불안 관련 장애의 신경생물학적 이해

김경민,김민경,이상혁,Kim, Kyung-Min,Kim, Min-Kyoung,Lee, Sang-Hyuk 대한생물정신의학회 2014 생물정신의학 Vol.21 No.4

Anxiety disorders are characterized by dysregulation of neuroendocrine, neurotransmitter and neuroanatomical functions. Substantial advances in research method offered new insights into the neurobiologic mechanisms in anxiety disorders. Advances in molecular biology have enabled illumination of hormone and neurotransmitters that have important roles in anxiety. The neuroanatomic circuits related to anxiety are also being elucidated by improvements in neuroimaging technology such as structural and functional magnetic resonance imaging. This article reviews the research data in relation to the neurobiology underlying fear and pathologic anxiety and discusses their implications for development of biological treatments for anxiety disorders.

한국과 일본의 노인장기요양보험에 관한 문헌고찰

김경민,김남희,이정화,윤현서,박혜영,김혜진,Kim, Kyung-Min,Kim, Nam-Hee,Lee, Gung-Hwa,Yoon, Hyun-Seo,Park, Hye-Young,Kim, Hye-Jin 한국치위생학회 2017 한국치위생학회지 Vol.17 No.5

Objectives: The purpose of this study is to look into the health insurance systems and application in Korea and Japan in order to improve elderly people's quality of life. Their quality of life can be improved by upgrading the long term care systems; and extending treatment and prevention. Methods: This study is to examine long term care systems articles through content analysis in the National Health Insurance Service. Data were collected from the printed Internet and analyzed. Results: A part-time dentist system in elderly care facilities has trouble in taking care of old people's oral health due to both lack of time and operational difficulties. It is urgent to arrange dental experts who can permanently stay in care facilities and to build systems which can be managed periodically and continually. Conclusions: As having staff training for the efficiency and using the manpower in care facilities (care workers), it is necessary to solve the unequal medical service in oral health care for the elderly in Korea.

연구 논문 : 전기화학적 마이크로머시닝 기술을 이용한 균일한 니오븀 표면 에칭 연구

김경민 ( Kyung Min Kim ),유현석 ( Hyeon Seok Yoo ),박지영 ( Ji Young Park ),신소운 ( So Woon Shin ),최진섭 ( Jin Sub Choi ) 한국공업화학회 2014 공업화학 Vol.25 No.1

본 연구에서는 micro-contact printing을 통하여 니오븀 호일 표면 위에 균일한 에칭 pits를 형성하였다. 균일한 보호층을 형성하고자 전해연마의 효과를 확인하였으며, 기존의 O2 플라즈마 공정 없이 손쉽게 균일한 에칭 pits를 형성시킬 수 있는 조건을 확인하였다. 메탄올 혼합 전해질을 사용하여 10 min 동안 에칭을 진행한 결과 니오븀 호일 표면 위에 지름과 간격이 각각 10 μm와 5 μm로 잘 정렬된 에칭 pits를 관찰하였다. We describe the preparation of highly-ordered etching pits on the Nb foil through a micromachining. The effects of electro-chemical polishing on the formation of uniformly-patterned protective epoxy layer was investigated. Unlike the previous proc-ess using O2 plasma, well-ordered etched pits were prepared without any dry processes. As a result, the Nb foil with the well-ordered pits of 10 μm × 5 μm could be obtained by electrochemical etching in methanolic electrolytes for 10 min.

준안정상 기반의 질화철계 영구자석소재 제조연구동향

김경민,이정구,김경태,백연경,Kim, Kyung Min,Lee, Jung-Goo,Kim, Kyung Tae,Baek, Youn-Kyoung 한국분말야금학회 2019 한국분말재료학회지 (KPMI) Vol.26 No.2

Rare earth magnets are the strongest type of permanent magnets and are integral to the high tech industry, particularly in clean energies, such as electric vehicle motors and wind turbine generators. However, the cost of rare earth materials and the imbalance in supply and demand still remain big problems to solve for permanent magnet related industries. Thus, a magnet with abundant elements and moderate magnetic performance is required to replace rare-earth magnets. Recently, $a^{{\prime}{\prime}}-Fe_{16}N_2$ has attracted considerable attention as a promising candidate for next-generation non-rare-earth permanent magnets due to its gigantic magnetization (3.23 T). Also, metastable $a^{{\prime}{\prime}}-Fe_{16}N_2$ exhibits high tetragonality (c/a = 1.1) by interstitial introduction of N atoms, leading to a high magnetocrystalline anisotropy constant ($K_1=1.0MJ/m^3$). In addition, Fe has a large amount of reserves on the Earth compared to other magnetic materials, leading to low cost of raw materials and manufacturing for industrial production. In this paper, we review the synthetic methods of metastable $a^{{\prime}{\prime}}-Fe_{16}N_2$ with film, powder and bulk form and discuss the approaches to enhance magnetocrystalline anisotropy of $a^{{\prime}{\prime}}-Fe_{16}N_2$. Future research prospects are also offered with patent trends observed thus far.

