http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
김명신 ( Myoung Shin Kim ),강성민 ( Seong Min Kang ),원종현 ( Chong Hyun Won ),장성은 ( Sung Eun Chang ),이미우 ( Mi Woo Lee ),최지호 ( Jee Ho Choi ),문기찬 ( Kee Chan Moon ) 大韓皮膚科學會 2009 大韓皮膚科學會誌 Vol.47 No.11
A 68-year-old woman presented with a solitary dome-shaped papule on the right forth finger and this lesion had been developing for the past 4 months. Histopathologic examination revealed the dermal infiltration of histiocytes with foam cells and Touton-type multinucleated giant cells, which was compatible with the diagnosis of xanthogranuloma. Based on the previous reports, xanthogranuloma of the finger is quite rare, and especially in adults. Herein, we report on a case of xanthogranuloma arising on the finger of an adult. (Korean J Dermatol 2009;47(11):1318~1320)
Skin Barrier in Atopic Dermatitis
김명신 ( Myoung Shin Kim ) 한국피부장벽학회 2017 한국피부장벽학회지 Vol.19 No.1
Atopic dermatitis is a chronic inflammatory skin disease, characterized by eczematous skin lesions and pruritus. The pathogenesis of atopic dermatitis is not completely understood, yet it is now established that the defective epidermal barrier function and abnormal immune responsiveness contribute to the pathophysiology of atopic dermatitis. Traditionally, immune dysfunction leading to a Th2 cytokine imbalance, which causes skin barrier disruption, was regarded as the primary pathogenic mechanism. However, it is increasingly recognized that skin barrier dysfunction plays a critical role in the initiation and exacerbation of atopic dermatitis. Skin barrier dysfunction in atopic dermatitis is supposedly initiated by various combinations of inherited and environmental factors. In this review, we will discuss the skin barrier in the pathogenesis of atopic dermatitis and its implication in the treatment of atopic dermatitis.
Muir-Torre 증후군 유방암과 동반된 안검외 피지샘암
김명신 ( Myoung Shin Kim ),박언재 ( Oun Jae Park ),원종현 ( Chong Hyun Won ),장성은 ( Sung Eun Chang ),이미우 ( Mi Woo Lee ),최지호 ( Jee Ho Choi ),문기찬 ( Kee Chan Moon ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.8
Muir-Torre syndrome is defined by concurrent or sequential development of internal malignancy - most commonly colorectal cancer - and sebaceous neoplasm or multiple keratoacanthomas. Recent studies revealed it was caused by mutations in DNA mismatch repair genes, and suggested screening for mismatch repair gene defects may be of value for patients with Muir-Torre syndrome. We, herein, report a patient with Muir-Torre syndrome, who developed breast cancer and extra-ocular sebaceous carcinoma. In addition, we discussed our experience of immunohistochemical staining for mismatch repair protein with a review of the literature. (Korean J Dermatol 2010;48(8):696~699)
주택성능등급과 친환경건축물인증의 평가방법 비교를 통한 개선안 연구 : 환경관련등급을 중심으로
김명신(Myoung-Shin Kim),황재우(Jae-Woo Hwang),천정길(Jung-Gil Chun),하대웅(Dae-Woong Ha),박경순(Kyung-Soon Park),손원득(Won-Tug Son) 대한설비공학회 2009 대한설비공학회 학술발표대회논문집 Vol.2009 No.-
A variety of Certification systems are initiated, as increased demands for housing quality of building & house owner. New building and apartment built in Seoul metropolitan should acquire Building Energy Rating System and Housing Performance Grade indication System, Green Building Certification System. Building Energy Rating System could be acquired through the certification from energy performance index of environment grade in Housing Performance Grade Indication. Between Housing Performance Grade Indication and Green Building Certification System, There are troublesome to acquire certification because a lot of assessment items are overlapped. At a result, the rational and efficient certification system should be initiated not only to avoid overlap among those certification systems and promote Green Building market share but also efficient certification system operation. We will discuss on assessment items between Housing Performance Grade Indication System and Green Building Certification System and release the improvement method those Certification Systems to avoid overlapping to assessment items.
