Utility of Global Strain by Two-Dimensional and Three-Dimensional Speckle Tracking for Assessing Left Ventricular Diastolic Function: Comparison with Pressure Wire Analysis

신성희,박상돈,우성일,김대혁,박금수,권준 대한심장학회 2013 Korean Circulation Journal Vol.43 No.9

Background and Objectives: We evaluated the utility of two-dimensional (2D) and three-dimensional (3D) left ventricular (LV) global myocardial deformity parameters for assessing LV diastolic function by comparing invasive measures of LV performance. Subjects and Methods: Echocardiography and LV pressure were assessed in 39 patients. Myocardial LV longitudinal, circumferential, and radial deformations, as well as area strain, were evaluated utilizing 2D and 3D speckle tracking software. The 2D early diastolic strain rate (2D-SRe) was measured from the 3 apical and 3 short axis views. The 3D diastolic index (3D-DI) was calculated by the % change of global strain during the first one-third of the diastolic period. LV end diastolic pressure (LVEDP) and the rate of LV pressure change (dP/dt) were collected using a pressure-conducted catheter and tau was calculated. Results: dP/dt min were related to early mitral annular velocity (e’), 2D-SRe long, 2D-SRe radial , as well as 3D-DI long , and 3D-DI as . Additionally, LVEDP was associated with the ratio of mitral early diastolic velocity (E) to 2D-SRe long , 2D-SRe circ , 2D-SRe radial , 3D-DI long , 3D-DI circ , and 3D-DI as . E/2D-SRe long , E/2D-SRe radial , E/3D-DI long , and E/3D-DI as were comparable with E/e’ in predicting patients with elevated LVEDP. Among those patients with E/e’ of 8 to 15, E/3D-DI long provided incremental value in identifying those with LVEDP ≥15 mm Hg. Conclusion: 2D-SRe long , 2D-SRe radial , 3D-DI long , and 3D-DI as were related to LV relaxation, and the ratios of E to those parameters were asso-ciated with LVEDP. In addition, among patients with indeterminate E/e’, E/3D-DI long offered incremental value in predicting elevated LVEDP, suggesting it may provide supplementary information in the evaluation of LV diastolic function.

혁신도시의 장소구축과 도시 이미지

신성희 대한지리학회 2007 대한지리학회 컨퍼런스 자료집 Vol.1 No.-

분리장소에 따른 황색 포도구균의 철흡수기전의 활성

신성희,임용,김진호 대한감염학회 2002 Infection and Chemotherapy Vol.34 No.1

최근 광주지역에서 분리된 황색포도상구균의 항생제 내성

신성희,장정수,임용 조선대학교 2000 The Medical Journal of Chosun University Vol.25 No.2

본 연구를 통해 얻어진 연구결과를 요약하면 광주지방에서 분리된 황색포도상구균의 항생제 내성율은 AMXCCV, CPFX, CLM, EM, GM, OXAC, PCV, SXT, VM, CTX, IMPM에 대해 각각 61.0, 65.3, 50.0, 76.5, 76.6, 66.9, 96.7, 15.6, 0, 87.5, 95.5%로 조사되었다. 각각의 항생제에 대해 내성을 보이는 균과 감수성을 보이는 균으로 양분한 다음 다른 항생제들에 대한 감수성 정도를 조사한 결과에 의하면 각각의 항생제에 대해 내성을 보이는 균들은 감수성을 보이는 균들에 비해 다른 항생제에 대해서도 감수성이 낮았다. MRSA는 약 67%로 비교적 높은 비율로 분리되었으나 최근 5년 동안 비율이 크게 변화되지 않았다. MRSA는 사용한 항생제 중 SXT와 VM에 대해서만 높은 감수성을 보였을 뿐 효과가 있는 것으로 알려졌던 다른 항생제들에 대해서는 높은 내성율을 보였다. Objectives : The emergence of Staphylococcus aureus showing multi-drug resistance emphasizes the importance of the prudent use of antibiotics. To survey and obtain the basic information for reappraisal of practical usefulness, we investigated the profiles of antimicrobial resistance of S. aureus isolated recently in Gwangju area. Materials and Methods : S. aureus was isolated from community-hospitals in Gwangju and finally identified by coagulase test. The standard disc diffusion method was used for antimicrobial susceptibility test. Results : The resistance ratio of S. aureus against amoxicillin/clavulanic acid, ciprofloxacin, clindamycin, erythromycin, gentamicin, oxacillin, phenoxymethyl penicillin, trimethoprim/sulphamethoxazole, vancomycin, cefotaxime, and imipenem/cilastatin was 61.0, 65.3, 50.0, 76.5, 76.6, 66.9, 96.7, 15.6, 0, 87.5, and 95.5%, respectively. Resistant strains to each antibiotic were more resistant to the other antibiotics than susceptible strains. The ratio of oxacillin-resistant S. aureus (ORSA) in this area has not increased for recent five years. However, the resistance of ORSA against cefotaxime and ciprofloxacin has increased significantly. ORSA was still susceptible to trimethoprim/sulphamethoxazole (78.3%) and vancomycin (100%) Conclusion : These results offer the latest information about the antimicrobial resistance of S. aureus in Gwangju area and will be used hr reappraisal and selection of antibiotics effective against S. aureus.

