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2008 ASCO Review: 위암 및 위 위장관기질종양
박도중 대한임상종양학회 2008 Korean Journal of Clinical Oncology Vol.4 No.2
Thousands of cancer studies were presented at the 44th annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago, IL, from May 30 to June 3, 2008. The Oral Abstract Session on Gastrointestinal (Noncolorectal) Cancers featured nine presentations. Two of the talks discussed the results of phase III trials of adjuvant and first-line treatments for gastric cancer. The presentations at the Sarcoma Session reviewed issues related to the roles of chemotherapy and the clinical prognostic features, the optimal use of targeted agents and the challenges in assessing their benefit for patients suffering with gastrointestinal stromal tumors (GISTs).
고도비만환자에게 시행한 로봇 루와이 위우회술 1예 및 로봇 위소매절제술 1예 보고
박도중,안상훈,이주희,김형호 대한내시경복강경외과학회 2011 Journal of Minimally Invasive Surgery Vol.14 No.2
Obesity is associated with high mortality. Bariatric surgery is considered the only evidence-based approach to sustainable weight loss. The most popular bariatric surgeries are Roux- en-Y gastric bypass, gastric banding and sleeve gastrectomy. The laparoscopic approach is favored over the open method for its good recovery. Recently, the robotic system was applied to bariatric surgery, and was reported to have strengths during suturing and anastomosis. On the other hand, there is no report of robotic bariatric surgery in Korea. In the present study, robotic Roux-en Y gastric bypass and robotic sleeve gastrectomy was performed successfully on morbidly obese patients.
Saccharomyces Cerevisiae Hansen CBS 5926의 경구 투여요법이 위절제 환자의 위장관 증상 및 영양에 미치는 영향
박도중,이혁준,이건욱,양한광,Park, Do-Joong,Lee, Hyuk-Joon,Lee, Kuhn-Uk,Yang, Han-Kwang 대한위암학회 2006 대한위암학회지 Vol.6 No.2
목적: 본 연구는 Saccharomyces boulardii가 위암으로 위절제술을 받은 환자에서 위장관 증상과 영양상태를 호전시키는지 평가하고자 하였다. 대상 및 방법: 2002년 12월부터 2004년 7월까지 서울대학교병원 외과에서 조기위암으로 위절제술을 받은 환자 90명을 대상으로 하여 시험군과 위약군(대조군)을 무작위 배정하여 12주 복용하게 하였다. 투약 전, 투약 12주 후, 투약종료 4주 후에 담당의사와 환자에 눈가림법을 적용하여 두 군의 위장관 증상과 영양 지표(혈액검사 및 체위)를 비교하였다. 결과: 남녀 비는 2.3 : 1이었고 평균 연령은 $56.3{\pm}10.2$세였다. 수술은 위아전절제술이 69예, 위전절제술이 21예였다. 연구가 시작된 후 중도 탈락한 환자가 14명(15.6%)이었고 이 중 시험군은 5명이었다. 위장관 증상에 있어서 시험군과 대조군 간의 의미 있는 차이는 보이지 않았다(P>0.05). 전체적으로(n=76)투약 종료 4주 후의 혈중 알부민이 시험군에서 더 높게 나왔다(P=0.046). 위아전절제술과 위전절제술을 나누어 비교하였을 때, 위아전절제술을 받은 환자들(n=57)에서 역시 투약 종료 4주 후의 알부민이 시험군에서 더 높게 나왔다(P=0.049). 결론: 위암으로 위절제술을 받은 환자에서 Saccharomyces boulardii를 투여한 시험군에서 혈중 알부민이 높게 나와 Saccharomyces boulardii가 위절제술 후 영양을 호전시키는데 도움을 줄 수 있겠다. Purpose: We aimed to investigate the effect of oral Saccharomyces cerevisiae Hansen CBS 5926 therapy (Saccharomyces boulardii) on gastrointestinal symptoms and nutrition in gastrectomized patients. Materials and Methods: Ninety patients who underwent a gastrectomy due to early gastric cancer were randomly divided into case and control (placebo) groups and were given medicine or placebos for 12 weeks. The gastrointestinal symptom rating and the nutritional status were evaluated by using double blind methods at 4, 16, and 20 weeks after discharge. Results: The ratio of males to females was 2.3 : 1, and the mean age was $56.3{\pm}10.2$ years. The numbers of subtotal gastrectomies and total gastrectomies were 69 and 21, respectively. Fourteen (15.6%) patients dropped, of whom 5 belonged to the case group. Of the remaining 76 patients, those in the case group had higher levels of serum albumin (P=0.046). For patients who underwent subtotal gastrectomy (n=57), the case group had higher level of serum albumin (P=0.049). Conclusion: This double blind study showed that oral Saccharomyces boulardii therapy could improve the postoperative nutrition of gastrectomized patients because gastrectomized patients with oral Saccharomyces boulardii therapy had higher levels of serum albumin than the control group.