외부 방사소음 측정을 이용한 소음원의 근접장 예측

김봉기(Bong-Ki Kim),김중희(Joong-Hee Kim),이정권(Jeong-Guon Ih) 한국자동차공학회 1997 한국자동차공학회 학술강연초록집 Vol.- No.-

한국형 자궁경부 촬영진 ( New Cervicography ) , 세포검사 그리고 HPV-DNA 검사를 이용한 새로운 자궁경부암 검진 모델 ( Model ) 개발

김승조(SJ Kim),박찬규(CK Park),이효표(HP Lee),남궁성은(SE Namkoong),강순범(SB Kang),서호석(HS Saw),이재관(JK Lee),김수녕(SN Kim),김재원(JW Kim),배석년(SN Bae),김찬주(CJ Kim),이근호(KH Lee),이선영(SY Lee),김인호(IH Kim),이찬(C Lee),이정노(JN Lee) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.5

Objective : The false negative rate of conventional cytology is reported to range from 18 to 45%. It is necessary to develop more effective screening strategies that would ideally be more accurate than conventional cytology. This study is designed to investigate the potential of conventional cytology, cervicography, HPV-DNA testing and their combinations as primary screening techniques for cervical neoplasia. The purpose of this project is to develop the models and guidelines for screening tools of cervical cancer of the uterus by evaluating sensitivity, specificity and cost-effectiveness of all the screening methods. Study design : We conducted a screening of random sample of women who visited the department of OB-Gyn. of five different major university hospitals such as Catholic University Hospital, Korea University Hospital, Seoul National University Hospital, Yeonsei University Hospital and Pochon CHA University Bundang CHA Hospital, from May 1, 1996 to April 30, 1999. In a cohort women with an age range of 20 to 70 who underwent routine cytologic screening at Catholic University, Hospital Bundang CHA General Hospital and local clinics from April 1, 1996 to Decomber 31, 2000. cervicography (n=417,125) and testing for HPV-DNA (n=1,347) by the hybrid capture assay were studied for the ability of the cervical cancer screeuing. A new cervicography system with Kim's classification which was developed by Prof. Kim Seung Jo as an adjunctive method for the cervical cancer screening was applied in this cohort study. And then, accuracy, effectivencess, cost-effectiveness of the single or combined screening method were analysed. Result : Sensitivity and specificity of Pap smear were ranged from 55.6% to 83.1% and 72.8% to 88.3% respectively. The combination of Pap smear and cervicography had sensitivity from 89.7% to 98.6%, specificity from 68.2% to 93.2%. With combination of Pap smear, HPV DNA test and cervicography, sensitivity became also highest accuracy among all screening methods from 92.8% to 98.8%. Considering medical charges for diagnosis and social cost occurred by false positive and false negative results, the most cost-effective diagnostic modality was thought to be the combination of Pap smear and cervicography(91,433 won). In patients who were diagnosed as LSIL, colposcopic examination confirmed progression to high grade intraepithelial lesion(HSIL) in 10.7% patients, persistence of LSIL in 55% patients during the 3 year follow-up period. Accuracy of the screening for cervical cancer and CIN can significantly be improved by cytology with new cervicography rather than cytology alone. We concluded that cervicography can be important adjunctive tests for cervical cytology, improving the effectiveness of cervical screening by allowing a more sensitive detection of cervical neoplasia.

제왕절개 자궁적출술에 대한 임상적 고찰

박형진(HJ Park),김일한(IH Kim),김남식(NS Kim),차동수(DS Cha),김명철(MC Kim),한상원(SW Han),한혁동(HD Han) 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.9

