남성 만성신장질환에서 하부요로증상의 양상

류인욱,강덕희,심봉석 대한배뇨장애요실금학회 2007 International Neurourology Journal Vol.11 No.2

음경복합초음파검사의 발기유발제로서 복용약이 주사제를 대체할 수 있는가?

류인욱,윤하나,심봉석,박영요,정우식 대한비뇨의학회 2008 Investigative and Clinical Urology Vol.49 No.7

Purpose: To clarify whether vardenafil can be used as a substitute for intracavernosal injection as a method of induction of penile erection, we compared the outcome of penile duplex Doppler ultrasonography using both methods in the same patient with erectile dysfunction. Materials and Methods: A total of 23 patients underwent penile duplex ultrasonography twice with a one week interval between procedures. Twelve were randomly selected for intracavernosal injection first with prostaglandin E1(PGE1) 20μg and the remaining 11 were initially treated with oral vardenafil 20mg 1 hour before the Doppler study and in addition had visual sexual stimulation using a head-mounted display during the study. The peak systolic velocity(PSV), end diastolic velocity(EDV) and the degree of maximum erectile response were measured and compared between the two groups. Results: Measurements from the PGE1 treatment were not significantly different from those with the vardenafil treatment. The percentage of compatibility between the two methods with regard to hemodynamic diagnosis and pharmaceutical erectile response was as high as 83%(19 of 23) and 91%(21 of 23), respectively. Both methods were tolerable and safe without severe complications. However, in 4 patients where the diagnosis was uncertain, the injection method provided a more accurate interpretation of the penile vascular status with duplex ultrasonography. Conclusions: These results suggest that oral vardenafil can be used as an initial method for inducing penile erection when assessing erectile dysfunction with penile duplex Doppler ultrasonography in selected patients with erectile dysfunction. Purpose: To clarify whether vardenafil can be used as a substitute for intracavernosal injection as a method of induction of penile erection, we compared the outcome of penile duplex Doppler ultrasonography using both methods in the same patient with erectile dysfunction. Materials and Methods: A total of 23 patients underwent penile duplex ultrasonography twice with a one week interval between procedures. Twelve were randomly selected for intracavernosal injection first with prostaglandin E1(PGE1) 20μg and the remaining 11 were initially treated with oral vardenafil 20mg 1 hour before the Doppler study and in addition had visual sexual stimulation using a head-mounted display during the study. The peak systolic velocity(PSV), end diastolic velocity(EDV) and the degree of maximum erectile response were measured and compared between the two groups. Results: Measurements from the PGE1 treatment were not significantly different from those with the vardenafil treatment. The percentage of compatibility between the two methods with regard to hemodynamic diagnosis and pharmaceutical erectile response was as high as 83%(19 of 23) and 91%(21 of 23), respectively. Both methods were tolerable and safe without severe complications. However, in 4 patients where the diagnosis was uncertain, the injection method provided a more accurate interpretation of the penile vascular status with duplex ultrasonography. Conclusions: These results suggest that oral vardenafil can be used as an initial method for inducing penile erection when assessing erectile dysfunction with penile duplex Doppler ultrasonography in selected patients with erectile dysfunction.

