http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
항거식세포혈청(AMS) 및 항임파구혈청(ALS)이 망상내피계(RES)에 미치는 영향
金周德,金世鍾,金駿杰 최신의학사 1975 最新醫學 Vol.18 No.1
In recent years in vivo and in vitro properties of anti-macrophage serum(AMS) and anti-lymphocyte serum (ALS) have been widely studied by many investigators. Heterologous ALS has potent immunosuppressive activities for both cellular and humoral immune responses. The immunosuppressive activities of the heterologous AMS are controversial at present, but the phagocytic characteristics of peritoneal macrophages are affected by the AMS. However, the mechanisms by which AMS and ALS exert their activities are still unresolved. The present study was undertaken to evaluate the cross-reactivities in cytotoxic tests and the effect of AMS and ALS on the carbon clearance of reticuloendothelial system of chipmunk. In in vitro cytotoxic tests, AMS was not specific for macrophages, and ALS not for lymphocytes; AMS cross-reacted and was cytotoxic to lymphocytes, and ALS to macrophages. Clearance of colloidal carbon from peripheral blood of chipmunk was impaired by intraperitoneal injection of AMS or ALS.
김주덕,김주원,궁석강,강준홍,신혜영,김두식,류시정,김경한 고신대학교(의대) 고신대학교 의과대학 학술지 2017 고신대학교 의과대학 학술지 Vol.32 No.1
Objectives : Propofol, midazolam and remifentanil are commonly used for clinical anesthesia. We compared the effects of midazolam-propofol-remifentanil and propofol-remifentanil on hemodynamic responses during anesthesia induction in hypertensive patients. Methods : Seventy-six hypertensive patients with ASA II-III were assigned to receive midazolam-propofol (group MP; n = 38) or propofol (group P; n = 38). Anesthesia was induced with midazolam 0.03 mg/kg (group MP) or saline 0.03 ml/kg (group P). After two minutes, propofol 1.0 mg/kg (group MP) or 1.5 mg/kg (group P) i.v. bolus was administered. Simultaneously, 4 ng/ml of remifentanil target controlled infusion (TCI) was administered in both groups. Anesthesia was maintained using sevoflurane and 2 ng/ml of remifentanil TCI. Systolic, diastolic, and mean blood pressure (SBP, DBP, and MBP) and heart rate (HR) were measured before induction, 2 min after midazolam or normal saline, 2 min after propofol, 1 min after rocuronium, and immediately, 1 min, 2 min, and 3 min after intubation. Results : SBP, DBP, and MBP decreased after propofol administration and increased immediately after intubation in both groups (P < 0.05). After intubation, SBP, DBP, and MBP decreased more than baseline values in either group. Although the overall BP of Group P was lower than that of Group MP, there were no significant differences except for SBP at 2min after intubation (P < 0.05). HR was no significant difference in either group. Conclusion : Our results suggest that midazolam-propofol-remifentanil has similar hemodynamic effect with propofol-remifentanil during anesthesia induction in hypertensive patients.
김주덕,이정길,김상수,신혜영 고신대학교(의대) 고신대학교 의과대학 학술지 2014 고신대학교 의과대학 학술지 Vol.29 No.1
Spinal cord stimulation (SCS) is a reliable clinical option for treatment of refractory chronic pain. It is known to be effective method for treating sympathetic pain, failed back surgery syndrome, and complex regional pain syndrome etc. The devices and implantation techniques for SCS are already highly developed and continuously improving, but there are some complications that can not be corrected easily. Lead migration is the most common complication after SCS. It can cause failure of SCS that can make discomfort to patients. Here we describe our experience of lead migration in implanted SCS which was inserted to a patient with complex regional pain syndrome patient.