김명신 ( Myoung Shin Kim ),인승균 ( Seung Gyun In ),원종현 ( Chong Hyun Won ),장성은 ( Sung Eun Chang ),이미우 ( Mi Woo Lee ),최지호 ( Jee Ho Choi ),문기찬 ( Kee Chan Moon ) 대한피부과학회 2010 大韓皮膚科學會誌 Vol.48 No.5
Background: Cutaneous metastasis from an internal malignancy is uncommon and it usually arises from the breast and lung. Cutaneous metastasis from gastric cancer is rarely seen, although gastric cancer is the most common internal cancer in Korea. Objective: The purpose of this study was to analyze the clinical and histopathological characteristics of cutaneous metastasis from gastric cancer in Korea. Methods: Twenty-seven cases of cutaneous metastasis from gastric cancer were included in the study among the 14,053 patients who were diagnosed with gastric adenocarcinoma over a 20 year period. Their medical records and pathology slides were retrospectively reviewed. Results: The incidence of cutaneous metastasis was 0.19% (27/14,053). The age of the 27 patients ranged from 28 to 75, and the mean age was 53.9 with no significant difference in gender. The most frequently involved site was the abdomen followed by the face and scalp. Nodular lesion was most common (55.6%, 17/27) and inflammatory and indurated lesions were 25.9% (7/27) and 7.4% (2/27), respectively. Histopathologically, poorly differentiated adenocarcinoma (13/27) and signet-ring cell carcinoma (10/27) were common, which comprised 85.1% of the total tumor. In 7 cases (25.9%), skin lesion was the first presenting sign of gastric cancer or metastatic gastric cancer. The mean survival of the patients was 4.7 months. Conclusion: Cutaneous metastasis from gastric cancer is rare despite gastric cancer`s high prevalence as a primary cancer in Korea. It was frequently observed in patients with an advanced disease stage, yet it may represent the initial manifestation of the disease. Dermatologists can contribute to the management of patients with cutaneous metastasis by performing early detection and recognition of skin lesions. (Korean J Dermatol 2010;48(5):360~365)
레이저 시술 후 발생한 피부 장벽 손상과 자극 증상에 대한 APDDR-1001 제제 국소 도포의 효과
김명신 ( Myoung Shin Kim ),허식 ( Sik Haw ),이형민 ( Hyung Min Lee ),김정환 ( Jeong Hwan Kim ),정연수 ( Yeon Su Jeong ),신홍주 ( Hong-ju Shin ),원종현 ( Chong Hyun Won ),장성은 ( Sung Eun Chang ),이미우 ( Mi Woo Lee ),최지호 ( Je 대한피부과학회 2012 대한피부과학회지 Vol.50 No.12
Background: Because cosmetic laser treatments are getting popular, post-laser wound care becomes more important.Currently, topical moisturizers are reported to be sufficient to accelerate re-epithelialization and reduce downtime inpost-laser wound care.Objective: This study was performed to evaluate the effects of the moisturizer APDDR-1001 for post-laser woundcare, after ablative fractional laser on the face.Methods: In this double-blind, split-face study, 41 patients with photo-aged face received ablative fractional laser.They were divided into two groups, APDDR-1001 and vehicle (group 1) or control moisturizer (group 2), whichwere applied to the opposite sides of the face for 1 week after the laser treatment. The treatment efficacy wasevaluated by the transepidermal water loss (TEWL), erythema index, investigator`s assessment for recovery inerythema and overall improvement of the wound. Subjects ranked irritating symptoms and overall satisfaction ratingsin the overall improvement.Results: APDDR-1001 was well-tolerated and showed improvement in the erythema index and TEWL during the 7days of treatment. In group 2, improvement in erythema graded by investigators was significantly higher forAPDDR-1001 on day 3 (p<0.05). The overall improvement of wound ranked by investigators was significantlyhigher for APDDR-1001, compared with the controls in both groups. Subjective assessment demonstratedsignificantly less erythema (p=0.043), edema (p=0.041) and overall satisfaction ratings in the overall improvement (p<0.048) with APDDR-1001; however, no differences were detected in pain and edema between APDDR-1001 andvehicle (group 1). In group 2, subjects ranked ``much or very much improved`` in 75 % of APDDR-1001 side and55% of control moisturizer side. No significant differences in erythema, edema, pain and itching were reportedbetween APDDR-1001 and control moisturizer in group 2.Conclusion: The moisturizer APDDR-1001 demonstrated effective improvements in wound healing and subjectivesymptoms after ablative fractional laser therapy. (Korean J Dermatol 2012;50(12):1017∼1026)