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      • 홧병 경험군과 홧병 비경험군간의 홧병의 질병개념에 대한 비교연구

        홍진표,김창윤,이창화,김성윤,박인호,이철,한오수 울산대학교 의과대학 1995 울산의대학술지 Vol.4 No.2

        Objective The concept of Hwa-byung in terms of illness entity remains vague. In order to clarify such illness entity, this study was conducted to find out differences and similarities in subjects who experienced Hwa-byung and those who did not experienced Hwa-byung from a wide distribution within the general population. Method (1) Test Material The questionnaires were made up with reference to previously published articles on Hwa-byung, to SCL-90-R and to diagnostic criteria of DSM-Ⅲ-R. The questionnaires included the subject's demographic variables, their awareness of Hwa-byung, their experience of Hwa-byung, and also their opinions about its possible causes, precipitating factors, symptomatology, effective treatment modalities, course and prognosis of Hwa-byung. Such questionnaires were given to 50 subjects, all of whom are psychiatric out-patients at Asan Medical Center, for determining its validity and reliability before selecting 27 questionnaires. (2) Subject Subjects were recruited from among patients and their family members who visited the out-patient clinics of seven different departments at Asan Medical Center in Seoul a large metropolis (N=334), the out-patient clinics of seven different departments of Hae Sung General Hospital in the industrial city of Ulsan, Korea (N=299) and the seven branches of the public health center of Yeonchun county, Korea (N=262), a rural area. From these 895 subjects, 67 subjects who don't know about Hwa-byung and 34 subjects who didn't answered to the question on experience were eliminated from study subjects. The final number of study subjects was 794. (3) Methods of analysis The subjects were divided into the Hwa-byung experienced group and the Hwa-byung inexperienced group. The demographic data and the concepts of Hwa-byung were statistically analyzed by the student t-test or the chi-sq test. Results and Discussion The mean age of the Hwa-byung experienced group is significantly higher than that of the Hwa-byung inexperienced group. MOre women experienced Hwa-byung than men and lesser educated subjects experienced significantly more Hwa-byung. The place of residence, the place of upbringing and socioeconomic status have no significant difference statistically between the two groups. Both groups considered the primary cause of Hwa-byung as being psychological origin. However in the Hwa-byung experienced group, more subjects considered that the supernatural factor was the primary cause of Hwa-byung. One of the primary precipitating events causing Hwa-byung in both groups is conflict in interpersonal relationships ; however, the Hwa-byung inexperienced group exhibited more experiences in the realm of economical losses such as "failure of business" or "loss of capital" as precipitating factors causing Hwa-byung. Both groups consider that the symptoms of Hwa-byung are a combination of multiple physical and mental symptoms. With particular respect to in mental symptoms, such as depressive symptoms, anxiety symptoms and hostility are thought to be prominent features. As effective treatment modalities, subjects in both groups consider that both himself and his family members should make effort to resolve intrafamilial conflicts. But in contrast with the Hwa-byung inexperienced group, the Hwa-byung experienced group requires more concrete and more attention-giving modalities as important treatment strategies. The Hwa-byung experienced group considers its prognosis more grave than the Hwa-byung inexperienced group.

      • Bupivacaine과 ropivacaine이 Xenopus oocyte에 발현된 HERG 전류에 미치는 영향

        김국성,이규승,김효신,손숙진,이상도,김광진,전병화,김윤희,박진봉 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

        Bupivacaine is an amide-type local anesthetic widely used for regional anesthesia. Ropivacaine is developed as a less cardiotoxic alternatives to bupivacaine. In the present study, we have analyzed the effects of bupivacaine and ropivacaine on HERG currents expressed in Xenopus oocytes. Bupivacaine and ropivacaine(3∼1,000μM) blocked HERG currents in a concentration dependent manner. EC_(50) was 26.1±3.1μM(n_(R) 0.65±0.04) and 43.5±7.9μM(n_(H) 0.99±0.13) in bupivacaine and ropivacaine, respectively. Bupivacaine and ropivacaine did not affect the activation and deactivation kinetics of HERG channels. However, the drugs decreased the slope conductance measured from fully activated current-voltage relationship curves. These results suggest that bupivacaine and ropivacaine have a similarinhibitory effect on HERG channels, which could be a possible cellular mechanism of LQT or ventricular arrythmia by the drugs.

