자 치료 시 4D-CT를 이용하여 기존에 호흡이 고려되지 않았던 치료와 비교하여 심장의 체적 변화와 호흡에 따른 심장의 선량 차이를 알아보고자 한다. 대상 및 방법: 2012년 3월부터 5월까지 본원에 내원한 2문 접선조사로 치료받은 좌측 유방암 환자 10명을 대상으로 하였다. 좌측 유방이 충분히 포함될 수 있도록 FOV (Field-of-view)를 설정하고 자유 호흡 상태의 일반 CT (Free-Breathing CT)와 4D-CT를 통해 영상을 획득하였다. 선량은 50.4 Gy (1.8 Gy/28 fraction)로 필요에 따라 추가적으로 계획용표적체적(PTV: Planning target volume)에 전자선 1문 조사 9 Gy (1.8 Gy/5 Fraction)를 처방하였고 선량체적히스토그람(Dose Volume Histogram)를 이용하여 심장에 받는 선량과 체적을 비교 분석하였다. 결 과: Free-Breathing CT 영상과 4D-CT 영상의 심장에 받는 선량과 체적을 비교 분석한 결과 4D-CT 영상에서 심장의 체적이 최대 40.5% 크게 나타났으며 또한 심장의 총 흡수선량도 최대, 최소, 평균선량이 최대 8.8%, 27.9%, 37.4% 높게 나타났다. 결 론: 4D-CT를 촬영하여 호흡을 고려한 치료계획이 Free-Breathing CT 영상으로 치료 계획한 것 보다 환자의 심장선량이 높게 조사된 것으로 나타났다. 따라서 심장과 근접한 좌측 유방 방사선치료 시 심장박동에 의한 심장의 체적변화를 고려한 치료계획을 세워야 할 것으로 사료된다. Purpose: We investigate the results of changed heart volume and heart dose in the left breast cancer patients while considering the movements of respiration. Materials and Methods: During the months of March and May in 2012, we designated the 10 patients who had tangential irradiation with left breast cancer in the department of radiation Oncology. With acquired images of free breathing pattern through 3D and 4D CT, we had planed enough treatment filed for covered up the whole left breast. It compares the results of the exposed dose and the volume of heart by DVH (Dose Volume histogram). Although total dose was 50.4 Gy (1.8 Gy/28 fraction), reirradiated 9 Gy (1.8 Gy/5 Fraction) with PTV (Planning Target Volume) if necessary. Results: It compares the results of heart volume and heart dose with the free breathing in 3D CT and 4D CT. It represents the maximum difference volume of heart is 40.5%. In addition, it indicated the difference volume of maximum and minimum, average are 8.8% and 27.9%, 37.4% in total absorbed dose of heart. Conclusion: In case of tangential irradiation (opposite beam) in left breast cancer patients, it is necessary to consider the changed heart volume by the respiration of patient and the heartbeat of patient.

      • 소아 비만이 간기능에 주는 영향

        박선미,안상용,김현미,황옥분,박대정,김현주,강순주,오윤정,김순기,Park, Seon-Mi,An, Sang-Yong,Kim, Hyeon-Mi,Hwang, Ok-Bun,Park, Dae-Jeong,Kim, Hyeon-Ju,Gang, Sun-Ju,O, Yun-Jeong,Kim, Sun-Gi 한국건강관리협회 2006 한국건강관리협회지 Vol.4 No.1

        Purpose: With remarkable increase in the prevalence of childhood obesity, nonalcoholic fatty liver disease increased, The aim of this study is to evaluate the prevalence of the increase liver enzymes, lipid levels and fasting blood glucose level in normal and obese children. Methods: A total of 2206 elementary students were grouped according to obesity index; normal group and obesity group(mild, moderate, severe). Aspartate aminotransferase(AST, SGOT) and alanine aminotrausferase(ALT, SGPT) were measured with tota1 cholesterol, triglyceride and fasting blood glucose. Results: Compared with the 2.7% of ALT > 50 IU/L in normal group, obese groups showed significantly higher prevalence; 6.7% in mild obesity group, 11.8% in moderate group and 15.0% in severe group. The prevalence of hypertriglyceremia was 12,4% in normal weight group, which is significantly lower than obesity group(mild obesity group 24.8%, moderate and severe 32.1% each). Conclusion: The prevalence of nonalcoholic fatty liver increased along with severity of obesity. Of Nutritional assessment, intervention, and preferably prevention are necessary for health promotion elementary students.

      • SCOPUSKCI등재

        소화기 영역에서의 줄기세포 연구

        박선미 ( Park Seon Mi ) 대한소화기학회 2004 대한소화기학회지 Vol.43 No.4

        Stem cells are undifferentiated cells capable of undergoing self-renewal and differentiation into a variety of cell types. They are derived from adult tissues (adult stem cells) as well as embryonal blastocysts (embryonic stem cells). Embryonic stem cells have pleuripotent capacity able to form tissues of all three germ layers but many ethical controversies concerning resource allocation or methods of harvesting are arising. Recently, many studies have demonstrated the multipotency of adult stem cells, but the mechanism of the plasticity remains to be determined yet. Several studies have suggested the possibilities of application of stem cells or tissue specific cells to regenerate gastroenterologic diseases such as liver cirrhosis, hepatitis, or inherited metabolic disorders. However, most of those trials are still limited to animal models, although anecdotal claims of successful therapy in humans have been reported. Even though the expectations and the promise of cell therapy are high, clinical efficacy has not been definitely demonstrated at this time. Thus, the application of cell therapy cannot be recommended to the patients outside the clinical trial setting. (Korean J Gastroenterol 2004;43:221-225)