만성신장질환과 연관된 남성 성기능 장애

류인욱,정우식,심봉석,강덕희 이화여자대학교 의과학연구소 2007 EMJ (Ewha medical journal) Vol.30 No.2

Objective : Chronic kidney disease(CKD) and Sexual dysfunction are important public health problems in older man as a part of life. We investigated the relationship between two groups. Method : We examined sixty-five CKD patients on glomerular filtration rate (GFR), serum creatinine (sCr), Prevalence period and causative disease. Sexual function was evaluated by International Index of Erectile Function(IIEF-5), libido(2 items), ejaculation(4 items), frequency of sex in a month and serum testosterone. A control group composed of eighteen male adults who had visited to the general medical testing center in the hospital. They didn't have any combined disease and they were similar age range to the group of the CKD. We analyzed correlations between components of the CKD and sexual function. Result : The study revealed that all sexual components of the CKD group(mean age 51.8±2.6) were significantly worse than the control group; 12.3±3.9 of IIEF-5, 5.4±1.8 of libido and 10.1±2.2 of ejaculation, 1.4±0.7times of sex in a month in the CKD group and 18.3±3.5 of IIEF-5, 7.2±2.1 of libido and 15.3±2.9 of ejaculation, 2.9±1.1 times of sex in a month in the control group. The patients whose prevalence period of CKD was over than 3 years or whose sCr was over than 2.0ng/㎖, had all sexual components worse significantly. Comparing by the causative disease of the CKD, there was no any significant difference. Analyzing by correlation, erectile function is related with serum glucose, sCr, Prevalence periods and libido is related with prevalence periods, and ejaculation is related with diabetes. Conclusion : The patients with CKD may have a sexual dysfunction that make erection, libido and ejaculation and the number of their sex seemed to decrease. Therefore we need to have more attention to their sexual function as an important part of life.

신호처리용 IC 칩 부착 서스펜션의 열 및 동특성 해석

류인욱(In-Uk Ryu),김동운(Dong- Woon Kim),박노철(No-Chol Park),박영필(Young-Pil Park) 대한기계학회 2002 대한기계학회 춘추학술대회 Vol.2002 No.5

In order to increase a write frequency in hard disk drive, suspension designers have introduced that the improvement of the write driver and read/write head. Another choice is the selection of the location of the driver IC chip. This paper is about the change of the resonant frequency of the chip-on-suspension both by moving the location and varying the mass. During operation the IC chip generates heat which causes the thermal deformation. Also the effect on variation of the head loading force resulted from the thermal stress and thermal deformation is investigated. The simulation is performed by using Ansys program which can analyze both the temperature distribution and the thermal-stress analysis.

영아에서 발생한 황색육아종성 신우신염

이하나,김규현,류인욱,한민철,정우식 대한비뇨의학회 2006 Investigative and Clinical Urology Vol.47 No.12

과민성방광증후군에서 치골상부 자기장치료의 효과

심봉석,윤하나,김규현,홍근식,류인욱 이화여자대학교 의과학연구소 2008 EMJ (Ewha medical journal) Vol.31 No.1

Objectives : Overactive bladder(OAB) is a symptom syndrome including urinary urgency with or without urinary incontinence, usually combined with frequency and nocturia. There are lots of reports concerning the first-line treatment for OAB, the treatment is still challenging. Extracorporeal magnetic innervation(ExMI) therapy have been known to be safe and effective immediately in stress urinary incontinence and OAB. The aim of this study was to assess the effect of suprapubic magnetic innervation therapy by arm-typed plate in patients with OAB. Methods : The selected subjects were 32 patients diagnosed with OAB between the periods of April to September, 2007. Mean age was 48.3±10.7 years old, and there were 10 males and 22 females patients. Voiding diary, International Prostatic Symptoms Score(IPSS), quality of life(QOL) questionnaire were evaluated as assessment of voiding symptoms. The treatment was performed for 15 minutes, 2 times a week, for 6 weeks with ExMI by arm-typed plate(BioCon-2000. M-Cube, Korea). All of the evaluations were repeated immediately and 3 months after treatment. Results : The mean urgency episodes decreased from 13.2±1.81 times to 8.7±1.95 times immediately after treatment and 9.6±2.18 times at 12 weeks after treatment(p<0.05). At 6 weeks after starting treatment, the mean frequency decreased from 5.4±1.58 times to 3.6±1.37 times(p<0.05), but the mean frequency after 6 months was 4.3±1.72 times(p>0.05). Significant improvements immediately after treatment were noted in the frequency, urgency, and QOL in IPSS, which were maintained for 3 months(p<0.05). There were improvements in mean voided volume, but these were minimal. Conclusion : The symptoms of OAB are highly prevalent and significantly affect the quality of life. Effective and prompt management of OAB should be implemented. Our datas suggested that the EXMI therapy by arm-typed plate has the favorable effect on OAB and it may be persist for at least 12 months. Further studies are needed to establish the long-term efficacy of EXMI therapy in patients with symptoms of OAB.