급성 기관지염에 대한 Cefaclor의 치료 효과

박순규,여동승,이수걸,최광웅,이중길,신영기 최신의학사 1992 最新醫學 Vol.35 No.11

乳酸菌 變異株의 誘導와 利用(第1報) : Nitrosoguanidine에 依한 乳酸菌 變異株의 誘導 Induction of Lactic Acid Bacteria Mutants by Nitrosoguanidine

朴啓仁,愼重燁 경희대학교 부설 식량자원개발연구소 1986 硏究論文集 Vol.7 No.-

Two strains of Lactobacillus acidophilus NRRL B-2178 and Lactobacillus plantarum ATCC 8014 were treated with N-methyl-N-nitro-N-nitrosoguanidine(NTG). In case of Lactobacillus acidophilus NRRL B-2178, 71 possible mutants were isolated. There was considerable variation among mutants in acid production and relative amounts of volatile compounds of soy milk prepared from soy protein isolate. LaHA-6 which was excellent in acid production and relative amounts of volatile compounds was found to possess stable characters after 20 daily transfer in MRS broth. In case of Lactobacillus plantarum ATCC 8014, 44 possible mutants were isolated. There was considerable variation among mutants in acid and CO_(2) production of modified Eliiker's broth medium and MD broth medium, respectively. LpLA-10 which produced lower amounts of acid and higher amounts of CO_(2) was found to possess stable characters after 20 daily transfer in MRS broth.

Tenax-GC를 利用한 大豆乳와 醱酵大豆乳의 風味成分 分析

愼重燁,李瑞九,金顯五,朴啓仁 경희대학교 부설 식량자원개발연구소 1987 硏究論文集 Vol.8 No.-

Soy milk prepared from soy protein isolate and soy milk fermented with Lactobacillus acidophilus were adsorbed and desorbed by using Tenax-GC method and analyzed by Gas Chromatograph. It was found that this techingue was very efficient when the analytical results was expressed by the ratis of the peak area of each volatile to that of a fixed concentration of internal standard. Acetaldehyde, ethyl vinyl ketone, n-hexanal, n-hexanol, and 1 -octen-3-ol existed in soy milk. The content of acetaldehyde and diacetyl was increased while that of n-hexanal was reduced by lactic fermentation.

Lactobacilli의 Lysine Analog 내성 변이주에 의한 Lysine 생산

신중엽,박계인,이종대 慶熙大學校 1985 論文集 Vol.14 No.-

S-2-Aminoethyl L-Cysteine(ABC), and analong of L-lysine, significantly inhibited the growth of wild type strains of Lactobacillus acidophilus IFO 3205, Lactobacillus acidophilus IFO 13952, Lactobacillus bulgaricus ATCC11842, and Lactobacillus bulgaricus IFO 353g. The growth inhibition of these strains depended on AEC concentration. In presence of 10ug/ml of AEC concentration the growth of these strains was inhibited completely. AEC resistant mutants were induced by N-methyl-N-nitro-N-nitrosoguanidine(NTG) and Ethylmethane sulfonate(EMS) treatment. Almost all resistant mutants produced lysine. Lysine productivity of mutants had no insignificant relation to method of mutagen treatment. Also lysing productivity of mutants had nothing to do with concentration of AEC. Lysince productivity of lysine analog resistant mutants obtained from first mutation was increased by further mutation. Among the AEC resistant mutants, LaNA-412 was selected as lysine producing mutant. LaNA-412 produced 103 ug/ml L-lysine.

23년간 서울 지역 초˙중˙고등학생의 비만 추이

박영신,이동환,최중명,강윤주,김종희 대한소아과학회 2004 小兒科 Vol.47 No.3

韓國大豆食品의 Oligo糖 消長에 關한 硏究

朴啓仁,愼重燁,金鍾國 慶熙大學校 1983 論文集 Vol.12 No.-

Three Korean variety of soybeans and five ordinary fermented soybean pastes collected from 5 districts were studied for oligosaccharides. Oligosaccharides in soybean (Bong Eui Variety), meju, and fermented soybean pastes were determined. The changes of oligosaccharides during the meju preparation were investigated. And then oligosaccharides hydrolyzing microorganism was isolated and indentified. The results obtained are as follows: 1) All of the three Korean variety of soybeans were detected for sucrose, raffinose, and stachyose. In case of five ordinary fermented soybean pastes, three samples collected from Seoul, Busan, and Deagu were detected for sucrose, the only one sample collected from Busan was detected for traces of raffinose and stachyose, and the rest was not detected for these oligosaccharides. 2) Bong Eui variety of soybean contained 42.3㎎/g of sucrose, 12.5㎎/g of raffinese, and 32.5㎎/g of stachyose. Meju contained 2.48㎎/g of sucrose, 0.01㎎/g of raffinose, and 0.03㎎/g of stachyose. And then fermented soybean paste contained 0.25㎎/g of sucrose. 3) As the result of steeping and cooking the soybean, the contents of sucrose, raffinose, and stachyose in soybean decreased to 66.9%, 72% and 69.5% respectively. 4) Oligosaccharides in cooked soybean decreased a little at early stage of fermentation and almost disappeared except sucrose in 40 days. 5) Oligosaccharides hydrolyzing bacteria, strain B-12 was isolated from meju and identified as Bacillus up.