      • KCI등재

        Three-Dimensional Z-Plasty(Yoon's Method)를 이용한 내안각 췌피 성형술

        박흥식,김우신,윤진호,나민화,김한중 대한미용성형외과학회 1997 Archives of Aesthetic Plastic Surgery Vol.3 No.1

        The presence of epicanthal folds in Asian eyelids is one of their unique features, in combination with the lack of supratarsal folds. Western culture has influenced many people to prefer to eliminate the prominent epicanthal fold. A number of surgical techniques have been suggested for their correction. However, difficulty with design, excessive and prominent scarring of medial canthal and nasal area, recurrence, and rigidity of application are potential problems associated with many procedures. This paper describes a epicanthoplasty with three-dimensional Z-plasty. Through epicanthal fold incision, the medial canthal tendon is medially advanced and sutured to the periosteum of nasal bone. After the transposition of the flaps, trimming of the flap is usually required. Three-dimensional Z-plasty creates the attractive eyes. From March, 1995 to March, 1997, the technique was applied to 37 patients with epicanthal fold and was performed with or without double-fold operation. There were 34 females and 3 males with ages ranging from 17 to 30 years. Through 2 years follow-up, this technique has delivered esthetically good results with minimal postoperative scar and could made the reduction of ICD from 40 ± 2.13 mm to 34 ± 1.98 mm. The advantages of epicanthoplasty procedure using three-dimensional Z-plasty(Yoon's method) are as follows; 1) simple in design 2)minimal postoperative scar in the medial canthal area 3) versatile in its application 4) no recurrence 5) no hypertrophic scar 6) preserving ethnic identity.

      • SCOPUSKCI등재
      • KCI등재

        토끼 복부 내벽으로부터 분리된 경락으로 믿어지는 관조직

        손준형 ( Joon Hyung Sohn ),윤진하 ( Jin-ha Yoon ),김영주 ( Young Joo Kim ),김민경 ( Min Kyung Kim ),김지화 ( Ji Hwa Kim ),권오현 ( Ohyun Kwon ),김현원 ( Hyun-won Kim ) 대한미용학회 2016 대한미용학회지 Vol.12 No.4

        Investigation of meridian line and acupoints as anatomical entities should be very important, as acupuncture and meridian massage for medical purpose in the hospital or for skin care in beauty shop are each based on the traditional meridian theory. We isolated tubular structures under the skin of rabbits where the traditional meridian lines are located. The characteristics of these tubular structures isolated from the abdominal wall matches those of Bonghan tubes and Bonghan tubules found by Bong Han Kim. The Bonghan theory established by Bong Han Kim suggests that meridian lines consist of Bonghan tubes and Bonghan tubules. We could observe the presence of large cells inside the Bonghan tubule and the presence of small granules referred to as Sanal in Bonghan theory inside the striae consisting of the Bonghan tubules. Present research suggests that there exist a third unique tubular structure where Sanals flow other than Bonghan tube and Bonghan tubules.

      • 國內飼育 젖소의 疾病에 관한 調査硏究

        尹和重,李元暢,金昌漢 건국대학교 1979 學術誌 Vol.23 No.2

        The studies on the morbidity rate of the dairy cows in Korea from October 31, 1977 to November 30, 1978 were intended. The results obtained were as follows : 1.During the period of one year, 11,060 cases of the disease were shown by the clinical examination. Among them, the surgical disease was 7.70%(morbidity rate : 31.8 per 1.000), the disease of internal medicine was 36.31%(146.4 per 1.000) and obstetrical disease was 55.78%(225.0 per 1.000). 2.Foot rot of 21.88% among 873 cases of 30 kinds in the surgical disease showed the highest rate of morbidity Indigestion(dyspepsia) of 13.99% among 4,016 cases of 22 kinds in the disease of internal medicine was the highest rate of morbidity Endometritis of 25.85% among 6,171 cases of 28 kinds in the disease of obstertics was the highest rate of morbidity. 3.Ten kinds of main disease in dairy cows were endometritis (L4.42%), retained placenta(11.33%), mastitis(9.47%), indigestion (5.8%), milk fever (4.45%), ovarian cyst (4.39%), diarrhea (4.35%), pneumonia (3.36%), ovarian hypofunction (2.97%) and enteritis (2.7%), respectively. 4.The strains of causative organism in 320 cases of clinical mastitis were staphyococcus spp, (25%), streptococcus spp. (40%), other bacteria spp. (9%) and fungi spp.(16%). 5.Fifty-one strains of bactria were isolates from the cases of clinical mastitis : Two strains (3.9%) were Phycomycetes spp., twenty-four strains (47.1%) were Ascomycetes spp. and twenty-five strains (49.0%) were Fungi Imperfecti. 6.The sensitivity rate(%) of the bacteria isolated from the cow milk of the clinical mastitis to 9 kinds of antibacterial drug was 14.1% to penicillin-G, 17.8% to streptomycin, 14.9% to erythromycin,20.0% to chloramphenicol, 55.0% to kanamycin, 66.9% to neomycin, 13.8% to tetracyclin, 10.8% to novobiocin and 66.2% to sulfaisodindin.

