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      • Graves병에서 발생한 갑상선 암

        권수경,임동현,강상중,김성만,최영식,박요한 고신대학교(의대) 고신대학교 의과대학 학술지 2000 고신대학교 의과대학 학술지 Vol.15 No.1

        Background : Thyroid nodules in patients with Graves' disease are common and raise concern about coexistent thyroid malignancy. Furthermore, it was reported that thyroid cancers in patients with Graves' disease were more aggressive than those without. Thus, it is important to detect thyroid cancer in the patients with Graves' disease prior to surgery. However, there has been no standard guideline suggested for the management of thyroid nodules in the Graves' disease. Therefore, we tried to characterize thyroid nodules associated with Graves' disease and to assess the usefulness of ultrasonography and high resolution ultrasound-guided fine needle aspiration (FNA) in the management of thyroid nodules associated with Graves' disease. Methods : Sixty-five patients were included in the study who underwent high resolution ultrasound-guided FNA for thyroid nodules of the 341 patients with Graves' disease at Kosin Medical Center from June, 1996 to January, 1999. Thyroid nodules were classified according to the internal echo pattern, numbers and the size of nodule. Results : Thyroid nodules occurred in 19.1% of patients with Graves' disease. The age of the patients with nodules distributed evenly through third to seventh decade (18-68 years, mean 43 years). Thyroid nodules occurred evenly between third decade to seventh decade. Male to female ratio was 1:4.09. Thyroid cancers occurred in 6 patients (9.2%) of nodules, and was 1.76% of the total Graves' patients. Eight cases underwent operation. Of those 5 were papillary carcinoma and adenomatous goiter, and 1 Hurthle cell carcinoma. Malignant thyroid nodules occur evenly between third decade to seventh decade. The incidence of malignancy was 10.7% (3/28) in solitary nodule and 8.1% (3/37) in multiple nodules. Thirty-six cases (55.4%) were measured 1cm or less, 27 cases (41.4%) between 1.0cm to 3.0cm, and 2 cases (0.32%) above 3cm, and malignant nodules were 3 (11.1%), 2 (7.4%) and 1 (50.0%) respectively. The size of malignant nodule ranged between 0.5cm and 4.2cm. Three of malignant nodules were microcarcinoma (≤1cm) and the smallest one (0.5cm) metastasized to regional lymph node. Of the 65 nodules, 50 cases were solid, 4 cystic, and 11 mixed. Malignant nodules were more frequent in the solid nodule, but there was no significant difference between each group. The titers of thyrotropin binding inhibitory immunoglobulin (TBII) in the malignant patients were 9.2% to 350.0% and TBII was positive in the 4 of 6 cases of malignancy. The obtainability of adequate cytologic specimen by ultrasound-guided FNA was 95.9%. No complication except pain on aspiration site was noted during this study. Conclusion : The incidence of thyroid nodule in Graves' patients was high and the rate of malignancy also high in Graves' patients with thyroid nodule. Malignant thyroid nodules occurred relatively evenly through third to seventh decade. Large proportions of malignant nodules were microcarcinomas and even the smallest one of the malignant nodules metastasized to regional lymph node. Therefore, for the proper management of thyroid nodule associated with Graves' disease, it is suggested that ultrasonography be needed to detect thyroid nodule in all Graves' patients, and ultrasound-guided FNA be performed for the diagnosis of small thyroid cancer.