This study analyzed the outcome of 26 cases of cesarean hysterectomy performed at Wonju Christian Hospital, College of medicine, Yonsei university during 15 years from January, 1982 to May, 1996. There were 27,602 deliveries during this period. Cesarean hysterectomy was performed in 11 of 10,373 cesarean section(0.11 %) and in 15 of 17,229 vaginal deliveries(0.09 %). The age of pati- ents varied from 20 to 48. Indications for emergency cesarean hysterectomy were uterine atony (46.2 %), uterine rupture(26.9 %), and placenta accreta(19.2 %). The relative risk of emergency hysterectomy was 1.22(95 % confidence interval 0.56 to 2.65) for cesarean deliveries, 1.91(95 % confidence interval 0.73 to 4.98) for prior cesarean deliveries and 20.56(95 % confidence interval 10.85 to 38.95) for placenta previa. The patients who had cesarean hysterectomy received from 750 ml to 11,500 ml of blood transfusion with a mean of 3,500 ml. No significant differences in length of operating time, amount of blood loss and postoperative complications were found between total abdominal hysterectomy and subtotal abdominal hyste- rectomy. In about 1/2 of total patients (46.2 %), there were no operative complications. Maternal death was found in 1 case. Hemorrhage still remains main cause of maternal mortality, the decision of hysterectomy must be conjunction with maternal life saving and free from various dangerous sequalae. So in this study, clinical evaluation for cesarean hysterectomy and an attempt to identify risk factor that might pridict those patients likely to require emergency hysterectomy was made.

최대운동시의 산소섭취량 , 심박수 및 산소맥

김태석(Tae Sug Kim),김이근(Ih Geun Kim),김지희(Chi Hui Kim),김채기(Chae Gi Kim),최정윤(Jung Yoon Choe),장성국(Sung Gug Chang),이봉열(Bong Ryeol Lee),채성철(Sung Chul Choi),전재은(Jae Eun Jun),정태훈(Tae Hoon Jung),박의현(Wee Hyun Par 대한내과학회 1997 대한내과학회지 Vol.52 No.3

Objectives: Despite the fact that determinations of cadiorespiratory fitness levels by exercise stress tests are becoming widely used in healthy individuals as well as in patients with cardiopulmonary diseases, the normal standards in this field have not been well established in Korea. The purpose of this study is to provide normal standards or reference values for the VO2 max, HR max and O2 pulse max for normal Korean adults by age and sex, along with the derivation of regression formulae of these parameters. Methods: In 1,000 healthy adults (20-66years) consisting of 603men and 397women, symptomlimited maximal exercise was carried out by Bruce protocol, allowing holding on to the hand rail of the treadmill during exercise for the safety purpose. All the subjects were non-athletes and were members of a health center and were more conscious about their health and physical fitness than the ordinary population. Results: The VO2 max and HR max were decreased with age as expected and, as a whole, the values of the VO2 max and HR max of females were approximately 84% and 90% of those of males, respectively. Estimated yearly reductions in the V max for males and females were 0.45 and 0.32mL/kg/min, respectively and those of the HR max were 0.72 and 0.76/min, respectively. The O2 pulse max of the female was approximately 70% of that of the male, and was slightly related to weight and exercise time. The regression equations of the parameters obtained using exercise time (ET, sec), age (A, year), weight (W, kg) and sex (S, O=male; 1= female) were: HR max=215.3-0.74A-5,04S, O2 pulse max= 5.371+0.216W+0.0107ET-1.505S and VO2 max=40.612+1.950ET-0.206A-0.147W-6.060S, Conclusion: The VO2 max in our study was higher than hitherto reported. This was primarily due to longer exercise time of the subjects on the treadmill, because they were allowed to hold on to the hand rail during exercise. And also, the fact that our subjects, being members of a health center, might have had higher physical fitness levels than general population could have contributed to the high VO2 max. Thus, we feel that our results could be the ideal target or- reference values to be achieved for those patients or individuals who have to do the tests with holding on to the rail of a treadmill for safety purpose.

