Analytical Modelling and Simulation Analysis of Junctionless Nanotube (JL NT) MOSFET

Raj Kumar,Raj Kumar,Arvind Kumar 한국전기전자재료학회 2022 Transactions on Electrical and Electronic Material Vol.23 No.4

In this paper, an analytical model for junctionless nanotube (JLNT) MOSFET has been developed. The analytical model for minimum central potential, threshold voltage and drain current has been developed by using variable separation method. These model expressions are further applied to analyse the Short Channel Effects (SCEs) of JL NT MOSFET. The electrical performance of proposed device has been investigated by varying different process parameters such as silicon nanotube thickness, gate oxide thickness, and gate length. All the results of developed models have been validated by comparing with so obtained simulated results from genius 3D device simulator of VisualTCAD for different device parameters. JLNT MOSFET with appropriate design parameters can be further explored for circuit applications.

ON HARMONIC CONVOLUTIONS INVOLVING A VERTICAL STRIP MAPPING

Kumar, Raj,Gupta, Sushma,Singh, Sukhjit,Dorff, Michael Korean Mathematical Society 2015 대한수학회보 Vol.52 No.1

Let $f_{\beta}=h_{\beta}+\bar{g}_{\beta}$ and $F_a=H_a+\bar{G}_a$ be harmonic mappings obtained by shearing of analytic mappings $h_{\beta}+g_{\beta}=1/(2isin{\beta})log\((1+ze^{i{\beta}})/(1+ze^{-i{\beta}})\)$, 0 < ${\beta}$ < ${\pi}$ and $H_a+G_a=z/(1-z)$, respectively. Kumar et al. [7] conjectured that if ${\omega}(z)=e^{i{\theta}}z^n({\theta}{\in}\mathbb{R},n{\in}\mathbb{N})$ and ${\omega}_a(z)=(a-z)/(1-az)$, $a{\in}(-1,1)$ are dilatations of $f_{\beta}$ and $F_a$, respectively, then $F_a\tilde{\ast}f_{\beta}{\in}S^0_H$ and is convex in the direction of the real axis, provided $a{\in}[(n-2)/(n+2),1)$. They claimed to have verified the result for n = 1, 2, 3 and 4 only. In the present paper, we settle the above conjecture, in the affirmative, for ${\beta}={\pi}/2$ and for all $n{\in}\mathbb{N}$.

A novel method for controlled synthesis of nanosized hematite (α-Fe2O3) thin film on liquid-vapor interface

Kumar, Pawan,Singh, Raj Kumar,Rawat, Nitin,Barman, Partha Bir,Katyal, Subhash Chander,Jang, Hwanchol,Lee, Heung-No,Kumar, Rajesh Springer-Verlag 2013 Journal of nanoparticle research Vol.15 No.4

On harmonic convolutions involving a vertical strip mapping

Raj Kumar,Sushma Gupta,Sukhjit Singh,Michael Dorff 대한수학회 2015 대한수학회보 Vol.52 No.1

Let $ f_\beta=h_\beta+\overline{g}{_\beta}$ and $F_a=H_a+\overline{G}_a$ be harmonic mappings obtained by shearing of analytic mappings $$h_\beta+g_\beta={1}/{(2i{\sin}\beta)}\log\left({(1+ze^{i\beta})}/{(1+ze^{-i\beta})}\right),~0<\beta<\pi$$ and $H_a+G_a={z}/{(1-z)}$, respectively. Kumar \emph{et al.} \cite{ku and gu} conjectured that if $\omega(z)=e^{i\theta}z^n (\theta\in\mathbb{R},\,\, n\in \mathbb{N})$ and $ \omega_a(z)={(a-z)}/{(1-az)},\,a\in(-1,1)$ are dilatations of $f_\beta$ and $F_a$, respectively, then $F_a\widetilde\ast f_\beta \, \in S_H^0$ and is convex in the direction of the real axis, provided $a\in \left[{(n-2)}/{(n+2)},1\right)$. They claimed to have verified the result for $n=1,2,3$ and $4$ only. In the present paper, we settle the above conjecture, in the affirmative, for $\beta=\pi/2$ and for all $n\in \mathbb{N}$.

