우리나라 해외취업선사의 발전방안

김재봉,박용섭,이태우 ( Jae Bong Kim,Yong Sub Park,Tae Woo Lee ) 한국해운물류학회(구 한국해운학회) 1991 해운물류연구 Vol.13 No.-

지진방재연구센터 소개 및 실험사례

김재봉,정진환,Kim, Jae-Bong,Jeong, Jin-Hwan 한국전산구조공학회 2017 전산구조공학 Vol.30 No.2

특수건물 결정과 보상에 대한 보험가액

김재봉,Kim, Jae-Bong 한국화재보험협회 1977 防災와 保險 Vol.8 No.-

산업용 로봇의 동작을 고려한 케이블 동응력 해석에 관한 연구

김재봉(Jae Bong Kim),김진규(Jin Kyu Kim),강대선(Dae Sun Kang),최웅섭(Woong Sub Choi),김문영(Moon Young Kim),이상범(Sang Beom Lee),임홍재(Hong Jae Yim) 대한기계학회 2014 대한기계학회 춘추학술대회 Vol.2014 No.4-2

흰쥐 가슴샘 재생과정에서 CD70의 발현 특성

김성민(Sung-Min Kim),김미나(Mi-Na Kim),이희우(Hee-Woo Lee),김봉선(Bong-Seon Kim),김재봉(Jae-Bong Kim),윤 식(Sik Yoon) 대한해부학회 2006 Anatomy & Cell Biology Vol.39 No.6

CD70은 TNF superfamily에 속하는 제2형 막당단백질로써 주로 큰포식세포, 활성화된 T 세포 그리고 B 세포에서 발현된다. CD70은 T 및 B 세포와 NK 세포에서 주로 발현되는 TNF receptor superfamily에 속하는 CD27과 결합함으로써 면역반응 동안에 림프구의 증식, 분화, 성숙 그리고 이동을 조절한다. 본 연구에서는 흰쥐에 cyclophosphamide (CY)를 투여하여 가슴샘의 급성 퇴축을 유발시킨 후, 가슴샘 재생과정 동안에 면역조직화학, 이중면역형광조직화학 및 역전사 중합효소 연쇄반응법을 이용하여 CD70의 발현 특성을 관찰하였다. 역전사 중합효소 연쇄반응 분석 결과, 가슴샘속질수지상세포주, DC2.4 세포주 및 RAW264.7 세포주에서 CD70의 발현을 확인하였다. 면역조직화학염색 결과, 정상 및 재생중의 흰쥐 가슴샘에서는 CD70이 큰 포식세포에서 발현되었고, 이들은 주로 가슴샘겉질에 분포하였을 뿐만 아니라 가슴샘 재생과정 동안 CD70 양성반응 세포들의 수와 크기가 현저하게 증가하였다. 또한 재생중의 가슴샘으로부터 분리한 가슴샘세포와 가슴샘 바탕질세포에서 CD70 mRNA 발현이 정상 대조군에 비해 증가하는 것을 확인하였다. 따라서 본 연구의 결과는 가슴샘 재생과정 동안 CD70이 그 수용체인 CD27을 통해 가슴샘 재생에 중요한 역할을 수행할 것이라는 사실을 시사해준다 The thymus is the central lymphoid organ for development of bone marrow-derived precursor cells into mature T-cells. The thymic stroma provides the specialized microenvironment for the proliferation, differentiation, and maturation of the immature T-cells, thymocytes. The CD27 is a tumor necrosis factor (TNF) receptor family member whose expression is limited to cells of the lymphoid lineage. CD70, the ligand of CD27, is a TNF related trans-membrane protein induced upon activation on T and B cells, dendritic cells and macrophages. CD70/CD27 interaction plays a key role in T dependent B cell responses and is responsible for plasma cell differentiation. This study was performed to investigate the expression of CD70 during regeneration following acute involution induced by cyclophosphamide (CY) in the rat thymus using RT-PCR analysis and single and double immunohistochemistry. The results from RT-PCR analysis showed that CD70 is expressed in mouse thymic medullary interdigitating (IDC)-like cells (MDC), DC2.4 and Raw264.7 but not expressed in the mouse thymic epithelial cells (subcapsular/cortex epithelial cells, cortical epithelial cells and medullary epithelial cells). Interestingly, upregulation of CD70 expression was observed in the thymic stromal cells and thymocytes isolated from rat thymus during thymus regeneration. Furthermore, immunohistochemistry demonstrated that CD70 was mainly expressed in the ED1 positive macrophages predominantly in the thymic cortex both in the normal thymus and during thymus regeneration. In line with the data obtained by biochemical analysis, CD70 immunoreactive macrophages is increased both in number and in size during thymus regeneration. Thus, the results of the present study suggest that CD70 expressed on the thymic macrophages could play a role in the development of new T cells to replace T cells damaged by cyclophosphamide treatment during thymus regeneration.

