특발성 황반전막에서 빛간섭단층촬영상의 형태학적 분류에 따른 수술 전후 망막층별 두께변화분석

김상원,박재홍,안동섭,윤희성,Sang Won Kim,Jae Hong Park,Dong Seob Ahn,Hee Seong Yoon 대한안과학회 2014 대한안과학회지 Vol.55 No.12

Purpose: To evaluate the changes in each retinal layer thickness according to preoperative optical coherence tomography (OCT) patterns after idiopathic epiretinal membrane (ERM) removal and to investigate the correlation between retinal layer thickness and visual improvement. Methods: The medical records of 63 patients (63 eyes) who underwent vitrectomy with internal limiting membrane (ILM) peeling for idiopathic ERM and followed for more than 6 months were retrospectively reviewed. The OCT images of preoperative idiopathic ERM were classified into 3 patterns being flat, convex, and concave. Then, the changes of each retinal layer thickness were compared among OCT patterns and the correlations between retinal layer thickness and visual improvement were analyzed. Results: Improvement in visual acuity was measured in the following order: concave, flat, and convex patterns. The patients with the convex pattern only showed significant improvement of visual acuity. Ganglion cell layer plus inner plexiform layer (GCL + IPL), inner nuclear layer (INL), and outer plexiform layer (OPL) thicknesses were significantly larger in preoperative ERM patients than in normal controls in the following order: convex, concave, and flat patterns. Retinal layer thickness decreased significantly in GCL + IPL and INL after surgery in convex, flat, and concave patterns, in that order. Generally, preoperative retinal layer thickness and postoperative visual acuity were not correlated. However, improvement of visual acuity was significantly related to GCL + IPL and INL thicknesses in the convex pattern and IPL thickness in the flat pattern. Conclusions: In patients with idiopathic ERM, preoperative difference in each retinal layer thickness according to preoperative OCT patterns was observed. After ERM removal, reduction of each retinal layer thickness and specific retinal layer related to visual improvement was different according to preoperative OCT patterns.J Korean Ophthalmol Soc 2014;55(12):1843-1852

가쪽눈꺼풀판띠고정술과 퀴커트 봉합술을 동시에 시행한 퇴행성 눈꺼풀속말림의 치료결과분석

김상원,이우석,노주헌,Sang Won Kim,MD,Woo Seok Lee,MD,Joo Heon Rho,MD 대한안과학회 2012 대한안과학회지 Vol.53 No.9

Purpose: To evaluate long-term effectiveness of lateral tarsal strip procedure combined with Quickert sutures in correcting involutional entropion. Methods: The retrospective study reviewed 82 eyes of 71 patients with involutional entropion whose follow-up period was more than 6 months among patients who underwent lateral tarsal strip procedure combined with Quickert sutures between February 2003 and February 2010. Results: The postoperative follow-up period was 6 months to 78 months (average 40.2 months) and the average age was 63.5 years. Out of 82 eyes, 3 eyes recurred and the recurrence rate in the lateral tarsal strip procedure combined with Quickert sutures was 3.6%; postoperative overcorrection was not observed. Out of the 3 recurrence cases, 2 eyes both recurred 6 months after the operation and were treated by Quickert sutures alone with no recurrence. The other case recurred 1 year and 4 months after lateral tarsal strip procedure combined with Quickert sutures and was corrected by this operation again. There was no recurrence for a follow-up period of 2 years. Conclusions: An effective approach was obtained during long-term follow-up when lateral tarsal strip procedure combined with Quickert sutures was conducted as repairing operations in involutional entropion. The approach showed lower recurrence rate than the existing reports of operations such as lateral tarsal strip procedure or Quickert sutures when conducted alone and provided long-lasting effectiveness in the correction of involutional entropion. J Korean Ophthalmol Soc 2012;53(9):1213-1218

난시교정인공수정체 삽입 후 난시교정 평가를 위한 KR-1W 수차계의 유용성

김상원,한상엽,이경헌,Sang Won Kim,Sang Youp Han,Kyung Hun Lee 대한안과학회 2012 대한안과학회지 Vol.53 No.11

