Human tissue-type plasminogen activator의 국소 세척 및 전신 투여가 미세혈관 혈전증에 미치는 영향

류승희,오희균 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.3

The needs of microvascular anastomosis or vessel graft to reconstruct maxillofacial tissue defect has been increased and a variety of attempts to improve the rate of patency has been achieved. Thrombolytic agents has been advocated in order to decrease the failure rate of microvascular anastomosis and to prevent the need for reoperation. Older thrombolytic agents, such as streptokinase or urokinase, have a significant side effects such as allergy, hyperthermia, systemic bleeding complications. This study was performed to evaluate the effect of local irrigation and intravenous administration of human tissue-type plasminogen activator (t-PA), which is known as effective thrombolytic agent with less systemic side effects, on patency and thrombus formation of experimental microvascular anastomoses in the traumatized femoral vein of rabbit. Nine rabbits weighing about 2㎏ were used. After exposure of both femoral veins. the veins were crushed by the jaws of smooth needle holder in order to create a thrombosis model. Transectional incision was made in the vein. The animals were then divided into 3 groups: 1) Experimental Group Ⅰ, topical irrigation of lumen with t-PA saline solution (n=6); 2) Experimental Group 2, Intravenous administration of t-PA (0.75 ㎎/㎏) via the marginal ear vein for 3 days; 3) Control Group, topical irrigation of lumen with saline solution (n=6). The veins were anastomosed utilizing microvascular technique with 10-0 Ethilon. The patency was evaluated with empty-and-refill test 30 minutes and 3 days after microanastomosis. The thrombus formation was evaluated 3 days after microanastomosis by observing the thrombus with surgical microscope. The histologic findings were also evaluated. The results were as follows: 1. Thirty minutes after microvascular anastomosis, the patency of all Experimental Groups 1 and 2 was more improved than that of Control Group. However, there was no significant difference among groups. 2. Three days after microvascular anastomosis, the patency of all Experimental Groups was much more improved than that of Control Group (p<0.05). There was no significant difference between Experiment Group 1 and Experiment Group 2. 3. Three days after microvascular anastomosis, the amount of thrombus in all Experimental Groups was much less than that of Control Group (p<0.05). 4. In histologic findings, a lot of luminal thrombus were observed around sutured area in Control Group. Few luminal thrombus was observed in all Experimental Groups. The necrotic changes were was observed in the vessel wall of all specimens. These results indicate that topical irrigation and intravenous administration of t-PA are effective measures in improving patency and preventing thrombus formation after microvascular anastomosis.

우리나라 유아영어교육의 바람직한 방향모색

류승희 대불대학교 2003 大佛大學校大學院 硏究論文集 Vol.2 No.1

The purpose of this paper is to suggest the better ways of English education for Korean preschoolers by analyzing the results obtained from the surveys focused on the actual states lf English education for preschoolers since 1980. Since 1986, there was a steadily increasing tendency of institutions per- forming early English education, and from 1997 when English became one of the regular subjects from the 3rd garde in an elementary school, there was a rapid increasing. More and more institutions will perform early English education in the future. However, there are so many problems in performing English education in kindergartens and children's houses. They include mainly the lack of qualified teachers and teaching materials suitable for Korean young children and the teachers' lack of knowledge of English teaching methods, Therefore, let me suggest the better ways to solve them. Firstly, the Ministry of Education or Korea should make a legal device to help them teach English young children in better ways. Secondly, the departments of early childhood education in universities should put the subjects related to English teaching method for Korean preschoolers in their curriculum in order to make the students qualified teachers after graduation. Thirdly, the teaching materials of English suitable for Korean preschoolers in EFL environment should be provided as much as possible. Fourthly, the teachers should provide them a comfortable atmosphere environment to do daily routine(such as saying hello to eneryone they meet, the weather talking and asking how they feel) in English everyday.