파킨슨병 모델 동물에서 GDNF 아데노바이러스 벡터를 이용한 유전자치료

성기한(Ki-Han Sung),윤인규(In-Gyu Yoon),정현실(Hyun-Sil Jung),김을선(Eul-Seon Kim),김현주(Hyun-Joo Kim),김양호(Yang-Ho Kim),윤 식(Sik Yoon),김봉선(Bong-Seon Kim),김재봉(Jae-Bong Kim),백선용(Sun-Yong Baek) 대한해부학회 2002 Anatomy & Cell Biology Vol.35 No.6

6-OHDA를 이용하여 실험적으로 유발한 파킨슨병 모델 동물을 대상으로 유전자 치료 목적으로 GDNF 유전자를 포함 하는 아데노바이러스 벡터(Ad-GDNF)를 주사하여 행동 변화와 줄무늬체와 흑색질의 tyrosine hydroxylase (TH) 면역반응양성의 도파민성 세포의 형태학적 변화를 연구하였다. 성숙한 수컷 Sprague-Dawley계 흰쥐의 줄무늬체에 6-OHDA를 주사하고, 1주 후에 apomorphine에 의한 회전 운동 양상 을 측정하여 분당 7회 이상 회전하는 동물은 파킨슨병 모델 동물에 해당하는 것으로 하였다. 이들 동물의 줄무늬체에 Ad-GDNF를 주사하고 1주 후에 apomorphine에 의한 행동 양상을 다시 측정하고, 이어서 심장 관류고정을 실시하여 형태 학적 변화를 관찰하였다. Ad-GDNF 대신에 LacZ 유전자를 포함하는 아데노바이러스 벡터(Ad-LacZ)를 주사한 것을 대조 군으로 이용하였다. 1. 파킨슨병 모델 동물의 줄무늬체에 Ad-GDNF를 주사한 동물에서 apomorphine에 의한 회전 운동 수가 유의하게 감소 하였다. 그러나 Ad-LacZ를 주사한 대조군에서는 회전 운동 수의 변화를 관찰할 수 없었다. 2. 회전 운동 수가 감소한 동물의 줄무늬체에 존재하는 TH 면역반응 양성의 축삭 종말은 대조군의 75% 수준으로 Ad- LacZ를 주사한 37%에 비하여 현저히 증가하여 TH 면역반응 양성 축삭종말의 퇴행성 변화가 방지되었다. 3. 흑색질의 TH 면역반응 양성 신경세포의 수는 Ad-GDNF를 주사한 군에서는 대조군의 82% 수준으로 Ad-LacZ를 주사한 군의 60% 수준에 비하여 유의하게 증가되어 있어서 6-OHDA에 의한 신경세포의 사멸이 방지되는 것을 알 수 있었다. 이상의 결과로 미루어 파킨슨병 모델 흰쥐의 줄무늬체에 Ad-GDNF를 한차례 주사하여 1주 후에 줄무늬체와 흑색질의 도파민성 세포의 사멸이 방지되는 것을 확인하였다. A recombinant adenoviral vector encoding human GDNF gene (Ad-GDNF) was developed to investigate the effect of GDNF gene in 6-OHDA-induced Parkinson’s disease rat. The changes of rotatory behavior and density of THimmunoreactive axon terminals and number of cell bodies were observed by the GDNF expression. Adult male Sprague-Dawley rats were used. Parkinson’s disease (PD) rat models were prepared by the injection of 6-OHDA into the striatum. After 1 week, the animals showing apomorphine-induced rotatory behavior above 7 turns/ min were defined as PD rat model. Ad-GDNF was injected into the striatum of animal model and tested the apomorphine- induced rotatory behavior at 1 week after injection. These animals were perfused with Zamboni fixative to investigate the morphological changes after rotatory behavior test. Instead of Ad-GDNF, Ad-LacZ injected PD rats were used as a control. The following results are obtained: 1. The apomorphine-induced rotational behavior was significantly reduced by the treatment of PD rat by the injection of Ad-GDNF. The Ad-LacZ injected PD rat showed no change in rotatory behavior. 2. The density of TH-ir axon terminals in the striatum was significantly increased by the Ad-GDNF injection (75% of normal side), but there was no change in the density by the Ad-LacZ injection (37% of normal side) compared to 6-OHDA lesioned striatum. This means the Ad-GDNF injection prevented the degenerative change of TH-ir axon terminals in the stritum of the PD rat. 3. The number of TH-ir cell body was significantly recovered by the Ad-GDNF (82% of normal side), but there was not recovered by the Ad-LacZ injection (60% of normal side) compared to 6-OHDA lesion. This means the retrogradely transported Ad-GDNF induced the TH expression in the dopaminergic neurons of the substantia nigra. Gene therapy with Ad-GDNF prevented the degeneration of dopaminergic neurons and axon terminals in the 6- OHDA-induced PD rat.

