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      • SCOPUSKCI등재

        Ramsay Hunt 증후군에 관한 임상적 고찰

        민성욱 ( Seong Uk Min ),이갑석 ( Kap Sok Li ),원종현 ( Chong Hyun Won ),조소연 ( So Yun Cho ),허창훈 ( Chang Hun Huh ),김범준 ( Beom Joon Kim ),김명남 ( Myeung Nam Kim ),김성은 ( Sung Eun Kim ),김찬웅 ( Chan Woong Kim ),박하나 ( H 대한피부과학회 2007 대한피부과학회지 Vol.45 No.11

        Background: Ramsay Hunt syndrome (herpes zoster oticus) is characterized by vesicles on the pinna, otalgia, facial nerve palsy and sensorineural hearing loss. It is not such a common dermatological disease like herpes zoster. However, reactivation of the latent varicella zoster virus causes facial palsy and therapeutic onset is one of the prognostic factors in Ramsay Hunt syndrome. Objective: The aim of this study was to elucidate the epidemiology, the clinical characteristics of Ramsay Hunt syndrome and prognosis according to therapeutic ways. Methods: The 84 cases diagnosed as Ramsay Hunt syndrome from January 2000 to July 2007 were assessed in regard to age, sex, clinical characteristics, electromyography (EMG) results, onset of neurological recovery according to medication and onset of rehabilitation therapy by review of medical records. Results: Ramsay Hunt syndrome consisted 4.7% (84 cases of 1787) of total herpes zoster patients. The ratio of male to female patients was 37:47. Frequency was slightly higher in female patients. The mean age was 62±14.7 and the age distribution was in the range of 26∼87 years. The most common clinical appearance was vesicular eruptions and facical nerve palsy including change in nasolabial fold and location of the lip (73.8%), followed by vesicular eruptions and vestibulocochlear symptoms like tinnitus and vertigo (16.7%), facial nerve palsy and vestibulocochlear symptoms appearing together (9.5%). EMG showed abnormal results in 67.9%. More than one kind of abnormality was commonly observed. The most common abnormal EMG result was fibrillation potential (42.2%), followed by positive sharp wave (31.3%), polyphasia (10.8%), high frequency discharge (8.4%), increased insertional activity (4.8%) and fasciculation (2.5%). There was no significant difference in onset of neurological recovery between acyclovir injections and oral famciclovir or valaciclovir treatment. The patients who had received physical therapy a week after the symptoms had developed, had a faster onset of recovery (2.8 week Vs 4.1 week, p<0.05). Conclusion: This study suggests that antiviral agents of a different kind may not affect recovery onset and earlier rehabilitation therapy seems to be effective in neurological recovery in Ramsay Hunt syndrome. (Korean J Dermatol 2007;45(11):1121∼1126)

      • KCI등재

        두부 손상이 없는 골절 환자에서 혈중 S100B 단백질의 분석

        박태웅 ( Tae Woong Park ),이동훈 ( Dong Hoon Lee ),이상진 ( Sang Jin Lee ),김성은 ( Sung Eun Kim ),김찬웅 ( Chang Woong Kim ) 대한외상학회 2009 大韓外傷學會誌 Vol.22 No.2

        Purpose: There is an increasing amount of evidence that S100B could function as a marker of brain damage. However, the cerebral specificity of S100B has been questioned, so the extracerebral sources of S100B have been paid attention. We performed this investigation to show serum S100B levels after extracranial fracture in patients without current head injury and without prior neurological disease. Methods: At the emergency department, we obtained the blood samples within 6 hours from trauma patients hospitalized with extracranial fractures. S100B levels were compared between one fracture and more than two fractures, and analyzed according to the presence of soft tissue damage. Results: Patients with one fracture and those with more than two fractures did not differ by age (mean, 54.70 vs. 47.03, p=0.130), and there was no significant difference in the male-to-female ratio(33:32 vs. 21:12, p=0.226). In patients with one fracture, the mean value of S-100B was 0.56 μg/L (95% CI: 0.35-0.77) whereas in those with more than two fractures, the corresponding value was 1.09 μg/L (95% CI: 0.46-1.7, p=0.048). The S100B level of patients with soft tissue damage(1.32±0.38) was higher than that of patients without soft tissue damage(0.81±0.21), whether one fracture or more than two fractures(p=0.049). Conclusion: We present here that S100B levels were raised in 77% of patients with extracranial fractures without cerebral injury who were hospitalized from the emergency room and that the presence of soft tissue damage contributed to the increased S100B rather than the size of the fractured bone size or the number of fracturest. Thus, this study suggests that soft tissue injury may be considered as an important extracerebral source of S100B. (J Korean Soc Traumatol 2009;22:123-7)

      • KCI등재

        학생들에 대한 심폐소생술 수업방식의 비교: CPR Anytime(R)과 Little Anne(R)

        정성필 ( Sung Pil Chung ),조준호 ( Jun Ho Cho ),박유석 ( Yoo Seok Park ),김의중 ( Eui Chung Kim ),김찬웅 ( Chan Woong Kim ),이경룡 ( Kyeong Ryong Lee ),이미진 ( Mi Jin Lee ),임훈 ( Hoon Lim ),장문준 ( Wen Joen Chang ),이진희 ( Ji 대한응급의학회 2008 대한응급의학회지 Vol.19 No.6

        Purpose: We compared the effectiveness of CPR Anytime(R) and Little Anne(R) for instructing schoolchildren in CPR. Methods: We gave CPR instructions to 774 school children (24 classes) from the fifth to the eighth grade in 12 schools. We randomly selected two classes of the same grade from each school. Each class was given two hours of CPR instruction using either the Korean version of CPR Anytime(R) or Little Anne(R). The number of CPR Anytime(R) per student was 1:1 and Little Anne(R) was 1:6. The lesson consisted of didactic lecture, skill practice, and skill test. We compared the skill performance of students according to the instruction method. Results: Three hundred ninety-seven (51%) students were taught using CPR Anytime(R) and 377 (49%) with Little Anne(R). There was no difference in the compression depth, hand position, adequacy of chest recoil, volume of ventilation, self-confidence, and willingness to do CPR between the two instructional methods. The average compression depth was less than 40~50 mm. Elementary school students showed more confidence and willingness to do CPR than middle school students. Conclusion: There was no difference in CPR skill performance after instruction using either Anytime CPR(R) or Little Anne.

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