상한논에 대한 정신의학적 연구

문상태(Sang Tae Moon),신용현(Yong Hyun Shin),구병수(Byung Su Gu) 대한한방신경정신과학회 2000 동의신경정신과학회지 Vol.11 No.1

This study was aimed to get the course which is caused by Neuropsychiatric symptoms in Sang-Han. Therefore this study is based on 『Euhak-Ipmun. Sang-Han』(『醫學入門.傷寒』) classfied mainly by symptoms. The results were summerized as follows: 1. Neuropsychiatric symptoms in 『Euhak-Ipmun. Sang-Han』(『醫學入門. 傷寒』) are explained as Pal-Gang(八綱), which shows those are settled down to a systematic oriental medical theory. 2. Pal-Bup (八法) used in the cure of symptomatische psychose in 『Euhak-Ipmun. Sang-Han』(『醫學入門. 傷寒』), which is intended to boost the effect of cure, choosing the respondent cure method about various causes. 3. Pal-Gang(八綱) and Pal-Bup(八法) in『Euhak-Ipmun. Sang-Han』(『醫學入門·傷寒』) are improved by Lee-Chun(李 ) who added Jang-gi(張機)`s Sang Han theory and new medical thought in the ages of Geum. Won. 4. Lee-Chun(李 ) believed that Neuropsychiatric symptoms which appeared in Sang Hang is caused by the Unbalance(不平). So he wanted to reach harmony of Jeong(精), QI(氣), Shin(神), Hyul(血) after improving the status of Unbalance(『不平』) toward the status of Balance(平).

Photonic Crystals: Integration of Colloidal Photonic Crystals toward Miniaturized Spectrometers (Adv. Mater. 9/2010)

Kim, Shin-Hyun,Park, Hyo Sung,Choi, Jae Hoon,Shim, Jae Won,Yang, Seung-Man WILEY-VCH Verlag 2010 Advanced materials Vol.22 No.9

<B>Graphic Abstract</B> <P>The cover shows a schematic illustration of patterned colloidal photonic crystals with different bandgap positions. When an unknown light source impinges on the patterned photonic crystals, the light information can be identified from the reflection intensity profile of the constituent photonic crystals. The two optical microscopy images and background image display integrated photonic crystals with 20 different bandgaps spanning the entire visible range, and the SEM image shows the cross-section of the photonic crystal stripes, as reported by Shin-Hyun Kim, Seung-Man Yang, and co-workers on p. 946. <img src='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content.gif' alt='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content'> </P>

한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

녹동균 세포외막 단백질 백신 CFC-1-101의 안정성 및 면역원성 검토 : 임상 제 Ⅰ/Ⅱa상 시험

장인진,김익상,유경상,임동석,김형기,신상구,장우현,박완제,이나경,정상보,안동호,조양제,안보영,이윤하,김영지,남성우,김현수 대한감염학회 1998 감염 Vol.30 No.3