Novel chemical scaffolds of the tumor marker AKR1B10 inhibitors discovered by 3D QSAR pharmacophore modeling

Kumar, Raj,Son, Minky,Bavi, Rohit,Lee, Yuno,Park, Chanin,Arulalapperumal, Venkatesh,Cao, Guang Ping,Kim, Hyong-ha,Suh, Jung-keun,Kim, Yong-seong,Kwon, Yong Jung,Lee, Keun Woo Springer Science and Business Media LLC 2015 Acta pharmacologica Sinica. Vol.36 No.8

<P>Recent evidence suggests that aldo-keto reductase family 1 B10 (AKR1B10) may be a potential diagnostic or prognostic marker of human tumors, and that AKR1B10 inhibitors offer a promising choice for treatment of many types of human cancers. The aim of this study was to identify novel chemical scaffolds of AKR1B10 inhibitors using in silico approaches.</P>

In vitro antioxidant and free radical scavenging activities of stem extract of Euphorbia trigona Miller

Raj Kumar Salar,Pooja Sharma,Sukhvinder Singh Purewal 셀메드 세포교정의약학회 2015 TANG Vol.5 No.2

Antioxidative and free radical scavenging properties of different stem extracts of Euphorbia trigona were evaluated and correlated with its total phenolic content. Aqueous, acetone and methanolic extracts of shade dried stem were obtained and were concentrated in vacuo. The antioxidant and free radical scavenging activities of stem extracts was determined by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) scavenging assay, reducing power assay, deoxyribose degradation assay and Fe2+chelating assay. Total phenolic contents (TPC) were evaluated using Folin-Ciocalteu reagent. The results confirmed that the plant is a rich source of polyphenolic compounds which are invariably higher compared to other herbs. All extracts showed TPC in the range of 146.6 – 168.6 mg/g gallic acid equivalents at 300 µg/ml of extract. Among the three extracts ME showed highest scavenging activity as evidenced by maximum scavenging of DPPH (83.2%), OH• radicals (94.81%), Fe2+chelating activity (88.59%) and a high reducing power 0.623 at 300 µg/ml. Our results demonstrate that Euphorbia trigona, an unexplored xerophytic plant could be potential source of natural antioxidants and phytotherapeutic agents. The plant possess invariably high amount of polyphenolic compounds with a broad spectrum of antioxidant properties and could be further used for food, feed and pharmaceutical applications.

Modulation of Phenolic Content and Antioxidant Activity of Maize by Solid State Fermentation with Thamnidium elegans CCF 1456

Raj Kumar Salar,Milan Certik,Vlasta Brezova 한국생물공학회 2012 Biotechnology and Bioprocess Engineering Vol.17 No.1

Thamnidium elegans CCF 1456, a filamentous fungus, was used to enhance the total phenolic content and radical scavenging activity of maize via solid-state fermentation. Thamnidium fermented maize (TFM) and unfermented maize (UFM) grains were extracted with 65%ethanol and dimethylsulfoxide (DMSO). Total phenolic content (TPC), and radical scavenging capacity – determined with 1,1-diphenyl-2-picrylhydrazyl (DPPH) and radical cations of 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS•+) found for TFM – were significantly (P < 0.05) higher on the 5th day of incubation than that of UFM extracts. A linear correlation was observed among TPC, DPPH and ABTS scavenging activities, and also among TPC and various carbohydrate-cleaving enzymes (α-amylase, β-glucosidase and xylanase), suggesting that this? strategy may help to enrich? TFM with improved phytochemical properties and antioxidant activities. Thamnidium elegans CCF 1456, a filamentous fungus, was used to enhance the total phenolic content and radical scavenging activity of maize via solid-state fermentation. Thamnidium fermented maize (TFM) and unfermented maize (UFM) grains were extracted with 65%ethanol and dimethylsulfoxide (DMSO). Total phenolic content (TPC), and radical scavenging capacity – determined with 1,1-diphenyl-2-picrylhydrazyl (DPPH) and radical cations of 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS•+) found for TFM – were significantly (P < 0.05) higher on the 5th day of incubation than that of UFM extracts. A linear correlation was observed among TPC, DPPH and ABTS scavenging activities, and also among TPC and various carbohydrate-cleaving enzymes (α-amylase, β-glucosidase and xylanase), suggesting that this? strategy may help to enrich? TFM with improved phytochemical properties and antioxidant activities.

