신장이식 마취 5 예의 경험

정운혁,이상춘,박숙자,이병시,김성년,진수남 대한마취과학회 1970 Korean Journal of Anesthesiology Vol.3 No.1

This is a report of anesthesia for five cases of renal transplantation which was performed be tween February 1969 and August 1969 at St. Mary's Hospital, Catholic Medical College, Seoul, Korea. General of renal insufficiency of the operated cases were described. Operative technique were unilateral nephrectomy for three cases and bilateral nechprectomy with splenectomy for 2 cases ; Anesthesia was induced with epontol (propanidid) 250mgs i.v. and 4% halothane-oxygen and maintained with 1% halotbane-oxygen which was supplemented by nitrous oxide occasionally. 6% dextrose and lactated-Ringer's solution were infused. For transfusion, whole bleod was given to replace the operative blood loss. Dextran was also used to maintain adequate blood volume. Shortly before anastomosis of renal and femoral vessels, patients were haparinized. Fluids and electrolytes balance were studied pre-and post-operatively. Preoperatively, uremia and hyperpotassemia was corrected by several hemodyalysis. Urinary output after surgery showed a marked degree of diuresis up to 1800 ml/hr until second post-operative day. The special concern of anesthesia for kidney transplantation were: 1. Patients were suffering from severe uremia and metabolic disterbances. 2. Acidosis and hyperpotassemia should be corrected before surgery by hemo-or peritoneal dialysis. 3. Immunosuppressive agents made the patient less resistant to infection. 4. Anemia and hydrops was difficult to be corrected before surgery. 5. Muscle relaxants of choice were depolarizing agents, because of impaired renal excretion.

저용량의 Potassium Iodide로 치료한 스포로트리쿰증 4예

박기섭(Ghi Seob Lim),김명남(Myeung Nam Kim),이선화(Sun Wha Lee),노병인(Byung In Ro),장진효(Chin Yo Chang) 대한피부과학회 1985 대한피부과학회지 Vol.23 No.6

We experienced four cases of sporotrichosis including three lymphocutaneous type and one fixed cutaueous type. Case 1 was a 6-year old child, affected over the right chin. Case 2 was a 31-year old housewife, affected over the right forearm, Case 3 was a 53-year old housewife, affected over the right forearm and dorsum of right hand. Case 4 was a 19-year old student, affected over the left forearm. Histopathologically, chronic granulomatous inflammation with the neutrophilic ivfiltration and/or central suppuration were observed. Mycologically, typical colonies with moist, wrinkled and rnembraneous surface were cultured except in case 3. All patients were completly cured by oral administration of low dosage of potassium iodide(63. R-lllg) in a short period (50~86 days).