목적 : 제일제당에서는 녹농균의 세포외막 단밸질을 유효성분으로 하는 백신인 CFC-101을 개발하였으며, 동물시험에서 이 백신의 안전성과 유효성을 입증하였다. 본 연구에서는 이 녹농균 백신의 인체에 대한 안전성과 면역원성을 평가하는 동시에 인체 접종시의 최적 투여 용량을 결정하기 위하여 제 I/Ⅱa상 임상시험을 수행하였다. 방법 : 건강한 성인 남자를 피험자로 선별하여 각 용량군에 백신투여자 6명, 위약투여자 2명을 배정하였다. 백신 투여군은 0.25mg, 0.5mg 또는 1.0mg 용량의 녹농균 백신을 7일 간격으로 3회에 걸쳐 근육주사 하였으며, 위약 투여군에게는 세포외막 단백질을 제외한 동일한 성분을 투여하였다. 백신접종 후 국소적 또는 전신적인 반응의 발생여부를 관찰하고, 혈액시료를 체취하여 백신의 역가와 유효성을 검정하였다. 결과 : 녹농균 백신 CFC-101은 모든 접종자에서 양호한 내약성을 보였다. 또한 0.5mg 과 1.0mg 백신 투여군에서는 100%의 항체양전율을 나타내었다. 생성된 항체는 녹농균 세포외막단백질에 특이성을 보였고, 녹농균 감염에 대해 방어효능이 있었다. 결론 : 이와같은 결과로부터 이 녹농균 백신은 인체에 안전하게 투여할 수 있으며, 높은 항체 생성능으로 감염방어 효능을 보이고 0.5mg과 1.0mg이 최적용량인 것으로 판단되었다. Background : We developed a Pseudomonas aeruginosa outer membrane protein(OMP) vaccine CFC-101, and the prophylactic efficacy of which has been demonstrated in animal models. In order to evaluate the safety and immunogenicity of the P. aeruginosa vaccine, we carried out a phase I/Ⅱa clinical trial in healthy male volunteers. Methods : Groups of eight volunteers, including two placebo subjects, were vaccinated intramuscularly with three doses of 0.25, 0.5 or 1.0 mg of the vaccine at one week intervals. Sings of systemic and local reactions observed after vaccination were recorded for each vaccinee for 5 days. Physical examinations were performed on days 0, 1, 7, 8, 14, 15, 21, and 42, and clinical laboratory tests were done on days 0, 3, and 21. Blood samples for assay of serum antibody levels were obtained up to 42 days after the first vaccination. Results : The vaccine was generally well tolerated by all vaccinees, showing no significant side effects. In the three dosage groups, all vaccinees, except one receiving the 0.25 mg dose, showed significant elevation in serum IgG antibody titers against the vaccine proteins, indicating 100% seroconversion in 0.5 and 1.0 mg groups. The human antibodies induced by the vaccine were specific for P. aeruginosa OMPs, as confirmed by western blot analysis and immunoprecipitation assays. The capacity of the human antisera to enhance opsonophagocytic killing activity by polymorphonuclear leukocytes and to confer protection against P. aeruginosa infections indicates that the antibodies elicited by the vaccine have protective efficacy. Conclusion : We conclude that the P. aeruginosa OMP vaccine is safe and effective for human use and its optimal dose to be 0.5 or 1.0 mg.

치아 맹출전 시행한 기관 삽관이 유치열기에 미치는 영향에 대한 증례보고

신윤경,Hyun, Hong-Keun,김영재,김정욱,장기택,이상훈,김종철,한세현 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.3

유치 맹출전에 치조융기에 가해진 외상은 유치의 맹출 지연 및 형태이상,치배의 변위 등을 일으킬 수 있으며 심한 경우 구개의 흠 형성,절치의 결함 및 후천성 구개열 등을 야기할 수 있다. 본 증례는 치아가 맹출하기 전에 수차례의 기관 삽관을 시행한 병력이 있는 심한 저체중아에서 맹출지연,형태이상,법랑질 저형성,영구치 치배 등의 변위가 관찰되어 이를 보고하는 바이다. Delayed eruption and abnormal morphology of the primary incisors following intubation may be due to follicular displacement and localized trauma caused by the process of intubation. Result of such damage included palatal groove formation, defective incisors and acquired clefts. This clinical report presents effect of intubation on the primary dentition of premature low-birth-weight children prior to tooth eruption.

정향 수침액에 의한 아나필락시의 억제 효과

신태용,김상현,이석봉,엄동옥,임종필,이은희,김형민 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

The current study evaluates the capacity of Caryophylli Flos water extract(CFWE) to regulate immediate allergic reaction by control of histamine release. CFWE was found to exhibit a ingibitory activity on the compound 48/80-induced anaphylaxis. CFWE inhibited the serum histamine release induced in anaphylaxis by compound 48/80. CFWE was also showed a dose-depent activity on the conpound 40/80-induced histamine release from the highly purified population of Alcian Blue-positive peritoneal mast cells. This result suggest that CFWE may be useful for the prevention and treatment of allergy related disease.

