산전 진단된 수신증의 임상 경과 - 단일 기관의 경험 -

김연희,김병주,박문성,양정인,김행수,김병길,배기수,Kim Yeun-Hee,Kim Byoung-Ju,Park Moon-Sung,Yang Jung-In,Kim Haeng-Soo,Kim Pyung-Kil,Pai Ki-Soo 대한소아신장학회 2002 Childhood kidney diseases Vol.6 No.2

목적: 산전 초음파가 널리 이용되면서 태아기의 선천성 요로계의 이상이 발견되는 경우가 점차 증가하고 있다. 수신증의 대부분은 출생 후 1년 내에 자연스럽게 없어지는 생리적 수신증이지만 수술적 교정을 요하는 병적 수신증과의 감별이 쉽지 않다. 본 연구에서는 산전 수신증이 의심되는 환아에서 출생 후 수신증을 확진하여 산전 진단과의 연관성을 비교 분석하고, 산전 수신증의 원인과 자연경과를 이해하여 출생 후 수신증에 대한 대처에 도움을 주고자 본 연구를 시행하였다. 방법: 1994년 9월부터 2001년 8월까지 아주대학교 병원 산과에 등록되어 산전 초음파 검사상 태아 수신증이 의심되었던 환아 119명 중 출생후 실시한 신 초음파 검사에서 수신증이 확진된 91명(121 신단위)을 대상으로 수신증의 원인과 자연경과를 신 초음파 검사와 배설성 신주사 검사로 추적 관찰하였다. 결과: 산전 초음파 검사에서 수신증이 의심되었던 119명의 신생아 중 출생 후 수신증이 확진 되었던 환아는 91명으로 76%였다. 수신증의 원인으로 요관 신우 이행부 협착이 57례(47%)로 가장 많았으며 그 다음으로는 다낭성 이형성신이 12례(10%), 요관 방광 이행부 협착 5례(4%), 방광 요관 역류 5례(4%), 후부요도 판막 2례(2%)등의 눈이었으며 원인을 찾을 수 없었던 경우도 38례(31%)였다. 추적검사에서 47%가 수신증의 완전소식 혹은 호전소견을 보였으며 총 121개의 신 단위 중 10단위가 수술을 받았으며 진단에서 수술까지는 평균 7.2개원이 걸렸다. 결론: 산전 초음파로 발견된 수신증의 대부분은 출생후 수신증으로 확진되었으나 정상인 경우도 있었다. 산전 수신증의 원인으로 요관 신우 이행부 폐쇄가 가장 많았으며 대부분은 비폐색성 수신증이었고, 추적 검사에서 호전되는 경우가 많았다. 그러나 아직까지 신생아 수신증은 정확한 감별진단이 어렵기 때문에 신장기능의 보전을 위해서는 수신증의 정도에 따라 적절한 간격으로 지속적인 관찰을 하는 것이 필요할 것으로 사료된다. Purpose : The detection of hydronephrosis(HN) with antenatal ultrasonography was first reported in the 1970s. Prenatal HN is diagnosed with an incidence of 1:100 to 1:500 on antenatal screening. Recently, the purpose of antenatal screening has changed from simple detection to selection for specific diagnosis-based management. this study is to evaluate the usefulness of antenatal sonography for HN and to investigate the differential causes of HN and their clinical outcomes. Patients and methods : 11,783 live neonates with prenatal ultrasonographic examination at Ajou University School of Medicine, from Sep. 1994 to Aug. 2001 were analyzed. Results and conclusion : Hydronephrosis (>10 mm) was detected in 119 (1.0%) cases antenatally and among these, 91 were proved to have HN postnatally Males were three times more affected than females. Additional imaging studies revealed that ureteropelvic junction obstruction was the most common postnatal diagnosis (47%), followed by multicystic dysplastic kidney, vesicoureteral junction obstruction and vesicoureteral reflux. During 20 months' follow-up(3 to 72 months), 58(48%) renal units showed spontaneous resolution and surgical interventions were necessary in 10 (7.4%) of postnatally confirmed hydronephrotic renal units.

Oxidative Synthesis of Benzoylpteridines from Benzylpteridines by Potassium Permanganate

김연희,강용한,백대진,Kim, Yeon Hui,Gang, Yong Han,Baek, Dae Jin Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.2

6- and 7-Benzylpteridine derivatives have been converted to the corresponding 6- and 7-benzoylpteridines by the oxidation reaction with KMnO4. The newly synthesized compounds have been characterized by pKa determinations, UV, and 1H-NMR spectra.

급성 림프구성 백혈병 환아에서 발생한 거대세포바이러스망막염 1예

김연희,김상국,Youn Hui Kim,Sang Kook Kim 대한안과학회 2006 대한안과학회지 Vol.47 No.6

Purpose: To report a case of cytomegalovirus (CMV) retinitis in a child who had been managed by immunosuppressive chemotherapy for acute lymphoblastic leukemia (ALL). Methods: An 8-year-old boy who had been managed by immunosuppressive chemotherapy for ALL was referred to the ophthalmologic clinic because of blurred vision in his right eye. Fundus examination showed hard exudates and white retinal leaion in the macular area of the right eye, white retinal lesion accompanied with retinal hemorrhage and exudates in the midperipheral retina of the left eye. Serologic tests demonstrated a positive response of CMV antibody IgG and a negative response of CMV antibody IgM. CMV was isolated upon the culture of bone marrow and peripheral blood. Immunosuppressive chemotherapy was discontinued and ganciclovir was administered. Results: Administration of ganciclovir led to clinical stabilization of the retinitis lesion that was accompanied by scarring. We were able to discontinue the administration of ganciclovir after the retinal lesions were resolved, and no recurrence of CMV retinitis was noted. Conclusions: Ganciclovir treatment was clinically effective in improving CMV retinitis in an immunocompromised child with ALL. In addition, the improved systemic immune function achieved by discontinuing immunosuppressive chemotherapy permitted discontinuation of anticytomegalovirus therapy.

