Case report of cerebral creatine deficiency syndrome with novel mutation of SLC6A8 gene in a male child in Bangladesh

Rahman, Muhammad Mizanur,Fatema, Kanij Korean Society of Medical Genetics and Genomics 2021 대한의학유전학회지 Vol.18 No.1

Cerebral creatine deficiency syndrome (CCDS) is a disorder where a defect is present in transport of creatine in the brain. Creatine plays an essential role in the energy metabolism of the brain. This is a genetic disorder, autosomal recessive or X linked, characterized by intellectual disability, speech and language delay, epilepsy, hypotonia, etc. Until recently very few number of cases have been reported. Here we report a case of 1.5-year-old boy who had epilepsy (epileptic spasm and generalized tonic clonic seizure), intellectual disability, microcephaly, hypotonia and speech delay. His magnetic resonance imaging of brain showed cortical atrophy and electroencephalography showed burst suppression pattern. The diagnosis was confirmed by clinical exome sequencing which showed novel mutation of SLC6A8+ in exon 9, suggestive of X linked recessive CCDS. The patient was then treated with glycine, L-arginine and creatine monohydrate with multiple antiepileptic drugs.

Properties of Waterborne Polyurethane/CNT Nanocomposite Adhesives: Effect of Countercations

Rahman, Mohammad Mizanur,Hasneen, Aleya,Lee, Won-Ki,Kim, Han Do,Chun, Ho-Hwan,Shin, Hyun Woung,Yoon, Jeyong,Park, Hyun TAYLOR FRANCIS 2011 Journal of adhesion science and technology Vol.25 No.10

Effects of shrimp farming on local livelihoods and environment at the coastal area of Bangladesh

Rahman Md Mizanur,HyeonhoYun,Sungchul C. Bai 한국수산과학회 양식분과 2014 한국수산과학회 양식분과 학술대회 Vol.2014 No.7

Deformation and Stability Analysis of Embankment Foundation Soil Supported by DCM (Deep Cement Mixing) Columns and Geotextiles

Rahman, Md. Mizanur,이영대 한국방재학회 2012 한국방재학회논문집 Vol.12 No.3

This study is based on finite element analyses performed by PLAXIS code to investigate the feasibility of modeling the effect of DCM (Deep Cement Mixing) columns in two dimension by a newly proposed method namely ‘Replacement Weighted Area’. The results of new method have been compared with the existing method of ‘Same Area Replacement Ratio’ as well as with field observations. It has been found that the ‘Replacement Weighted Area’ in plane strain element has provided reasonable predictions. In addition, a parametric study of the stability of geotextile-reinforced soil was performed in different layers of embankment with factors like the effects of tensile stiffness, number and length of reinforced layer. It has been observed that vertical settlements and lateral displacements have been reduced with increasing in tensile stiffness, number and length of reinforcement. However, over certain thresholds, number and length of geotextile did not enhance significant settlements and lateral displacements. This study is based on finite element analyses performed by PLAXIS code to investigate the feasibility of modeling the effect of DCM (Deep Cement Mixing) columns in two dimension by a newly proposed method namely ‘Replacement Weighted Area’. The results of new method have been compared with the existing method of ‘Same Area Replacement Ratio’ as well as with field observations. It has been found that the ‘Replacement Weighted Area’ in plane strain element has provided reasonable predictions. In addition, a parametric study of the stability of geotextile-reinforced soil was performed in different layers of embankment with factors like the effects of tensile stiffness, number and length of reinforced layer. It has been observed that vertical settlements and lateral displacements have been reduced with increasing in tensile stiffness, number and length of reinforcement. However, over certain thresholds, number and length of geotextile did not enhance significant settlements and lateral displacements.

