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      • SCOPUSKCI등재

        간질감염(肝蛭感染) 및 구충제(驅蟲劑) DS-6 부작용(副作用)에 관(關)한 조사연구(調査硏究)

        곽수동,정종식,조용준,Kwak, Soo-Dong,Jyeong, Jong-Sik,Cho, Yong-Joon 대한수의학회 1983 大韓獸醫學會誌 Vol.23 No.2

        A servey on bovine fascioliasis in 52,876 cattle of Euiseong, Andong, Yecheon, Wolseong areas in Gyeongbug Province was carried out by the intradermal test, and the clinical side action of the positive cattle administered with DS-6 intramuscularly was observed. In addition pathological examination of 2 cattle died with side action of DS-6 was also conducted. The results of the studies are summarized as follows; 1. The average infestation rate of bovine fascioliasis was 31.1% and regional infestation rates were 35.1% in Eiseong, 34.5% in Yecheon, 32.2% in Andong, 26.9% in Wolseong, respectively. 2. The side actions were occurred in 1.5%(115/7,667) cf cattle administered with DS-6 and the clinical observations were salivation, dyspnea, hyperamia of conjunctiva, lacrimation, perspiration, urticaria, tremor, diarrhea, staggering, convulsion, edema and abortion. 3. Within 1 hour after the injection, side actions were occurred in 61.7% of the 115 cattle while they were observed in 37.4% of the 115 catte from 1 hour to 2 hours post injection. 4. The duration of the side action was less than 2 hours in 29.5%, 2 to 10 hours in 47.0% and more than 10 hours in 23.5% of the 115 cattle. 5. Autopsy findings and histopathological observations indicate that the death of cattle is caused by anaphylactic shock.

      • SCOPUSKCI등재

        Hog Cholera 병돈(病豚)의 뇌(腦) 및 임파장기(淋巴臟器)에 관한 병리조직학적(病理組織學的) 연구(硏究) III. 뇌염소견(腦炎所見)에 대하여

        곽수동,이차수,Kwak, Soo-Dong,Lee, Cha-Soo 대한수의학회 1982 大韓獸醫學會誌 Vol.22 No.2

        This study was undertaken to clarify the histopathological changes of pigs naturally infected with hog cholera. Microscopic observations of the brain as well as clinical observations were carried out for the naturally and experimentally infected pigs with hog cholera viruses. Electron microscopically the vascular cuffings of the brain were also observed in the experiment. In addition, clinical and pathological studios were carried out in the rabbits inoculated with ALD, lapinized and isolated strain of hog cholera virus, respectively. The results obtained are as follows; Vascular cuffing of the brain was observed in about 97% of the natural cases and all of the experimental cases. Among the 496 cuffed blood vessels of natural cases, intramural cuffing (82.9%), intramural and perivascular cuffing (11.9%) and perivascular cuffing (5.2%) were seen, respectively. Electron microscopic findings on cuffed blood vessels of the brain were endothelial cellular degeneration, intramural separation and vacuolation, perivascular vacuolation and infiltration of pleomorphic lymphoid cells. In the rabbits dosed with tissue suspension of the lymphoid organs and isolated hog cholera virus, high body temperature and vascular cuffing of the brain were observed, meanwhile these changes were more significant in pre-injected cased with indian ink.

      • SCOPUSKCI등재

        Hog Cholera 병돈(病豚)의 뇌(腦) 및 임파장기(淋巴臟器)에 관한 병리조직학적(病理組織學的) 연구(硏究) I. 임상(臨床) 및 병리해부학적(病理解剖學的) 관찰(觀察)

        곽수동,이차수,Kwak, Soo-Dong,Lee, Cha-Soo 대한수의학회 1982 大韓獸醫學會誌 Vol.22 No.1

        This study was taken to clarify the clinical signs and macroscopical lesions of pigs naturally infected with hog cholera. The clinical and macroscopical observation on the natural cases of hog cholera and experimental cases inoculated with ALD Virus and isolated virus strains were carried out. The results obtained are as follow; In clinical inspection of the natural cases, diarrhea (73.1%) blotching of ear (50.0%), staggering (42.3%), erythema of skin (40.0%), constipation (38.5%), conjunctivitis (32.7%) and dyspnea (30.8%) were observed. Dyspnea, constipation and erythema of skin were observed mainly in the experimental cases, however, staggering and conjunctivitis in pigs infected with ALD virus were found and convulsion and hemorrhage of skin of pigs infected with isolated virus were seen, respectively. The gross lesions of natural cases were hemorrhage of lymph node (82.5%), enteritis and hemorrhage of large intestine (65.0%), splenic infarction (57.5%), pneumonia (55.0%), gastritis and hemorrhage (52.5%), cardiac hemorrhage (40.0%) and renal petechiation (37.5%), while in the experimental cases, hemorrhage of lymph node, pneumonia, gastritis and hemorrhage, enteritis and hemorrhage of laryge intestine and splenic infarction were seen mainly.

      • SCOPUSKCI등재

        Hog Cholera 병돈(病豚)의 뇌(腦) 및 임파장기(淋巴臟器)에 관한 병리조직학적(病理組織學的) 연구(硏究) II. 임파장기(淋巴臟器)의 괴사(壞死)와 봉입체출현(封入體出現)

        곽수동,이차수,Kwak, Soo-Dong,Lee, Cha-Soo 대한수의학회 1982 大韓獸醫學會誌 Vol.22 No.1

        This study was taken to clarify the histopathological changes of pigs naturally infected with hog cholera. Microscopic observations of the necrotic lesion and inclusion body in the lymphoid organs were carried out in the natural cases of hog cholera and experimental cases inoculated with ALD virus and isolated virus strains. Electron microscopic findings of the intranuclear inclusion bodies in the reticular cell of spleen and lymph node were also observed in the experimental cases. The results obtained are as follow, As the histological findings necrosis of lymphoid organs was observed mainly in the lymph follicle. The necrotic lymphoid organs were found to contain 35.0% in the natural and 37.5% in the experimental cases. Intranuclear inclusion bodies were found mainly in the reticular cells of lymphoid organ, the epithelium of bronchiole and alevolus, and the vascular endothelium of brain. These inclusion bodies were seen in 40.0% of the natural cases and all of the experiment. The inclusion body was appeared to compose of activated nucleoli and chromatin granules (interchromatin and perichromatin) by electron microscopy.