신생아 파상풍의 치료에 대한 임상적 고찰 : A Clinical Review of 321 Cases

신성희 인제대학교 1980 仁濟醫學 Vol.1 No.1

1963년 1월부터 1579년 9월까지 전주 예수병원 소아과에서 입원 가료했던 신생아 파상풍 321예에 대하여 치료적인 면에서 임상적 고찰을 하였다. 최근 들어서 치료의 진전은 TAT 20,000 단위 사용, mephrobamate 및 valium의 겸용으로 인한 apnea 및 opistotonus의 호전, 급성기의 금식 및 aminofucin 등의 hyperalimentation 및 항생제의 사용과 계속적인 간호원 및 의사의 감시하에서 치료하였다. 잠복기가 7일 이상인 경후 예후가 좋았으며, 최근에 치사율은 37.36%였다. 321 cases of neonatal tetanus admitted to Presbyterian Medical Center, Jeonju, Korea, from Jan., 1963 to Sep., 1979, were evaluated. The treatment consisted of TAT, combination of sedatives and muscle relaxant, NPO during acute stage with IV hydration, prophylactic antibiotics and adequate facilities for oxygen and tracheal suction. Several changes could be pointed out on the the therapeutic aspect, for examples, kinds of sedatives, dosage of TAT, and hyperalimentation during acute stage. The following observations were made: 1.The length of the incubation period was shown significantly effect the mortality. Patients with the incubation period over 7 days had a good prognosis. 2.The alternate use of intragastric mephrotamate(100 mg q 6 h) and Valium(2 mg q 6h) was a good combination. In this combination group, there was a decreased frequency in apnea episodes and degree of the opisthotonus. 3.There was no benefit with high dose of TAT. 4.Introduction of Aminofusin during NPO period of acute stage, showed a good effect in the prevention of hypothermia. 5.The Recent mortality was 37.36%.

