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      • KCI등재후보
      • KCI등재

        라벤더 에탄올 추출물이 ${\alpha}$-MSH 유도 멜라닌 생성에 미치는 효과

        김호민,장영미,한규수,문대원,문연자,우원홍,Kim, Ho-Min,Jang, Yeong-Mi,Han, Kyu-Soo,Moon, Dea-Won,Mun, Yeun-Ja,Woo, Won-Hong 대한동의생리학회 2008 동의생리병리학회지 Vol.22 No.6

        Down-regulation of melanin synthesis is required for recovery of pigmentary disorders and it is well known that ${\alpha}$-MSH induced melanin synthesis and dendrite outgrowth on melanocytes. This study was conducted to evaluate the depigmenting properties of ethanol extract from a Lavandula vera. The ethanol extract from Lavandula vera inhibited melanin contents and tyrosinase activity in a dose-dependent manner, compared with untreated group. Treatment of the ethanol extract of Lavandula vera effectively suppressed the ${\alpha}$-MSH-stimulated melanin formation, tyrosinase activity and dendrite outgrowth. Moreover, the ${\alpha}$-MSH-induced mRNA expression of tyrosinase was significantly attenuated by Lavandula vera treatment. These results suggest that Lavandula vera exerts its depigmenting effects through the suppression of tyrosinase and cytoplasmic dendricity. And it may be a potent depigmetation agent in hyperpigmentation condition. 본 논문은 라벤더 에탄올 추출물이 ${\alpha}$-MSH 유도 멜라닌 생성에 미치는 효과에 관한 것으로 라벤더 추출물이 미백효과에 미치는 연구를 중심으로 한다. 라벤더 에탄올 추출물은 복용 의존적으로 멜라닌 함량과 티로시나아제 활성을 억제했다. 라벤더 에탄올 추출물 처치는 ${\alpha}$-MSH로 촉진된 멜라닌 형성, 티로시나아제 활성, 수상돌기 성장을 효과적으로 억제했고, 라벤더 처치에 의해${\alpha}$-MSH로 유도된 티로시나아제의 mRNA 발현이 유의미하게 감소되었다. 본 연구를 통해 라벤더 추출물이 미백효과가 있음을 알 수 있었으며, 따라서 라벤더가 색소과다침착증에 미백제로 사용될 가능성이 있다는 내용이다.

      • KCI등재

        대구 의료관광 브랜드 이미지 평가에 관한 연구

        김호민 대한관광경영학회 2011 觀光硏究 Vol.26 No.1

        Medical tourism has been regarded as an ideal strategic industry in an area where little natural resources were inherited and lagged behind in its development, as medical tourism has drawn attentions and been a focal point in discussion to promote local tourism through diverse program related to healthcare. Rewarded with a high-tech medical compound industry project recently, Daegu city needs to establish a distinctive brand image which supports its slogan of Medi-City with consistency and continuity. Therefor it is the aim of this study to come up with effective measurements in evaluating Daegu city's brand image in medical tourism. 의료관광은 전 세계인의 주요 관심사인 건강관리에 대한 다양한 프로그램 운영을 통해 관광의 활성화를 가져올 수 있다는 점에서 많은 주목을 받고 있으며, 지역개발 측면에서도 다양한 인적 자원을 필요로 하기 때문에 부존자원이 빈약하고, 낙후된 지역의 개발에 가장 적합한 전략산업으로서 각광을 받고 있다. 대구광역시는 R&D 특구지정과 함께 ‘메디시티’를 표방하는 대구시의 슬로건에 걸맞은 프로젝트를 지속적으로, 일관성 있게 추진하기 위해서 메디시티와 관련해 브랜드 이미지를 구성하는 요소의 중요도를 측정함으로써, 기존의 전통적인 대구시의 브랜드 이미지에 관한 연구가 보여주지 못했던 대구시의 브랜드 이미지 평가시에 중요한 요소를 도출하고 도출된 항목의 우선순위를 AHP를 활용하여 분석함으로써 메디시티의 브랜드 이미지에 효과적인 시사점을 제공할 목적으로 본연구의 의의가 있다.

