산전 진단된 수신증에 동반된 선천성 기형 및 염색체 이상

곽나현 ( Na Hyun Kwak ),한성우 ( Sung Woo Han ),정지미 ( Ji Mi Jung ),전가원 ( Ga Won Jeon ),신종범 ( Jong Beom Sin ) 대한주산의학회 2009 Perinatology Vol.20 No.4

목적: 산전 초음파의 발달로 수신증의 발견 빈도는 증가하고 있으며 진단시기는 점점 빨라지고 있으나, 검사지침이나 자연경과, 치료방침과 대한 명확한 지침은 부족한 실정이다. 저자들은 수신증으로 진단받는 신생아들에 동반된 선천성 기형의 종류와 염색체 이상에 대해 알아 봄으로써 출생 후 환자관리에 도움이 되고자 하였다. 방법: 2000년 1월부터 2008년 12월까지 산전 초음파에서 수신증이 발견되어 인제대 부산백병원에서 출생 후 3일 이후 1개월 이내 초음파 검사에서 수신증으로 진단된 297명, 381 신단위를 대상으로 의무기록을 후향적으로 분석하였다. 초음파소견에서 신우의 전후 길이가 5mm 이상인 경우를 수신증으로 정의하였고, The Society for Fetal Urology (SFU)의 기준에 따라 분류하여 수신증의 정도에 따라 동반 기형 및 염색체 이상의 종류 및 빈도를 알아보았다. 결과: 염색체이상의 빈도는 297예 중 31예(11%)였으며, trisomy 15예, deletion 8예, duplication 2예, 성염색체 이상 4예 이었으며, 가장 흔한 염색체 이상은 21 Trisomy, Turners syndrome, 상염색체 결실 순이었다. 수신증의 빈도와 달리 염색체 이상은 여아에서 남아보다 빈도가 2배 정도 높았으며, 일측성과 양측성 수신증에서 염색체 이상의 빈도 차이는 없었다. 동반된 기형은 요로생식기 기형이 46.5%, 심혈관계 기형이 22.8%, 소화기계 기형이 10.2% 중추신경계 기형이 11.1%, 안면기형이 7.1%, 기타 기형이 2.3%를 차지하였다. 수신증으로 진단받은 신생아 중, SFU Grade 3, 4인 중등도 이상의 수신증일수록 선천성 기형이 동반된 빈도가 높았으며, 동반된 기형의 수가 많을수록 염색체 이상의 빈도가 높았다. 결론: 수신증이 있는 신생아에서는 요로생식계 및 위장관계 기형에 대한 면밀한 방사선 검사 및 신체검사가 필요하며, 특히 동반된 기형이 발견된 경우에는 염색체 검사도 시행하는 것이 분만 후 신생아 관리에 도움이 될 것이다. Purpose: With the increasing use of antenatal sonography, fetal hydronephrosis has been reported more frequently. But, despite extensive clinical and scientific research much controversy still exists about the assessment and management of hydronephrosis. We performed a retrospective study to determine the frequency of associated malformations and chromosomal defects in prenatally diagnosed hydronephrosis. Methods: The records of 297 neonates who were diagnosed with hydronephrosis through antenatal ultrasonographic screening, were retrospectively analyzed. They were confirmed at 3 days to 1 month after birth with postnatal ultrasonography in Busan Paik Hospital, between January 2000 and December 2008. We karyotyped 297 neonates after ultrasonographic examination revealed hydronephrosis and malformations. Results: Chromosomal abnormalities were detected in 31 (11%) cases of 297 cases and more common in female than male. The commonest chromosomal abnormality was trisomy 21, followed by Turner syndrome, deletion of autosome, unbalanced translocation. 127 cases in 109 infants had associated malformations such as urogenital and cardiovascular and gastrointestinal anomalies. The associated malformations were more common in moderate to severe hydronephrosis than mild and the number of additional abnormalities increased with the chromosomal defects. Conclusion: Particular attention should be paid for the cases in congenital hydronephrosis with any associated malformation such as urogenital and cardiac malformation, to investigate chromosomal abnormalities. This will enable clinicians to establish appropriate management and postnatal care.

하악골에 발생한 선천성 치은종 1례

곽나현 ( Na Hyun Kwak ),정지미 ( Ji Mi Jung ),전가원 ( Ga Won Jeon ),신종범 ( Jong Beom Sin ) 대한주산의학회 2009 Perinatology Vol.20 No.2

Congenital epulis is a rare benign tumor occurring on the anterior maxillary gingiva, also known as granular cell tumor of the newborn or Neumann`s tumor, which is seen only in the newborn and is different from other granular cell tumors. Congenital epulis occurs exclusively in female newborns eight to ten fold higher than in males. It can protrude out of the newborn`s mouth to prevent normal closure of mouth and interfere with respiration or feeding. The treatment of choice for large symptomatic epulis is simple surgical resection. Wide surgical excision is not required, because no recurrences have been reported. This report describes a case of congenital epulis occurring on the mandibular gingiva, and typical immunohistochemical stain findings.

