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남윤이,김진규,정해리,서준교 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.1
The inhibitory effects of lipid accumulation onethanol extract from stem bark of Japanese horse chestnut(JHC) were evaluated. Exposure to JHC extract (10-100μg/mL) for a 72 h incubation period did not alter cellviability compared to the untreated control. JHC extract,with concentrations of 25, 50, and 100 μg/mL, inhibitedlipid accumulation in 3T3-L1 adipocytes in a dosedependent manner. The expression of PPARγ and C/EBPα,important adpogenic key markers was significantly reducedwhen JHC extract was added to cells for 8 days comparedwith the untreated control group. These results suggest thatJHC extract might be a potential therapeutic agent as anatural anti-obesity material.
초기 설계단계에서의 셋 베이스 다목적 설계 최적화(제4보)
남윤의(Yoon-Eui Nahm),井上全人(Masato Inoue),石川晴雄(Haruo Ishikawa) 한국산업경영시스템학회 2012 한국산업경영시스템학회지 Vol.35 No.1
Various computer-based simulation tools such as 3D-CAD and CAE systems are widely used to design automotive body structure at the early phase of design. Designers must search the optimal solution that satisfies a number of performance requirements by using their tools and a trial-and-error approach. In the previous three reports, a set-based design approach has been proposed for achieving design flexibility and robustness while capturing designer’s preference, and its effectiveness has been illustrated with a simple side-door impact beam design problem and real vehicle side-door structure design. This report presents the development of integrated 3D-CAD and CAE system, and the applicability of our proposal for obtaining the multi-objective satisfactory design solutions by applying to an automotive front-side frame.
하이드록시아파타이트 표면 나노 구조 성장에 의한 고분자 표면의 초소수성 개질
남윤한(Yoon Han Nam),조용상(Yong Sang Cho),서경덕(Kyoung Duck Seo) 대한기계학회 2020 大韓機械學會論文集B Vol.44 No.2
초소수성 표면은 자가 세정, 방빙 등의 특성을 가지며, 산업 여러 방면에 활용될 수 있어 많은 관심을 받고 있다. 그러나 초소수성 표면 구현을 위해 제안된 기존의 방법들은 복잡한 제작 공정 및 고가의 장비가 필요하다는 한계가 있다. 따라서 본 연구에서는 의사체액(SBF: Simulated Body Fluid)을 이용하여 하이드록시아파타이트 마이크로/나노 구조를 고분자 표면 위에 성장시키고 SAM(Self-Assembled Monolayer) 코팅을 함으로써 손쉽게 초소수성 표면을 제작하였다. 제작된 초소수성 표면의 접촉각은 163.3±2.7°로 측정되었다. 더 나아가 마스킹 테이프를 이용하여 초소수성 표면을 다양한 형상으로 선택적으로 패터닝 할 수 있음을 확인하였으며, 제작된 초소수성 표면의 자가 세정 특성을 보임을 검증하였다. Superhydrophobic surfaces have attracted research interest owing to their self-cleaning characteristics, antiicing properties, etc. However, conventional fabrication methods for these surfaces still require complex processes and special facilities. Therefore, in this study, we propose a facile and cost-effective fabrication method for superhydrophobic surfaces using simulated body fluid (SBF). A PMMA (poly (methyl methacrylate)) substrate with a hydroxyl group is initially immersed in the SBF. Hydroxyapatite with micro/nanostructure is then crystallized on the substrate. Finally, a self-assembled monolayer (SAM) coating is prepared to introduce superhydrophobicity. After the coating process, the contact angle of the fabricated substrate is measured as 163.3 ± 2.7°. We also demonstrate that hydroxyapatite with a micro/nanostructure can be patterned with various shapes by using masking tape. In addition, the self-cleaning effect of the fabricated surface is observed.