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류성윤,김해진,김성목,박성지,최연현 대한자기공명의과학회 2016 Investigative Magnetic Resonance Imaging Vol.20 No.1
We report a case of perivalvular abscess in a 66-year-old man with infectiveendocarditis, diagnosed by late gadolinium-enhanced (LGE) cardiovascular magneticresonance (CMR) imaging. No clinical features suspicious of infective endocarditiswere noted, however, transthoracic echocardiography revealed non-specific echogenicfocal wall thickening at mitral-aortic intervalvular fibrosa. Perivalvular abscess in theaortic valve was demonstrated as focal wall thickening between the anterior mitralleaflet and the non-coronary cusp of the aortic valve with peripheral enhancementand central low signal intensity on LGE CMR imaging. Other features suggestiveof infective endocarditis, such as neither vegetation nor valvular perforation werepresent. The perivalvular abscess did not grow after intensive intravenous antibioticstherapy, and the patient was discharged without surgical treatment. CMR withLGE provided an early accurate diagnosis of perivalvular abscess. The diagnosis ofperivalvular abscess using LGE CMR imaging was not previously reported in Korea.
A Case of Rosai-Dorfman Disease with Highly Elevated Serum Ferritin
류성윤,장희창,박경화,안재숙,김가언,최유덕,정숙인 대한진단검사의학회 2012 Annals of Laboratory Medicine Vol.32 No.2
Sinus histiocytosis with massive lymphadenopathy, also known as Rosai-Dorfman disease is a rare disorder characterized by proliferation of distinctive histiocytes within lymph node sinuses and lymphatics, sometimes involving extranodal sites. However, clinical suspicion is difficult and there is also a lack of useful diagnostic markers for this disorder prior to histological confirmation. High elevation of serum ferritin is known to be a useful diagnostic marker for various hematologic diseases, including hemophagocytic lymphohistiocytosis and lymphoma. Here, we report a case of fever of unknown origin that presented along with highly elevated serum ferritin (5,780 ng/mL), and was finally diagnosed as Rosai-Dorfman disease by lymph node biopsy.