<i>Ferrimonas gelatinilytica</i> sp. nov., isolated from tidal flat sediment

Rahman, Mohammad Mizanur,Cha, Chang-Jun International Union of Microbiological Societies 2013 International journal of systematic and evolutiona Vol.63 No.11

<P>A novel beige-pigmented, Gram-staining-negative, coccoid, motile and facultatively anaerobic bacteria, designated strain CJ24<SUP>T</SUP>, was isolated from the tidal flat sediment of the Yellow Sea in South Korea. Characterization of this strain was performed on the basis of polyphasic taxonomic methods. Phylogenetic analysis of the 16S rRNA and g<I>yr</I>B genes revealed that strain CJ24<SUP>T</SUP> belongs to the genus <I>Ferrimonas</I>, sharing the highest 16S rRNA gene sequence similarity of 96.9 % with <I>Ferrimonas marina</I> DSM 16917<SUP>T</SUP>. Strain CJ24<SUP>T</SUP> was able to grow optimally at 30 °C, at pH 6.0 and in the presence of 2 % NaCl (w/v). As an isoprenoid quinone, menaquinone (MK-7) was predominantly identified from this strain, while ubiquinone (Q-7) was also present as a minor component. The DNA G+C content of strain CJ24<SUP>T</SUP> was 60.2 mol%. The most abundant cellular fatty acids were C<SUB>15 : 0</SUB> iso, C<SUB>18 : 1</SUB>ω9c, C<SUB>16 : 0</SUB> and C<SUB>17 : 0</SUB> iso. Therefore, strain CJ24<SUP>T</SUP> represents a novel species in the genus <I>Ferrimonas</I> for which the name <I>Ferrimonas gelatinilytica</I> sp. nov. is proposed; the type strain is CJ24<SUP>T</SUP> ( = KACC 17065<SUP>T</SUP> = JCM 18720<SUP>T</SUP>).</P>

Investigating Main Causes for Schedule Delay in Construction Projects in Bangladesh

Rahman, MD. Mizanur,Lee, Young Dai,Ha, Duy Khanh Korea Institute of Construction Engineering and Ma 2014 Journal of construction engineering and project ma Vol.4 No.3

Delay is the most common problem in the construction industry. It has many negative effects on project's success in terms of time, cost, quality, and safety. From the literature review, a total of thirty-five factors of delay were selected. These factors were divided into seven groups related to materials, manpower, owner, consultant, contractor, construction, and external problems. This study was carried out to identify the main causes of delay for a construction project through their importance level. The importance level was determined based on the frequency of occurrence and severity of impact. The structured questionnaire has distributed to the respondents who have much experience in construction management in Bangladesh. The results of analysis indicated that top five factors of construction delay according to their level of importance are: (1) price of construction materials increased very rapidly, (2) political situation (revolution/ public strikes), (3) shortages of skilled workers, (4) poor site management and supervision by contractor, (5) incompetent/ immature subcontractors. These findings of this study are expected to be significant contributions to Bangladesh construction industry in controlling current performance of project on time overrun.

Properties of Waterborne Polyurethane/Clay Nanocomposite Adhesives with Various Countercations of Carboxyl Acid Salt Group

Rahman, Mohammad Mizanur,Hasneen, Aleya,Lim, Kwon Taek,Lee, Jungun,Kim, Eun Young,Lee, Won-Ki TAYLOR FRANCIS 2011 Journal of Adhesion Science and Technology Vol. No.

Development of Time-Cost Models for Building Construction Projects in Bangladesh

Rahman, MD. Mizanur,Lee, Young Dai,Ha, Duy Khanh,Chun, Yong Hyun Korea Institute of Construction Engineering and Ma 2014 Journal of construction engineering and project ma Vol.4 No.3

Estimating time and cost is an important mission in the early phase of a construction project, especially in feasibility study. It provides a foundation for making decision whether or not the project is performed on schedule and within budget. Thus, reliability of this estimate plays a key role in measuring the success of a project. This study was carried out to investigate the time-cost relationship in building construction projects in Bangladesh. The mathematical equation used in this study is based on Bromilow's equation. The research data were collected from sixty-three completed building projects through questionnaire survey. Type of clients, type of projects, and tender methods are the project characteristics considered in this study. The results of analysis indicated that the Bromilow's time-cost (BTC) models developed for each project characteristic are appropriate due to quite high coefficient of determination and relatively small mean percent errors. Among them, the forecasted model for time and cost according to tender methods is the best fit model. It is concluded that the BTC model could be applied in building construction project to predict its time and cost in Bangladesh. Four different regression models were also developed in this study. The results of BTC model between some selected countries were compared to gain the comprehensive view.

