Polyinosinic:polycytidylic acid regulates the regenerative migration of BEAS-2B bronchial epithelial cells via primary cilium formation

Eun-Yi Moon(문은이),Bomi Gweon(권보미) 대한기계학회 2022 대한기계학회 춘추학술대회 Vol.2022 No.4

전통 세라믹 디자인의 하이브리드 접근 연구

문은아 ( Eun A Moon ) 한국디자인트렌드학회 2004 한국디자인포럼 Vol.10 No.-

문화콘텐츠 산업의 상품화에 감각적 체험 마케팅활용에 관한 연구

문은아 ( Eun A Moon ) 한국디자인트렌드학회 2004 한국디자인포럼 Vol.9 No.-

The digital technology is getting introduced into the field of cultural businesses, the level of the customer` s changing demands to goods become more diverse. Therefor, the course of developing goods for getting customers` s changing demands satisfied is getting changing, the consumption culture of customers is getting changing from functional consumptions to sensible consumptions to their preference. Thedesign development for the competitive goods` s development in the field of cultural contents with a high value-added in the industrial area should be connected on the base of putting the marketing for focus on only customers. So, in the thesis, the theory by Sense Experiential Marketing that can appeal to customers` s preference & sense, which is connected to the design developments for a commercial scale of the cultural contents` s businesses, is suggested as a way of marketing which can strengthen the competitive power of cultural businesses if it is made the best useof as the aesthetic principals of the recognizable consistence and the sensible diversity.

신규 퀴놀론 항균제 DW-116 의 소핵시험

문은이(Eun Yi Moon),이진(Jin Lee),최정하(Chung Ha Choi),이치우(Chi Woo Lee),정용호(Yong Ho Chung),윤성준(Sung June Yoon),이덕근(Dug Keun Lee) 한국응용약물학회 1996 Biomolecules & Therapeutics(구 응용약물학회지) Vol.4 No.3

DW-116 {1-(5-fluoro-2-pyridyl)-6-fluoro-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid hydrochloride} is a new quinolone antibiotic with a broad antibacterial spectrum against G(+) and G(-) bacteria. DW-116 was evaluated for the appearance of micronucleus in polychromatic erythrocytes (PCEs) of mouse bone marrow cells after intraperitoneal and oral single administration. We prepared the bone marrow cells at 30hr after drug administration and they were used for measuring PCE with micronucleus. The results showed there was no statistically significant increase in the numbers of PCEs with micronucleus in all DW-116 administered groups compared with a negative control group. The results also showed that the ratio of normochromatic erythrocytes(NCEs) to PCEs of all DW-l16 administered groups was not significantly different from that of a negative control group. These results suggested that DW-116 may not cause any chromosomal damage and it has no in vivo mutagenic potential under these experimental conditions.

다중지능 이론에 기초한 도자 공예 디자인 교육개발 연구-또래집단기 아동의 언어지능 중심으로-

문은아 ( Moon Eun A ) 한국디자인트렌드학회 2006 한국디자인포럼 Vol.13 No.-

Language Development, which is closely tied into the development of intelligence, is one of fundamental prerequisites for the intellectual growth of children, and children should be exposed to a wide variety of educational opportunities to improve their intellectual ability. The purpose of this study was to develop instructions for ceramic art based on the development of the verbal intelligence of children of the gang age, part of the stages of solid expression development. Specifically, it`s attempted to boost interactive exchange among different sorts of intelligences according to multiple intelligences theory. In multiple intelligences theory, the importance of educational environments was accentuated as one of factors to elevate intellectual ability, and ceramic art could provide children with a chance to express their ideas and feelings in a natural manner by simultaneously stimulating their sense of sight and tactile sense. An integrative educational development effort to apply multiple intelligences theory to ceramic art is expected to contribute to enhancing multiple intelligences in diverse contexts.