안톤 체호프 장막극의 무대 해석에 대한 연구(1) -홍해성, 이해랑, 이진순의 연출 작업을 중심으로

이진아 ( Chin A Lee ) 한국연극학회 2015 한국연극학 Vol.1 No.56

본 연구는 한국연극에서 안톤 체호프 장막극의 무대 해석의 역사를 고찰한다. 한국연극사에서 체호프 공연사를 살피는 일은 다음의 두 가지점에서 중요하다. 첫째는 사실주의 연극의 확립과 극복의 문제이다. 둘째는 체호프의 동시대적 해석의 문제이다. 체호프는 한국근현대연극사에서 근대연극, 리얼리즘 연극, 연출론과 연기론의 정석과 같은 것으로 여겨졌다. 이 점에서 식민지 시대의 대표적 연출가 홍해성, 한국 리얼리즘연극 시대의 대표적 연출가 이해랑, 이진순도 예외는 아니었다. 홍해성은 최초의 근대적 연출가로서 체호프 작품을 통해 조선 극계에 신극을 수립하고자 했다. 사실적인 무대를 구현하고 근대적 연기술로 역할을 형상화하는 배우들로써 근대극이란 무엇인가를 조선의 관객에게 보여주고자 했다. 그러나 조선 연극의 현실을 극복하고 그의 꿈을 이룬다는 것은 그리 녹록치 않았다. 한편, 그에게 있어서 <벚꽃동산>은 구시대 지식 계급의 몰락과 신흥 세대의 등장을 애잔한 어조로 그린 작품으로, 당대의 일반적 해석이었던 ‘분위기의 연극’ ‘애수의 연극’에서 크게 벗어나지 않았다. 다만 식민지 조선의 예술가로서의 현실이 이를 더욱낭만적이고 감상적으로 만든다. 해방 이후에도 ‘애수’ ‘시정’ ‘분위기의 연극’이라는 체호프에 대한 이해는 크게 바뀌지 않는다. 이해랑이 이해한 ‘분위기’는 어떤 의미에서는 상징적이고 이미지즘적인 것이었다. 그의 시적 정서는 모든 것을 무대위에 가시적으로 다 드러내지 않은 것, 그리하여 대사로 전달되지 않은 것을 관객이 포착하고 이해함으로써 완성되는 것이었다. 반면 이진순의 연출은 훨씬 외향적이고 과감한 것으로, 인물의 심리나 관계도 시각적으로 미장센을 통해 드러내기를 원했다. 그는 관객이 더 쉽고 분명하게 체호프의 세계에 다가갈 수 있어야 한다고 생각했고 대중적 감각으로 체호프를 무대화 했다. 홍해성으로부터 이해랑, 이진순에 이르는 체호프 해석은 어찌 보면최초로 식민지 조선에 일본을 경유하여 들어온 체호프의 무대 해석, 즉모스크바 예술극장과 스타니슬랍스키의 해석에서 크게 벗어나지 못한것이다. 물론 그들의 성취나 궁극의 해석은 스타니슬랍스키와도, 또 그들 서로 간에도 같지 않았다. 연출가들이 몸담은 시대와 연극적 요구, 그리고 개인의 미적 취향과 기질이 서로 다른 체호프를 만들어 낸 것이다. 그러나 예술극장식 체호프, 심리적 사실주의의 체호프, 시정과 분위기의 체호프 연극에 대한 관념적 지향을 세 연출가 모두 그리 쉽게 떨치지는 못한다. This study examined the history of stage interpretation of Anton Chekhov’s full-length plays in the Korean theatre stage. Studies on the impact of Chekhov on modern Korean theatre usually focused on introductions, but assessments on the achievements of individual performances and the aesthetic accomplishments have been dealt with relatively less. The performance history of Chekhov is closely related to the following three areas, which are also key issues of Korean theatre history. This is also related to the issue of the realism interpretation of Chekhov’s drama that became the canon for interpretation of Chekhov’s stages after the premiere of <Seagulls>, which was directed by K. Stanislavsky at the Moscow Arts Theatre. The second is the issue with the era-based reinterpretation of classics. In the modern historic context of Korea, it could be said to be an issue of the status of the writer named Chekhov, change of interpretation, and an era-based issue of Chekhov``s dramas. Chekhov is one of the most frequently interpreted writers in Korean theatre. The history of interpreting Chekhov can be divided into the time when modern theatre first began to become established in Joseon during the Japanese Occupation, the era when realism and psychologism theatre began being established through Chekhov after gaining independent, and the era when Russian students began to appear en masse in the Korean theatre world in the mid to late 90s after the collapse of the Soviet Union. This study deals with Chekhov stage interpretation up to the collapse of the Soviet Union. The most celebrated directors at this time were Hong Haesung, Lee Haerang, and Lee Jinsun. The interpretation of Hong Haesung’s <Cherry Orchard> is shown through the words of the director and translator Ham Daehun. They interpreted this as a piece depicting the fall of the old intellectuals and the appearance of new forces in a bittersweet tone. It shows strong influence of Stanislavsky that passed through Japan, and ‘theatre of mood’ is set as the key to the interpretation of Chekhov. Lee Haerang and Lee Jinsun are similar in that they are called the establishers of realism stage production, but their disposition are very different. While Lee Haerang pursued realism of moderation and the inner side, Lee Jinsun pursued the dramatic and the visualization of inner psychology of characters through mise-en-scene and dramatic expression. They agreed that theatre is an art of actors and because of this, they reproduced Chekhov throughout their entire career, but their organic differences made stages with different Chekhovs.

Three-month Treatment Response and Exacerbation in Chronic Obstructive Pulmonary Disease

Lee, Jung Su,Rhee, Chin Kook,Yoo, Kwang Ha,Lee, Ji-Hyun,Yoon, Ho Il,Kim, Tae-Hyung,Kim, Woo Jin,Lee, JinHwa,Lim, Seong Yong,Park, Tai Sun,Lee, Jae Seung,Lee, Sei Won,Lee, Sang-Do,Oh, Yeon-Mok The Korean Academy of Medical Sciences 2015 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.30 No.1

NMR Study on the B-Z Junction Formation of DNA Duplexes Induced by Z-DNA Binding Domain of Human ADAR1

Lee, Yeon-Mi,Kim, Hee-Eun,Park, Chin-Ju,Lee, Ae-Ree,Ahn, Hee-Chul,Cho, Sung Jae,Choi, Kwang-Ho,Choi, Byong-Seok,Lee, Joon-Hwa American Chemical Society 2012 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.134 No.11

