http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Dialogues and Debates in Dermatology (DDD 1) : Which is the best option? To treat ASAP vs wait & see
정기양 ( Kee Yang Chung ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Actinic keratosis (AK) is a precancerous lesion caused by chronic exposure to ultraviolet light. It is known to occur mainly in Caucasians but the incidence in Korea is known to increase as well. Not all AKs progress into squamous cell carcinoma (SCC) but approximately 90% of SCCs have contiguous AKs which is consistent with the perception that SCCs are preceded by AKs. A study found that up to 60% of SCCs arise directly from an AK and another study showed that 136 of 165 SCCs have close relationship to AKs. Of these SCCs, 26.7% were seen to have occurred directly from an existing AKlesion and 55.7% were closely situated to an AK lesion. How much of the AKs actually progress into invasive SCCs is not yet known with certainty but the range is known to be anywhere from 0.075% to 16% or even more. This means that the majority of AKs remain stable or they may even regress. A review found that annual rates of regression for a single AK to be 15% to 63% with recurrence rates of 15% to 53%. These clinical data are not conclusive and it is still impossible to predict which AK will progress into an invasive SCC and which will regress. This uncertainty has ignited much discussion regarding the best treatment approach for AKs, with some encouraging careful follow up and others claiming aggressive approach.
Melanoma surgery and NPWT as a reconstruction option
정기양 ( Kee Yang Chung ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Melanoma in dark-skinned individuals often develops in an acral lentiginous fashion on the foot and wide excision usually results in a substantial defect. Various repair methods including distant flap, full-thickness skin graft and secondary intention healing (SIH) are used to repair these defects. Recently, use of negative pressure wound treatment (NPWT) has been shown to accelerate wound healing in different types of wounds. We have retrospectively compared the functional and cosmetic results of NPWT and SIH in 22 patients who underwent wide excision of melanomas on the foot. The defects of 13 patients were healed by secondary intention (SIH group) and 9 using negative pressure wound treatment (NPWT group). There was no significant difference in time to complete wound healing between the two groups. However, evaluation using Vancouver Burn Scar Assessment Scale of Scars at time of complete healing showed that the mean value of NPWT group was significantly lower than that of the SIH group. The NPWT group also had significantly better results than the SIH group for total score, vascularity, and height of the scars. As for complications, no wound infection was encountered in NPWT group, whereas 8 of 13 patients in SIH group were found to be affected by wound infection in the course of treatment despite frequent and meticulous aseptic dressing changes. These results show that, despite the drawback of rather prolonged healing time, NPWT is an excellent therapeutic option for post-wide excision wounds on feet with acceptable functional and cosmetic outcomes.
항보체 간접 면역형광법을 이용한 조직내의 Treponema pallidum 검출에 관한 연구
정기양(Kee Yang Chung),이민걸(Min Geol Lee),이정복(Jung Bock Lee) 대한피부과학회 1987 대한피부과학회지 Vol.25 No.4
Using the FTA-ABS complernent test, 32 skin speciruens from 27 patients with primary and secondary syphilis and a stomach specimen from a patient with suspected gastric syphilis which were confirmed by clinical history, physical examination, VDRL, FTA-ABS, and 19S(IgM)-FTA test, were tested. The following results were obtained. 1. In the darkfield examination, 7 of the 9 specimens(78%) were positive and in the FTA-ABS complernent test, 20 of the 33 specimens(61%) were positive. 2. The ratio of agreement between the darkfield examination and the FTA- ABS complement test was 89%. 3. In the chancres, macular syphilids, and condyloma lata, T. pallida were diffusely scattered in the epidermis, dermoepidermal junction, connective tiasue, and vascular walls, whereas in the papular syphilid T. pallida were mainly aggregated in the the epidermis, dermoepidermal junction, papillary dermis as well as the blood vessel walls in the papillary dermis. From these results, the FTA-ABS complement test can be considered to be a useful method for both the diagnosis and research of syphilis. It is especially helpful in cases where serological or histopathological study can not confirrn the diagnosis as when internal organs are involved.