http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
강성귀 대한신장학회 1984 Kidney Research and Clinical Practice Vol.3 No.2
The present study is an investigation of the mechanism of changes in erythrocyte 2, 3-dipho- sphoglyceric acid(2,3-DPG) in patients with chro- nic renal failuze during hemod-ialysis. The study was conducted in 7 Korean and 6 American patie nts on maintenance hemodialysis. Plasma and erythrocyte pH measured in Korean patients increase from 7. 31±0. 02 and 7. 13±0.02 before hemodialysis to 7.40±0.04 and 7.20±0.03 after hemodialysis(p$lt;0. 001). Hemoglobin 2,3-DPG increased from 10. 862. 89 pmol/gm before hemodialysis to 19. 93±2. 89 pmol/ gm after hemodialysis(p$lt;0. 001) in Korean patients. Similary hemoglobin 2,3-DPG increased with nemodialysis from 12. 54±2. 53 pmol/gm to 18. 7E/ 6. 73 pmol/gm in 6 American patients. Blood glucose increased from 93. 3±8. 5 mg/dl before hemodialysis to 117. 1 ±6. 1 mg/dlafter hemodialysis in Korean patients. However, blood glucose concentration did not change signifieantly with hemodialysis in American patients. Despite sulstantial anemia, l:emoglobin 2,3-DPG priordialysis was significantly lower than the values obtaiaed in the normal controls(17. 45±4. 28 mmol/gm). The increase in blood glucose with hemodialy:is obaerved in Korean patients was probably attributable to the lower baseline glucose concentration and tle gain of glucese from dialysate, which had a glu- co e coneentration of 186.1±34.1 mg/dl. The results suggest that the ir.crease in 2,3-DFG with hemodialyeis is probably caused by inqrease in pH and inereased glueoee utilization.