유아·놀이중심 교육과정을 위한 유아교사의 시도와 변화: 「2019 개정 누리과정」 1, 2차년도 실행을 바탕으로

류승희,이정욱 한국유아교육학회 2023 유아교육연구 Vol.43 No.1

The purpose of this study is to investigate the attempts and changes implemented by early childhood teachers over the years for the child·play-centered curriculum emphasized in the 「2019 revised Nuri curriculum」. For this study, 8 teachers working in early childhood education institutions participated from November 2020 to end of July 2021. The study results and conclusions are as follows. First, the teacher’s curriculum implementation was varied in form, depending on the contexts of institutions and individuals at work. Nevertheless, there was a common consensus in that the teachers were constantly looking back to review whether their practices were suitable for child·play-centered activities pursued by the 「2019 revised Nuri curriculum」. Second, in the first year, teachers practiced the child·play-centered curriculum in the direction of transferring initiative to children. In the second year, intentional teaching was conducted, and the balance between child-directed and teacher-directed instruction was considered. Based on these research results, it was discussed that the power of the national-level curriculum, the meaning of teacher’s curriculum implementation perspective and child·play-centered curriculum should be reestablished. 본 연구는 「2019 개정 누리과정」에서 강조하는 유아·놀이중심 교육과정을 위하여, 유아교사 들이 해를 거듭하는 가운데 어떠한 시도를 하며 변화하는지 살펴보는 데 목적이 있다. 이를 위 하여 2020년 11월 11일부터 2021년 7월 31일까지 유아교육기관에 근무하는 교사 8인과 함께 「2019 개정 누리과정」 실행에 관한 자료를 수집하였다. 연구결과는 다음과 같다. 첫째, 본 연구 에 참여한 모든 교사들은 「2019 개정 누리과정」이 국가수준 교육과정임을 의식하였고, 2년 연 속 ‘「2019 개정 누리과정」의 유아·놀이중심’을 위해 노력하는 실행으로 나타났다. 기관 및 개인 의 상황 맥락이 작용하고 있기 때문에 교사마다 교육과정 실행 자체는 다양하였지만, 자기 실 행이 「2019 개정 누리과정」이 추구하는 유아·놀이중심에 맞는지 끊임없이 돌아보는 모습은 2 년 연속 이어졌다. 둘째, 교사들은 1차년도에는 유아에게 주도권을 이양하는 방향으로 유아·놀 이중심 교육과정을 실천하였으나, 2차년도에는 의도적 교수를 하며 유아주도와 교사주도의 균 형을 고려하는 모습을 보였다. 이러한 연구결과를 바탕으로, 국가수준 교육과정이 가진 힘과 교육과정 실행 관점에 대한 해석 및 유아·놀이중심의 의미를 재정립해야 함을 논의하였다.

FRAP assay를 이용한 콩의 항산화 효과와 항산화물질과의 관련성

류승희,김선희,문갑순 한국생명과학회 2001 한국생명과학회 학술발표회 Vol.33 No.-

팩트체크 현황과 이슈에 대한 네트워크 분석 : 코로나19를 중심으로

류승희,정정주 경북대학교 사회과학연구원 2020 사회과학 담론과 정책 Vol.13 No.2

The global COVID-19 pandemic has created a brutal reality check for mankind. Organizations and media around the world are fact-checking misinformation about the coronavirus. Based on the assumption that existing oversight of fact-checking is limited among related organizations and media, this research examines the structure and characteristics of fact-checking by focusing on COVID-19 in Korea. This study analyzed 117 issues fact-checked by at least 3 media outlets or 2 media outlets along with the SNU FactCheck from a total of 547 issues fact-checked by 52 media outlets and the academic organization. The results indicated how those services in Korea fact-check misinformation related to the coronavirus pandemic in the nation. The new age of fact-checking could be interpreted as journalism adapting to the needs of its digital environment. This research suggests fact-checking as a source for comparing results with future studies. 팩트체크가 사회적 논란이 되고 있는 이슈에 대한 사실 여부를 판단하는 새로운 저널리즘 양식으로 등장하였다. 그러나 많은 매체가 팩트체크 역할을 수행하고 있음에도 불구하고 그 현황과 특성에 대한 연구가 부족했다. 본 연구는 형식적 객관주의에서 팩트체크로 전환된 현재의 저널리즘 연구의 토대가 되기 위해 코로나19 사태를 중심으로 어떠한 기관이나 매체가 팩트체크 생태계에 참여하고 있으며, 이들이 팩트체크 하는 이슈는 무엇인지 확인하고자 하였다. 또한 팩트체크를 주도하는 기관이나 매체는 누구이며, 팩트체크 이슈를 기반으로 관련 네트워크는 어떻게 구성되어 있는지를 구조적으로 분석하였다. 분석결과 학계의 SNU팩트체크를 비롯해 총 73곳의 기관이나 매체가 팩트체크 서비스를 제공하고 있었다. 코로나19와 관련해 팩트체크 이슈를 제기한 기관 및 매체는 53곳이었다. 주요 방송사, 신문사, 통신사 및 인터넷 기반의 다양한 매체가 팩트체크 관련 서비스를 제공하고 있었는데, 이는 팩트체크가 하나의 새로운 저널리즘 기반 서비스이면서, 누구나 플레이어로 ‘팩트체크’ 행위에 직접 참여할 수 있는 사업이라는 것을 보여주었다. 지금의 팩트체크 생태계에서 SNU팩트체크가 차지하는 구조적 위상과 역할이 상당했다. 기관과 매체의 팩트체크 현황과 특성 및 이슈 기반의 네트워크 구조 분석은 팩트체크 대상 유형(출처), 판정결과, 검증근거(소스) 연구 등 다양한 심층연구의 토대가 될 것이다.

