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Sunmin Park,Won Park,Shin-Hyung Park,Joo Young Kim,Jin Hee Kim,Haeyoung Kim,Yeon-Sil Kim,Won Kyung Cho,Won Sup Yoon,Dae Sik Yang 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.3
Objective: This study aimed to evaluate the oncologic outcomes according to disease burden in uterine cervical cancer patients with metachronous distant metastases. Methods: Between 2005 and 2015, 163 patients with metachronous distant metastases from uterine cervical cancer after receiving a definitive therapy were evaluated at seven institutions in Korea. Low metastatic burden was defined as less than 5 metastatic sites, whereas high metastatic burden was others. Each metastasis site was divided based on the lymph node (LN) and organs affected. The overall survival (OS) and progression-free survival (PFS) were assessed. Cox proportional hazards models, including other clinical variables, were used to evaluate the survival outcomes. Results: The median follow-up duration was 22.2 months (range: 0.3–174.8 months). Para- aortic LNs (56.4%), lungs (26.4%), supraclavicular LNs (18.4%), and peritoneum (13.5%) were found to be the common metastasis sites. Among 37 patients with a single metastasis, 17 (45.9%) had LN metastases and 20 (54.1%) had organ metastases. The 1- and 2-year OS rates were 73.9% and 55.0%, respectively, whereas the PFS rates were 67.2% and 42.9%, respectively. SCC Ag after recurrence and high metastatic burden were significant factors affecting the OS (p=0.004 and p<0.001, respectively). Distant organ recurrence, short disease-free interval (≤2 years), and high metastatic burden were unfavorable factors for PFS (p=0.003, p=0.011, and p=0.002, respectively). Conclusion: A favorable oncologic outcome can be expected by performing salvage treatments in selected patients with a long disease-free interval, low metastatic burden, and/ or lymphatic-only metastasis.
( Sunmin Yim ),( Jung Yup Kim ),( Jae Yun Lim ),( Ju-yeon Choi ),( Han-saem Kim ),( Jung-in Kim ),( Jung Min ),( Joon Hong Min ),( Young Jun Choi ),( Jae Hui Nam ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2
Background: A low-fluence 1064-nm Q-switched neodymium-doped yttrium aluminum garnet (QSND) laser has been used for treatment of pigmented disorders. However, the photobiological mechanism of the low-fluence 1064-nm QSND laser is not yet fully understood. Objectives: To evaluate inhibitory effects of the low-fluence 1064-nm QSND laser on the melanogenesis and assess whether increasing the number of passes of low-fluence the 1064-nm QSND laser has positive correlation with improvements of the pigmentation. Methods: The skins of six Hair Moprpholoy-2 melanin-possessing hairless mice were treated with ultraviolet B radiation followed by 0, 2, 4, 6 passes the low-fluence 1064-nm QSND laser. Pigmentation changes of skins were evaluated with spectrophotometry and pigmentation-related protein expressions. Additionally, biopsy specimens were obtained to figure out the difference of melanin particles. Results: The low-fluence 1064-nm QSND laser improved the lightness of the skin in comparison to the control skin. Biopsy specimens showed decreased amounts of melanin particles. In the western blot of the specimen, expressions of MITF and tyrosinase were reduced. Conclusion: The low-fluence 1064-nm QSND laser has effects on the melanogenesis which change expressions of the pigmentation-related proteins. Moreover, the more passes of the laser toning can bring the more progress on the skin pigmentation.
( Jung Yup Kim ),( Sunmin Yim ),( Jae Yun Lim ),( Ju-yeon Choi ),( Han-saem Kim ),( Jung-in Kim ),( Jung Min ),( Joon Hong Min ),( Young Jun Choi ),( Jae Hui Nam ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2
Background: Scars can affect patients, leading to emotional complications. Various laser technologies including fractional laser, Q-Switched Nd:YAG laser, and pulsed dye laser have been tried to revise the scar. Up to now, there has been no reliable study to evaluate an effect of picosecond Nd:YAG laser for reducing scars. Objectives: This retrospective clinical study was performed to investigate the beneficial effect of picosecond Nd:YAG laser in treatment for hypertrophic scars. Methods: A retrospective review was conducted on patients treated with picosecond Nd:YAG laser for the purpose of scar improvement. Twenty-seven patients with hypertrophic scars were included in this study. The vancouver scar scale (VSS), global assessment score (GAS), and participant’s subjective satisfaction were used to determine the effect of scar improvement. All side effects were recorded to assess the safety of the modality. Results: Mean age of patients was 33.4±15.2 years old and male-to-female ratio was 2:3. Mean total treatment session was 3.4±1.3 and mean total duration of treatment was 13±7.3 weeks. Average VSS score was remarkably decreased after treatment. Average GAS and participant’s satisfaction indicated fair cosmetic improvement. No significant side effects were observed during follow-up. Conclusion: Picosecond Nd:YAG laser may be considered as an effective and safe optional modality for the treatment of scar.
