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다발성 각화 극세포종이 선행된 급성 발열성 호중구성 피부병
임철완(Chull Wan Ihm),강광영(Kwang Young Kang),김순철(Soon Cheol Kim),전택환(Taek Hwan Jun) 대한피부과학회 1999 대한피부과학회지 Vol.37 No.9
Severe recurrent attacks of acute febrile neutrophilic dermatosis shortly followed multiple keratoacanthoma in a 43-yaear-old man with myelodysplastic syndrome. Besides the typical clinicopathological findings of the syndrome(fever, leukocytosis and neutrophilic erythematous plaques of the skin), the patient showed orolingual and conjunctival ulceration and severe cutaneous pathergic reactions. Moreover, to the best of our knowledge, multiple keratoacanthoma has not yet been reported with relation to the acute febrile neutrophilic dermatosis. (Korean J Dermatol 1999;37(9) : 1310∼1315)
Trichophyton rubrum에 의한 유아 피부사상균증 2예
김한욱,강광영,강성호 대한의진균학회 1997 대한의진균학회지 Vol.2 No.1
Dermatophytoses of newborn infants are known to be very unusual, although cutaneous candidosis in infancy is relatively common. We report two cases of dermatophytoses seen in a 33-day-old infant and a 63-day-old infant. The dorsum of the foot of the former showed an annular lesion with crusty border of about 3 weeks duration and the chin of the latter showed an annular lesion with intensely inflamed border of about 5 weeks duration. From the two patients, Trichopyton rubrum was isolated. The articles describing dermatophytoses in infancy in the Korean literature did not report any cases similar to ours.
김한욱,강광영 대한의진균학회 1998 대한의진균학회지 Vol.3 No.1
Microsporum canis is known to be the main causative agent of tinea capitis and tinea corporis in children. Contrary to Trichophyton rubrum and Trichophyton mentagrophytes var. interdigitale, it very rarely infects the nail. In the reported cases of tinea unguium due to Microsporum canis, fingernails were usually affected. We report a patient with tinea unguium of thumb and big toe nails caused by Microsporum canis.
혈액 투석 중인 만성 신부전증 환자에서 소양증과 호산구증다증의 연관성
박성광,임철완,이준상,문치영,강광영,유민영 대한신장학회 1999 Kidney Research and Clinical Practice Vol.18 No.4
Background:Pruritus is one of the most common complaints of patients with chronic renal failure undergoing hemodialysis. But its etiology is not clear, and there is no universally effective treatment. Recently we have experienced eosinophilia in hemodialysis patients suffering from pruritus. Objective:The purpose of the this study was to evaluate the relationship between pruritus and eosinophilia in patients on hemodialysis. Methods:We examined degree of pruritus and eosinophilia in 65 patients with end stage renal disease who were on hemodialysis from September 1996 to August 1997 in artificial kidney center of Chonbuk National University Hospital. The study was conducted by means of personal interview, physical examination, and review of medical records. The degree of pruritus was measured by scores from minimal 0 point to maximal 48 points and more than 5% or 500/mm3 eosinophils in peripheral blood was regarded as eosinophilia. Results: 1)Incidence of each cutaneous symptoms were pruritus(61.5%), xerosis(35.4%), hyperpigmentation (30.8%), easy bruising(16.9%), nail change(12.3%), decreasing in sweating(10.8%), hypotrichosis(7.7%), and acne(4.6%). 2)Forty(61.5%) of 65 patients undergoing hemodialysis had pruritus, 32.3% in mild, 20% in moderate, and 9.2% in severe degree by pruritus score. 3)Nineteen(29.2%) of the 65 patients had eosinophilia:23.8%(5/21) of patients with mild pruritus, 30.7%(4/13) of patients with moderate pruritus, and 66.7%(4/6) of severe pruritus. It could be said that prevalence of eosinophilia was related to the severity of pruritus. 4)With repeated hemodialysis the severity of pruritus increased in 65%(26/40), decreased in 22.5% (9/40), did not change in 12.5%(5/40) of patients with pruritus. 5)Pruritus was not related to the serum calcium (Ca), inorganic phosphorus(PO4), CaXPO4 product, BUN, or creatinine. There was, however, significant correlations with the serum alkaline phohphatase. Conclusion:There was a positive correlation between the prevalence of eosinophilia and severiy of pruritus in patients on hemodialysis.