장천공과 Enteritis Cystica Profunda를 동반한 Peutz-Jeghers 증후군

안기성(Ki Sung Ahn),배정동(Jung Dong Bae),김호각(Ho Gak Kim),손호상(Ho Sang Shon),최정윤(Jung Yoon Choe),김지희(Chi Hui Kim),김이근(Ih Geun Kim),김태석(Tae Sug Kim),김채기(Chae Gi Kim) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.5

The Peutz-Jeghers syndrome is an autosornal dominant condition characterized by mucocutaneous pigmentation and hamartomatous polyps of the gastrointestinal tract. This syndrome is clinically important because of complications caused by gastrointestinal polyps, such as abdorninal pain, gastrointestinal bleeding and intussusception often leading to intestinal obstruction. The possibility of malignant change in the polyp has been a controversial issue. In the recent reviews of soe cases of Peutz-Jeghers syndrome, the reported lesions of small intestinal adenocarcinoma are regarded as the benign process of enteritis cystica profunda. We present herein a case of Peutz-Jeghers syndrome with small bowel perforation, a previously unreported instance, and enteritis cystica profunda. (Korean J Gastroenterol 1997; 29:677-682)

상부위장관질환 환자에서 H . pylori 감염에 의한 위점막의 조직학적 변화와 혈청 Gastrin 및 혈청 IgG항체가의 상관관계

손호상(Ho Sang Shon),최정윤(Jung Yoon Choe),김지희(Chi Hui Kim),김태석(Tae Sug Kim),김채기(Chae Gi Kim),김이근(Ih Geun Kim),안기성(Ki Sung Ahn),김호각(Ho Gak Kim),오훈규(Hoon Kyu Oh),김용진(Yong Jin Kim),배정동(Jung Dong Bae) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.3

N/A Background/Aims: This study was performed to investigate the relationship between Helicobacter pylori infection and degree of gastric mucosal inflammation, IgG antibody titer against H. pylori, and fasting serum gastrin level. Methods: Patients were divided into 2 groups(H. pylori positive and negative) by identification of H. pylori in biopsied specimens with special staining. In H. pylori positive group, the density of gastric K. pylori colonization was further graded semiquantitatively from 1 to 3. The severity of gastritis in each group was scored according to the Sydney system from 0 to 3. Serum IgG antibody titer against H. pylori was detected by second-generation antigen based enzyme immunoassay(Cobas Core Anti-Helicobacter pylori EIA). Fasting serum gastrin level was measured by standard radioimmunoassay technique. Results: The severity of gastritis in H. pylori positive group was significantly higher than H. pylori negative group in mononuclear cell infiltration(pC0.001), activity of PMNL(pC0.001), and glandular atrophy(pC0.01). In H. pylori positive group, the density of H. pylori colonization was significantly correlated with mononuclear cell infiltration(r=0.67, p0.001), activity of PMNL(r=0.70, p0.001), and grandular atrophy (r=0.38, pC0.001). Neither density of H. pylori colonization nor severity of gastritis was correlated with fasting gastrin level and IgG antibody titer against H. pylori. Conclusions: H. pylori infection results in localized inflammatory reaction in gastric mucosa with relation to density of H. pylori colonization, but serum H. pylori IgG antibody titer does not reflect the severity of gastritis. Fasting serum gastrin level also has no relation with the density of H. pylori colonization and severity of gastritis. These findings suggest that the factor which cause inflammation in gastric mucosa may be different from that cause gastrin secretion or formation of IgG antibody. (Korean J Gastroenterol 1996; 28:311 - 319)

자간증에 관한 임상적 고찰

김세광(SK Kim),황익하(IH Whang),이상용(SR Lee),홍순배(SB Hong),박찬규(CK Park),정순오(SO Chung) 대한산부인과학회 1978 Obstetrics & Gynecology Science Vol.21 No.9

