울산으로부터의 통신 : 패장 이상범 위원장의 자신감

김욱진 사회평론 1991 월간 사회평론 Vol.91 No.4

ITS 염기서열 기반 방기 신속 감별용 SCAR marker 개발

김욱진,노수민,최고야,문병철 대한본초학회 2022 大韓本草學會誌 Vol.37 No.4

Objectives : In the Korean Pharmacopoeia 12th edition (KP 12) and the Korean Herbal Pharmacopoeia (KHP), two authentic herbal medicines are described, namely Bang-gi (Cheong-pung-deung) and Mok-bang-gi, respectively. In China, Bun-bang-gi is also used as herbal medicine. This study was conducted to develop a molecular authentication tool for distinguishing the three herbal medicine used as Bang-gi, which are Sinomeni Caulis et Rhizoma (Rhizome of Sinomenium acutum), Stephaniae Tetrandrae Radix (Root of Stephania terandra), and Cocculi Radix (Root of Cocculus trilobus). Methods : Twelve samples of three species (four samples of S. acutum, five samples of S. tetrandra, and three samples of C. trilobus) were collected from different habitats. The sequences of internal transcribed spacer (ITS) regions were obtained and comparatively analyzed to design the species-specific sequence characterized amplified region (SCAR) primers. The specificity of each pair of SCAR primers that amplified species-specific amplicon was evaluated for establishing the singleplex and multiplex PCR assay tools. Results : The singleplex SCAR markers show discriminability in C. acutum, S. tetrandra, and C. trilobus. These SCAR markers were also efficiently authenticated three species in the multiplex SCAR amplification using single PCR reaction. Furthermore, these PCR assay methods were applicable to authenticate dried herbal medicines distributed in the markets. Conclusions : The SCAR markers and PCR assay tools help discriminate the three herbal medicines used as Bang-gi at the species levels and provide a reliable genetic method to prevent the inauthentic distribution of these herbal medicines.

Analysis of Genetic Similarity Detected by AFLPand PCoA among Genotypes of Kenaf (Hibiscus cannabinus L.)

김욱진,김동섭,김상훈,김진백,고은종,강시용 한국작물학회 2010 Journal of crop science and biotechnology Vol.13 No.4

Seventeen kenaf varieties collected from several regions around Asia and Europe were grown in Korea and their genetic diversity was analyzed using morphological characters and AFLP technique. In the morphological analysis, the 17 varieties were divided into two major groups according to stem diameter, plant height, and flowering periods. The late varieties, which could yield more biomass compared with the early-medium varieties, were included in one of two major groups . Nonetheless, it is difficult to identify individual varieties based on morphological characters because of their limited variation. For the AFLP analysis, 34 primer combinations generated a total of 3,193 polymorphic bands (out of 3,914) with a polymorphic rate of 82%. The clusters were divided into two major groups with a similarity coefficient of 0.63 by UPGMA analysis method; but each group did not show a common tendency. Additionally, the results of the AFLP analysis did not show similar tendency compared with morphological data, a result that might be explained in terms of convergent evolution, i.e. the acquisition of morphologically similar traits between distinctly unrelated varieties.

폐에 발생한 경화성 혈관종

김욱진 대한흉부심장혈관외과학회 1990 Journal of Chest Surgery (J Chest Surg) Vol.23 No.5

Sclerosing hemangiomas of lung are benign neoplasms of uncertain histogenesis. They have variegated histologic appearance characterized by an admixture of solid, hemorrhagic, papillary and sclerotic lesions. We have experienced a case of sclerosing hemangioma of lung recently. She was 43 year-old woman and suffered only from mild vague chest pain. Well circumscribed round mass was placed at the right hilum. Mass enucleation was done and she was recovered and discharged with event free.

흉부둔상에 의한 외상성 가성 폐기낭

김욱진 대한흉부심장혈관외과학회 1990 Journal of Chest Surgery (J Chest Surg) Vol.23 No.5

Pseudocysts of lung by blunt chest trauma are rare lesion with 1 to 2 % incidence. The symptoms are nonspecific and misled or confused with lung abscess or congenital cystic disease of lung occasionally. Diagnosis is not difficult by radiographic findings and history of blunt chest trauma. There courses are benign and spontaneously absorbed and require no specific treatment mostly. Recently, we had the one case of 8 year-old female with traumatic lung cyst and its cavities filled the entire right lower lobe. The destruction of lung was severe, so, right lower lobectomy was done and recovered, discharged without event.