      • KCI등재

        남북산림협력 합의의제 이행을 위한 양묘장 현대화 대상지 선정 연구

        권수경,박소영 평화문제연구소 2023 統一問題硏究 Vol.35 No.2

        Inter-Korean forest and environmental cooperation has been recognized as a non-political and humanitarian field. Various previous Korean goverments has entered into agreement on this matter several times. However, the actual implementation of these agreements has faced challenges due to not only domestic but also international factors. In an era where climate change threatens the world, both north and south Korea’s collaborative endeavors, who share their land in an ecological environment, has become an important agenda linked to "2050 Carbon Neutral" and "Green Détente." One of the agenda of the 2018 Inter-Korean Forest Cooperation Sub-Conference, "Priority Promotion of Modernizing 10 Tree Nurseries," was approved for exemption from the UN sanctions on North Korea in 2019. Therefore, discussions on the target site are needed. We analyzed the current status of North Korean tree nurseries through literature and case studies such as previous governments' progress in inter-Korean forestry cooperation and the Rodong newspaper. And we presented goals for nursery modernization sites on the current status of North Korea’s deforestataion. The criteria were divided into three categories: 1) humanitarian support for natural disaster damage, 2) joint disaster prevention at the inter-Korean border, and 3) joint response to the climate crisis. This study can be quickly used as basic data for negotiations when inter-Korean forestry cooperation resumes. 남북산림·환경 협력은 비정치적이고 인도적인 분야로 인식되면서 여러 정부에서 수차례 합의가 진행되었지만 국내외 정세로 인해 실제 이행은 잘 이루어지지 않았다. 기후변화가 전 세계를 위협하고 있는 지금, 생태환경적으로 국토를 공유하고 있는 남북의 기후변화위기 공동 대응은 ‘2050 탄소중립’, ‘그린 데탕트’와 관련한 중요한 의제로 자리 잡았다. 2018년 남북산림협력 분과회담 합의의제 중 하나인 ‘양묘장 현대화 10개소 우선추진’이 2019년 유엔 대북제제 면제 승인을 받음에 따라 양묘장 현대화 대상지에 대한 논의가 필요한 상황이다. 이에 이 연구는 역대 정부의 남북산림협력 추진 경과, 노동신문 등 문헌 및 사례분석을 통해 북한 양묘장 현황을 분석하고 북한 산림황폐지 현황을 토대로 양묘장 현대화 대상지 선정을 위한 세 가지 목적을 제시하였다. 1)자연 재해 피해 우려에 따른 산림복구우선지역, 2)남북 접경지 공동 재해 예방, 3)기후위기 공동대응이 이에 해당한다. 본 연구는 남북산림협력이 재개될 때 협상의 기초자료로 신속하게 활용할 수 있을 것이다.

      • KCI등재

        산소 유량에 따른 IZO 박막의 전기적 및 광학적 특성

        권수경,이규만 한국반도체디스플레이기술학회 2013 반도체디스플레이기술학회지 Vol.12 No.4

        In this study, we have investigated the effect of the substrate temperature and oxygen flow rate on the characteristics of IZO thin films for the OLED (organic light emitting diodes) devices. For this purpose, IZO thin films were deposited by RF magnetron sputtering at room temperature and 300oC with various O2 flow rate. In order to investigate the influences of the oxygen, the flow rate of oxygen in argon mixing gas has been changed from 0.1sccm to 0.5sccm. IZO thin films deposited at room temperature show amorphous structure, whereas IZO thin films deposited at 300oC show crystalline structure having an (222) preferential orientation regardless of O2 flow rate. The electrical resistivity of IZO film increased with increasing flow rate of O2 under Ar+O2. The change of electrical resistivity with increasing flow rate of O2 was mainly interpreted in terms of the charge carrier concentration rather than the charge carrier mobility. The electrical resistivity of the amorphous-IZO films deposited at R.T. was lower than that of the crystalline-IZO thin films deposited at 300oC. The change of electrical resistivity with increasing substrate temperature was mainly interpreted in terms of the charge carrier mobility rather than the charge carrier concentration. All the films showed the average transmittance over 85% in the visible range. The current density and the luminance of OLED devices with IZO thin films deposited at room temperature in 0.1sccm O2 ambient gas are the highest amongst all other films. The optical band gap energy of IZO thin films plays a major role in OLED device performance, especially the current density and luminance.

      • 우수녹용 생산을 위한 엘크 사용

        권수경 안동대학교 농업개발원 2000 最高農業經營者課程 論文集 Vol.4 No.-

        우리 나라의 사슴 사육은 사치성, 고소득, 애완 동물 인식에서 1992년 수입개방 이후 소, 돼지, 닭 다음의 가축으로 자리를 잡아가고 있으며, 타 가축에 비해 친 환경적인 가축으로 인식되고 있다. 현재 1만여 농가에 22만여 두 사육에 이르고, 사슴 특징상 4계절이 뚜렷한 우리 나라가 사슴 사육의 최고 적지인 점을 감안 할 때 종록 개량과 품질 개선으로 수입녹용과 경쟁이 가능해 지리라고 생각된다. 세계 녹용 생산의 80%를 소비하면서 아직까지 국내생산은 20%에 불과 하고 소비에도 어려움이 있다. 원인은 여러 가지가 있겠지만 많은 양의 녹용 수입과 국산 녹용과의 가격차이로 한약 업소 및 제약회사에서 기피하는 현상으로서 막대한 외화 유출은 물론이고, 사슴 사육 농가에 부담을 주고 있다. 국내 사육 농가 규모를 보면 70%가 영세 소규모 농가이다. 앞으로 규모 확대가 이루어져야 될 것으로 생각된다. 사슴 사육 비율을 보면 꽃사슴 74% 레드디어 13.4%, 엘크 12.6% 구성되어 있는 것을 볼 때, 한약 약재화 규격에 타당한 품종은 생산성과 경제성 감안한다면, 타 품종(꽃사슴 레드디어)에 비해 녹용 생산성이 월등히 높다. 엘크의 경우 녹용성장 80일 절각에 평균 8∼9kg 생산을 하고 있으며, 회분함량과 녹용성장 일수를 비교하면 타 품종과 비교하면 월등히 낮다. 따라서, 엘크사슴으로 전환이 필요하다고 생각되며, 국내 우수 혈통의 사슴 정액 채취하여 민·관이 합동으로 인공수정 및 수정란 이식 및 종록 개량을 한다면 우수 록 보급으로 몇 년 내 외국과 품질 및 가격 경쟁이 가능하리라고 보며, 동시에 보건복지부 생약 규격집 회분함량 25% 이하 녹용과 25∼35% 이하 중품 녹용을 규격에 맞게 조지 절각으로 품질 우수한 녹용을 생산한다면, 품질 및 생산량으로 가격인하 조정을 해 한약 업소 및 제약회사에도 대량 소비체에 납품 가능하리라고 본다.

