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      • KCI등재

        Vitamin D maintains E-cadherin intercellular junctions by downregulating MMP-9 production in human gingival keratinocytes treated by TNF-α

        오창석,김현정,김현만 대한치주과학회 2019 Journal of Periodontal & Implant Science Vol.49 No.5

        Purpose: Despite the well-known anti-inflammatory effects of vitamin D in periodontal health, its mechanism has not been fully elucidated. In the present study, the effect of vitamin D on strengthening E-cadherin junctions (ECJs) was explored in human gingival keratinocytes (HGKs). ECJs are the major type of intercellular junction within the junctional epithelium, where loose intercellular junctions develop and microbial invasion primarily occurs. Methods: HOK-16B cells, an immortalized normal human gingival cell line, were used for the study. To mimic the inflammatory environment, cells were treated with tumor necrosis factor-alpha (TNF-α). Matrix metalloproteinases (MMPs) in the culture medium were assessed by an MMP antibody microarray and gelatin zymography. The expression of various molecules was investigated using western blotting. The extent of ECJ development was evaluated by comparing the average relative extent of the ECJs around the periphery of each cell after immunocytochemical E-cadherin staining. Vitamin D receptor (VDR) expression was examined via immunohistochemical analysis. Results: TNF-α downregulated the development of the ECJs of the HGKs. Dissociation of the ECJs by TNF-α was accompanied by the upregulation of MMP-9 production and suppressed by a specific MMP-9 inhibitor, Bay 11-7082. Exogenous MMP-9 decreased the development of ECJs. Vitamin D reduced the production of MMP-9 and attenuated the breakdown of ECJs in the HGKs treated with TNF-α. In addition, vitamin D downregulated TNF-α-induced nuclear factor kappa B (NF-κB) signaling in the HGKs. VDR was expressed in the gingival epithelium, including the junctional epithelium. Conclusions: These results suggest that vitamin D may avert TNF-α-induced downregulation of the development of ECJs in HGKs by decreasing the production of MMP-9, which was upregulated by TNF-α. Vitamin D may reinforce ECJs by downregulating NF-κB signaling, which is upregulated by TNF-α. Strengthening the epithelial barrier may be a way for vitamin D to protect the periodontium from bacterial invasion.