Tobacco Use Increases Oxidative DNA Damage in Sperm - Possible Etiology of Childhood Cancer

Kumar, Shiv Basant,Chawla, Bhavna,Bisht, Shilpa,Yadav, Raj Kumar,Dada, Rima Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.16

Background: Cigarette smoking and tobacco chewing are common modes of consuming tobacco all over the world. Parents need to be aware that germ cell integrity is vital for birth of healthy offspring as biological parenting begins much before birth of a child and even before conception. The present study was conducted to determine the etiology of non-familial sporadic heritable retinoblastoma (NFSHRb), by evaluating oxidative sperm DNA damage in fathers due to use of tobacco (smoking and chewing). Materials and Methods: We recruited 145 fathers of NFSHRb children and 53 fathers of healthy children (controls) in the study. Tobacco history was obtained by personal interview. Seminal reactive oxygen species (ROS) in semen, sperm DNA fragmentation index (DFI) and 8 hydroxy 2' deoxyguanosine (8-OHdG) levels in sperm were evaluated. The RB1 gene was screened in genomic blood DNA of parents of children with NFSHRb and controls. Odds ratios (ORs) derived from conditional logistic regression models. Results: There was significant difference in the levels of ROS (p<0.05), DFI (p<0.05) and 8-OHdG (p<0.05) between tobacco users and non-users. The OR of NFSHRb for smokers was 7.29 (95%CI 2.9-34.5, p<0.01), for tobacco chewers 4.75 (2.07-10.9, p<0.05) and for both 9.11 (3.79-39.2; p<0.01). Conclusions: This study emphasizes the adverse effect of tobacco on the paternal genome and how accumulation of oxidative damage in sperm DNA may contribute to the etiology of NFSHRb. In an ongoing parallel study in our laboratory, 11 of fathers who smoked underwent. Meditation and yoga interventions, showed significant decline in levels of highly mutagenic oxidised DNA adducts after 6 months. Thus our lifestyle and social habits impact sperm DNA integrity and simple interventions like yoga and meditation are therapeutic for oxidative damage to sperm DNA.

Estimation and validation of maxwell stress of planar dielectric elastomer actuators

Raj Kumar Sahu,Abhishek Saini,Dilshad Ahmad,Karali Patra,Jerzy Szpunar 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.1

In this paper, Maxwell stress of circular planar actuator at different applied voltages was estimated and then validated with the uniaxialcompression test of three different dielectric elastomers (VHB, silicone and natural rubber). Pelrine’s equation was revisited to estimateMaxwell stress which causes the actuation in the planar direction. More precise and accurate estimation of Maxwell stress could be madein this work by considering variation of dielectric constant with respect to frequency and pre-strain. Estimated Maxwell stress was validatedthrough (i) out-of-plane strain or thickness strain obtained from measured area strain considering constant volume deformation, and(ii) out-of-plane mechanical compressive test results. The estimated Maxwell stress agrees well with the corresponding experimentalcompressive stress values for different pre-straining cases considered in this work.

Impact of instream sand mining on habitat destruction or transformation using coupling models of HSI and MLR

Raj Kumar Bhattacharya,Nilanjana Das Chatterjee,Kousik Das 대한공간정보학회 2020 Spatial Information Research Vol.28 No.1

Several human activities like sand mining, dam construction have intensive effect on river ecosystem. Instream sand mining is one of them to hindrance on riverine biota. Hence, an attempt is made in this study to assess three tier habitat degradation or alteration caused by instream sand mining from channel bed to riparian and bank site in upper, middle and lower segments of Kangsabati River. Habitat Suitability Index (HSI) is applied to detect geo referenced ecological information on two different condition i.e. habitat suitability of two dominating species of Koeleria macrantha and Cynodon dactylon (pre mining) and degraded or altered habitat incorporated with mining responses (post mining). HSI prepared five different suitable class taken seven dominating variables i.e. river channel, sandchar, riparian zone, slope, elevation, dry and moist sand layer using multiple logistic regressions (MLR) under GIS platform. MLR denotes sandchar deposition, elevation as significant variables of Koeleriamacrantha dominance along the bank while moist sand layer, riparian zone signified on Cynodondactylon dominance across the riparian site. HSI indicates lowsuitable class of Koeleriamacrantha and Cynodondactylon dominated in largest sand mining area as lower (82%, 86%), middle (58%, 89%) and upper segment (77%, 78%) whereas largest mining area under two dominant species reaches low-suitable class as lower (79%, 58%), middle (89%, 82%) and upper segment (92%, 70%) respectively. In spite of variables influence on species dominance, massive sand mining leads to destroy the habitat suitability. Therefore, in situ habitat suitability of dominant species either degraded or altered throughout the channel.