청계천 복원 전.후 기상관측을 통한 도시기후 변화

김연희,Kim, Yeon-Hui 한국하천협회 2006 하천과 문화 Vol.2 No.3

난류형 클린룸내의 Layout 변화에 따른 분진제거 특성에 관한 연구

김연희,Kim, Yeon-Hui 한국건설안전협회 2007 建設 安全技術 Vol.41 No.-

The purpose of this paper is to investigate the removal efficiency of fine dusts as the configuration condition of machinery and equipments in Clean Room and to analyze the flowing behaviors of fine dusts as the layout of Clean Room. The layout of the Clean Room was classified into side layout type, 2 center line type and center concentration type layout, and the flow rates used in this research were 0.22m/s, 0.44m/s and0.80m/s. Dust removal efficiency as layout change was decreased 37% for side layout type, 31% for 2 centerline type and 20% for center concentration type layout at the flow rate of 0.22m/s, compared with the state without machinery and equipments in Clean Room. The efficiency was decreased 42% for side layout type,22% for 2 center line type and 8% for center concentration type layout at the flow rate of 0.44m/s, and decreased 20% for side layout type, 18% for 2 center line type and 10% for center concentration type layout at the flow rate of 0.80m/s. According to the result of dust removal behavior, $0.3\mum$, $1\mum$and $3\mum$dust except for $5\mum$showed the higher change of the behavior in side layout type than in center concentration type layout due to the change of air flow. It was confirmed that removal behavior depends on the layout of machinery and equipments as the dust size decreases.

콘텐츠라인-게임넷2005

김연희,Kim, Yeon-Hui 한국데이터베이스진흥원 2005 디지털콘텐츠 Vol.5 No.-

올해로 52회째를 맞는 NCTA(National Cable & Telecommunications Association)의‘내셔널 쇼’가 미국 샌프란시스코 모스코니 센터(Moscone Center)에서 세계 각지에서 몰려든 참관자들로 북적거리는 가운데 지난 지난달 5일까지 3일 동안 개최됐다.

COVID-19 관련 업무 경험이 간호사의 직무 스트레스에 주는 영향

김연희,주현실,이정언,이미선,Kim, Yeon Hee,Joo, Hyun Sil,Lee, Jeong Eon,Lee, Mi Sun 한국직업건강간호학회 2022 한국직업건강간호학회지 Vol.31 No.4

Purpose: This study aimed to compare and analyze the job stress of nurses with and without in COVID-19-related work. Methods: A structured self-reported questionnaire survey was conducted to assess job stress. The extent of job stress was compared between nurses with COVID-19 (COVID-19 group) and those without such experience (non-COVID-19 group). Multiple regression analysis was performed to identify the factors influencing job stress. Results: Job stress was higher in the COVID-19 group compared to the non-COVID-19 group (t=2.54, p=.12). In sub-categorical comparison, stress driven by a taxing work environment, relationship conflict, and work schedule was higher in the COVID-19 group than the non-COVID-19 group. Multiple regression analysis revealed the job stress was higher among nurses with COVID-19-related work experience than that of non-experienced nurses. The factors affecting job stress of nurses with COVID-19-related work experience included emergency room work, providing nursing assistant for COVID-patients, and caring for these patients. Conclusion: Since COVID-19-related work experience is a major factor that affects nurses' job stress, it is imperative to provide various support measures for nursing assistants such as providing a break from working in an environment with high risk of infection, adjusting work schedules, resolving conflicts between personnel, and securing support.

Synthesis and Characterization of Novel Polyimides Containing Bulky Trimethylsilylphenyl Group

김연희,Kim, Yeon Hui Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.5

속발내사시에서 프레넬프리즘의 치료 효과

김연희,최미영,Youn Hui Kim,Mi Young Choi 대한안과학회 2006 대한안과학회지 Vol.47 No.10

망막중심정맥폐쇄에서 시신경유두부종의 유무에 따른 형광안저혈관조영소견

김연희,김상국.Youn Hui Kim. M.D.. Sang Kook Kim. M.D.. Ph.D. 대한안과학회 2007 대한안과학회지 Vol.48 No.11

Purpose: To investigate the characteristics of fluorescein angiograms (FAG) of the optic nerve head and retina according to the presence of optic nerve head swelling (ONHS) in central retinal vein occlusion (CRVO). Methods: The records of 69 eyes were reviewed, confirmed with the diagnosis of CRVO, and compared for several features according to the presence of ONHS. The best-corrected visual acuities and intraocular pressures were recorded and patterns of retinal hemorrhage were described. The presence of fluorescein filling defects of the optic disc, time till fluorescein started to fill at the optic disc, arteriovenous transit time, and nonperfused areas were assessed using FAG. Results: Forty-one patients without ONHS (group 1) and 28 patients with ONHS (group 2) were included. The mean ages for groups 1 and 2 were 61.4 and 56.9 years, respectively, and there was no significant difference the mean ages between the groups. The fluorescein filling defect of the optic disc was seen more often in group 1 (n=13) than in group 2 (n=2). Marginal irregularity of the foveal avascular zone due to perifoveal capillary drop out was seen significantly more often in group 1 (n=12) than in group 2 (n=2). Conclusions: Fluorescein filling defects of the optic disc and perifoveal capillary drop out were more frequently seen in CRVO patients without ONHS. However, longitudinal studies are needed to confirm the prognostic value of ONHS and the correlation of filling defects with progressive optic neuropathy in CRVO.