      • KCI등재

        외국중재판정의 승인·집행에 관한 최근 대법원 판례의 쟁점 검토 - 대법원 2017. 12. 22. 선고 2017다238837 판결을 중심으로 -

        오창석 전북대학교 부설법학연구소 2018 法學硏究 Vol.58 No.-

        Parties in the international trade typically contract to arbitrate disputes in order to avoid the courts and to maintain amicable relationship with their commercial parties. At the end of the arbitration, the arbitral tribunal will issue its decision in the form of an award. In its international enforcement, an arbitral award differs from the judgement of a court of law, since the international treaties such as New York Convention that have much greater acceptance internationally than treaties for the reciprocal enforcement of judgements. The New York Convention resulted from an international effort to make arbitration a more certain and efficient means of resolving international disputes. Since the New York Convention became available for ratification in 1958, 159 nations have ratified. Almost all the major international trading nations are parties to the New York Convention. With the continued strength of the Convention, recognition and enforcement of foreign arbitral awards are internationally guaranteed. Korea acceded to the New York Convention since 1973 with the optional “reciprocity” and “commercial” reservations. Furthermore the Korean Arbitration Act was amended in 1999, modeled after the Model Law on International Commercial Arbitration of UNCITRAL of 1985. In Korea, the New York Convention does not apply in two circumstances: first, when the award is made in a State which has not ratified the Convention; and second, when the transaction underlying the dispute is not “commercial”. Apart from the reciprocity and commercial reservations, the New York Convention itself provides grounds for denying enforcement of arbitral awards in certain circumstances. Article V establishes seven grounds on which enforcement of an award may be challenged. In this article, the author discusses the necessity of retract of the optional “reciprocity” and “commercial” reservations which are to narrow the scope of application of the New York Convention; secondly, various issues on the recognition and enforcement of an foreign arbitral awards under the Korean Arbitration Act, especially focusing on Supreme Court’s Judgement on case No. 2017DA238837 (December 22. 2017). 오늘날 국제거래계약에 있어서의 중재합의의 당사자들은 이미 그 계약의 체결시에 중재합의를 하는 경우가 대부분이고, 또 계약으로부터 분쟁에 발생한 이후에 중재합의를 하는 경우에도 분쟁을 종국적으로 해결하면서 그동안의 거래관계를 계속 유지할 수 있고, 또 상대방 당사자의 국가에서 그 집행이 용이한 중제재도에 대한 장점을 인식하고 있는 실정이다. 특히 외국중재판정도 국내중재판정과 마찬가지로 용이하게 집행할 수 있도록 하는 것이 국제상사중재제도의 관건이라고 할 수 있는데, 이러한 필요에 따라 외국중재판정의 승인과 집행에 관한 뉴욕협약이 탄생하였다. 뉴욕협약에는 현재 159개국이 가입하고 있으며, 국제거래의주요 당사국들이 거의 대부분이 이 협약에 가입함으로써 외국중재판정의 승인 및 집행도 이 협약에 따라 국제적으로 널리 보장되고 있다. 우리나라는 1973년에 상호주의 및 상사유보하에 뉴욕협약에 가입하였기 때문에, 뉴욕협약의 가입국에서 내려진 상사에 관한 중재판정은 뉴욕협약에서 제한적으로 열거하고 있는 집행거부사유가 없는 한 우리나라에서 승인 및 집행될 수 있게 되었다. 그런데 개정 중재법은 외국중재판정의 승인 및 집행에 관한 규정을 두면서, 뉴욕협약상의 상호주의 및 상사유보선언을 고려하여 뉴욕협약의 적용을 받는 외국중재판정과 그 밖의 외국중재판정을 구분하여 각각 그 집행요건 및 절차를 다르게 이원적으로 규정하고 있다. 그동안 우리나라 법원은 외국중재판정의 승인 및 집행 거부사유에 대해서도 매우 엄격하게해석함으로써 중재우호적인 입장을 보여 왔다. 최근에도 우리 대법원이 외국중재판정의 승인및 집행과 관련하여 뉴욕협약상의 승인 및 집행거부사유를 매우 엄격하게 해석하여 외국중재판정의 집행을 허가하는 판결을 한 바 있다. 이 연구에서는 대상판결에서 다루어진 외국중재판정의 승인 및 집행거부사유를 각 쟁점별로 검토하였다. 그리고 대상판결에서 쟁점으로 다루어지지는 않았지만 우리나라가 뉴욕협약상의 상호주의 및 상사유보 선언을 한 것과, 또한 이로 인하여 우리 중재법이 뉴욕협약의 적용을 받는 외국중재판정과 비적용 외국중재판정을 이원적으로 규정하고 있는 점에 대해서도 살펴보고 상호주의 및 상사유보선언의 철회필요성과 방법에 대하여 연구하였다.

      • KCI등재

        전라남도 지명업무의 개선방안 연구

        오창석 한국국토정보공사 2017 지적과 국토정보 Vol.47 No.2

        The purpose of this study is to identify the problems of the present status of the Jeollanamdo’s geographical name task by analyzing it and to suggest ways to improve it. For this purpose, the theoretical review including the definition of the geographical name as the subject of the study is conducted. Also, by analyzing the current structure of geographical name, the enactment and improvement of the ordinance of the committee on geographical name, and the management of committee on geographical name etc, the problems of the geographical name task are derived and suggestions for improvement are proposed. The results of this study are as follows: First, as a plan to improve the professionalism of the organization and the officer in charge of the geographical name task, this study suggests the unification of the department in charge of geographical name task, the specialization of the official in charge, and the development of training and teaching materials related to the geographic name task. Secondly, in order to improve the ordinance and the management of the committee on geographical name, this study suggests the enactment and improvement of the ordinance of committee on geographical name, the guidance and the supervision of the establishment and operation of the committee on geographic name, the simplification of procedures of establishing and changing geographical name, and enactment of geographic name a Law. 본 연구는 전라남도 지명업무의 현황을 분석 문제점을 파악하고 이에 대한 개선방안을 제시하기 위한 것이다. 이를 위해 연구 대상인 지명의 정의 등 이론적 고찰을 시행하고 현행 지명업무의 조직현황, 지명위원회 조례 제정 및 정비 현황, 지명위원회 운영 현황 등을 분석하여 지명업무에 대한 문제점을 도출하고 개선방안을 제시하였다. 연구 결과 첫째, 지명업무 담당조직 및 담당 공무원의 전문성 개선방안으로 지명업무 담당부서의 일원화, 담당공무원의 전문화, 지명업무 관련 교육 및 교재 개발 등을 제시하고, 둘째, 지명위원회 조례 및 운영에 대한 개선방안으로 지명위원회 조례 제정 및 정비 적극 추진, 지명위원회 구성 및 운영 지도·감독, 지명의 제정 및 변경 절차의 간소화, 지명법 제정 등을 제시 하였다.