      • Graves병에서 발생한 갑상선 암

        권수경,임동현,강상중,김성만,최영식,박요한 고신대학교 의학부 2000 高神大學校 醫學部 論文集 Vol.15 No.1

        Background Thyroid nodules in patients with Graves' disease are common and raise concern about coexistent thyroid malignancy. Furthermore, it was reported that thyroid cancers in patients with Graves' disease were more aggressive than those without. Thus, it is important to detect thyroid cancer in the patients with Graves' disease prior to surgery. However, there has been no standard guideline suggested for the management of thyroid nodules in the Graves' disease. Therefore, we tried to characterize thyroid nodules associated with Graves' disease and to assess the usefulness of ultrasonography and high resolution ultrasound-guided fine needle aspiration (FNA) in the management of thyroid nodules associated with Graves' disease. Methods Sixty-five patients were included in the study who underwent high resolution ultrasound-guided FNA for thyroid nodules of the 341 patients with Graves' disease at Kosin Medical Center from June, 1996 to January, 1999. Thyroid nodules were classified according to the internal echo pattern, numbers and the size of nodule. Results Thyroid nodules occurred in 19.1% of patients with Graves' disease. The age of the patients with nodules distributed evenly through third to seventh decade (18-68 years, mean 43 years). Thyroid nodules occurred evenly between third decade seventh decade. Male to female ratio was 1:4.09. Thyroid cancers occurred in 6 patients (9.2%) of nodules, and was 1.76% of the total Graves' patients. Eight cases underwent operation. Of those 5 were papillary carcinoma and 2 adenomatous goiter, and 1 Hu¨rthle cell carcinoma. Malignant thyroid nodules occur evenly between third decade to seventh decade. The incidence of malignancy was 10.7%(3/28) in solitary nodule and 8.1%(3/37) in multiple nodules. Thirty-six cases (55.4%) were measured 1㎝ or less, 27 cases (41.4%) between 1.0㎝ to 3.0㎝, and 2 cases (0.32%) above 3㎝, and malignant nodules were 3 (11.1%), 2(7.4%), and 1 (50.0%) respectively. The size of malignant nodule ranged between 0.5㎝ and 4.2㎝. Three of malignant nodules were microcarcinoma (≤1㎝) and the smallest one (0.5㎝) metastasized to regional lymph node. Of the 65 nodules, 50 cases were solid, 4 cystic, and 11 mixed. Malignant nodules were more frequent in the solid nodule, but there was no significant difference between each group. The titers of thyrotropin binding inhibitory immunoglobulin(TBⅡ) in the malignant patients were 9.2% to 350.0% and TBⅡ was positive in the 4 of 6 cases of malignacy. The obtainability of adequate cytologic specimen by ultrasound-guided FNA was 95.9%. No complication except pain on aspiration site was noted during this study. Conclusion The incidence of thyroid nodule in Graves' patients was high and the rate of malignancy also high in Graves' patients with thyroid nodule. Malignant thyroid nodules occurred relatively evenly through third to seventh decade. Large proportions of malignant nodules were microcarcinomas and even the smallest on of the malignant nodules metastasized to regional lymph node. Therefore, for the proper management of thyroid nodule associated with Graves' disease, it is suggested that ultrasonography be needed to detect thyroid nodule in all Graves' patients, and ultrasound-guided FNA be performed for the diagnosis of small thyroid cancer.

      • KCI등재후보
      • KCI등재

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