주거환경만족도가 매입임대주택 입주민의 건강에 미치는 영향 -동네응집력의 매개효과와 거주기간의 조절효과

김욱진,김태연 한국사회복지행정학회 2020 한국사회복지행정학 Vol.22 No.4

본 연구의 목적은 매입임대주택 입주민의 주거환경만족도와 건강의 관계에서 동네응집력의 매개효과와 거주기간의 조절효과를 검증하는 것이다. 분석자료는「2018년 서울시 매입임대주택 공급 및 관리 실태조사」에서 추출하였고, 연구참여자는 서울시 소재 매입임대주택 270동 입주민 540명으로 정하였다. 분석방법으로는 구조방정식모형을 이용하였다. 분석 결과, 주거환경만족도는 건강과 동네응집력에 직접적으로 정적인 영향을 미쳤고, 동네응집력은 건강에 직접적으로 정적인 영향을 미쳤으며, 주거환경만족도는 동네응집력을 매개로 건강에 간접적으로 정적인 영향을 미치는 것으로 나타나 동네응집력의 매개효과를 확인하였다. 또한, 동네응집력이 건강에 미치는 직접적인 정적 영향은 현 주택에 거주한 시간이 짧은 경우에 비하여 긴 경우 유의미하게 커 거주기간의 조절효과도 일부 확인하였다. 연구결과를 토대로 매입임대주택사업의 개선방안을 주거환경 개선, 주택관리 및 운영체계 효율화, 공동체 활성화 사업 추진 등의 측면에서 제시하였다.

[토론문] 사회복지서비스 재정의 지방화와 지역의 대응

김욱진 한국사회복지행정학회 2013 한국사회복지행정학회 학술대회 자료집 Vol.2013 No.10

Phenotyping analysis of p53 knockout mice produced by gene editing and comparison with conventional p53 knockout mice

김욱진,C‑Yoon Kim,오한슬,이지민,장서나,유보경,김진,이한웅,박재학 한국유전학회 2019 Genes & Genomics Vol.41 No.6

Background Knockout (KO) mice developed by homologous recombination (HR) have become useful tools to elucidate gene function. However, HR has low KO efficiency and is time-consuming, labor-intensive, and expensive. ‘Gene editing’ has received much attention for efficient genetic manipulation. Objective As generation of KO mice is simplified, KO mice produced by HR can be feasibly reproduced using gene editing. However, phenotyping analysis and comparison between KO mice produced by these two techniques is necessary. Methods We generated p53 KO mice through gene editing and compared their phenotype with the already reported HRmediated p53 KO mice. Results Tumors occurred in 36 (73%) of 49 homozygous KO mice and the mean age of occurrence was 23 weeks, with lymphoma (64%) and sarcoma (23%) being the most common. Tumors were also developed in 12 heterozygous mice and the mean age of occurrence was 40 weeks, with sarcoma (54%) and lymphoma (46%) in high proportion. Homozygotes had a mean life span of 157 ± 52 days and developmental abnormalities were found in females compared to in males (P < 0.05, P < 0.001). Conclusion We analyzed the basic phenotype of p53 KO mice and observed no significant difference from the conventional HR-mediated p53 KO mice.

2002년 농약중독 사망자 통계청 자료 분석 및 제초제 중독으로 인한 사망사고 예방 대책

김욱진,김효윤,김승환,김선욱,조영순,정성필,이한식,Kim Uk Jin,Kim Hyo Yun,Kim Seung Hwan,Kim Sun Wook,Cho Young Soon,Chung Sung Pil,Lee Hahn Shick 대한임상독성학회 2004 대한임상독성학회지 Vol.2 No.2

Backgrounds: Deaths from pesticides poisoning has increased annually, but no studies have been reported. Especially paraquat is suspected to be a major material in pesticide poisoning deaths. In Korea, simple epidemiology of pesticides poisoning is not well known. So, there is no effective method to prevent pesticides poisoning. We tried to investigate the present status of pesticides poisoning with data from Korea National Statistical Office and suggest an effective counterplan. Methods: We analysed death cause data derived from Korean Statistical association, deaths causes being pesticides poisoning in the year 2002. Also, we investigated data from internet, mainly from Korea National Statistical Office home page. Results: Total 2,875 persons died after pesticides poisoning in 2002 year. Average age is 54.2 year, standard deviation being 17.7 year. Many victims (about $41\%$) died during the herbicides' non-necessary period (JanuaryMarch, October-December) Conclusion: Herbicides sale should be restricted only during herbicides' necessary period, and so called a pesticides safety supervisor system shall effectively prevent herbicides poisoning.

Korean Immigrant Businesses Departing Inner-City African-American Neighborhoods: The Case of Chicago

김욱진 전남대학교 글로벌디아스포라연구소 2012 디아스포라 연구 Vol.6 No.2

This study identifies a determining factor that affects the departure of Korean immigrant businesses from inner-city African-American neighborhoods. Data for this study come from a sample survey of 132 Korean immigrant business owners in the Chicago area. A major finding is that owners’ favorable perception of external economic opportunities, rather than conflicts with African-American customers or residents represents the major factor that contributes to Korean immigrant businesses leaving inner-city African-American neighborhoods. This finding suggests an alternative that invalidates the conflict-centered perspective commonly found in the literature on Korean-American entrepreneurship, instead putting economic factors at the forefront of the analysis.