1965년 1월부터 1976년 12월까지 만 12년간 연세대학교 의과대학 부속 세브란스병원 산부인과에 입원, 분만하였던 산모 총 21,704명중 224예의 자간증을 대상으로 의무기록부의 자료를 중심으로 임상통계학적으로 분석을 하여 다음과 같은 결과를 얻었다. 1) 총분만수에 대한 자간의 발생빈도는 1000분만당 10.3이었고, 연도별로는 특기할만한 변화가 없었다. 2) 임신자간, 분만자간, 산욕자간의 빈도는 각각 70.1%, 19.2%, 10.7%였다. 3) 연령별 분포는 분만수가 제일 많은 25-29세군에서 38.9%로 가장 많았다. 4) 경산회수별 분포는 초산부가 66.5%, 경산부가 33.5%였다. 5) 계절별로는 동계에 29.4%로 가장 많았고 춘계, 추계, 하계의 순이었다. 6) 임신기간에 따른 분포는 37-40주군이 66.5%로서 가장 많았고, 평균임신기간은 37.7주였다. 7) 산전관리를 받지 않았던 경우가 86.1%로 대부분을 차지하였다. 8) 경련회수는 1회가 29.5%로 가장 많았으며, 경련과 분만사이의 시간은 25-72시간군이 38.5%로서 가장 많았다. 9) 동반된 질환은 조기파막이 27.1%로서 가장 많았고, 빈혈이 22.9%, 쌍태아와 만성고혈압성 혈관질환이 각각 14.3%였다. 10) 분만방식은 질식분만이 88.9%, 제왕절개술이 11.1%였으며, 질식분만중 자연분만이 49.1%로서 가장 많았으며 제왕절개술의 적응증중 아두골반불균형이 6.2%로서 가장 많았다. 11) 질식분만의 마취는 회음부 차단마취가 52.2%로서 가장 많았으며, 국소마취와 전신마취가 각각 12.9%, 1.4%였으며, 제왕절개술시의 마취방법은 대부분이 전신마취였다. 12) 모성사망율은 자퇴하거나 전과시킨 경우를 제외하고는 자간증의 병발증으로 인하여 4명의 사망환자를 기록하여 모성사망율은 100,000 생아출생당 19였으며, 모성사망의 원인으로서는 패혈증, 뇌졸증, 폐부종 및 급성신부전증이었다. 13) 출생시 태아체중에 따른 예후는 사산이 11예, 신생아사망 8예로서 사산율은 1,000 출생당 48.2, 신생아사망율은 1,000 생아출생당 36.9로서 그 주산기사망율은 1,000 출생당 83.3이었다. 14) 태반의 무게는 600-699gm 군이 41.7%로서 가장 많았다. 15) 입원시에 혈압은 수축기혈압이 160-199mmHg군이 48.3%, 이완기혈압이 110-129mmHg군이 49.5%로서 가장 많았다. 16) 입원시 혈색소는 12.0-13.9gm%군이 49.1%로 가장 많았고, 10.0gm% 미만인 경우도 7.1% 있었으며, 혈구용적지표는 36.0-41.9%군이 48.7%로서 가장 많았다. 17) 혈액의 주요 화학적 검사소견인 Na, In order to study a variety of epidemiological and clinical aspects of ecalamptic patients, a retrospective survey of obstetric records of 224 eclamptic patients, who were admitted between 1965 and 1976, was carried out in the Yonsei University Medical Center. The results were as follows: 1. The incidence of eclampsia was 10.3 per 1,000 deliveries. 2. The distribution of antepartal, intrapartal, and postpartal eclampsia was 70.1%, 19.2%, and 10.7% respectively. 3. 38.9% of the patients were in the age 25-29, which was most prevalent childbirth group. 4. 66.5% of the patients were primigravids. 5. 29.4% of the patients occurred in winter which was followed by spring, autumn, and summer in order. 6. 66.5% were in the gestational period 37-40 weeks. The average duration of gestation was 37.7 weeks. 7. 86.1% of the patients received no antenatal care. 8. 29.5% of the patients had a single convulsion, which was most frequent number of convulsion. 38.5% of the patients convulsed within 25-72 hours before and after delivery. 9. Among the associated diseases, the incidence of SPRM was 27.1% and anemia, twins, chronic hypertensive vascular disease were 22.9%, 14.3%, 14.3% respectively. 10. 88.9% of the patients were delivered vaginally, 11.1% were performed cesarean section. Among the vaginal delivery, 49.1% delivered spontaneously. The most frequent indication for cesarean section was CPD(6.2%). 11. 52.2% of the patients received pudendal blocks. In case of cesarean section the majority had general anesthesia. 12. The maternal mortality from eclampsia managed in YUMC was 19 per 100,000 live births. 13. The stillbirth rate was 48.2 per 1,000 births and the neonatal mortality rate 36.9 per 1,000 live births. The overall perinatal mortality rate was 83.3 per 1,000 births. 14. 41.7% of the patients were in the placental weight 600-699, grams. 15. 48.3% of the patients were in the systolic BP 160-199mmHg on admission and 49.5% the diastolic BP 110-129mmHg. 16. 49.1% of the patients were in the hemoglobin level 12.0-13.9gm%

