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- 저자 : 문석호(Seok-Ho Moon) (검색결과 4 건)
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보행 환자에서의 위볼기동맥천공지뒤집기피판을 이용한 허리엉치 부위 연부조직 결손의 치료
문석호,김동석,오득영,이중호,이종원,서제원,안상태,Moon, Suk-Ho,Kim, Dong-Seok,Oh, Deuk-Young,Lee, Jung-Ho,Rhie, Jong-Won,Seo, Je-Won,Ahn, Sang-Tae 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.5
Purpose: Extensive lumbosacral defects after removal of spinal tumors have a high risk of wound healing problems. Therefore it is an effective reconstructive strategy to provide preemptive soft tissue coverage at the time of initial spinal surgery, especially when there is an instrument exposure. For soft tissue reconstruction of a lumbosacral defect, a variation of the gluteal flap is the first-line choice. However, the musculocutaneous flap or muscle flap that is conventionally used, has many disadvantages. It damages gluteus muscle and causes functional disturbance in ambulation, has a short pedicle which limits areas of coverage, and can damage perforators, limiting further surgery that is usually necessary in spinal tumor patients. In this article, we present the superior gluteal artery perforator turn-over flap that reconstructs complex lumbosacral defects successfully, especially one that has instrument exposure, without damaging the ambulatory function of the patient. Methods: A 67 year old man presented with sacral sarcoma. Sacralectomy with L5 corpectomy was performed and resulted in a $15{\times}8\;cm$ sized complex soft tissue defect in the lumbosacral area. There was no defect in the skin. Sacral stabilization with alloplastic fibular bone graft and reconstruction plate was done and the instruments were exposed through the wound. A $18{\times}8\;cm$ sized superior gluteal artery perforator flap was designed based on the superior gluteal artery perforator and deepithelized. It was turned over 180 degrees into the lumbosacral dead space. Soft tissue from both sides of the wound was approximated over the flap and this provided in double padding over the instrument. Results: No complications such as hematoma, flap necrosis, or infection occurred. Until three months after the resection, functional disturbances in walking were not observed. The postoperative magnetic resonance imaging scan shows the flap volume was well maintained over the instrument. Conclusion: This superior gluteal artery perforator turn-over flap, a modification of the conventional superior gluteal artery perforator flap, is a simple method that enabled the successful reconstruction of a lumbosacral defect with instrument exposure without affecting ambulatory function.
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신경구체(Neurosphere) 형성을 통한 교모세포 종양줄기세포의 특성 분석
문석호 ( Seok Ho Moon ),박경순 ( Kyung Soon Park ) 한국조직공학·재생의학회 2012 조직공학과 재생의학 Vol.9 No.1s
Recent evidence suggests that tumors, including glioma, contain a small subpopulation which is responsible to the tumor growth. These cells are called cancer stem cells (CSCs) that are characterized by their ability to undergo self-renewal, differentiate into cell lineages and generate tumors. Since CSCs are recognized as a main cause of tumor initiation and anticancer resistance and cancer recurrence, finding new treatments that can target CSCs may be critical for improving patient survival. However, CSCs are rare in the cancer cell populations and the characteristics of isolated CSCs based on the cell surface marker are not stably maintained. In this study, based on that brain CSCs form neurospheres, we tried to enrich brain CSCs by consecutive subculture of neurospheres. As neurosphere culture passages are increased, the expression of CD133, which is a typical cell surface marker of brain CSCs, is markedly increased. In addition, cell growth was retarded and resistance to anticancer drug cisplatin was increased. Other characteristics of CSCs such as Smad2 phosphorylation and cell migration ability was also increased as passages of neurosphere culture increased. These data suggest that consecutive culture of GBM-derived neurosphere could enrich CSCs like populations.
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CAT.M1 통신을 이용한 자율주행로봇 연동 스마트승강기 구현
홍대오(Dae-Oh Hong),백제현(Je-Hyeon Baek),박건웅(Gun-Woong Park),임광호(Gwang-Ho Lim),문석호(Seok-Ho Moon),이상민(Sang-Min LEE) 한국정보기술학회 2022 Proceedings of KIIT Conference Vol.2022 No.12
현대의 승강기 산업은 사물인터넷(IoT) 기반으로 고도화에 중점을 두고 있지만 공개되지 않는 폐쇄적인 방향으로 발전되었다. 최근에는 운영체제나 시스템, 애플리케이션, 라이브러리 등을 활용한 인터페이스인 오픈 API를 출시하여 다각적인 협업을 추구하고 기존의 방법들 보다 다양한 기능들을 확대해 나아가고 있다. 본 논문에서는 LoRa, NB-IoT와 같이 IoT를 위한 저용량 데이터 통신 기술인 CAT.M1을 활용한 정보통신기술을 바탕으로 하여 차세대 스마트 승강기와 실내 자율주행로봇간의 서비스를 구현하고자 한다. The modern elevator industry has developed in a closed direction that focuses on upgrading based on the Internet of Things (IoT), but is not open to the public. Recently, open API, an interface using an operating system, system, application, library, etc., is being released to pursue diverse collaboration and expand various functions than existing methods. This paper aims to provide services between next-generation smart elevators and indoor autonomous driving robots based on information and communication technology using CATM1, a low-capacity data communication technology for IoT such as LoRa and NB-IoT.
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