      • KCI등재

        순환공정을 이용한 MCDI(Membrane Capacitive deionization) 탈착과정의 TDS 농축특성에 관한 연구

        오창석,오현제 대한상하수도학회 2022 상하수도학회지 Vol.36 No.6

        The CDI (Capacitive deionization) is one of the desalination technologies that use a carbon material electrode with large surface area and excellent electrical conductivity. Recently, research on a MCDI (Membrane Capacitive deionization) process, which is a combination of an ion-exchange membrane, has been actively conducted. In this study, we tried to find out the water quality of treated water and the concentration characteristics of concentrated water through TDS analysis by MCDI conventional and circulation process. In producing treated water, there was no significant difference in adsorption efficiency between MCDI conventional and circulation process. It was confirmed that both processes adsobed more than 96 %. However, the MCDI conventional process showed a low yield of 50 %, whereas the MCDI circulation process showed a high yield of 97.6 %. It's because, the wasted water was reused at desorption. In the case of the TDS concentration using MCDI circulation process, as the cycle progressed, the TDS concentration was concentrated up to 1,300 mg/L, but the rate gradually decreased. It is believed that this is because the volume of the concentrated water tank is limited, and the amount of soluble ions gradually decreases. As a result of analyzing the wasted water at MCDI circulation process through Ion Chromatography, it was confirmed that the concentration of all ions were concentrated. However, there was no significant difference in the types and proportions of analyzed ions. It is judged that the types and concentration of ions do not have a significant effect on adsorption and desorption in the MCDI circulation process.

      • KCI등재

        정수처리 공정 적용을 위한 MCDI (Membrane Capacitive Deionization) Module의 수용액 내 TDS 제거 특성에 관한 연구

        오창석,안주석,오현제,Oh, Changseog,An, Jusuk,Oh, Hyun-Je 대한상하수도학회 2021 상하수도학회지 Vol.35 No.4

        Recently, various researches have been studied, such as water treatment, water reuse, and seawater desalination using CDI (Capacitive deionization) technology. Also, applications like MCDI (Membrane capacitive deionization), FCDI (Flow-capacitive deionization), and hybrid CDI have been actively studied. This study tried to investigate various factors by an experiment on the TDS (Total dissolved solids) removal characteristics using MCDI module in aqueous solution. As a result of the TDS concentration of feed water from 500 to 2,000 mg/L, the MCDI cell broke through faster when the higher TDS concentration. In the case of TDS concentration according to the various flow rate, 100 mL/min was stable. In addition, there was no significant difference in the desorption efficiency according to the TDS concentration and method of backwash water used for desorption. As a result of using concentrated water for desorption, stable adsorption efficiency was shown. In the case of the MCDI module, the ions of the bulk solution which is escaped from the MCDI cell to the spacer during the desorption process are more important than the concentration of ions during desorption. Therefore, the MCDI process can get a larger amount of treated water than the CDI process. Also, prepare a plan that can be operated insensitive to the TDS concentration of backwash water for desorption.

      • KCI등재

        지형지세의 고저 항목 개선을 통한 개별공시지가 적정화 방안 - 전라남도 광양시를 중심으로 -

        오창석 한국지적학회 2019 한국지적학회지 Vol.35 No.2

        Focused on Jeollanam-do GwangYang city, the purpose of this study is to analyze the present condition and actual condition of land characteristics for the propertization of individual land prices, to identify the problems on the basis of them, and to suggest ways to improve them. We analyzed the actual condition of the ratification table, and obtained the objectivity of the survey results using the spatial information, and “the middle slope” add subdivided the detailed survey item and reduced the price multiplier of the standard comparison table of land prices. 본 연구는 전라남도 광양시를 중심으로 지형지세의 고저 항목 개선을 통한 개별공시지가 적정화 방안을 위한 연구로 개별공시지가에 대한 이론적 고찰을 실시하고 토지특성 고저에 대한 현황과 실태를 분석하여 이를 토대로 문제점을 파악하고 이에 지형지세의 고저항목에 대한 개선방안을 제시하기 위한 것으로, 주요 연구내용은 토지특성 지형지세 고저항목에 대한 조사 현황, 토지특성 지형지세 고저 항목별 개별공시지가 현황과, 토지가격비준표 등의 실태를 분석하였으며 연구 결과 공간정보를 활용하여 조사결과의 객관성을 확보하고, “중경사”를 추가한 토지특성 지형지세 고저 세부조사항목 세분화, 토지가격비준표의 세분화와 가격배율 축소 등을 제시하여 개별공시지가 적정화 방안을 모색 하였다.

