자살 시도에 영향을 미치는 정신사회적 요인

허지원,최광연,이분희,심세훈,양종철,김용구 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.2

Objectives : A lots of studies have investigated the psychosocial characteristics of suicidal attempters in order to find eff-cient coping strategy and treatment intervention. The purpose of this study was to examine the psychosocial factors affecting the suicide attempt in psychiatric patients. Methods : Two hundred eighty patients who attempted suicide and admitted in the emergency room in 3 university hospitals from December 2003 to May 2006 were recruited in this study. The patients were interviewed using Structured Clinical Inter-view for DSM-IV Axis I disorder (SCID-RV), Lethality of Suicide Attempt Ratings Scale (LSARS) and Risk-Rescue Rating system (RRR). Results : The suicide attempters have psychosocial characteristics of female preponderance, age 20-39, high school in educational level, married in marriage condition, inoccupation, house makers in occupation. Most of attempters used the non-severe methods such as drug ingestion or wrist cutting, and selected home as the place of attempt. The delay until discovery was less than 4 hours for most suicide attempters, and the rate of asking for help directly or dropping clues were high. Major depressive disorder was the most common psychiatric illness among attempters. Conclusions : The present study would be the early stage to explore the risk factor and protect factor of suicidal attempt. This study suggests that the closed observation to potential-suicidal attempter in daily life is critical to protect against the fatal results due to suicidal attempts.

폐지 소각 공정의 전과정평가

정수정,류지연,허탁 한국전과정평가학회 2004 한국전과정평가학회지 Vol.5 No.1

본 연구에서는 전과정평가(Life Cycle Assessment, LCA)기법을 이용하여 폐지 소각 공정에 대한 전과정영향평가를 수행하였다. 폐지 1kg을 소각할 경우, 전력 0.089kwh, 용수 0.86kg, 각종 화학약품 0.0086kg이 투입되고 대기배출물로 이산화탄소는 1.13kg, NOx는 0.0015kg 발생되고 바닥재와 비산재는 각각 0.1kg, 0.013kg 발생하며 폐열을 이용한 스팀 에너지 3.42MJ이 회수된다. 소각 공정 자체에 의한 이산화탄소 배출은 1.13kg/f.u.이며 에너지 회수로 인하여 0.32kg/f.u.가 환경 이득이 되어 최종적으로 0.82kg /f.u.의 이산화탄소가 발생한다. 전과정 영향평가 결과, 지구온난화가 77.7%, 자원고갈 6.3%, 산성화, 부영양화, 생태독성 순으로 조사되었다. 이산화탄소의 주원인인 탄소함량을 줄이면 환경영향이 줄어들 수 있으나 일반적인 종이의 탄소함량은 일정하므로 이는 해결방안으로 적절치 못하다. 그렇다면 폐열 에너지 회수율을 높이는 것이 전체 환경부하 저감에 도움이 될 것이다. 회수율을 높이는 방안으로는 수분함량을 줄이는 것, 즉 폐지와 함께 섞여 들어오는 음식물 쓰레기의 양을 줄이면 에너지 회수율을 좀 더 증가시켜 환경부하를 저감하는 하나의 방안이 될 것이다. 또한 보다 근본적인 해결방안으로는 되도록이면 현재 56% 정도인 폐지의 재활용률을 높여 폐지소각으로 인한 환경부하 발생을 감소시켜야 할 것이다. This study is about practicing LCA on the incinerating waste paper. One kilogram of waste paper needs a 0.089kwh of electricity, 0.86kg of water and 0.0086kg of various chemicals while burned. As a result, 1.13kg of CO2, 0.0015kg of NOx are eliminated as the outcome to the air. Also, 0.1kg of ashs and 0.013kg of arsenic acids are produced. Steam caused by using waste heat is recovered by 3.42MJ. The exhaust of CO2 in the stage of incinerating itself is 1.13kg/f.u. but it gets 0.32kg/f.u. from the energy recovery, so, the total counts 0.82kg/f.u. The order of impact categories from the LCA result is global warming(77.7%), abiotic resource depletion(6.3%) and acidification, eutrophication, ecotoxicity. Even though it might somewhat reduce the bad effect on ecology to cut back the amount of carbon, which is the main ingredient in CO2, however, given that the amount of carbon in paper remains unchanged, that is not the proper plan. Now we can suppose that promote energy recovery would help minimizing the overall burden on the environment. One solution to increase the rate of energy recovery is reducing the content of water in food waste came along with waste paper. And this results in lessening the burden on the environment. Promoting the recycling rate of waste paper, which accounts 56% now, might be the basic solution to reduce the burden on ecology generated from the incineration of paper.

