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17β-Estradiol이 수컷 송사리의 성적 행위 및 생식능력에 미치는 영향
류지성(Jusugn Ryu),이철우(Chulwoo Lee),박응로(Eung-Roh Park),남성숙(Seong-Sook Nam),남규찬(Kyu-Chan Nam),류홍일(Hong-Il Rhu),전성환(Seong-Hwan Jeon),나진균(Jin Gyun Na),최덕일(Doug Il Choi),박광식(Kwangsik Park) 한국독성학회 2001 Toxicological Research Vol.17 No.2
Sexual behavior and reproductivity of male fish were studied as an in vivo screening method of endocrine disruptors. Male medaka (Oryzias latipes) were exposed to 17β-estradiol at nominal concentrations of 2 and 20 ㎍/l 14 days. After exposure of the chemical, sexual behavior between male medaka and normal female which were injected with prostaglandin F2α just before the test, was ana lysed by using video camera for one hour. Normal control male showed courtship dancing such as following, guarding, dancing and crossing while 17β-estradiol treated male did not show any type of courtship dancing. Furthermore, fecundity and fertility were significantly decreased in the treated group. It was suggested that analysis of sexual behavior could be a useful endpoint for the screening of the endocrine disruptors.