Purpose: To evaluate the efficacy of the KR-1W aberrometer in assessing the astigmatism and the achieved axis after AcrySof Toric intraocular lens (IOL) implantation. Methods: Thirty-nine patients (48 eyes) that had undergone phacoemulsification and AcrySof Toric IOL implantation were included in the present study. At postoperative 1 month, ocular aberrations of all the eyes were measured using the KR-1W aberrometer before mydriasis and the achieved axis of AcrySof Toric IOL was measured by slit lamp examination after mydriasis. The achieved axis measured by slit lamp examination and the astigmatism of the implanted AcrySof Toric IOL were compared with the KR-1W. Results: The mean achieved lens axis after mydriasis measured by slit lamp examination and KR-1W was 86.43 ± 47.49 degrees and 88.93 ± 41.22 degrees, respectively. The correlation coefficient of the 2 methods was 0.992 (p < 0.001). The measured astigmatism according to the AcrySof Toric IOL model was 1.11 ± 0.47D in SN60T3, 1.71 ± 0.51D in SN60T4, and 3.32 ± 0.78D in SN60T5. Conclusions: Without the need to directly evaluate the axis of implanted Toric IOL after mydriasis, the achieved lens axis can be measured by the KR-1W without mydriasis. The AcrySof Toric IOL model could be assessed by the KR-1W without information about the AcrySof Toric IOL model.

Vinylogous Intramolecular Nucleophilic Acyl Substitution Reactions Mediated by Samarium(II) Iodide

김상원,이효원,강한영,Kim, Sang Won,Lee, Hyo Won,Gang, Han Yeong Korean Chemical Society 2000 Bulletin of the Korean Chemical Society Vol.21 No.12

건전한 생활 습관은 성인병을 예방한다

김상원,Kim, Sang-Won 한국건강관리협회 1990 건강소식 Vol.14 No.9

방사선치료를 받는 말기암환자들을 대상으로 한 이완요법

김상원,전미선,김효신,Kim, Sang-Won,Chun, Mison,Kim, Hyo Shin 한국호스피스완화의료학회 2016 한국호스피스.완화의료학회지 Vol.19 No.3

방사선치료는 암과 관련된 증상을 완화시키는 목적으로 자주 사용되고 있다. 정확하고 안전한 방사선치료를 받기 위해서는 방사선이 나오는 동안 치료 테이블 위에 가만히 누워 있어야 한다. 그러나 일부 환자는 기질적인 문제 외에 심리적인 문제에서 기인한 증상으로 인해 가만히 누워 있지 못한다. 이 논문에서는 모의치료 단계 전부터 치료 테이블에 바로 누워 있지 못했지만 별 다른 장소에서의 교육 참여 없이 침상에서 쉽게 할 수 있는 이완요법을 배워 방사선치료 하는 동안 가만히 누워 있는 게 가능했던 두 명의 말기암환자 사례를 보고하고자 한다. Radiation therapy is an effective modality to alleviate cancer-related symptoms. To deliver radiation accurately, it is essential to secure stability of the treatment position in patients during each treatment time. However, some patients could be less cooperative due to their psychoemotional issues. We present two cases of terminal-stage cancer patients who were initially unable to lie still on the treatment table before simulation. A relaxation technique was taught to them on the bed, and they could relax and undergo radiation therapy with effective symptom relief.

$({Fe_{0.6}}{Co_{0.4}})_{89}$${Zr_{11}$/$({Fe_{1-x}}{Co_x})$$Zr_{11}$(x=0, 0.6, 0.9)비정질 다층박막의 자기특성

