화물운송서비스의 아웃소싱전략 및 발전방향에 관한 연구

임홍상,국우각,강경우 한국로지스틱스학회 2002 로지스틱스연구 Vol.10 No.2

인천국제공항의 개항과 남북경협을 통한 동북아 물류중심국가로 발전하기 위하여 노력을 기울이고 있는 우리나라는 현재 물류에 대한 관심이 그 어느 때보다 높게 나타나고 있으며, DHL, UPS 같은 국제적인 전문 물류업체는 최첨단 물류정보시스템과 자산을 가지고 적극적인 국내 마케팅활동을 벌이고 있다. 우리나라의 경우 IMF라는 국가적 불황을 겪게 되면서 물류 아웃소싱에 대해 그 인식이 크게 제고되었으며, 과거 규모 위주의 성장을 추구했던 것에서 벗어나 수익성·차별성을 추구하면서 기업을 경영하는 풍토가 조성되었다. 하지만 이러한 특수성은 외국에서 나타난 아웃소싱의 순효과 외에 단순한 구조조정의 수단으로 이용되어 물류기능의 고도화가 이루어지지 않았다는 지적은 우리나라 물류아웃소싱의 방향설정 및 물류전략설정에 있어 많은 관심과 지속적인 노력을 기울여야 한다는 것을 의미한다. 본 연구는 국내 수배송 전문업체의 바람직한 마케팅전략을 세우는데 그 목적이 있었으며, 이를 시장 즉, 화주측면에서 접근하였으며, 로지스틱 판별분석을 이용하여 수배송 아웃소싱을 도입하고 있는 기업과 도입하지 않은 업체에 대해 분석을 실시하였다. 분석결과 물류 정보서비스의 활용 및 선호도가 높을수록, 화물의 시간가치가 높을수록, 공차거리율 및 적재율의 정기적인 측정이 이루어질수록, 제품의 출하빈도가 높을수록, 통행특성에 있어 TL 보다는 LTL 일수록 수배송 아웃소싱을 선호하는 것으로 나타났다. 특히, 국내의 제3자 물류공급업체 및 화물운송업체의 경우 상대적으로 물류정보시스템에 대한 중요도 및 위탁업체와의 상호 호환성에는 그 중요도가 낮은 것으로 나타나 본 연구의 분석결과에 비추어 볼 때 하루바삐 인식의 전환 및 구축이 필요할 것이라 판단된다. Recently, Korea has a great concern of the logistics. Expecially opening of the Incheon International Airport and planning for a major role in logistics in the East-Asia region through improving in inter Korean relation accelerate their logistics concern. Futhermore, international freight delivery service provider such as DHL & UPS sales positively with their state of arts logistics information services and asset. In case of Korea, many company managed from the pursuit of scale economy to focus on a core business and cost saving as recognized for outsourcing of the logistics function when the economy of Korea was under an IMF bailout program. However, their point of view is not by positive effects such as specific competitive power of speciality but used of reshaping in labour force. The objective of this study is build a marketing strategies of freight delivery service in Korea. Particularly, this study is by Logistics Discrimination analysis between those who shipper with outsourced their delivery service and are not. As the result of analyzing outputs from Logistics Discrimination model, those who more used outsourced in freight delivery service when delivery service are the more employing information services related to logistics such EDI etc, handle with higher value of time(VOT) in freight, regularly check up the rate of travels with(without) freight, the shipment is more frequent, and less than truck-load(LTL) in trip characteristics.

강의 현대화 추진 및 활용방안 연구

구경완,이근복,장종국,김재홍,김영환,최제영,이승훈 永同大學校 1997 硏究論叢 Vol.3 No.1

본 연구는 각종 첨단 기자재를 활용한 강의 현대화 방안을 모색함으로서 공학교육의 효율성을 도모하고 학생들의 학습동기를 유발하여 창조적 능력을 갖츤 전문기술 인력을 양성하는 데 도움을 주고자 하는 것이다. 이를 위하여 현행 공학교육의 현황과 문제점을 분석하고 강의 현대화 사례를 조사하여 본 연구의 기초자료로 삼고자 하였으며, 학부·전공별 강의 현대화 추진 실태분석 및 개선방안을 모색한 후 이상의 연구결과를 종합하여 향후의 강의 형대화 추진방향을 걸정하였다. This study aims to help bring up the well-skilled and creative engineers by searching the modernization of education using various high technology facilities. For this, we analyzed the general condition and problems of current engineering education and surveyed the case study of the modernization of education as basic study. After analyzing the existing situation of promotion searching the proper improvement methods of it, we proposed the new direction of the modernization of education from now on.