인구변화와 도시정책

신성희,Sin, Seong-Hui 대전발전연구원 2014 대전발전포럼 Vol.48 No.-

청소년들의 체형인식에 따른 영양소 섭취실태 및 정신건강 - 국민건강영양조사 자료를 이용하여 -

신성희,신우경,김유경 한국가정과교육학회 2017 한국가정과교육학회지 Vol.29 No.1

The objective of this study was to investigate the effects of the subjective perception to the nutrient intake and mental health of Korean adolescents by the residual method. This study was based on data from the 5th and 6th Korea National Health and Nutrition Examination Survey (2010-2014) of the 2,961 total subjects(male 1,548, female 1,413, aged 12 to 19 years). The nutrient intake was collected by using the 24 hr recall method and mental health and BMI were collected by the health interview survey and physical examination research. An analysis of the relationship between the subjective perception and BMI showed that the proportion of those with a distorted perception of their body type was the highest among adolescents with normal weight(p for trend, <.001). Especially, regarding the subjective body type, the proportion of adolescents who perceived themselves overweight was significantly higher among females as compared to that among males (p for trend, <.001). An analysis of nutrient intake status against the subjective perception showed that the group of adolescents who perceived themselves overweight had the lowest scores on the index of nutritional quality (INQ), nutritional adequacy ratio (NAR) and mean adequacy ratio (MAR) (p for trend, <.001). With respect to the daily intake of major nutrients, adolescents who perceived themselves overweight consumed the lowest amounts of total energy (p for trend, <.01) and carbohydrate (p for trend,<.001). An analysis of the mental health status of the adolescents showed that those who perceived themselves overweight had the highest levels of stress recognition and depression (p<0.01). In conclusion, the adolescentsʼ subjective perception is associated with their nutrient intake and mental health. Therefore, some educational programs are desirable to help the adolescents to have their desirable subjective perception and to increase their satisfaction with their body type. 본 연구에서는 청소년들을 대상으로 주관적인 체형 인식에 따른 영양소 섭취 문제 및 정신건강 문제를 분석하였다. 제 5기, 6기 (2010-2014년) 국민건강영양조사를 바탕으로 연구되었으며, 만 12~18세의 청소년 3,834명을 추출하여, 결측치를 제외한 총 2,961명(남자 1,548명, 여자 1,413명)을 대상으로 분석하였다. 영양조사 자료는 24시간 회상법을 통한 면접조사를 통해 수집되었으며, 정신건강과 BMI는 건강설문조사와 검진조사를 통해 자료를 수집하였다. 자료 분석 결과는 다음과 같다. 첫째, 대상자의 주관적 체형인식과 BMI와의 관련성을 살펴본 결과, 남녀 모두 정상체중인 경우 체형을 왜곡되게 인식하는 비율이 높았으며, 특히 자신을 과체중 체형이라 인식하는 대상자가 남학생보다 여학생이 유의적으로 높았다(p<.001). 둘째, 대상자의 주관적 체형인식에 따른 영양소섭취상태를 살펴본 결과, 남녀 모두 과체중인식군이 영양질적지수, 영양소 적정비에서 가장 낮은 수치를 나타냈다(p<0.01). 셋째, 대상자의 주요 영양소에 대한 1일 섭취량을 살펴본 결과, 남녀 모두 과체중인식군이 전체 에너지 섭취량, 탄수화물 섭취량에서 가장 낮은 수치를 나타냈다(p<0.01). 넷째, 대상자들의 주관적 체형인식에 따른 정신건강상태를 살펴본 결과, 대상자 모두 과체중인식군에서 스트레스 인지율과 우울감 정도가 가장 높은 수치를 보였다(p<0.01). 본 연구의 결과 청소년의 주관적 체형 인식이 영양 섭취와 정신건강에 관련이 있음을 알 수 있었다. 따라서 청소년기에 바람직한 신체 이미지상를 갖고 자신의 체형에 대한 만족감을 높이며 동시에 올바른 식생활을 할 수 있도록 가정학교사회에서의 올바른 체형 인식과 관련된 교육이 적절하게 이루어져야할 것으로 여겨진다.

인체 체액내 황색포도상구균의 증식과 철 획득 기전

신성희,이강길,이명희,양남웅,임용,김진호 대한감염학회 2000 감염 Vol.32 No.5

지적장애 고등학생의 알고리즘 학습과 사회성 기술을 위한 언플러그드 협동학습 사례 연구

신성희,한경근 한국특수교육교과교육학회 2019 특수교육교과교육연구 Vol.12 No.4

This study is a case study that observes the effect that unplugged cooperative learning in information communication application classes, which are offered as a basic curriculum selective course, have on the algorithm learning and social skills of high school students with intellectual disabilities. Six students attending special classes in High School in Gyeonggido were divided into two groups of three and units related to basic algorithm principles of basic curriculum information and communications utilization high school textbooks were taught over a course of twelve sessions with block time classes of two sessions each. Of the twelve sessions, six applied the STAD cooperative learning model and the other six applied the TGT cooperative learning model. With pre and post designs, test results from an algorithm scholastic achievement evaluation, a social skill rating scale, and a social skill behavior observation scale showed that unplugged cooperative learning improves algorithm study achievement and social skills (self-assertiveness, cooperation, self-control). This study is significant in that it made attempts in educational sites, applying unplugged methods and cooperative learning, which are information subject teaching and learning methods. 이 연구는 기본 교육과정 선택교과인 정보통신활용 수업에서 언플러그드 협동학습이 지적장애 고등학생들의 알고리즘 학습 및 사회적 기술에 미치는 영향을 살펴본 사례연구이다. 경기도 고등학교의 특수학급에 재학 중인 6명의 학생을 3명씩 두 개의 모둠으로 나누고 기본교육과정 정보통신활용 고등학교 교과서의 알고리즘 기본 원리와 관련된 단원을 총 12차시로 2차시씩 블록타임 수업으로 진행하였다. 총 12차시 중 6차시는 STAD 협동학습 모형을, 다른 6차시는 TGT 협동학습 모형을 적용하였다. 사전-사후 설계로 알고리즘 학업성취도 평가와 사회적 기술 평정 척도, 사회적 기술 행동 관찰 척도로 측정하였다. 연구 결과 알고리즘 학업성취도와 사회적 기술(자기주장, 협력, 자아통제)이 사전검사에 비해 사후검사 결과가 향상 되었다. 이 연구는 정보교과 교수 학습방법 중 언플러그드 방법과 협동학습을 적용하여 교육현장에서 시도되었다는데 의의가 있다.

Would Left Atrial Strain Provide a Role as a New Prognostigator for Atrial Fibrillation?

신성희 한국심초음파학회 2016 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.24 No.1