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Cefoperazone이 호중구의 식균작용에 미치는 영향 : Preliminary Study
김성경,강문원,이용준,신완식,윤호중,정희영 대한감염학회 1987 감염 Vol.19 No.1
We studied the effect on phagocytic function of human neutrophils using cefoperazone with direct and indirect contact methods. The effect was measured by counting the number of engulfed S. aureus by microscopy. Phagocytosis was enhanced at all concentrations (0.05 ug/ml - 100 ug/ml) and was maximal at concentration of 0.1 ug/ml in both methods (about 2 times that of the control). For successful treatment of intractable infections which are frequent in neutropenic hosts, it is logical to choose drugs potentiation the various defense mechanisms in addition to antibiotic therapy.