乳酸菌 變異株의 誘導와 利用(第1報) : Nitrosoguanidine에 依한 乳酸菌 變異株의 誘導 Induction of Lactic Acid Bacteria Mutants by Nitrosoguanidine

朴啓仁,愼重燁 慶熙大學校 1986 論文集 Vol.15 No.-

Two strains of Lactobacillus acidophilus NRRL B-2178 and Lactobacillus plantarum ATCC 8014 were treated with N-methyl-N-nitro-N-nitrosoguanidine(NTG). In case of Lactobacillus acidophilus NRRL B-2178, 71 possible mutants were isolated. There was considerable variation among mutants in acid production and relative amounts of volatile compounds of soy milk prepared from soy protein isolate. LaHA-6 which was excellent in acid production and relative amounts of volatile compounds was found to possess stable characters after 20 daily transfer in MRS broth. In case of Lactobacillus plantarum ATCC 8014, 44 possible mutants were isolated. There was considerable variation among mutants in acid and CO_2 production of modified Elliker's broth medium and MD broth medium, respectively. LpLA-10 which produced lower amounts of acid and higher amounts of CO_2 was found to possess stable characters after 20 daily transfer in MRS broth.

韓國大豆食品의 Oligo糖 消長에 關한 硏究

朴啓仁,愼重燁,金鍾國 경희대학교 부설 식량자원개발연구소 1983 硏究論文集 Vol.4 No.-

Three Korean variety of soybeans and five ordinary fermented soybean pastes collected from 5 districts were studied for oligosaccharides. Oligosaccharides in soybean (Bong Eui Variety), meju, and fermented soybean pastes were determined. The changes of oligosaccharides during the meju preparation were investigated. And then oligosaccharides hydrolyzing micro-organism was isolated and identified. The results obtained are as follows: 1) All of the three Korean variety of soybeans were detected for sucrose, raffinose, and stachyose. In case of five ordinary fermented soybean pastes, three samples collected from Seoul, Busan, and Daegu were detected for sucrose, the only one sample collected from Busan was detected for traces of raffinose and stachyose, and the rest was not detected for these oligosaccharides. 2) Bong Eui variety of soybean contained 42.3㎎/g of sucrose, 12.5㎎/g of raffinese, and 32.5㎎/g of stachyose. Meju contained 2.48㎎/g of sucrose, 0.01㎎/g of raffinose, and 0.03㎎/g of stachyose. And then fermented soybean paste contained 0.25㎎/g of sucrose. 3) As the result of steeping and cooking the soybean, the contents of sucrose, raffinose, and stachyose in soybean decreased to 66.9%, 72%, and 69.5% respectively. 4) Oligosaccharides in cooked soybean decreased a little at early stage of fermentation and almost disappeared except sucrose in 40 days. 5) Oligosaccharides hydrolyzing bacteria, strain B-12 was isolated from meju and identified as Bacillus sp.

Lactobacilli의 Lysine Analog 내성 변이주에 의한 Lysine 생산

신중엽,박계인,이종대 경희대학교 부설 식량자원개발연구소 1985 硏究論文集 Vol.6 No.-

S-2-Aminoethyl L-Cysteine(ABC), an analog of L-lysine, significantly inhibited the growth of wild type strains of Lactobacillus acidophilus IF0 3205, Lactobacillus acidophilus IF0 13952, Lactobacillus bulgaricus ATCC 11842, and Lactobacillus bulgaricus IF0 353g. The growth inhibition of these strains depended on AEC concentration. In presence of l0ug/ml of AEC concentration the growth of these strains was inhibited completely. AEC resistant mutants were induced by N-methyl-N-nitro-N-nitrosoguanidine(NTG) and Ethylmethane sulfonate(EMS) treatment. Almost all resistant mutants produced lysine. Lysine productivity of mutants had no insignificant relation t o method of mutagen treatment. Also lysine productivity of mutants had nothing to do with concentration of AEC. Lysine productivity of lysine analog resistant mutants obtained from first mutation was increased by further mutation. Among the AEC resistant mutants, LaNA-412 was selected as lysine producing mutant. LaNA-4 12 produced 103μg/ml L-lysine.

고성능 표면탄성파 필터의 최적 설계에 관한 연구

신양호,김귀현,이진복,엄현석,이중근,박진석 漢陽大學校 工學技術硏究所 1999 工學技術論文集 Vol.8 No.1

본 논문에서는 고성능 표면탄성파 필터의 최적 설계를 위하여 다양한 IDT(interdigital transducer) 구조의 필터를 제작하고 각각의 주파수 응답특성을 비교 분석하였다. 기본 구조외에 MSC(micro strip-coupler), double split, reflector, ground line 등의 구조를 일반적으로 널리 사용되고 있는 Y-Z cut l-N(LiNbO3) 기판 위에 형성시켰다. 제작된 소자의 중심주파수, 통과 대역, 삽입손실등을 측정하였으며, 주파수 응답에 기초한 기존 모델의 효용성을 논의하였다. Effects of IDT structures on frequency responses of SAW filters are investigated to achieve a high performance SAW filter, Various types of IDTS, such as MSC(multistrip-coupler), double split, reflector, and ground line, are designed and patterned on a widely used Y-Z cut LN(LiNbO3) substrate. Center frequencies, band widths, and insertion losses are measured and compared. Invalidity of the conventional model based on the impulse response model is also discussed.