지하철 차량운용 문제에 대한 수리적 해법에 관한 연구

김경민(Kyung Min Kim),홍순흠(Soon-Heum Hong) 한국철도학회 2007 한국철도학회 학술발표대회논문집 Vol.- No.-

This paper considers subway routing problem. Given a schedule of train to be routed by a railway stock, the routing problem determines a sequence of trains while satisfying turnaround time and maintenance restrictions. Generally, the solution of routing problem is generated from set partition formulation solved by column generation method, a typical integer programming approach for train-set. However, we find the characteristics of metropolitan subway which has a simple rail network, a few end stations and 13 departure-arrival patterns. We reflect a turn-around constraint due to spatial limitations has no existence in conventional railroad. Our objective is to minimize the number of daily train-sets. In this paper, we develop two basic techniques that solve the subway routing problem in a reasonable time. In first stage, we formulate the routing problem as a Min-cost-flow problem. Then, in the second stage, we attempt to normalize the distance covered to each routes and reduce the travel distance using our heuristic approach. Applied to the current daily timetable, we could find the subway routings, which is an approximately 14% improvement on the number of train-sets reducing 15% of maximum traveling distance and 8% of the standard deviation.

초기 성 학대 경험이 있는 여성 공황장애 환자의 임상적 특성

김경민,김민경,이강수,최태규,이상혁,Kim, Kyung Min,Kim, Min-Kyoung,Lee, Kang Soo,Choi, Tai Kiu,Lee, Sang-Hyuk 대한생물정신의학회 2016 생물정신의학 Vol.23 No.4

Objectives The objective of this study is to investigate differences of clinical characteristics between a healthy female control group and female panic disorder (PD) patients with early sexual abuse history (PD+S) and without early sexual abuse history (PD-S). Methods We examined data from 83 patients diagnosed with PD and 20 healthy control subjects. We divided the patients with PD into PD+S (32 patients) and PD-S (51 patients) to compare demographic and clinical characteristics. The following instruments were applied: the Stress coping strategies, the Beck Depression Inventory (BDI), the Panic Disorder Severity Scale, the Anxiety Sensitivity Index-Revised (ASI-R), the Albany Panic and Phobia Questionnaire (APPQ) and the NEO-neuroticism. Results Compared to the PD-S, the PD+S group showed higher scores in neuroticism and the APPQ. And, in the PD+S group, the scores of neuroticism were correlated with the ASI-R and APPQ subscale scores and the APPQ total scores were associated with the scores of BDI. Conclusions This study shows that female PD+S patients have higher scores in neuroticism and the APPQ than the PD-S group, and these factors are associated with the panic-related symptoms severity. It emphasizes the need of specific strategies considering the childhood abuse history such as early sexual abuse in clinical approach among patients with PD.

들깨의 자엽절편배양을 통한 고효율 식물체 재분화

김경민,이현숙,Kim, Kyung-Min,Lee, Hyeon-Suk 한국식물생명공학회 2007 식물생명공학회지 Vol.34 No.1

들깨의 조직배양에서 배지의 생장조절제 조성은 0.1 mgyL의 NAA와 2.0 mg/L의 BA가 혼용된 배지에서 신초형성률이 24.7%로 가장 높게 나타났다. 신초형성에 적합한 배양부위는 자엽이었으며 품종별 신초형성율은 $3.0{\sim}27.3%$로 품종간 차이가 컸고, '만백들깨'의 자엽 배양에서 27.3%의 가장 높은 재분화율을 나타내었다. 조직부위별로는 공시된 모든 품종에서 배축보다는 자엽 조직에서 신초형성율이 높았으며, 신초의 분화형태는 배형성 (6.1%)보다 기관형성 (22.8%)을 경유하는 것이 많았다. A reliable and effective tissue culture system was established for Perilla frutescens (perilla) using different cultivar, explant source, and growth regulator composition in medium. MS medium supplemented with 2.0 mg/L BA and 0.1 mg/L NAA was maximum at shoot induction. Cotyledon explants formed more shoots than hypocotyl explants. The frequency of plant regeneration through organogenesis was higher (22.8%) than that (6.1%) of somatic embryogenesis. Five genotypes of perilla were screened for the feasibility of shoot regeneration, cotyledon explant of 'Manbaek' showed the highest shoot induction at a frequency of 27.3% among the tested cultivars.

