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구면/비구면 레스토렌즈와 크리스타렌즈를 삽입한 후의 시력, 구면수차, 대비감도의 비교
강의천,김응권,김태임 대한안과학회 2011 대한안과학회지 Vol.52 No.11
Purpose: To assess visual acuity, spherical aberration and contrast sensitivity in patients who were implanted with spheric, aspheric ReSTOR? or Crystalens HD? lenses. Methods: The present study enrolled 16 patients (32 eyes) implanted with biliateral spheric ReSTOR? (four patients, spheric ReSTOR group), bilateral aspheric ReSTOR? (seven patients, aspheric ReSTOR group) or bilateral Crystalens HD? (five patients, Crystalens HD group) lenses. At three months postoperatively, visual acuity, spherical aberration, and contrast sensitivity were evaluated. Results: Three months after surgery, there were no significant differences in uncorrected distant or intermediate visual acuity among the three groups. Uncorrected near visual acuity in the spheric and aspheric ReSTOR groups was superior to that in the Crystalens HD group, and the aspheric ReSTOR group had less spherical aberration. Mesopic contrast sensitivity in the Crystalens HD group was significantly higher at three cycles per degree compared to those in the spheric and aspheric ReSTOR groups. Conclusions: Uncorrected near visual acuity in the Crystalens HD group was inferior to those in the spheric and aspheric ReSTOR groups, but the mesopic contrast sensitivity of the Crystalens HD group at three cycles per degree was superior to those in the spheric and aspheric ReSTOR groups. J Korean Ophthalmol Soc 2011;52(11):1275-1280
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이규호,강의천,고형준 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.2
Purpose: To evaluate the prognostic factors and outcomes of dexamethasone intravitreal implant (DEX implant)for intravitreal bevacizumab refractory macular edema secondary to branch retinal vein occlusion (BRVO). Methods: This was a retrospective, interventional case series. Medical records were reviewed, and a total of38 eyes that were treated with DEX implant for macular edema secondary to BRVO that did not respond toat least two consecutive intravitreal bevacizumab injections (IBIs) were included. Best-corrected visual acuity(BCVA), central subfield macular thickness, and central subfoveal choroidal thickness were evaluated at baseline,2 months, and 6 months after DEX implantation. Results: Patients had undergone an average of 6.32 ± 4.66 prior IBI treatments. The average BCVA improvedfrom 0.53 ± 0.26 to 0.41 ± 0.25 and 0.44 ± 0.23 logarithm of the minimal angle of resolution (logMAR) at 2 and6 months, respectively (p < 0.001). The average central subfield macular thickness was 504.00 ± 121.54 μmat baseline and changed to 293.21 ± 74.17 μm and 427.28 ± 119.57 μm at 2 and 6 months, respectively (p <0.001 and p = 0.002). Average central subfoveal choroidal thickness was 237.46 ± 92.21 μm at baseline andchanged to 204.75 ± 74.74 μm and 226.86 ± 90.77 μm at 2 and 6 months, respectively (p < 0.001 and p = 0.455). Twenty-two eyes (58%) gained ≥0.1 logMAR at 2 months, while 16 eyes showed no improvement. Low BCVAat symptom presentation, low baseline BCVA, and shorter duration of macular edema were correlated withincreased BCVA after treatment. Conclusions: The DEX implant improves functional and anatomical outcomes for up to 6 months in about halfof the patients treated with IBI refractory macular edema secondary to BRVO, particularly in patients with lowinitial and baseline BCVA.
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이규호,고형준,강의천 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.3
This report describes a case of angiographically documented foveal avascular zone (FAZ) enlargement after a single intravitreal injection of bevacizumab for macular edema secondary to central retinal vein occlusion (CRVO). A 71-year-old female was treatedwith an intravitreal bevacizumab injection for macular edema following CRVO. Despite successfully decreased edema one month after injection, the postinjection best-corrected visual acuity immediately decreased from 20/40 to 20/1000 (Snellen equivalent). The FAZ area increased from 0.37 mm2 to 3.11 mm2 (8.4-fold increase). While intravitreal anti-vascular endothelial growth factor is effective and should be considered as a first-line treatment for macular edema secondary to CRVO, it may aggravatemacular ischemia.
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Drug Attitude and Adherence to Anti-Glaucoma Medication
홍사민,강성용,윤종욱,강의천,성공제,김찬윤 연세대학교의과대학 2010 Yonsei medical journal Vol.51 No.2
Purpose: The purpose of this study is to assess patient attitudes towards anti-glaucoma medication and their association with adherence, visual quality of life, and personality traits. Materials and Methods: One hundred and forty-seven glaucoma patients were enrolled this study. The participants were divided into ‘pharmacophobic’ and ‘pharmacophilic’ groups according to their scores on the Modified Glaucoma Drug Attitude Inventory (MG-DAI). To establish a correlation with patient drug attitude, each group had their subjective drug adherence, visual quality of life, and personality traits examined. For personality traits, the Myers-Briggs Type Indicator (MBTI) was used to sub-classify each group. Results: Among the patients analyzed, 91 (72.80%) patients showed a ‘pharmacophobic’attitude and 34 (27.20%) patients showed a ‘pharmacophilic’ attitude. The pharmacophobic group tended to have worse adherence than the pharmacophilic group. Personality dichotomies from the MBTI also showed different patterns for each group. Conclusion: In glaucoma patients, pharmacological adherence was influenced by their attitude towards drugs; an association might exist between drug attitude and underlying personality traits.
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이규호,김서희,이지민,강의천,고형준 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.5
Purpose: To investigate the peripapillary choroidal thickness (PCT) of polypoidal choroidal vasculopathy (PCV)and exudative age-related macular degeneration (AMD) and to evaluate their responses to anti-vascular endothelialgrowth factor (VEGF). Methods: Thirty eyes with PCV and 25 eyes with exudative AMD who were treatment naïve were included inthis study. PCT and subfoveal choroidal thickness were evaluated both before and after intravitreal anti-VEGF. Results: The initial mean PCT of PCV (153.78 ± 56.23 μm) was thicker than that of exudative AMD (88.77 ±23.11 μm, p < 0.001). Temporal, superior, nasal, and inferior PCTs of PCV were all thicker than those observedin exudative AMD (all p < 0.05). After anti-VEGF, the mean PCT of PCV was significantly reduced (134.17 ±41.66 μm, p < 0.001), but the same was not true not in exudative AMD (86.87 ± 22.54 μm, p = 0.392). PCTshowed a similar tendency in all quadrants. Conclusions: PCV exhibits a thick choroid in the peripapillary region. PCT decreases after anti-VEGF in PCVbut not in exudative AMD. In exudative AMD, subfoveal choroidal thickness decreased, but that in the peripapillaryregion did not.
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