      • KCI등재

        淸熱消毒飮이 實驗的 炎症 및 血栓症에 미치는 影響

        김호민 대한동의병리학회 1995 동의생리병리학회지 Vol.9 No.2

        연구배경 : 切斷外 특별한 治療法이 없는 脫疽에 對한 韓醫學的 治療가 未治한 실정이다. 血液의 血栓形成과 炎症誘發로 인한 병리적 변화가 誘發하는 脫疽의 치료에 瘀血의 치료법 등을 이용하는 것은 타당한 것이라 사료되어 본 연구를 시작함. 연구방법 : 이에 저자는 發熱, 浮腫, 疼痛, 發赤을 동반한 癰疽에 쓰이는 淸熱消毒飯이 炎症 및 血栓에도 有效하리라 思料되어 본 실험을 행하였으며, 淸熱消毒飯의 抗炎證 作用, 血管系에 미치는 效果, 抗血栓作用, 鎭通效果를 觀察하였다. 결과 : carrageenin으로 誘發한 浮腫은 CSY II, III群에서 有意性있는 抑制效果가 있었고, CMC-pouch에 의한 蛋白質 渗出은 CSY II, III群에서 有意性 있는 減少를 보였으나 aspirin藥物 對照群보다는 微弱하였다. Ringer液의 點滴數는 檢液의 量에 따라 濃度 依存的으로 增加하였고, norepinephrin으로 誘導한 血管收縮은 濃度에 따라 漸進的으로 緩和되었다. 抗血栓效果는 肺性血栓性 塞栓症에서의 死亡率 減少, 血小析 凝集 抑制, 血漿 抗트롬빈 活性으로 確認할 수 있었다. writhing syndrome, paw licking time, escape time을 測定한 結果, 一定한 鎭痛效果를 確認할 수 있었다. 결론 : 淸熱消毒飯이 炎症 및 血栓에 有效하였으나 차후 藥物의 가장 效果的인 濃度는 此後硏究가 必要할 것으로 思慮된다. This study wal designed to elucidate the antiinflammatory, cardiovascular, antithrmbotic, and analgesic effect of CheongyealSodog-Yeum. The antiinflammatory, effects was measured by the method of carrageenin induced edema, protein leakage test using CMC-pouch, and the effect of CheongyealSodogYeum on the cardiovascular system was observed by the change of flow rate of Ringer solution in the vascular system in the ear of rabbit, and the contraction and dilatation of rat tail artery. Death rate, platelet aggregation, plasma coagulation activity, anti-thrombin activity was observed for the measurement of the antithrombin activity was observed for the measurement of the measurement of the antithrombotic activity was observed for the measurement of the antithrombotic effect of CheongyealSodoYeum, and the analgesic effect was measured by the acetic acid method and hot plate method. The result was as follows: 1. After 2 or 3hour of CheongyealSodogYeum administration, carrageenin induced edema and CMC-pouch protein leakage was significantly decreased. 2. The droplet of Ringer solution increased according to the increase of concentration of CheongyealSodoYeum extract, and the vasoconstriction desreased dependantly to the concentration of CheongyealSodogYeum extract. 3. The antighrombotic effect of CheongyealSodogYeum was observer by the decrease of death rate, the inhibition of platelet aggregation, and the increase of antithrombin activity. 4. The slight anagesic effect of CheongyealSodogYeum extract was confirmed by the observation of writhing syndrome, paw licking time, and escape time.

      • KCI등재후보

        Computation of the Current Limiting Behavior of BSCCO-2212 High-Temperature Superconducting Tube with Shunt Coils

        김호민,심정욱,현옥배,박권배,이방욱,오일성 한국초전도.저온공학회 2006 한국초전도저온공학회논문지 Vol.8 No.4

        This paper deals with the computation of the current limiting behavior of high-temperature supercon –ducting (HTS) modules for the superconducting fault current limiter (SFCL). The SFCL module consists of a monofilar type BSCCO -2212 tube and a shunt coil made of copper or brass. The shunt coil is connected to the monofilar superconducting tube in parallel. Through analysis of the quench behavior of the monofilar component with shunt coils, it is achieved to drive an equivalent circuit equation from the experimental circuit structure. In order to analyze the quench behavior of the SFCL module, we derived a partial differential equation technique. Inductance of the monofilar component and the impedance of the shunt coil are calculated by Bio-Savart and Ohm’s formula, respectively. We computed the quench behavior using the calculated values, and compared the results with experimental results for the quench characteristics of a component. The results of computation and test agreed well each other, and it was concluded that the analytic result could be applied effectively to design of the distribution-level SFCL system.

      • 골프연습장에 참가하는 기혼여성의 운동몰입경험과 가정생활만족의 관계

        김호민,은식 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

        The purpose of this study is to examine closely between the excercise flow experience of married women participate in golf ranges and family life satisfaction. To get the best result of this study, subjects of this study were sampled 480 married women by the random sampling method. The result analyze used in this study for the data analysis is through correlation analyze and multiple regression analysis. Based upon the purpose of this study and research method, the final conclusion were warranted as below: First, there is significant relationship between the excercise flow experience of married women participate in golf ranges and household economic satisfaction Secondly, there is significant relationship between the excercise flow experience of married women participate in golf ranges and mutual satisfaction among family members. Thirdly, there is significant relationship between the excercise flow experience of married women participate in golf ranges and household labor satisfaction. Fourthly, there is significant relationship between the excercise flow experience of married women participate in golf ranges and mutual satisfaction married couple. Fifthly, there is significant relationship between the excercise flow experience of married women participate in golf ranges overall life satisfaction.

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