      • KCI등재

        Learning about Dermatome Maps and Innervation of Peripheral Cutaneous Nerves Using OHP film-Overlapping

        오창석,허미선,채수진,윤성하,이승규 대한체질인류학회 2022 해부·생물인류학 (Anat Biol Anthropol) Vol.35 No.1

        Dermatome maps and the illustrations of cutaneous nerve innervation often described together in medical textbooks are difficult for some students to understand their differences and meanings. A novel pedagogical method using commercial limb models covered with white cotton pantyhose was introduced to improve the education around dermatomes and innervation of peripheral cutaneous nerves, which was previously difficult to apply in the classroom as students struggled to handle and store the large commercial models. The method of the present study was developed to solve the difficulties of the method using commercial models, and included transparent overhead projector (OHP) films and A4-sized papers imprinted with dermatome maps and cutaneous nerve maps, respectively. The maps were illustrated on upper and lower limbs with consistent shapes and sizes. These OHP films and papers were provided during class to each student, who were instructed to overlap the transparent OHP films and the papers, which improved their understanding of the differences between dermatomes and cutaneous nerve innervation and their meanings. A feedback survey with a 5-point Likert scale was conducted after the course to determine the utility of this method, and the mean values for effectiveness, satisfaction, understanding, learning engagement, and concentration all exceeded 4.0. These results indicated that the OHP film-overlapping method was useful for learning about dermatome and cutaneous nerve innervation, and it can be applied to other subjects of anatomy education.

      • KCI등재후보

        개정신탁법상 사해신탁제도에 관한 소고

        오창석 한국금융법학회 2009 金融法硏究 Vol.6 No.2

        The draft amendment to the Trust Act (the "Proposed Amendment") was released on October 27, 2009. The Proposed Amendment is aimed at overhauling the existing Trust Act which is often criticized as being outdated and inadequate for resolving many legal and practical issues currently faced in the areas of trust law. The adoption of the Proposed Amendment, which was triggered by the recent enactment of the Financial Investment Service and Capital Markets Act (which has consolidated multiple legislations (including the Trust Business Act) into one legislation), is considered a much awaited progress in the areas of trust law and a step towards finally achieving alignment with Korea's current legal, economic and financial landscape which has undergone substantial changes since the first enactment of the existing Trust Act in 1961. Among the criticisms faced by the existing Trust Act include the lack of certainty and clarity on the issues relating to what constitutes a "fraudulent trust". Such lack of certainty and clarity was viewed as one of the key factors undermining the stability and feasibility of real estate trust projects, which were actively pursued in tandem with the development of the project financing (or PF) markets in Korea (which often utilized a collateral trust arrangement) in the aftermath of the Asian financial crisis. In addition to such criticism, the existing Trust Act was viewed as failing to keep pace with the practical needs and demands of participants in transactions which resort to a collateral trust arrangement, thereby arousing many debates and controversies among legal scholars and practitioners as to how to address a widening gap between the legal framework offered by the existing Trust Act and the commercial reality. To illustrate, the existing Trust Act was regarded as particularly problematic in that it allowed for the exercise of the right of revocation of a trust in circumstances where the parties involved in such trust (namely, the trustee and the beneficiary) acted in good faith. The fact that the right of revocation of a trust could be exercised against a bona fide trustee or beneficiary for value meant that these parties could be placed in a precarious position in the absence of any fault of their own. The lack of clarity on the extent of the restoration of the original trust asset also resulted in the inability of the existing Trust Act to properly regulate or streamline the conflicting interests among the parties to a commercial trust (including the trustee and the beneficiary (especially financial institutions acting as lenders in a PF project)). Under the existing Trust Act, the status of the beneficiary was considered unclear and this aroused many questions as to whether it would be possible to exercise the right of revocation of a trust against the beneficiary. A growing consensus on the need to address many criticisms faced by, and loopholes inherent in, the existing Trust Act culminated in the drafting of the Proposed Amendment (in particular, Article 8 of the existing Trust Act, which was fraught with many legal and practical issues). Under the Proposed Amendment, some of the problems illustrated above were addressed such that (i) more flexibility is offered to the party exercising the right of revocation of a trust as such party is able to choose the counterparty it wants revoked (i.e., either the trustee or the beneficiary); (ii) certain restrictions are imposed on the exercise of the right of revocation in circumstances where the parties involved in the relevant trust are bona fide trustee or beneficiary for value; (iii) (in the case where the relevant trust is revoked for being fraudulent) certain restrictions were imposed on the extent of recovery of trust assets from the bona fide trustee without value; (iv) certain liability(ies) are imposed on the party who established a trust (the "Company")(which is subject to revocation for being fraudulent) to ensure that a...

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