김화영(Hwayoung Kim),김형민(Hyungmin Kim),송민수(Minsu Song),안지훈(Jihun An),김강현(Ganghyun Kim),김선민(Sunmin Kim),김찬현(Chanhyun Kim),박성우(Seoungwoo Park),이준우(Junu Lee),이준기(Joonki Rhee),임재혁(Jaehyuk Im),정승수(Seungsu Jeo 한국추진공학회 2022 한국추진공학회 학술대회논문집 Vol.2022 No.5
본 논문은 경기대학교 KURBC 팀이 설계한 모듈형 신기전K22에 대한 설계과정과 그 근거를 서술하였다. 로켓의 임무는 ‘로켓 발사 후 낙하 시 낙하산 사출 및 안전한 회수’이다. 목표 고도는 400m, 연료는 질산칼륨-소르비톨(KNSB)이다. 낙하산 사출 방법은 동체와 낙하산이 안전하게 보호되는 용수철 사출을 선택했다. 본 팀은 이번 대회에서 CFRP 카본으로 로켓의 동체를 만들고, 내부를 모듈로 구성함으로써 차별점을 두었다. 또한 RF 장거리 통신 기술을 이용하여 발사 전후의 데이터를 체계적으로 기록하여 후속 연구에 참고할 예정이다. This paper describes the design process and basis for the modular Shinkijeon-K22 designed by the KURBC team of Kyonggi University. The rockets mission is devising a method for parachute injection and safe recovery when falling after launching the rocket. The target altitude is 400 m and the fuel is potassium nitrate-solvitol (KNSB). The spring injection method was used for the parachute injection, in which the fuselage and parachute are safely protected. We made a difference by making the rockets fuselage with CFRP carbon and configuring the interior as a module. In addition, RF long-distance communication technology will be used to systematically record data before and after launch and refer it to subsequent studies.
A case of inverted type a (clonal) nevus
( Sunmin Yim ),( Hyeon Jeong Park ),( Junghwa Yang ),( Yunho Lee ),( Jung Yup Kim ),( Jae Yun Lim ),( Young Jun Choi ),( Jae-hui Nam ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1
Inverted type A (clonal) nevus is a unusual type of melanocytic nevus. It contains pigmented nests of type A nevus cells in the depth of a banal. The nest is occasionally surrounded by type B or C nevus cells. Therefore, type A nevus cells are layered in deeper portion of nevus and Type B and C nevus cells are observed on superficial layers. An unusual presentation of inverted type A nevus have been rarely reported with superficial neurotization. We described a case of a 68 year-old female complained of solitary, 0.4 cm-sized, dome shaped, brownish to skin-colored papule on the occiput. There was no pruritus or pain on the lesion. The excision biopsy was performed. The histology examination revealed clustered, swirling, epithelioid, type A nevus cells proliferation in the deep portion of perifollicular area. The dense, basophilic type B nevus cells were surrounding the nests of type A cells. Moreover, extensive neurotized type C nevus cells appeared in the upper dermis. No atypia and abnormal mitosis were observed. It could be diagnosed with inverted type A nevus based on the clinical and histological findings.
( Sunmin Yim ),( Hyeon Jeong Park ),( Junghwa Yang ),( Yun Ho Lee ),( Jung Yup Kim ),( Jae Yun Lim ),( Heun Joo Lee ),( Young Jun Choi ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2
Background: Chronic pruritus without cutaneous manifestation is one of the most common chief complaints in Dermatology. It persists more than 6 weeks and impacts a great amount of patients’ quality of life. Correlation between IgE related immune reaction and presentation of chronic pruritus has been studied. Objectives: To analyze clinical characteristics of chronic pruritus patients without cutaneous manifestation. Methods: This was a retrospective study that enrolled 128 patients suffering from chronic pruritus without cutaneous manifestation. We reviewed electric medical records of these patients who visited Kangbuk Samsung Hospital in 2017. Results: 128 patients of chronic pruritus without cutaneous manifestation were investigated (70 males and 58 females, average age 41.0). Their initial laboratory test revealed following figures; average serum IgE level, 639 IU/ml; average number of Multiple allergosorbent test (MAST) positive allergens, 2.64. The number of patients presenting more than 100 IU/ml IgE level was 91 (71%). The mean history of illness and follow up period were 761 days and 144 days, respectively. Average 2 antihistamine agents have been used for symptoms. 30 patients (23%) have been prescribed additional methylprednisolone or cyclosporine for persisting pruritus. Conclusion: This study demonstrated that chronic pruritus patients without cutaneous manifestation have similar clinical characteristics in allergic skin diseases, including chronic urticaria, atopic dermatitis.
[P014] Clinical efficacy of laser epilation as an early treatment modality of Becker`s nevus
( Sunmin Yim ),( Junghwa Yang ),( Yun Ho Lee ),( Jung Yup Kim ),( Jae Yun Lim ),( Ju-yeon Choi ),( Han-saem Kim ),( Joon Hong Min ),( Young Jun Choi ),( Jae-hui Nam ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1
Background: Becker`s nevus is a relatively common harmatoma that, in adult patients, is usually accompanied with hair growth. Objectives: The purpose of this study is to evaluate the efficacy of epilation laser treatments, namely, long-pulsed 1064-nm Nd:YAG and 755-nm Alexandrite laser, in the treatment of Becker`s nevus Methods: Retrospective chart reviews and photographic analyses were performed for patients treated with epilation lasers. Clinical improvement was assessed by two blinded physicians using 5-point global assessment scale. Results: Total 13 patients (8 males, 5 females) with Fitzpatrick skin types IV, a mean age 2 of 5.0±9.4 years, were included. The most common lesions were on the cheeks (4 patients, 30.8 %) and every lesion showed scattered patterns of hair growth. 8 patients were treated with long-pulsed 1064-nm Nd:YAG laser; 4 patients were treated with 755-nm Alexandrite laser and one patient was treated with both lasers. The mean treatment interval was 28.7±6.0 days. The median total treatment session was 2.0 (interquartile range 1.0). After laser epilation therapy, 11 patients (84.6 %) showed an improvement margin of 50 %. The difference of treatment response between two lasers was not clinically significant. (p=0.80) No persistent and serious adverse events were observed during the follow-up period. Conclusion: Laser epilation can be an effective, early therapeutic option for the treatment of Becker`s nevus.