Full bloom 24

Moon, Eun A(문은아) 한국기초조형학회 2024 한국기초조형학회 작품집 Vol.2024 No.8

신재생에너지시스템을 위한 공통접지가 있는 고승압 DC-DC 컨버터

문은아 ( Eun-ah Moon ),이나원 ( Na-won Lee ) 조선대학교 공학기술연구원 2022 공학기술논문지 Vol.15 No.1

A high step-up gain DC-DC converter with a single switch is introduced in this paper. The introduced DC-DC converter can provide the common ground between renewable energy sources and the negative side of the output load. The extension of an introduced DC-DC converter is also presented to provide the high voltage gain. In addition, the voltage stresses across the devices of the introduced DC-DC converter are still low. The theoretical analysis and a comparison considering other converters previously published in the literature are presented in the paper. In order to validate the introduced DC-DC converter characteristic, a simulation and prototype have been built with a power rating of 450 W.

Iteration and Continuum

문은아(Moon, Eun A) 한국기초조형학회 2023 한국기초조형학회 작품집 Vol.2023 No.12

DW2282 의 용매의존성 항암효과 및 약동력학

문은이(Eun Yi Moon),최청하(Chung Ha Choi),성승규(Seung Kyoo Seong),이진(Jin Lee),유제만(Jei Man Ryu),이문선(Moon Sun Lee),정상헌(Sang Hun Jung),정용호(Yong Ho Chung),이덕근(Dug Keun Lee),윤성준(Sung June Yoon) 한국응용약물학회 1998 Biomolecules & Therapeutics(구 응용약물학회지) Vol.6 No.4

DW2282, (S)-(+)-4-phenyl-1-[N-(4-aminobenzoyl)-indolin-5-sulfonyl]-4,5-dihydro-2-imidazolone hydrochloride, is a novel anticancer agent thought to have an unique mechanism of action on the inhibition of tumor growth. In this study, we estimated in vivo antitumor activities and pharmacokinetics of DW2282 depending on various vehicles. The inhibition rate of tumor growth was increased by 50, 100 and 200 mg/kg of DW2282 in a dose-dependent manner. When DW2282 dissolved in 4 sorts of vehicles was orally single dosed to rats at 50 mg/kg, Cmax of DW2282 in 0.5% CMC.Na was a half as high as those in PG, PG+CP and PG+CP+DW. When DW2282 was orally administered to mice for 5 days, antitumor activity of 130 mg/kg suspended in 0.5% CMC.Na was as effective as that of 65 mg/kg dissolved in the rest of vehicles. Taken together, it is thought that antitumor activities of DW2282 are resulted from the absorption extent of it and related to the vehicle used.

신규 방사성 항암제 DW-166HC 의 소핵시험

문은이(Eun Yi Moon),이진(Jin Lee),이원용(Won Yong Lee),최청하(Chung Ha Choi),이덕근(Dug Keun Lee),유제만(Jei Man Ryu),정용호(Yong Ho Chung),윤성준(Sung June Yoon),박경배(Kyung Bae Park) 한국응용약물학회 1997 Biomolecules & Therapeutics(구 응용약물학회지) Vol.5 No.3

DW-166HC (^(166)Holmium (^(166)Ho)-Chitosan complex) is a new radiopharmaceutic anticancer agent with a broad anti-tumorigenic spectrum, especially against human hepatic cancer. DW-166HC was evaluated for the appearance of micronucleus in polychromatic erythrocytes (PCEs) of mouse bone marrow cells after subcutaneous arid intravenous single administration. Bone marrow cells were prepared at 24 hr and 48 hr after DW-166HC-I (^(165)Ho-Chitosan complex : cold compound) administration and at 24 hr, 72 hr and 2 weeks after DW-166HC (^(166)Ho-Chitosan complex : hot compound) administration. The results showed there was no statistically significant increase of the numbers of PCEs with micronucleus in all DW-166HC-I administered groups compared with a negative control group but there was statistically significant increase of the numbers of PCEs with micronucleus at 24 hr arid 72 hr in all DW-166HC administered groups, which was recovered after 2 weeks from the drug administration. The results also showed the ratio of normochromatic erythrocytes (NCEs) to PCEs of all DW-166HC-I administered groups was not significantly different from that of a negative controi group but there was significant difference of this ratio at 24hr and 72 hr in all DW-166HC administered groups compared with that of negative group, which was also recovered after two weeks from the drug administration. These results suggested that DW-166HC-I may not cause any chromosomal damage but DW-166HC has in vivo mutagenic potential because of its radioactivity.