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환경 독성 억제효과를 가진 커큐민 나노스피어가 마우스의 사료 효율 및 악취저감에 미치는 영향
박정배 ( Jeong-bae Park ),이영민 ( Young-min Lee ),박문기 ( Moon-ki Park ),민태선 ( Taesun Min ),이세중 ( Sei-jung Lee ) 한국환경과학회 2019 한국환경과학회지 Vol.28 No.2
Curcumin (C<sub>21</sub>H<sub>20</sub>O<sub>6</sub>) is a hydrophobic polyphenol found in turmeric. Although curcumin has been used as a natural medicine, its major limitation is related to poor absorption from the gut. Therefore, we developed a method for preparation of Curcumin Nanospheres (CN) to improve the aqueous-phase solubility of curcumin and investigate the functional role of CN in promoting feed efficiency and odor reduction in mice. CN showed inhibitory effects on actate dehydrogenase (LDH) cytotoxicity induced by ecotoxic substance toluene in gut epithelial HCT116 cells. In addition, the weights of internal organs (liver, heart, kidneys, and spleen) and the levels of serum Glutamate Oxaloacetate Transaminase (GOT), Glutamate Pyruvate Transaminase (GPT), and LDH did not show significant differences between mice administered oral CN for two weeks and compared to the control group. Interestingly, CN not only reduced hydrogen sulfide (H<sub>2</sub>S) and ammonia (NH<sub>3</sub>) levels and fecal odor, but also improved feed efficiency in mice. These results demonstrate that oral nano-delivery of anti-ecotoxicological CN is a functional system to deliver curcumin to the gut to improve feed efficiency and reduce fecal odor in mice.
위성화상을 이용한 고도 1,600 m 이상의 한라산 적설 면적 변화 추적
한경덕,윤성욱,정용석,안진현,이승재,김윤석,민태선,Han, Gyung Deok,Yoon, Seong Uk,Chung, Yong Suk,Ahn, Jinhyun,Lee, Seung-Jae,Kim, Yoon Seok,Min, Taesun 한국환경과학회 2022 한국환경과학회지 Vol.31 No.10
It is necessary to understand the amount of snowfall and area of snow cover of Mt. Halla to ensure the safety of mountaineers and to protect the ecosystem of Mt. Halla against climate change. However, there are not enough related studies and observation posts for monitoring snow load. Therefore, to supplement the insufficient data, this study proposes an analysis of snow load and snow cover using normalized-difference snow index. Using the images obtained from the Sentinel2 satellite, the normalized-difference snow index image of Mt. Halla could be acquired. This was examined together with the meteorological data obtained from the existing observatory to analyze the change in snow cover for the years 2020 and 2021. The normalized-difference snow index images showed a smaller snow pixel number in 2021 than that in 2020. This study concluded that 2021 may have been warmer than 2020. In the future, it will be necessary to continuously monitor the amount of snow and the snow-covered area of Mt. Halla using the normalized-difference snow index image analysis method.