DESMOPLASTIC AMELOBLASTOMA의 치험 1례

김성국,신홍인,박희경,장현중,김영미,김진수 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1

Ameloblastomas are benign epithelial neoplasm of the jaw comprising approximately 1-3.3% of all odontogenic cysts and tumors. Although most are microscopically benign, they are generally considered to be locally aggressive and destructive, exhibiting a high rate of recurrence. Treatments of them contain the conservative treatments on unilocular types and radical treatments on multilocular types. Classifications based on the histologic features of ameloblastoma generally included the follicular, plexiform, acanthomatous, basal cell, uncystic types. However, recantly a new and unusual variant has been added by Eversole et. al in 1984, the histologic features of which are characterized by marked stromal desmoplastic proliferation. This is a case report of desmoplastic ameloblastoma in the anterior maxilla of 63 year-old female treated by block excision. THis provides a brief review of the literature because of the rarity and unusual radiographic-histologic features of desmoplastic ameloblastoma.

KHFe(CO)_4-HCHO系를 利用한 Nitro 및 Nitroso化合物의 환원 N-메칠화 반응

沈相喆,閔庚隱,嚴在國,洪錫 경북대학교 1978 논문집 Vol.10 No.-

The reduction of nitro and nitroso compounds using tetracarbonylhydridoferrate-formaldehyde under mild conditions (at room temperature and then 60℃ under CO) gives the corresponding N, N-dimethylation via N-methylation in good to excellent yields. The reaction mechanism via immonium salt is assumed.

골수구성 백혈병 환자에게 발생한 결핵성 림프절염

이창섭,송진수,최평균,조재현,방지환,박경화,박완범,김홍빈,김남중,윤성수,박선양,김병국,오명돈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.5

혈액질환 가운데 결핵 발생이 증가한다고 알려진 것은 호지킨 림프종을 포함한 림프증식성질환 그리고 모양세포성 백혈병 등이 있다. 또한 동종 골수이식을 받은 환자에서도 결핵은 증가한다고 알려져있다. Kaplan 등은 골수구성 백혈병 환자에서 결핵 발생이 증가한다고 보고하였다. 그러나 골수구성 백혈병 환자에서 결핵의 발생이 증가하는 이유에 대해서는 아직까지 정확하게 밝혀지지 않았다. 저자들이 2년 동안 후향적으로 조사한 180명의 성인 골수구성 백혈병 환자들 가운데 결핵이 발생한 환자는 4명이었고, 발생 부위는 모두 림프절이었다. 결핵은 골수구성 백혈병의 특정 아형에만 국한되어 발생하지 않았지만, 50%에서 FAB 분류에 의한 M4였다. 림프절이 종대된 골수구성 백혈병 환자에서 특히, 결핵의 유병율이 높은 나라에서는 결핵성 림프절염도 감별진단에 포함시켜야 한다. During the neutropenic phase, leukemia patients receiving chemotherapy are prone to bacterial and, fungal infections; occasionally mycobacterial, viral and protozoal organisms may also cause infections. Mycobacterium tuberculosis infection was reported very rarely in these patients. This report describes four patients with M. tuberculosis infection identified from 185 adult patients who were diagnosed myelogenous leukemia between January 2003, and December 2004. There was no patient with M. tuberculosis infection from 44 lymphoid leukemia and 11 acute biphenotypic leukemia patients. Sites of infection were all lymph nodes. Three among four patients were presented with lymphadenopathy at initial diagnosis of leukemia, and the other one presented with lymphadenopathy after induction chemotherapy. There was no patient presented with lymphadenopathy during the neutropenic phase. Tuberculous lymphadenitis was presented in a patient with three acute myelogenous leukemia (FAB class 2 M4, 1 M2) and a chronic myelogenous leukemia, accelerated phase. An acute myelogenous leukemia patient had a leukemic cell and tubercle bacilli in the same lymph node. Tuberculosis should also be included as a differential diagnosis in myelogenous leukemia patient with lymphadenopathy, especially in the countries in which the disease is endemic.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