유아교사 자율성에 관한 고찰: 문화역사적 활동 이론의 ‘모순’ 개념을 바탕으로

류승희 한국유아교육학회 2024 유아교육연구 Vol.44 No.6

본 연구는 유아교사 자율성에 관해 문화역사적 활동 이론의 모순 개념을 바탕으로 알아보기 위해 수행되었다. 중점 연구방법은 교사 심층면담과 교사 저널, 기관 문서 및 사진자료 분석 등이었으며, 유치원 교사 4명, 어린이집 교사 2명의 사례를 분석하였다. 연구결과는 다음과 같다. 첫째, 활동체계 내 힘의 차이에서 모순이 발생하였을 때, 교사는 기꺼이 혹은 어쩔 수 없이 교사 자율성을 제한하였으며, 긴장 속에서 저항하며 교사 자율성을 발휘하고 있는 경우도 있었다. 둘째, 국가수준 문서와 현실 간 간극에서 모순이 발생하였을 때, 교사들은 자율과 타율 사이에 교사 자율성이 있다고 보았으며 적절한 선에 맞춰 교사 자율성을 발휘하기도 하였고, 외부 활동체계의 모순을보며 교사 자율성에 관한 자신의 이해를 심화시키는 교사도 있었다. 본 연구결과를 바탕으로 교사자율성을 행위주체성 관점에서 보아야 함을 논하였다. 아울러 교사 자율성에 힘을 행사하는 활동체계와 모순에 관해 탐구할 필요가 있음을 제언하였다. This study was conducted to examine the autonomy of early childhood teachers based on the concept of contradiction in cultural-historical activity theory (CHAT). In-depth interviews, teacher journals, institutional documents, and photograph analysis were collected as data, from which the cases of four kindergarten teachers and two daycare center teachers were analyzed. The results are as follows. First, when a contradiction occurred due to the difference in power within the activity system, teachers willingly or inevitably restricted teacher autonomy, sometimes resisting and exercising it under tension. Second, when a contradiction occurred due to the gap between national-level documents and reality, teachers viewed teacher autonomy as existing between autonomy and heteronomy. The teacher autonomy was mostly exercised within an appropriate range, and some teachers deepened their understanding by observing the contradiction in the external activity system. Based on these findings, it was argued that teacher autonomy should be viewed from the perspective of agency. In addition, it was suggested that it is necessary to explore the activity system and contradiction that exert power on teacher autonomy.

맥베스의 비극성에 관한 연구

류승희 대불대학교 1998 論文集 Vol.4 No.1

Most critics focusing their criticism mainly on the heroes's character insist that the heroes' actions come from their characters. However, their criticisms are not completely reasonable statements of the cause of which Shakespeare's tragic heroes result in their tragic ends. That's why their tragedies would not happen if they were not in their particular reality--tragic reality. Their characters of the flaws of their characters can not be their entire causes, but just a part of them. Therefore, their tragic reality should also be examined as a cause of their tragic ends. From this point of view which their tragedies are resulted from the interaction of their characters and their tragic reality, Macbeth's tragedy is analyzed in this paper. In Macbeth, Macbeth has deep and strong ambition for kingship and powerful imagination. He is Duncan's cousin, a prominent general who has conquered rebels, so that he gets to subconsciously have ambition for kingship. He has powerful imagination unlike a warlike general. This characteristic plays and important role in leading him to tragic end. He has hallucinations before and after murdering Duncan and is led much more deeply into the evil world by his rich imagination although he knows the nature of his crime and its end. there are three witches and lady Macbeth in Macbeth's reality. The witches that symbolize disorder and evil externalize Macbeth's ambition latent in his inner mind by prophesying of his past, present, and futures. His ambition overpowers his reason, so his mental order gets destroyed rapidly. Bdsides, Lady Macbeth with strong evil-passion instigates Macbeth insistently and prudently, so he gets succumbed to murder Duncan. But they cause him to be a tyrant who dares to murder continually without any more hesitation in order to reduce his fear and terror. Finally he loses everything which had attained before murdering Duncan. He is entirely isolated from his world and even Lady Macbeth. Everything is meaningless to him. this is his tragic end. In conclusion, Macbeth meets his tragic end in his inner and outer conflicts caused by the interaction between his tragic reality and his character or his tragic flaws.

지역 고용시장 현황과 시사점

류승희,신유란,오준범 현대경제연구원 2021 한국경제주평 Vol.917 No.-

실내가장놀이와 실외가장놀이에서의 가작화와 의사소통전략에 관한 연구

류승희,최연,강의정 대불대학교 2004 大佛大學校大學院 硏究論文集 Vol.3 No.-

This article aims to investigate the difference of make-believe and the difference of communication strategy in indoor and outdoor pretend play. Its object is 50 5-year-old children who have been in tow kindergartens located in seoul. The results are as follows : the children who did pretend play outdoors showed higher make-believe of role, objects, actions, and situations than those who did indoors. In pretended communication strategy, the children who did outdoor pretend play showed higher cooperation and expressing feelings, but lower control and repetiton than those who did indoor pretend play. In Meta communication strategy, the children who did outdoor pretend play showed higher cooperation, however, lower control and shrink than those who did indoor pretned play.

COCAW: A Genome-wide Pattern Search System for Designing Microbial Probes

류승희,박기정,이도훈,김철민 한국유전체학회 2009 Genomics & informatics Vol.7 No.3

A few bioinformatics tools have been used to find out conserved regions as probes. We have developed a system based on a heuristic method with web interfaces to find out conserved regions against microbial genomes. The system runs in real time by using relative entropy in limited narrow regions and detecting similar regions between pair regions with local alignment. The system could be useful to find out conserved regions as genome-wide scale.