      • SCOPUSKCI등재

        담석으로 인한 십이지장 폐쇄증

        박선미(Seon Mee Park),서장원(Jang Won Seo),최호순(Ho Soon Choi),이성구(Sung Koo Lee),김명환(Myung Hwan Kim),민영일(Young Il Min),이영주(Young Joo Lee),이승규(Sung Kyu Lee) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.4

        A 67-year-old man with gallstone was admitted to the Asan Medical Center for right upper quarant abdominal pain and intermittent vomiting. Physical examination showed normal except soft palpable mass accompanying tenderness on epigastrium. Abdominal coputered tomograpy revealed ill defined low density mass at GB fossa. Gastrofiberscopic exam showed huge dark brown colored stone impacted with fluid collection of GB fossa. 3.0 cm sized calcifying mass located at duodenun at bulb of duodenum. A barium meal outlines the stone which is obstructing the duodenum. At operation, 3.0 cm sized egg shaped gallstone was impacted in a markedly edematous duodenum. Partial cholecystectomy and enterolithotorny were done and he was recovered uncomplicated. Gallstone obstruction of duodenum is a rare condition but awareness of this complication is important because early diagnosis and proper management prevent high mortality. Duodenal obstruction secondary to a gallstoue is a rare entity, usually reported as 1 to 3 per cent of patients with gallstone ileus. (Korean J Gastroenterol 1996;28:587 - 591)

      • SCOPUSKCI등재

        십이지장 궤양 발생에 있어서 H . pylori와 위상피화생의 연관에 대한 연구

        박선미(Seon Mee Park),양석균(Suk Kyun Yang),홍원선(Weon Seon Hong),민영일(Young Il Min),이인철(In Chul Lee) 대한소화기학회 1995 대한소화기학회지 Vol.27 No.6

        N/A Background/Aims: H. pylori infection and gastric metaplasia are frequently associated in patients with duodenal ulcers. However, the pathogenesis of duwlenal ulcer in relation to H, pilori infecri<in and gastric metaplasia has not reacbed a consistent result, yet. The aim of this study v,as to assess whether H. pylori infection and gastric metapla.ia contrihute to duodenal ulcerogenesis. Methods: Multiple endoscopic biopsy specimens were tnken frorn duodenum and gastric antrum of ?I subjects(21 active duodenal ulcers; 30 scarred duodenal ulcers; 20 normal controls). The specimens were examined histologically for the presence ot' H. pylori, gastric metaplasia, and degree of gastritis and duodenitis. Rapid tissue urease test was performed t'or detection of H, pi krri infc cti<in. Results: The positive rate of H. pylrri in gastric antrurn was not significantly different aniong ttlTCC groups, while it was increasing in duodenum, I,e., normal controls(3%'), scarred DU's(37,r), active DU's(62%) in ascending order. The incidence of duodenal gastric metaplasia in the active DU'.I was 95.2% in contrast with the scarred duodenal ulcer's(72.07<) and the nonnal contrnls(2i.04) Diffuse gastric metaplasia lesions were more prevalent in active duodenal ulcers. 1n the duodenum, a strong association was shown between the H. pylrri and gastric rnetaplasia. The severity ot' duodenitis were significantly increased in the order ot' groups of normal controls, scarrecl duodena1 ulcers, and active duodenal ulcers. In duoclenum, there was a strong association with the grade c>f' intlammation anci H. pylori. Conclusions: These results suggest that gaslric metaplasia in the duodenum and concurrent H. pilori infection may play a synergistic role in the pathogene.I. Vt' duodenal ulcer. (Korean J Gastroenterol 199S;27: 617-62S)

      • KCI등재

        유치원 교육활동 지도자료에 나타난 동작활동의 실태에 관한 연구

        박선미(Park Seon Mi) 한국육아지원학회 2007 육아지원연구 Vol.2 No.2

        본 연구의 목적은 유치원 교육활동 지도자료에 나타난 동작활동의 수와 동작 유형, 경향을 알아보고, 각 수준별로 제시된 동작의 특성을 파악함으로써 유치원 교육활동 지도자료의 동작활동이 유아의 발달과 수준을 고려하여 계획되었는지를 알아보는데 있다. 이를 위해 유치원 교육활동 지도자료의 제시된 활동 중 92개의 동작활동을 선정하고, 이를 생활주제별로 나누어 동작의 유형과 생활주제에 따른 경향을 살펴 보았으며, 마지막으로 각 활동을 통해 습득할 수 있는 동작 유형을 수준별로 나누어 분석하였다. 연구 결과, 유치원 교육활동 지도자료의 동작활동은 생활주제와 수준별로 활동 수에 차이가 있었다. 동작활동의 유형은 생활주제가 진행됨에 따라 난이도에 차이가 있었으나 일관성이 없었다. 또한, 각 수준별 동작활동에서 나타나는 기본 동작, 구조적 동작, 창의적 동작은 수준별로 차이가 있기 보다는 1, 2수준 모두 특정 동작 위주로 계획되어 있었다. The purpose of this study is to see if the movement activities in the guiding materials for the kindergarten educational activities were designed with considering the development stages and the levels of early children. For this study, 92 movement activities in the guiding materials for the kindergarten educational activities were chosen. The results of this study revealed as follows. First, the types of movement activities were different each other in themes and levels. Second, the more themes are progressed, the more difficult the types of movement activities, but it was short of consistency. Third, the types of movement were not distributed variously over the levels. Implications for teacher and suggestions for further study-the use of teacher as a variable and the study of a program based on early children's development-were provided.

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