      • SCOPUSKCI등재

        신생자돈의 선천성 전지과골증의 발생예

        곽수동,신종욱,최상룡,Kwak Soo-Dong,Shin Jong-Uk,Choe Sang-Yong 한국임상수의학회 1987 한국임상수의학회지 Vol.4 No.2

        Two cases of congenital hyperostosis at a pig farm were observed and examined pathologically in Landrace piglets. Twenty two piglets from 2 litters: 10 alive piglets in a litter and 2 stillborn and 10 alive piglets in another, were born with thickened forelimbs and some of them with thickened hindlimbs too. These piglets stowed symptoms of staggering and incoordination. Only one of these piglets could be reared normally and all the others died within 3 days of age. The thickened parts of their limbs were felt firm and not well pitted by finger pressing. An apparent ossification was identified on the central regions of the cross sections of the thickened limbs, and some pale, gray and ossiferous signs were found in the peripheral soft areas. On histopathological examination of the thickened limbs, it was found that the bone trabeculae were newly proliferated in a concentric form in central regions and in a radiated form in peripheral regions. The peripheral regions of the periosteum and perichondrium of new bone were proliferated with connective tissue and the edematous muscle bundles were atrophic and degenerative. Both the sows which produced piglets of congenital hyperostosis were mated with a different boar at next breeding and farrowed normal piglets. It was concluded that the swine congenital hyperostosis in the present cases was expressed by autosomal recessive gene of first mating boar.

      • SCOPUSKCI등재

        임신돈(姙娠豚)에서 관찰(觀察)된 Nephroblastoma

        곽수동,이춘식,조용준,이차수,한두석,Kwak, Soo-Dong,Lee, Choon-Sik,Cho, Yong-Joon,Lee, Cha Soo,Han, Du-Seik 대한수의학회 1982 大韓獸醫學會誌 Vol.22 No.1

        This paper dealt with histopathological observations of the nephroblastoma in the pregnant pig died on 8 days before paturation day. The results summarized as follows: Authors considered that in necropsy finding the pregnant pig died of circulative and respiratory disturbance by compression of fetus and renal tumor weighing about 12Kg. In microscopical findings of the renal tumor it was composed of well differentiated tumor cells and connective tissue elements. As differentiation of the neoplastic epithelial cells progressed, tubular and cystic structures, and papillary structures resembled to glomeruli appeared. This tumor was regarded as nephrohlastoma.

      • SCOPUSKCI등재

        한국재래산양의 Listeria병에 관한 임상 및 병리조직학적 연구

        곽수동,여상건,Kwak Soo-Dong,Yeo Sang-Geon 한국임상수의학회 1988 한국임상수의학회지 Vol.5 No.1

        These studies were taken experimentally to clarify the clinical and histopathological findings of listeriosis in Korean native goat(KNC). Four KNGs of 4 to 5 months of age were inoculated orally or in-travenously (IV) with Listeria monocytogenes isolated from a field case of KNG. 1. On the clinical findings, depression, anorexia and fever were observed in all inoculated goats, and nasal discharge, keratoconjunctivitis and diarrhea in 3 of 4 goats. Highest rectal temperature after in-oculation was 2.5$^{\circ}C$ higher in IV inoculated goats and 1.9$^{\circ}C$ higher in orally inoculated than normal rectal temperature observed before inoculation. Durations of clinical course after inoculation in IV and orally inoculated goats were 5 days and 8 days, respectively. 2. On the gross lesions, swelling of the lymph nodes, hemorrhage and .inflammation of the small intestine and rigor mortis were observed in 4 of 4 goats, and keratoconjunctivitis, hemorrhage and inflammation of the large intestine, swelling of the spleen, pneumonia and hydropericardium in 3 of 4 goats. Congestion of the visceral organs and ecchymosis of the sin in a fetus were observed. Keratoconjunctivitis, hemorrhage of the abomasum, swelling of the lymph node, hemorrhage and inflammation of the small intestine, swelling of the spleen, necrosis of the liver and pneumonia were observed as severe lesions. These lesions were more severe in IV inoculated goats than those in orally inoculated goats. 3. On histopathological findings, focal necrosis found throughout the livers occurred mainly on peripheral areas of hepatic lobules. These necrotic foci consisted of neutrophils, lymphocytes, macrophages, short rod bacteria and necretic hepatic cells. Suppurative pneumonia of the lung, hyperemia, congestion, epithelial necrosis and sloughing of the small and large intestine, swelling in periventricular regions of the central nervous system, swelling of the kidney, spleen and lymph node were observed as listerial lesions.

      • 도축돈의 대소장에 병리조직학적 변화에 관한 관찰

        곽수동,Kwak Soo-dong 대한수의사회 1986 대한수의사회지 Vol.22 No.4

        The present study was carried out to observe the histopathological changes of the intestinal structures of slaughtered pigs at the abattoir of Jinjoo city. The tissue samples of the ileum and cecum were taken from 114 slaughtered pigs in four seasons. The

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