Purification and characterization of ornithine carbamoyltransferase from the chloroplasts of Canavalia lineata leaves

Lee, Chin Bum,Kwon, Young Myung,Kim, Sang-Gu,Lee, Yi 동의대학교 기초과학연구소 1998 基礎科學硏究論文集 Vol.8 No.1

Ornithine carbamoyltransferase (OCT) was characterized from the chloroplasts of Canavalia lineata leaves. The OCT was purified 419-fold with a yield of 7.9% by streptomycin sulfate precipitation, ammonium sulfate fractionation, Sephacryl S-300 gel filtration, hydroxylapatite, and reactive red dye chromatographies. The approximate molecular weight of OCT was 107 kD by measurement from Sephacryl S-300 gel filtration. The subunit molecular weight of the enzyme was 38 kD based on SDS-PAGE. These results suggest that the native enzyme is a trimer. The OCT of C. lineata used not only ornithine but also canaline as a substrate. As for the ornithine-dependent activity, the enzyme had a pH optimum at 8.5 and Michaelis constants of 2.4 mM for L-ornithine and 0.21 mM for carbamoyl phosphate (CP). As for the canaline-dependent activity, Michaelis constants for L-canaline and CP were 11 and 0.13 mM, respectively, at pH 8.0 (optimum pH of canaline-dependent activity). S-carbamoyl-L-cysteine and L-cysteine were very strong inhibitors for the enzyme activity. Inhibition by L-cysteine was shown to be competitive with respect to ornithine, but that was shown to be noncompetitive with respect to canaline. The ornithine-dependent activity was inhibited by 90% in the presence of 2mM Cu^2+ and the canaline-dependent activity was inhibited by 91 and 100% with 2mM Cd^2+ and 2 mM Hg^2+, respectively.

Measurements of Surgeons’ Exposure to Ionizing Radiation Dose During Intraoperative Use of C-Arm Fluoroscopy

Lee, Kisung,Lee, Kyoung Min,Park, Moon Seok,Lee, Boram,Kwon, Dae Gyu,Chung, Chin Youb Lippincott Williams Wilkins, Inc. 2012 1528-1159) Vol.37 No.14

STUDY DESIGN.: Measurement of radiation dose from C-arm fluoroscopy during a simulated intraoperative use in spine surgery. OBJECTIVE.: To investigate scatter radiation doses to specific organs of surgeons during intraoperative use of C-arm fluoroscopy in spine surgery and to provide practical intraoperative guidelines. SUMMARY OF BACKGROUND DATA.: There have been studies that reported the radiation dose of C-arm fluoroscopy in various procedures. However, radiation doses to surgeons’ specific organs during spine surgery have not been sufficiently examined, and the practical intraoperative radioprotective guidelines have not been suggested. METHODS.: Scatter radiation dose (air kerma rate) was measured during the use of a C-arm on an anthropomorphic chest phantom on an operating table. Then, a whole body anthropomorphic phantom was located besides the chest phantom to simulate a surgeon, and scatter radiation doses to specific organs (eye, thyroid, breast, and gonads) and direct radiation dose to the surgeon’s hand were measured using 4 C-arm configurations (standard, inverted, translateral, and tube translateral). The effects of rotating the surgeon’s head away from the patient and of a thyroid shield were also evaluated. RESULTS.: Scatter radiation doses decreased as distance from the patient increased during C-arm fluoroscopy use. The standard and translateral C-arm configurations caused lower scatter doses to sensitive organs than inverted and tube translateral configurations. Scatter doses were highest for breast and lowest for gonads. The use of a thyroid shield and rotating the surgeon’s head away from the patient reduced scatter radiation dose to the surgeon’s thyroid and eyes. The direct radiation dose was at least 20 times greater than scatter doses to sensitive organs. CONCLUSION.: The following factors could reduce radiation exposure during intraoperative use of C-arm; (1) distance from the patient, (2) C-arm configuration, (3) radioprotective equipments, (4) rotating the surgeons’ eyes away from the patient, and (5) avoiding direct exposure of surgeons’ hands.

Molecular Analysis of Rice Plants Harboring an Ac/Ds Transposable Element-Mediated Gene Trapping Systems

Chin, Hang-Gyeong,Choe, Mi-Sook,Lee, Sung-Ho,Park, Sung-Han,Koo, Ja-Choon,Kim, No-Youl,Park, Su-Hyun,Lee, Jeung Joo,Oh, Byeong-Geun,Yi, Gi-Hwan,Kim, Soon-Chul,Choi, Hae-Choon,Cho, Moo-Je,Han, Chang-de Gyeongsang National University Chinju, Korea 1998 Plant molecular biology and biotechnology research Vol.1998 No.