김상원,Kim, Sang-Won 한국재료학회 2000 한국재료학회지 Vol.10 No.10

SAW 소자에 응용 가능한 자성박막재의 개발을 목적으로 RF 스퍼터링법으로 증착한 (Fe(sub)0.6Co(sub)0.4)(sub)89Zr(sub)11/Fe(sub)1-xCo(sub)x)Zr(sub)11(x=0, 0.6, 0.9)<원문잠조> 비정질 다층박막의 자기특성을 조사하였다. 수직자기장중열처리를 행하였을 때 상온에서 비자성 Fe(sub)89Zr(sub)11 층의 삽입에서만 다층박막화의 효과가 나타났다. 일 예로 (Fe(sub)0.6Co(sub)0.4)(sub)89Zr(sub)11(30${\AA}$)/Fe(sub)89-Zr(sub)11(40${\AA}$)<원문참조> 박막시편에 1kHz, 50 mOe의 여기자기장으로 평가된 최대 미분투자율${\mu}$(sub)d.max는 단층막의 750에서 1650으로 2배 이상 증가, 구동 바이어스자기장 Hw는 20 Oe에서 6Oe로 3배 이하로 감소하는 양호한 특성이 얻어졌다. 그러나 다른 중용 특성인 자왜는 34% 정도 감소하는 것으로 추정되었다.

핀테크 활성화 방안 연구: 미국, 중국, 한국의 규제 현황 중심으로

김상원,임석진,Kim, Sang-Won,Im, Seokjin 대한산업경영학회 2021 산업융합연구 Vol.19 No.4

IT를 융합한 새로운 형태의 금융 산업인 핀테크는 미국, 중국과 같은 선진국을 중심으로 비약적으로 발전하고 있다. 미국과 중국은 핀테크 산업의 발전과 규모의 확대를 위해 규제 완화를 통해 진입장벽을 낮췄으며, 하나의 예로 스타트업 기업들에게는 기존의 규제에 비해 더욱 완화된 또는 일정 기간 동안 규제를 적용하지 않는 방식의 negative 규제를 통해 다양한 아이디어들이 접목될 수 있도록 유도하였다. 미국과 중국은 기존에 있던 금융권의 규제들을 핀테크 산업에 적용하지 않아 핀테크 스타트업들이 보다 쉽게 성장할 수 있는 환경을 제공하였다. 현재 한국에서는 '삼성페이'와 '토스', '카카오페이' 등과 같이 핀테크 기술을 개발하여 활성화되고 있고, 그 규모도 확대되고 있다. 핀테크 발전을 위해 여러 가지 제도를 정비하고 규제를 도입하고 있지만 금융권과 각종 시장의 비우호적이고 비개방적인 규제 때문에 핀테크의 성장 속도가 느리다. 본 논문은 핀테크 선진국과 한국을 중심으로 핀테크 현황을 파악하고 핀테크 산업 발전을 저해하는 핀테크 관련 규제를 살펴본 후에, 핀테크 발전을 위한 해결방안으로서 positive 규제에서 negative 규제로, 사전 규제에서 사후 규제하는 등 금융 분야의 과도한 규제를 보다 유연하게 완화하는 방안을 제안한다. Fintech, a new form of financial industry that converges IT, is developing rapidly in developed countries such as the US and China. The U.S. and China lowered barriers to entry through deregulation to develop and expand the fintech industry, and, for example, encouraged startup companies to incorporate various ideas through negative regulations that are more relaxed or do not apply regulations for a certain period of time. The U.S. and China did not apply existing financial regulations to the fintech industry, providing an environment where fintech startups could grow more easily. Currently, in Korea, fintech technologies such as 'Samsung Pay', 'Toss' and 'Kakao Pay' have been developed and are being activated, and also their scale is expanding. Although various systems are being reorganized and regulated for the development of Fintech, Fintech's growth rate is slow due to unfriendly and unopened regulations in the financial sector and various markets. This paper examines the status of fintech, focusing on advanced fintech and Korea, and examines fintech-related regulations that hinder the development of the fintech industry. We propose a more flexible way of easing excessive regulation in the financial sector, such as post-regulation.