Present Status of Rooftop Gardening in Sylhet City Corporation of Bangladesh: an Assessment Based on Ecological and Economic Perspectives

Rahman, Md. Habibur,Rahman, Mizanur,Kamal, Md. Mostafa,Uddin, Md. Jasim,Fardusi, Most. Jannatul,Roy, Bishwajit Institute of Forest Science 2013 Journal of Forest Science Vol.29 No.1

Present study analyzes the rooftop gardening status, floristic composition and cost and return of the rooftop garden in Sylhet City Corporation of northeastern Bangladesh. Data was collected from 450 rooftop gardeners randomly during July-September 2010. Study reveal that rooftop gardening is generally for mental satisfaction (95.3%) followed by leisure time activity (87.8%) in the study area and almost all the family members of gardeners' were involved; while collection of planting materials, sites preparation and marketing of products were reported to be carried out by males only (male 71.33%). Middle income classes were most interested in rooftop gardening (43.78%). The survey recorded 53 plant species (35 families) of which Cucurbitaceae family represented highest eight species. Shrubs (28%) were highest followed by herbs (26%) among agri-crops (36%) and flower species (30%). About 89% of the rooftop gardeners procured planting materials from nursery, market, fair, neighbor, relative and friends and they mostly prefer to use seedlings (48%) for roof gardening followed by direct seed sowing (21%). Gardeners sell products sporadically in different local markets, directly or through intermediaries, with no uniform pricing for system. Rooftop gardening improves the food security and meet nutritional deficiency to the gardeners. Survey revealed that generally very few people consider rooftop gardening commercially to get profit and from the cost-return analysis this gardening system can be economically viable if proper and scientifically managed. The study conclude that active government and NGOs could play vital role to increasing this activities by providing training and motivate people with technical aspects of rooftop gardening.

Myocardial Calcification and Hypertension following Chronic Renal Failure and Ameliorative Effects of Furosemide and Captopril

Rahman, Mizanur,Kim, Shang-Jin,Kim, Jin-Shang,Kim, Sung-Zoo,Lee, Young-Up,Kang, Hyung-Sub S. Karger AG 2010 Cardiology Vol.116 No.3

<P><I>Objectives:</I> The aim of this study was to prevent metastatic myocardial calcification and hypertension following chronic renal failure (CRF). <I>Methods:</I> A total of 50 male Sprague-Dawley rats were allocated to one of five groups: the control group (sham), the NxNT group (nephrectomized rats receiving no treatment), the NxFuro group (nephrectomized rats treated with furosemide), the NxCap group (nephrectomized rats treated with captopril) and the NxFuroCap group (nephrectomized rats treated with furosemide and captopril). Surgery (5/6 nephrectomy) was performed to induce CRF. Oral treatment with furosemide (20 mg/kg) and/or captopril (0.05 mg/kg) was given twice daily for 5 weeks. Parameters were studied after 5 weeks. <I>Results:</I> In the NxNT group, arterial blood pressure was significantly increased compared with the controls. Monotherapy with furosemide or captopril and both in combination maintained blood pressure to near or below control. Myocardial and remnant-kidney calcification was detected in NxNT rats, but calcification was absent in the NxFuroCap rats. Cardiac hypertrophy and fibrosis was observed in the NxNT group but not in treatment groups. Both plasma inorganic phosphate and Ca<SUP>2+</SUP> significantly increased in the NxNT group, but the difference was not significant in the treatment groups. <I>Conclusion:</I> Furosemide, either alone or in combination with captopril, is capable to prevent myocardial calcification, cardiac hypertrophy and hypertension, maintaining blood Ca<SUP>2+</SUP> and phosphate levels by slowing CRF.</P><P>Copyright © 2010 S. Karger AG, Basel</P>