RAPID RECOVERY OF PHOTOSYNTHESIS FROM PHOTOINHIBITION IS RELATED TO FATTY ACID UNSATURATION OF CHLOROPLAST MEMBRANE LIPIDS IN CHILLING-RESISTANT PLANTS

LEE, CHIN BUM,MOON, BYOUNG YONG,KANG, IN-SOON 동의대학교 기초과학연구소 1999 基礎科學硏究論文集 Vol.9 No.1

The susceptibility of chilling-resistant spinach plants, and of chilling-sensitive squash plants to photoinhibition was compared in terms of the activity of photosystem Ⅱ, in relation to the degree of fatty acid unsaturation of chloroplast membrane lipids. From thylakoid membranes of the plants, monogalactosyl diacylglycerol, digalactosyl diacylglycerol, sulfoquinovosyl diacylglycerol, and phosphatidylglycerol were seperated as major lipid classes. It was found that the content of cis-unsaturated fatty acids of phosphatidylglycerol was greater by 32% in spinach than that in squash. When leaf disks were exposed to light at 5℃, 15℃ and 25℃, photochemical efficiency of photosystem Ⅱ, measured as the ratio of the variable to the maximum fluorescence of chlorophyll, declined markedly in squash plants, as compared to spinach plants. When leaf disks were exposed to strong light in the presence of lincomycin, an inhibitor of protein synthesis in chloroplasts, photoinhibition was accelerated in the two types of plants. Moreover, lincomycin treatment abolished the differences in the degree of susceptibility to strong light, which had been observed between the two types of plants. When the extent of photoinhibition of photosystem Ⅱ-mediated electron transport was compared in thylakoid membranes isolated from the two type of plants, there were no differences in the degree of inactivation of photosystem Ⅱ activity. However, when intact leaf disks were exposed to strong light either at 10℃ or at 25℃, and then were allowed to recover either at 17℃ or at 25℃ in dim light, chilling-resistant plants such as spinach and pea showed marked recovery from photoinhibition, in contrast to chilling-sensitive plants, such as squash and sweet potato, whose recovery was strongly dependent on the temperature. These findings are discussed in relation to the unsaturation of fatty acids in membrane phosphatidylglycerol. It appears that fatty acid unsaturation of membrane lipids accelerates the recovery of photosystem Ⅱ from photoinhibition, without affecting the photo-induced inactivation process of photosystem Ⅱ associated with photoinhibition.

Differences in the rate of dephosphorylation of thylakoid proteins during dark incubation after chilling in the light between two rice (Oriza sativa L.) varieties

Lee, Choon-Hwan,Kwon, Young Myung,Lee, Chin Bum,Park, Hyun-Sook,Hwang, Hong Jin,Kim, Jin-Hong 동의대학교 기초과학연구소 1998 基礎科學硏究論文集 Vol.8 No.1

To reveal the adaptation or defense mechanism against chilling stress, we investigated the differences in the changes in chlorophyll fluorescence parameters during chilling in the light and subsequent recovery between two rice varieties, a cold-tolerant Dongjin-byeo and a chilling-sensitive IR841. Photochemical efficiency (F_v/F_m) was reduced during light-chilling and increased during recovery. Significant differences between two varieties were observed during dark recovery, rather than during light-chilling for 6 h. The reduced F_v/F_m caused by 6 h light-chilling was recovered almost completely after 23 h dark incubation at 25℃. The dark recovery process consisted of two phases; a rapid phase reached its plateau within 10-20 min, and a slow phase proceeded slowly until 23 h. Dongjin-byeo recovered faster than IR841, and F_v/F_m of Dongjin-byeo reached 90% of the value in 23 h during the 10 min rapid phase. F_v/F_m of IR841 reached only 77% of the value reached after 23 h during the rapid phase, and increased slowly during the following slow phase. The dark recovery process was not inhibited by lincomycin (a chloroplast encoded protein synthesis inhibitor), but inhibited by phosphatase inhibitors (NaF, iodosobenzoate and iodoacetate). The recovery process was partially inhibited by light, and the light recovery process was inhibited by lincomycin. In thylakoids isolated from 6 h chilled leaf segments of the two varieties, no significant decrease in photosynthetic electron transport activity was observed. These results suggest that photosynthetic apparatus is not damaged, but down-regulated by phosphorylation of thylakoid proteins during 6 h light-chilling, and the rate of dephosphorylation or the activity of kinase/phosphatase enzyme system is higher in Dongjin-byeo than that in IR841. The possible involvement of thylakoid phosphoproteins in the recovery process is discussed.