DNA marker를 이용한 벼의 조직배양 효율 재선

김경민,Kim Kyung-Min 한국생명과학회 2006 생명과학회지 Vol.16 No.3

The purpose of this study is to improve the culturability of a indica type rice cultivar, IR 36, using DNA marker associated with the ability of plant regeneration in anther and seed culture. The varietal difference of ability of callus formation and plant regeneration was investigated in anther and seed culture of 8 rice cultivars. Three japonica rice cultivars showed to have better culturability than those of tongil and indica type genotypes. But two indica/japonica lines, 'MGRI 079' and 'MGRI 036', which were selected to have good culturability in previous study showed the highest regenerability (20%) in anther culture of 8 rice cultivars. Thirty four $BC_2F_4$ lines were selected by marker screening using RZ400 for 100 $BC_2F_4$ lines derived from a cross $'MGRI\;079/IR\;36^{^*3}'$. The frequency of callus formation of 30 $BC_2F_4$ lines was higher than those of 'IR 36' in anther culture of the selected $BC_2F_4$ lines. The ability of plant regeneration of 15 lines was higher than that of 'IR 36' in the seed culture of 34 $BC_2F_4$ lines. A promising line, $BC_2F_4-28$, was selected to have better culturability in the anther and seed culture of the $BC_2F_4$ lines. The heading date and grain shape of the $BC_2F_4-28$ was similar to 'IR 36'. In seed culture of 50 $BC_4F_3$ lines derived from a rice cross $'MGRI\;079/IR\;36^{^*5}'$, 11 lines including $BC_4F_3-3$ showed to have higher regenerability compared with 'IR 36'. The highest frequency of plant regeneration (11%) was obtained from $BC_4F_3-46$ in seed culture of the $BC_4F_3$ lines. 벼의 약 및 현미 배양효율과 관련된 DNA marker를 이용하여 인디카형 벼 품종인 'IR 36'의 조직배양 효율을 개선하기 위하여 실험한 결과를 요약하면 다음과 같다. MGRI집단의 약배양에서 식물체분화율이 높은 계통으로 선발된 'MGRI 079'와 'MGRI 036'의 약배양 효율은 각각 19.8%, 19.9%로 가장 높게 나타났다. 'MGRI 079'에 'IR 36'이 여교배되어 양성된 $BC_2F_4$ 100 계통에 대한 marker 검정을 실시하여 선발된 34 계통중 약배양에서 캘러스 형성률이 'IR 36'보다 높은 계통은 30계통이었고, 현미배양에서 'IR 36'보다 식물체 분화율이 높은 계통은 $BC_2F_4-28$ 외 14 계통이었다. $BC_2F_4$ 34계통 중에서 식물체분화능력이 높은 계통으로 선발된 $BC_2F_4-28$은 간장이 'IR 36'보다 큰 편이었으나 출수기와 미립특성은 'IR 36'과 비슷하였다. 'MGRI 036'에 'IR 36'을 반복친으로 여교배하여 양성된 $BC_4F_3$ 50계통의 현미배양을 실시한 결과 'IR 36'보다 식물체 재분화율이 높은 계통은 $BC_4F_3-3$ 외 10 계통이었고, 그중 $BC_4F_3-46$의 식물체 재분화율이 11%로 가장 높게 나타났다.

비콘을 활용한 통학 시스템 설계

김경민,Kim, Kyung-min 한국정보통신학회 2016 한국정보통신학회논문지 Vol.20 No.10

최근 통학버스로 인한 사고가 빈번하게 발생되고 있으며, 정부에서도 어린이 안전 종합대책을 발표하여 어린이 교통안전 취약지역에 대한 시스템을 구축할 예정이다. 학생들의 등하교시의 안전은 부모들에게 주된 관심사중 하나이다. 학교는 부모의 입장에서 학생이 무사히 학교에 도착했는지 또는 안전하게 귀가를 했는지에 대한 실시간 정보를 제공하는 체계를 가져야 할 필요가 있다. 본 논문에서는 저전력 블루투스 무선통신 장비인 비콘과 스마트폰의 GPS기능을 이용하여 학생 승하차 여부와 통학버스 위치 조회를 제공하는 통학 시스템을 제안한다. 통학 시스템은 학생들에게 제공된 비콘 UUID 정보와 통학 버스 운전자 스마트 폰 GPS 위치를 응용 앱 서버에서 수집하여 학부모와 관리자가 실시간으로 확인하도록 구성하여 학부모와 관리자가 학생 탑승 여부, 탑승시간과 버스 위치에 대해 실시간으로 정보를 확인할 수 있다. 운전자는 학생들의 탑승여부, 오탑승 여부, 운행 후 잔류학생 확인을 파악할 수 있다. The incident during commuting to school happened frequently in these days, such that the government announced the student commuting safety policy for addressing to implement the safety management system of the unsafer school commuting zone. In this paper, a commuting tracking system is proposed that notifies the location of vehicles and the boarding status of student using BLE beacon and smart phone GPS function. The commuting tracking system that gets the data from the system server of driver's smart phone GPS location and UUID of the beacon which had provided students has configured to provide notifications to parents and related administrators. It provides real-time information about whether a student boarding, boarding times and bus locations for parents and administrators. It verifies the disembarking time for each student and also provides to driver to secure if any student tries to board the wrong school bus and if any students is left behind in the bus.

폐플라스틱 잔골재의 대량 활용을 위한 무기충진재 충진

김경민,조영근,김호규,Kim, Kyung-Min,Cho, Young-Keun,Kim, Ho-Kyu 한국건설순환자원학회 2021 한국건설순환자원학회지 Vol.16 No.1