계면활성제의 토양흡착에 대한 특성

신현무, 이상화 경성대학교 환경문제연구소 2000 環境硏報 Vol.10 No.1

Surfactant washing process being operated in ex-situ mode could be appropriate one of the most effective remediation alternatives for NAPLs(non-aqueous phase liquids) in soil. The adsorption of sufactants has been concern of the reduction of expenditure and the increase of efficiency. Through the result of estimating the extent of adsorption of surfactants to soils, notion sufactants showed higher adsorption to soils than anion surfactants. From the results of evaluating which model could explain the surfactant adsorption to soils, it was determined that anionic surfactants were described well with Langmuir adsorption isotherm model, while nonionic surfactants were with Freundlich model.

아로마요법이 수부 미세수술환자의 수면만족도, 통증 및 불안에 미치는 효과

신미영(외 4명) 신라대학교 (부산여자대학교) 2015 論文集 Vol.60 No.-

臨床檢體에서 分離된 E. coli의 臨床細菌學的 調査硏究

申鉉成,吳是煥,李敏雄 대한화학요법학회 1986 대한화학요법학회지 Vol.4 No.2

A total of 25004 cases of clinical materials from patients was collected in H hospital from January 1974 to December 1984 in Seoul. Among the materials, 7773 cases of the clinical specimens were identified as pathogenic, organisms. The numbers of cases of E. coli isolated from the specimens were 1838 except for cases of incubation of human feces. Infectious pattern and antibiotics sencitivity of the pathogenic organisms and E. coli were as follows: Total clinical specimens, and isolation rate of E. coli from total clinical materials and to the identified pathogenic organisms were increased more than 2 times in 1982 to 1984 comparing to the year in 1974 to 1976. The range of percentage of all identified microorganisms to total clinical specimens was 27.0~34.6% yearly. Isolated ratio E. coli to total specimens was 7.4% and the ration of isolated E. coli to total isolated pathogens was 23.6%(1838/7773). The isolation ratio of E. coli per each patient was 1.323 for male and 1.21 for female. The isolation ratio-of male to female was 1 : 1.88. The highest number of E. coli was found in May for male and June for female according to monthly isolation. On the other hand the lowest number of E. coli was observed in February for male and October for female respectively. In seasonal fluctuation of the isolated orgainsms from patients specimens, the isolation rate was maximized in fall for male, and in summer for female, but the ratio was generally decreased in winter season. The age specific isolation rate of E. coli was 27.8% under 10 year old group for male and 27.1% in 20~29 year old group for female, but the frequency of the organisms was observed lower in 10~19 year old group in both sexes. The isolating sources of specimens in male were 41% in pus, 22.2% in urine and 20.1% in throat swab, and the sources in female were 59.7% from urine, 14% in pus and 11.3% from vaginal discharge. The susceptibility to antibiotics studied for 11 years was all less than 40% in streptomycin, cephalothin, chloramphenicol, carbenicillin, tetracyclin, ampicillin, erythromycin and penicillin except for 73.6% in gentamicin and 52.8% in kanamycin. But in the last 2 years, the antibiotics showing over 90% sensitivity against E. coli were cefotaxime, sisomicin, cefoxitin, amikacin and pipemidic acid.

자동교시기능을 갖는 로봇의 3차원 오프라인 시뮬레이터 개발

신행봉,정동연,한성현 한국공작기계학회 2003 한국공작기계학회 춘계학술대회논문집 Vol.2003 No.-

We propose a unmaned integrating control system based-on Windows XP version Off-Line Programming System which can simulate a Robot model in 3D Graphics space in this paper. The industrial robot with 4 and 6 axes modeled SM5 and AMI respectively were adopted as an objective model. Forward kinematics, inverse kinematics and robot dynamics modeling were included in the developed off-line program. The interface between users and the off-line programming system in the Windows XP's graphic user interface environment was also studied. The developing language is Microsoft Visual C++. Graphic libraries, OpenGL, by silicon Graphics, Inc. were utilized for 3D Graphics.