      • CSVT법에 의해 증착시킨 CdS 박막의 전기적 특성

        김화민,최제헌,이병로,김태만,윤대현 대구효성가톨릭대학교 자연과학연구소 1991 基礎科學硏究論集 Vol.1991 No.1

        CSVT법에 의해 증착시킨 CdS 박막의 전기적 특성 및 열전기 특성을 조사하기 위하여 시료의 X-선 회절, 직류 전기전도도, Hall 이동도 그리고 TSC를 측정하였다. 그 결과 CSVT 법에 의해 제작된 CdS 박막이 보통중착법에 의한 것에 비하여 결정성장이 향상되고 Hall 이동도가 크며 저항이 작다는 것을 알았다. 또한 TSC 측정결과, 광조사 조건에 따라 TSC 피크가 다르게 나타나며 이러한 피크 특성은 photochemical reaction model로서 설명될 수 있고, 그리고 제작조건이 다른 두 CdS 박막에서 나타나는 TSC 피크의 비교로부터 CSVT법에 의해 제작된 시료가 보통증착법에 의한 것보다 상온 이상에서의 photochemical reaction 효과 적음을 알 수 있다. To investigate electrical property and thermally stimulated current (TSC) for the CdS films which were grown by close-spaced vapor transport (CSVT), the measurements of X-ray diffraction pattern (XRD), d.c. conductivity, Hall mobility and TSC were carried out. Form the result of the measurements, CSVT-CdS films are found to be better oriented and to be less resistive with better mobility as compared with the films evaporated by the conventional method. TSC spectra under illumination conditions show different TSC peaks. These can be explained by photochemical reaction model. The result suggests that the effect of photochemical reaction above room temperature is to be less than conventional evaporated films in the case of CSVT-CdS films.

      • KCI등재

        양호교사 자격연수교과과정 개발에 관한 연구

        김화중,김영임,윤순녕 韓國學校保健學會 1996 韓國學校保健學會誌 Vol.9 No.1

        School health promotion is related to reinforce on various roles of school health teachers including health instruction, health services, healthful school living. In this aspects, there would be necessory for qualified continuous education proceed to activate roles of school health teachers. So the objectives of this study are first, to develop curriculum framework for inservice training of health school nurses, second, to descrive of curriculum objectives, third, to state of curriculum objectives and learning methods. There were used study methods as literature review, expert conferencing and workshop. Major results are as follows; 1. Curriculum framwork for inservice training of health school nurses was constitute of major variables of health care model and direct services role of school health teacher such as health service, health instruction and healthful environment area. 2. The curriculum for health instruction were different from elementary school and middle school. 3. Time distribution for curriculum was composed of that health service is 12hours, health instruction is 96 hours and healthful environmenet is 12 hours. 4. The learning methods for inservice training were suggested to intensify positive attitude through the discussion and practical exercise. 5. The curriculum objectives were classified by total, area and a course of study and time summary table was suggested. In conclusion, the developed curriculum would be contribute to improve of practical ability for school health teachers. And to increase of inservice training effect, there should be operate in order to participate trainees activately and to be educate concurrently. Also, there are necessary for execute in series of the program such as standized text developing by course, evaluation index developing and instructor education etc.

      • 백서의 적출된 기도평활근에서 Ketamine의 이완효과

        윤석화,김윤희,김상수,이상묵 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

        The effects of anesthetics on airway smooth muscle tone are important in the management of patients with asthma. Airway epithelial cells and vascular endothelial cells modulate the tone of the underlying smooth muscle by releasing relaxing factors such as prostanoids and nitric oxide (NO). Ketamine, at concentrations achieved with the usual clinical doses, has a direct relaxant effect on airway smooth muscle. In the present study we evaluated whether the relaxant effect of ketamine depend on any of the epithelium-derived relaxing factors. Isolated rat tracheal preparations mounted in water-jacketed organ baths filled with modified Tris Tyrode buffer solution with 100% oxygen at 37˚C for recording isometric contractile force. In the first experimental step, Tracheae, in the absence and in the presence of epithelium, were contracted with acetylcholine(10^-8M-10^-3M), and we plotted concentration -response curve for the Ach. And then we examined the inhibitory effect of ketamine(10^-5 and 10^-4M) on the concentration-response curve for Ach. In the second experimental steps, we studied the effect of N-omega-nitro L-arginine methylester(L-NAME) on the relaxant activity of ketamine(10^-6-10^-3M) on trachea contracted by 10^-5M Ach. In the result, 1) Removal of the tracheal epithelium did not change the response to Ach. 2) 10^-5M ketamine not significantly changed, but 10^-4 M ketamine shifted to the right the concentration-response curves for Ach in both intact and denuded epithelium rings. 3) L-NAME did not influence the relaxant effect of ketamine on trachea contracted by 10^-5 M Ach. These results indicate that ketamine-induced tracheal smooth muscle relaxation is epithelium-independent and may be is mediated by inhibition of Ca^++ influx in nonspecific way.

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