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천연물로부터 NFAT (Nuclear factor of activated T cells) 전사인자에 대한 저해활성 탐색
이임선,닷, 윈디엔,채흥복,심광해,김영호 충남대학교 약학대학 의약품개발연구소 2003 藥學論文集 Vol.18 No.-
The NFAT (nuclear factor of activatied T cells) protein induces transcription of genes required for T-cell activation, including the L - 2 gene. Activation of NFAT normally plays a significant role in inducing immune response. However, excessive activation provokes immunopathological reactions including autoimmunity, transplant rejection and inflammation. Thus, one hundred of natural products were screened on the inhibitory activity against the NFAT transcription factor. Three natural products (Celtis choseniana, Acer tegmentosum, Rubus takesimensis) showed strong inhibitory activity against the NFAT transcription factor without affecting cell viability. These MeOH extracts will be successively partitioned with CHCl₃, BuOH and H₂O to isolate active compound for the development of anti-inflammatory or immunosuppressive agent with good safety.
심광해,채흥복,닷, 윈디엔,이은주,배기환,강종성,김영호 충남대학교 약학대학 의약품개발연구소 2004 藥學論文集 Vol.19 No.-
Gentianae scabrae Radix has been used in traditional medicine for the treatment of analgesic, anti-inflammatory and gastrointestinal tract diseases In order to evaluate the quality of Gentianae scabrae Radix, quantitative determination method of gentiopicroside has been developed by the HPLC method using the mobile phase of acetonitrile-water (1'9) and C_(18) column. The amount range of gentiopicroside in 20 samples was 0.97 to 5 89%
자유 시점 TV에서 시점 합성을 위한 시공간적 배경 정보 추정 기반 홀 채움 방식
김범수,응웬 띠엔 닷,홍민철,Kim, Beomsu,Nguyen, Tien-Dat,Hong, Min-cheol 한국전기전자학회 2016 전기전자학회논문지 Vol.20 No.1
본 논문에서는 자유 시점 텔레비전에서 시점 합성 영상 획득을 위해 시공간적 배경 정보 추정 기반 홀 채움 방식을 제안한다. 신뢰할 수 있는 시간적 배경 정보를 획득하기 위해 새로운 배경 코드북의 구성 및 갱신하는 과정을 수행한다. 더불어, 공간적인 국부 배경 정보 추정을 위해 홀 영역의 배경 및 전경 영역의 구별 및 갱신 과정을 수행한다. 추정된 시공간 배경 정보를 조합하여 홀 채움 과정을 수행하고, 잔여 홀 채움을 수행하기 위해 깊이 배경 정보를 이용한 우선순위 함수를 결정하여 표본 기반 인페인팅 기법을 적용한다. 실험 결과를 통해 제안 방식은 기존방식들과 비교하여 평균 0.3~0.6dB의 성능 향상이 있음을 확인하였으며, 동영상 특성 및 홀 형태에 관계없이 제안된 방식이 새로운 시점 영상을 효과적으로 합성할 수 있음을 확인할 수 있었다. This paper presents a hole-filling algorithm based on extrapolating spatial-temporal background information used in view synthesis for free-viewpoint television. A new background codebook is constructed and updated in order to extract reliable temporal background information. In addition, an estimation of spatial local background values is conducted to discriminate an adaptive boundary between the background region and the foreground region as well as to update the information about the hole region. The holes then are filled by combining the spatial background information and the temporal background information. In addition, an exemplar-based inpainting technique is used to fill the rest of holes, in which a priority function using background-depth information is defined to determine the order in which the holes are filled. The experimental results demonstrated that the proposed algorithm outperformed the other comparative methods about average 0.3-0.6 dB, and that it synthesized satisfactory views regardless of video characteristics and type of hole region.
Estimating Workers’ Locations in Industrial Sites
Quan T. Ngo(오딴콴),Dat Van Anh Duong(즈엉 반 안 닷),Doi Thi Lan(도이 티 란),Seokhoon Yoon(윤석훈) 한국통신학회 2021 한국통신학회 학술대회논문집 Vol.2021 No.11
Worker location estimation plays an important role in reducing the amount of time for rescue operations when an incident occurs, thus improves worker safety. In this paper, we address the problem of estimating the current location of a worker in the working sites, given his/her historical location records. A large-scale dataset of Wi-Fi traces is used to train and test the proposed model.