논문 : 소년경찰과 다이버전

김재봉 ( Jae Bong Kim ) 한국형사정책학회 2005 刑事政策 Vol.17 No.1

불법 집회시위현장에서 사진,비디오 촬영의 형사소송법적 근거와 한계

김재봉 ( Jae Bong Kim ) 한국경찰법학회 2008 경찰법연구 Vol.6 No.2

In letzter Zeit wird Lichtbilder oder Bildaufzeinungen von Staatsanwaltschaft oder Pozeibeamte immer wichtig, weil sie in dem Erimittlungsverfahren eine große Rolle spielen. Das Fotographieren ist als eine notwendige Ermittungsmethode vor allem am Tatort oder unmittelbar nach der rechtwidrigen Versammlung oder Demonstation angesehen. Jedoch kann man eine Moglichkeit nicht ausschlißen, wichtige Grundrechte zB. Privacy, Personlichkeitsrecte, Versammlungsfeiheit usw. dadurch verletzt zu werden. Je mehr technische Mittel entwickelt werden, desto wird die Gefahrlichket großer. Unglulicklich kann man die Vorschriften dauber in den koreanichen Gesetzen nicht finden. Deswegen mussten die Losungen theoretisch erforscht werden, Bild- oder Videoaufzeinungen zutreffend zu regeln. Hier konnte mehrere Kriterien eingefuhrt werden. Zuerst sollte die Herstellung der Lichtbilder in der nicht offentlichen Sphare fur Zwangsmaßnahme gehalten werden, sind Gesetzlichkeitsprinzip und Richtersanordnung geboten. Die Staatsanwaltschaft und Polizeibeamten konnen im Prinzip frei in den offentlichen Orten Bider aufhnehmen. Wenn die Bilder doch langfristig und fortdauernd aufgenommen werden, werden die Grundrechte auch in dem offentlichen Gebiet eingegriffen, deshalb sind Gesetzlichkeitsprinzip und Richtersanordnung erforderlich. Wenn die Bildauzeichnungen auch als feie Maßnahme betrachtet werden, sollten Verhaltnismaßigkeit und Ubermaßverbot befolgen werden. Es ist oben de lege lata dargestellt. Doch ist es erwunscht, die ausdruchkliche Vorschriften in der Strafprozessordung einzufuhren.

우범자 관찰보호제도의 문제점과 개선방안

김재봉(Jae Bong Kim) 한국형사정책학회 1998 刑事政策 Vol.10 No.-

N/A

디지털 증거의 증거능력요건으로서 동일성과 그 확보방법

김재봉 ( Jae Bong Kim ) 한양대학교 법학연구소 2014 법학논총 Vol.31 No.1

In the age of digital revolution, so called third industrial revolution. we enjoy the convenience of digital devices such as computers, smart phones, etc. Digital technology is inseperable from our everyday life any more. The proportion of digital information from all information in the world is estimated at over 95%. With this trends, digital information plays an important role to prove criminal facts and digital evidence which is presented to the court in the criminal proceedings has increased rapidly. Therefore, digital forensic continues to increase its importance. Nowadays criminal investigaion is impossible without computer forensic or digital forensic. However, legal or institutional bases for digital evidence is not sufficient. So it is questionable whether we are ready for dealing with digital evidence in the criminal procedure. So far, most researches have been concentrated on the procedural legality of search and seizure of digital evidence. The issue of identification or integrity has been relatively less handled. Digital evidence is easy to forge, falsify, modify and delete, so it is hard to preserve the chain of custody. This is the reason why we should have interests in the integrity of digital evidence. This paper deals with the admissibility of digital evidence, inter alia, identification or integrity as the requirement of admissibility of evidence. It consists of 4 chapters. The main ideas lie in chapter 2 and chapter 3. Chapter 2 deals with the identification or integrity of digital evidence as the requirement of evidence. At first, the concept and characteristics of digital evidence are laid out and the conditions of admissibility of digital evidence are looked into. Next, the integrity as the requirement of admissibility of evidence are discussed in detail. Chapter 3 handles the methods to ensure the integrity of digital evidence. It is studied what kind of measures and process are to be taken for securing of identification or integrity of digital evidence, while law enforcement agencies such as police officers or prosecutors collect and preserve digital evidence. Subsequently, which way or process is desirable to confirm the identification. Several ways e.g. Manipulation Detection Code(MDC), Message Authentication Code(MAC), Public Key Infrastructure(PKI), and so forth have been suggested for securing the integrity of digital evidence. Each method has strengths and weaknesses. This paper proposes the combination of them. In this paper the issue of identification of digital evidence is dealt with roughly. To prove criminal facts truthfully and efficiently, the more studies on identification or integrity of digital should be made consistently.