http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
赤血球膜의 Cholesterol含量 變動이 補體溶血에 미치는 效果
孫在卿,金麗姬,鄭泰浩 慶北大學校 醫科大學 1985 慶北醫大誌 Vol.26 No.3
세포막의 지질변동은 그세포를 표적으로 하는 세포상해 반응에 큰 영향을 줄수있다는 보고에 따라 본연구에서는 사람 정상적혈구막의 cholesterol 함량을 변동시켜 mouse antihuman hemolysin과 rabbit complement에 의한 용혈 정도를 측정하였다. 적혈구를 cholesterol로 처리한 cholesterol-enriched군의 적혈구막의 C/P molar ratio는 1.52±0.11으로 대조군의 0.82±0.08에 비해 유의성 있게 증가된 반면, 적혈구를 phosphatidylcholine으로 처리한 cholesterol-depleted군의 혈구막의 C/P molar ratio는 0.58±0.05으로 대조군에 비해 유의성 있게 감소되었다. 한편 mouse antihuman hemolysin과 가토보체를 적혈구와 반응 시켰을때 적혈구를 50% 용혈시키는 보체농도의 평균치는 cholesterol-enriched 군에서는 0.047±0.048㎖로 대조군의 0.09±0.047㎖보다 유의성있게 낮았으며, cholesterol-depleted 군에서는 0.117±0.055㎖로 대조군보다 유의성있는 높은 치를 나타내었다. 즉 적혈구막의 cholesterol함량이 높을수록 보체용혈에 대한 적혈구의 감수성이 높음을 나타내었다. The membrane lipid fluidity of normal human erythrocytes was modified by enrichment and depletion in cholesterol, and the expression of surface antigens was assayed by complement hemolysis test. Human erythrocytes, sensitized by specific mouse antihuman hemolysin, showed a significant increase in susceptibility to complement lysis after rigidification of the membrane lipid layer by incorporation of cholesterol. Conversely, fluidization of the membrane lipid layer by treatment with phosphatidylcholine for cholesterol depletion displayed increased tolerance to the complement lysis.
손재경,이시헌 대한의진균학회 2001 대한의진균학회지 Vol.6 No.2
Background: Onychomycosis is a common disease and has a tendency to increase in its incidence. Although there have been many reports about onychomycosis, very few studies about onychomycosis in the elderly have yet been conducted. Objective: The purpose of this study was to investigate the clinical and mycological features of onychomycosis in the elderly, and to evaluate the concept and attitude of the elder patients towards onychomycosis, which would affect the treatment and further infections of onychomycosis. Method: Sixty eight onychomycosis patients over 60 years old were examined clinically and surveyed by questionnaire to evaluate their concern about the onychomycosis. All the patients were confined by potassium hydroxide (KOH) examinations and underwent cultures on the both cornmeal potato agar with and without cycloheximide. An additional culture was done a week later when the intial culture showed contamination or no growth. Results: Among 648 patients with onychomycosis, 68 patients (10.5%) were over 60 years old. Fifty(73.5%) were female and 18 (26.5%) ware male. Twenty six (38.2%) had systemic illness. The average duration of onychomycosis was 13 years and the average number of onychomycosis involving nails was 4.7. Sixty three patients (92.6%) had toe nail onychomycosis. Sixty six patients (97.1%) showed distal subungal onychomycosis. Trichophyton rubrun was the main causative organism in 38 patients (55.9%). Forty one patients (60.3%) discontinued the medication in 4 weeks, and 11 (16.2) were treated over 12 weeks. From the questionnaire, only 10 patients reported previous treatment far this problem, but with duration of treatment no longer than one month. Fifty three patients had mere understanding atypical alternation in their nails before the visit. The main reasons of the discontinuing the medication were the cost of the treatment, physical discomfort due to age, and extended duration of the therapy. Conclusion: From this study, we noticed that the elder onychomycosis patients could be long time carriers of fungi because of their lack of the knowledge of onychomycosis and insufficient treatment. Therefore, it is necessary to deucate and support to treat the elder patients effectively. [Kor J Med Mycol 6(2): 77-83]
불연속적인 궤적에서 로봇 점 배치작업에 사용된 비젼 제어기법의 실용성에 대한 연구
손재경(Jae-Kyeong Son),장완식(Wan-Shik Jang) 한국생산제조학회 2011 한국생산제조학회지 Vol.20 No.4
This paper is concerned with the application of the vision control scheme for robot’s point placement task in discontinuous trajectory caused by obstacle. The proposed vision control scheme consists of four models, which are the robot’s kinematic model, vision system model, 6-parameters estimation model, and robot’s joint angles estimation model. For this study, the discontinuous trajectory by obstacle is divided into two obstacle regions. Each obstacle region consists of 3 cases, according to the variation of number of cameras that can not acquire the vision data. Then, the effects of number of cameras on the proposed robot’s vision control scheme are investigated in each obstacle region. Finally, the practicality of the proposed robot’s vision control scheme is demonstrated experimentally by performing the robot’s point placement task in discontinuous trajectory by obstacle.
손재경(Jae Gyoung Son),추봉성(Bong Sung Chu) 한국물류학회 2013 물류학회지 Vol.23 No.3
본 연구에서는 역물류(reverse logistics)의 수요특징과 흐름을 고려한 공급사슬(supply chain)의 범용적인 프레임워크를 제안하고, 각 사이트의 효율적인 운영정책을 평가ㆍ분석할 수 있는 SCM시뮬레이터(supply chain management simulator)를 개발하였다. 시뮬레이터는 고객들의 주문패턴과 차량운영계획, 운송비 등 공급사슬에 결정적인 영향을 미치는 데이터를 기반으로 각 사이트(site)의 규모와 개수, 사이트 간 연결(arc) 수요와 특성에 따른 다양한 운영정책(재고, 수송, 수거정책 등)을 평가해 볼 수 있도록 구현되었다. 예제 시나리오를 기반으로 한 시뮬레이션 수행결과에서는 재고/수송정책에 따른 시뮬레이션 총 비용 분석을 통해 보다 효율적인 공급사슬 네트워크를 비교ㆍ검증하였다. This study provided a SCM simulator that has adopted a new type of platform with demand characteristics and flows of reverse logistics. Although a large number of studies have been carried out into the development of simulation systems for the SCM, little is known about their feasibility and flexibility when applying the systems to the evaluation of operating policies with a more integrated approach between a forward logistics flow and reverse logistics flow. For this reason, we first proposed in this paper a SCM framework with respect to the question of how we consider and define the reverse logistics processes. Second, based on main data that affect those such as oder patterns from final customers, distribution plan, inventory plan, and transportation cost as well, we designed a simulator offering various opportunities for the evaluation of operating policies according to size and number of sites in a supply chain, demand of arc between the sites, and so on. From simulation results, what is shown in our investigation into transportation scenarios with different paths and parameters is that the proposed simulator is extremely useful helping strategic decision-making for supply chain management. From the view point of reasonable cost-cutting and optimal network design, various operating policies can be evaluated and investigated whether to accept or not.