온라인 음식배달 플랫폼의 배달요금 부과정책이 소비자의 공정성 지각에 미치는 영향

이효정,곽나현,이충훈 한국유통경영학회 2022 유통경영학회지 Vol.25 No.1

Purpose: The primary purpose of this study is to examine the relationship between various types of the food delivery charge and the customers’ perceived fairness on the charge required by the online-to-offline (O2O) food delivery platform. In particular, it attempts to understand how fair customers perceive the food delivery charges to be and further to identify the rational condition in which the customers find the delivery charge to be fair in the O2O food delivery platform. Research design, data, and methodology: A 2(Delivery charge by distance) x 2(Delivery charge by weekend/holiday) x 2(Minimum order amount) betweensubjects factorial design experiment was conducted in which the total of 326 subjects were invited and randomly assigned to one of the eight experimental conditions through an online survey panel data company. A three-way analysis of variance (ANOVA) was mainly performed to test the proposed research hypotheses. Results: The result showed that customers find delivery charge by distance or weekend/holiday to be unfairer than any other type. In contrast, they are more likely and willing to accept the delivery charge contingent upon the minimum order charge. Additionally, we found that when the delivery charge type is combined with weekend/holiday charge requirement, the customer’s perceived fairness on the delivery charge significantly decreases in a negative direction. Implications: This study provided empirical evidence to the O2O food delivery platform s e rvice and d elive ry f ood marke te r in t hat t he rate fe nce strate gy and delivery charges should be specified at a reasonable and acceptable degree for customers. Additionally, this study paves the way for further empirical research into policy making for food delivery charge as it explores the causal relationship between various types of the food delivery charge and the customers’ perceived fairness on the charges.

사춘기 전후 흰쥐 난소 및 난관의 현미경적 관찰

유태경,김진희,김형은,곽나현,이연주,정유진,김완종 순천향대학교 기초과학연구소 2014 순천향자연과학연구 논문집 Vol.20 No.2

The objective of this study is to observe and compare the morphology of female genital organs such as ovary and oviduct in premature and mature rats. Female Sprague-Dawley rats were divided into two groups; premature(2 weeks of age) and mature(8 weeks of age). Rats were anesthetized with ethyl ether and female genital organs were removed. Light microscope specimens were prepared by routine method: fixed in 10% formalin, embedded in paraffin block, cut with a microtome, and stained by hematoxylin and eosin. In the case of premature rats, there were primitive, primary and growing follicles, but not any corpus luteum in the ovary. And oviduct showed the simple structure composing less developed mucosa, submucosa, muscle and serosa. In the case of mature rats, however, various stages of developing follicles and corpus luteum could be seen in the ovary. Particularly, Graafian follicles at the periphery and corpus luteum at the medulla were present in the same time. Mature oviduct was characterized by folded villi, thick mucosa and plentiful blood vessels. On conclusion, structural and functional differentiation of female genital organs such as ovary and oviduct is correlated with gonadotropins at puberty.

COVID-19 팬데믹 상황에서 간호대학생의 교수-학생 상호작용, 심리적 안녕감, 간호사 이미지와 간호전문직관의 관계

박진호(Park, Jinho),강다윤(Kang, Dayun),강지민(Kang, Jimin),곽나현(Gwak, Nahyeon),김채은(Kim, Chaeeun),이명경(Lee, Myung Kyung) 한국간호교육학회 2022 한국간호교육학회지 Vol.28 No.1

Purpose: The purpose of this study was to investigate the association of faculty-student interaction, psychological well-being, and the image of nurses with nursing professionalism in the COVID-19 pandemic situation. Methods: The participants of the study were 243 nursing college students located in Daegu, Kyungpook. Data collection was performed between August 11 and 20, 2021. Data were analyzed with descriptive statistics, independent t-test, ANOVA, Pearson’s correlation coefficient, and stepwise multiple regression using the IBM SPSS 21.0 program. Results: The multiple regression showed that nursing professionalism was associated with a positive image of nurses (β=.71, p<.001) and higher faculty-student interaction (β=.11, p=.023). Additionally, a negative impression about nurses during the COVID-19 pandemic was negatively associated with nursing professionalism (β=-.12, p=.003). The explanatory power of the factors was 67 percent of the total variances on nursing professionalism; however, psychological well-being was not an associated factor. Conclusion: This study suggested that, to improve nursing student’s nursing professionalism in the COVID-19 pandemic situation, nursing colleges should systemize curricular and non-curricular programs to improve awareness of nurses’ efforts and faculty-student interaction.