자동차 흡기계의 방사소음 예측에 대한 연구

김회전(Hoi-Jeon Kim),이정권(Jeong-Guon Ih),이성현(Seong-Hyun Lee),K. Shinoda,S. Kitahara 한국소음진동공학회 2005 한국소음진동공학회 학술대회논문집 Vol.2005 No.11

저가의 머신 비전 카메라를 이용한 2차원 진동의 측정 및 교정

김서우,이정권,Kim, Seo Woo,Ih, Jeong-Guon 한국음향학회 2018 韓國音響學會誌 Vol.37 No.2

현존하는 진동 측정 센서는 정밀도 면에서는 대부분의 진동을 측정하기에 충분하나, 센서 한 개로 하나의 지점이나 방향에 한정하여 측정할 수밖에 없다는 단점을 갖고 있다. 반면 카메라의 경우, 정밀도나 측정 가능한 주파수 영역의 면에서는 다소 불리하지만, 한 번에 광범위한 영역의 진동을 측정할 수 있고 가격 면에서 유리하며 다자유도의 진동을 동시에 측정할 수 있다는 큰 장점을 갖고 있다. 본 연구에서는 저가의 머신 비전 카메라가 진동 측정 센서로서 어느 정도의 오차 범위 내에서 진동을 측정할 수 있는지 알아본 후, 실제 외팔보의 진동을 측정하였다. 카메라의 2차원 평면 이미지는 두 방향의 직선 운동과 한 방향의 회전 운동을 나타낼 수 있다. 먼저 단일 점의 진동을 카메라로 측정하고, LDV(Laser Doppler Vibrometer) 측정을 기준으로 한 카메라 측정의 오차를 실험적으로 교정하였다. 다음으로 다중점의 진동을 한 번에 측정하여 회전 진동과 외팔보 전체 형상의 진동을 측정하였다. 외팔보 전체 형상 진동은 주파수와 시간 영역 모두에 대하여 분석하였다. The precision of the vibration-sensors, contact or non-contact types, is usually satisfactory for the practical measurement applications, but a sensor is confined to the measurement of a point or a direction. Although the precision and frequency span of the low-cost camera are inferior to these sensors, it has the merits in the cost and in the capability of simultaneous measurement of a large vibrating area. Furthermore, a camera can measure multi-degrees-of-freedom of a vibrating object simultaneously. In this study, the calibration method and the dynamic characteristics of the low-cost machine vision camera as a sensor are studied with a demonstrating example of the two-dimensional vibration of a cantilever beam. The planar image of the camera shot reveals two rectilinear and one rotational motion. The rectilinear vibration motion of a single point is first measured using a camera and the camera is experimentally calibrated by calculating error referencing the LDV (Laser Doppler Vibrometer) measurement. Then, by measuring the motion of multiple points at once, the rotational vibration motion and the whole vibration motion of the cantilever beam are measured. The whole vibration motion of the cantilever beam is analyzed both in time and frequency domain.

이론적 해 및 경계요소법에 의한 2차원 흡음형 소음기의 전달 손실치 예측 비교

김회전(Hoi-Jeon Kim),이정권(Jeong-Guon Ih),정지훈(Ji-Hoon Jeong) 한국소음진동공학회 2002 한국소음진동공학회 학술대회논문집 Vol.2002 No.5