한국 연근해산 두족류 (Octopus minor, Octopus ocellatus and Todarodes pacificus) 성숙정자의 미세구조 II

김상원,장남섭,Kim, Sang-Won,Chang, Nam-Sub 한국현미경학회 2001 Applied microscopy Vol.31 No.4

두족류 3종(Octopus minor, Octopus ocellatus, Todarodes pacificus)의 성숙정자를 전자현미경을 통해 관찰한 결과 다음과 같았다. 팔완류인 서해박지와 주꾸미의 성숙정자 전체 길이는 각각 $390{\mu}m$와 $125\sim130{\mu}m$정도였고, 십완류인 살오징어의 길이는 $35{\mu}m$정도로 매우 짧았다. 서해낙지는 나선형의 첨체와 약간 굽은 바나나 모양의 머리를 소지하고 있었으며, 주꾸미는 꼬인 첨체와 막대 모양의 긴 머리를 가지고 있었다. 이들 침체 내강에는 규칙적 구조(periodic structure)인 많은 가로무늬가 관찰되었고, 머리의 내강에는 치밀전 (dense plug)을 형성하였다. 그러나 살오징어의 첨체는 전자밀도가 낮은 둥근 모자 모양이 였으며, 머리는 길쪽한 장타원형을 나타내었다. 특히 첨체 하단부에는 2개의 작은 강(cavity)이 관찰되었고, 이들 내강에는 전자밀도가 높은 물질들(juxtanuclear acrosomal materials)로 채워져 있었다. 3종의 성숙정자 중편은 서해낙지와 주꾸미에서 미토콘드리아가 mitochondrial sleeve를 형성하였지만, 두 종간 미토콘드리아의 수는 각각 $11\sim12$개와 $8\sim9$개로 관찰되어 수의 차이를 보였다. 반면, 살오징어는 미토콘드리아가 축사와 분리되어 mitochondrial spur를 형성하였고, 이들 spur내에는 $10\sim13$개의 미토콘드리아와 전자밀도가 높은 물질들이 밀집되어 있었다. 서해낙지, 주꾸미, 그리고 살오징어의 축사는 공히 9+2구조에 9개의 금은섬유가 둘러싸고 있었고, 살오징어의 축삭내에서만 작은 입자형의 글리코겐이 관찰되었다. 금은섬유들은 서해낙지와 살오징어에서는 꼬리의 주편까지만 관찰되었으나, 주꾸미에서는 단편에서도 관찰되었다. The mature sperms of three species of cephalopods (Octopus minar, Octopus ocellatus, Todarodes pacificus) were observed by electron microscopy. The results obtained are as follows: The sperm lengths of Octopus minor and Octopus ocellatus of octopods are long and they are about $390{\mu}m$ and $125\sim130{\mu}m$, respectively, but the sperm length of Todarodes pacificus is short and about $35{\mu}m$. The sperm of Octopus minor has a helical acrosome and a head bent a little like a banana while Octopus ocellatus of octopod has a twisted acrosome and a long rod-shaped head. A number of horizontal stripes are observed as a periodic structure in their subacrosome cavities and dense plugs are formed in the cavities of their heads. On the other hand, the acrosome of Todarodes pacificus is circular cap-shaped, and its head is long and oval. It is notable that two small cavities were observed in its basal acrosome. Juxtanuclear acrosomal materials of high electron density filled the subacrosomal cavity. In the middle piece of mature sperms of Octopus minor and Octopus ocellatus, the mitochondria form the mitochondrial sleeve, but the numbers of mitochondria differ between the species so that they are $11\sim12$ and $8\sim9$, respectively. Meanwhile, in the middle piece of mature sperms of Todarodes pacificus, the mitochondria are separated from the axoneme, forming a mitochondrial spur in which $10\sim13$ mitochondria and some electron dense materials concentrate. The axoneme of Octopus minor, Octopus ocellatus and Todarodes pacificus are of 9+2 type in common, surrounded by 9 coarse fibres. A number of glycogen were observed only in the axoneme of Todarodes pacificus. The coarse fibres were found as far as the main piece of sperm tail in Octopks minor and Todarodes pacificus, while to the end piece of sperm tail in Octopus ocellatus.

건강제언 - '노털카'와 '찡떼오스'

김상원,Kim, Sang-Won 한국건강관리협회 1997 건강소식 Vol.21 No.3