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양종규,김성욱,백승철,김정원,김석영 ( Jong Kyu Yang,Sung Wook Kim,Seung Churl Paik,Chung Won Kim,Suk Young Kim ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.3
Iatrogenically developed immunosuppression-associated Kaposis sarcoma is the result of immunosuppressive therapy after an organ transplantation, particularly after a renal transplantation. Since the advent of powerful immunosuppressive agents such as cyclosporine, recently the incidence of Kaposis sarcoma has been increased. In addition to immunosuppression, other factors, such as genetic predisposition, environmental and geographic factors, and oncogenic viruses, may play a role in the pathogenesis of this tumor. Ilerein we report a case of Keposis sarcoma with multiple organ involvement of the skin, lung, small intestine and mesenteric lymph node in a renal allograft recipient who received cyclosporine and prednisolone. Reduction of the dosage of immunosuppressant for 1 month resulted in improvement of the cutaneous lesions. (Kor J Dermatol 1997;35(3): 551-555)