The Effect of TNF-α and INF-γ on the Telomerase Activity of Cultured Human Keratinocyte

Hong, Kyung-Kook,Lew, Bark-Lynn,Kim, Young Il,Lee, Jin-Woo,Kim, Nack-In WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2007 東西醫學硏究所 論文集 Vol.2007 No.-

Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation and abnonnal differentiation of the lesional epidermis. In pathogenesis, inflammatory cytokines such as TNF-α and IFN-8 from infiltrated T-cells seem to act a central role. Although many chronic inflammarory conditions can lead to cancer development. there is no evidence of increased incidence of cancer in psoriatic s kin lesion. Telomerase is an enzyme-reverse transcriptase that protects chromosomes from degradation by stabilizing telomere length. Recent studies suggest that telomerase activity may be responsible for some part of nonmalignant prohferatory skin disease. In addition, there is evidence that telomerase activity is related with proliferation and differentiation of keratinocyte. In this experiment, we tried to evaluate the effect of TNF-α and TFN-8 to the telomerase activity and its differential effect thought the passage. The results showed increased telomerase activity according to stimulation and this extent was different from the various passage. These results suggest that the key cytokines of psoriasis, namely, TNF-α and TFN-8 increase telomerase activity at proliferative cells, which could contribute to hyperproliferation and abnormal differentiation of lesional keratinocyte. Moreover, this increased telomerase activity could partially explain the cancer incidence of psoriasis that is not increased compared to the normal population.

The Effect of TNF-α and INF-γ on the Telomerase Activity of Cultured Human Keratinocyte

( Kyung Kook Hong ),( Hee Ryung Cho ),( Ki Heon Jeong ),( Yun Seok Yang ),( Bark Lynn Lew ),( Jin Woo Lee ),( Nack In Kim ) 대한피부과학회 2007 초록집 Vol.45 No.20

The Effect of TNF-α and INF-γ on the Telomerase Activity of Cultured Human Keratinocyte

( Kyung Kook Hong ),( Bark Lynn Lew ),( Young Il Kim ),( Jin Woo Lee ),( Nack In Kim ) 대한피부과학회 2007 Annals of Dermatology Vol.19 No.4

Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation and abnormal differentiation of the lesional epidermis. In pathogenesis, inflammatory cytokines such as TNF-α and IFN-γ from infiltrated T-cells seem to act a central role. Although many chronic inflammatory conditions can lead to cancer development, there is no evidence of increased incidence of cancer in psoriatic skin lesion. Telomerase is an enzyme-reverse transcriptase that protects chromosomes from degradation by stabilizing telomere length. Recent studies suggest that telomerase activity may be responsible for some part of nonmalignant proliferatory skin disease. In addition, there is evidence that telomerase activity is related with proliferation and differentiation of keratinocyte. In this experiment, we tried to evaluate the effect of TNF-α and IFN-γ to the telomerase activity and its differential effect thought the passage. The results showed increased telomerase activity according to stimulation and this extent was different from the various passage. These results suggest that the key cytokines of psoriasis, namely, TNF-α and IFN-γ increase telomerase activity at proliferative cells, which could contribute to hyperproliferation and abnormal differentiation of lesional keratinocyte. Moreover, this increased telomerase activity could partially explain the cancer incidence of psoriasis that is not increased compared to the normal population. (Ann Dermatol (Seoul) 19(4) 147~152, 2007)

A Study on Altered Expression of Serine Palmitoyltransferase andCeramidase in Psoriatic Skin Lesion

Kyung-Kook Hong,Hee-Ryung Cho,Won-Chul Ju,Yunhi Cho,Nack-In Kim 대한의학회 2007 Journal of Korean medical science Vol.22 No.5