골격근 근형질세망의 ATPase활성도에 대한 Vanillylnonanamide의 영향

박경섭,홍장희,류영수,성지연,허강민,임종호,이재흔,석정호 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.2

To investigate the effect of vanillylnonanamide(VN) on the ATPase activity of the sarcoplasmic reticulum(SR) of the skeletal muscle, we prepared the SR vesicles from the back muscle of the rabbit, and measured ATPase activity. The results as follows: Ca-ATPase activity was about 50% in the total ATPase activity of skeletal muscular SR. In the reaction mixture with calcium, 100μM VN increased ATPase activity to 20%, and 100 nM and 10 μM thapsigargin(THP) inhibited the ATPase activity to 50% and 60%, respectively. And 100 μM VN plus 100 nM or 10 μM THP more inhibited ATPase activity than THP alone did it. However, without calcium, 100μM VN did not affect ATPase activity, and 10 μM THP inhibited it to 41%, but VN plus THP inhibited it to 31%. The above results show that VN in the reaction mixture with or without calcium has the different action to ATPase activity when it is used alone or together with Ca-ATPase inhibitor THP. This suggests that VN might increase or decrease the skeletal SR Ca-ATPase activity through affecting the lipid membrane around the Ca-ATPase.

2009년 인플루엔자 대유행 중 인플루엔자 진료소 방문자의 연령 분포 변화

김백남,곽이경,문치숙,김연숙,김의석,배인규,염준섭,이창섭,허지안 대한감염학회 2010 감염과 화학요법 Vol.42 No.2

The pandemic influenza (H1N1 2009) virus, after being introduced in Korea in April, 2009, spread rapidly nationwide in mid-2009. This study was conducted to characterize trend in age distribution of visitors to Flu-clinics during the pandemic. Demographic, clinical and laboratory data of visitors to flu clinic from Week 36 to 52 (August 30 to December 26) of 2009 were retrieved and collected from electronic databases at 9 hospitals. Visitors 0-6, 7-12, 13-18, 19-29, 30-64, and 65 years or more of age were classified into group I to VI, respectively. A total of 107,467 visitors were seen at Flu-clinics for a 17-week study period. Of those, 32,485 were laboratory-confirmed. Antivirals were prescribed for 62,533 visitors. Numbers of visits, prescriptions of antivirals, and laboratory-confirmed cases of the pandemic influenza (H1N1 2009) peaked at Week 44. A large number of visits by group II and III were followed by those of group I and V, especially around the peak. Numbers of visits by group VI were lowest in all hospitals. In some hospitals, higher number of visits lasted longer in children than in adults while vice versa in other hospitals depending on the location. In summary, the pandemic influenza (H1N1 2009) was presumed to peak in late October and involved majorly children and students in Korea. Unique age distribution of visitors to flu clinic was observed in some hospitals.

Functional markers for bacterial blight resistance gene Xa3 in rice

Hur, Yeon Jae,Jeung, Ji-Ung,Kim, Sang Yeol,Park, Hyun-Soo,Cho, Jun-Hyun,Lee, Ji Yun,Sohn, Young-Bo,Song, You Chun,Park, Dong-Soo,Lee, Choon-Woo,Sohn, Jae Geun,Nam, Min-Hee,Lee, Jong Hee Springer-Verlag 2013 Molecular breeding Vol.31 No.4

mRNA expressions of Steroid hormone receptors during the migration in the nocturnal eel. Anguilla japonica

Ji-Yeon Hyeon,Ji-Sung Moon,Jun-Hwan Byun,Akihiro Takemura,Sung-Pyo Hur 한국수산과학회 양식분과 2017 한국수산과학회 양식분과 학술대회 Vol.2017 No.5

PCR-based allele specific markers for bacterial blight resistance gene in rice.

Yeon-Jae Hur,Jong-Hee Lee,Ji-Ung Jeung,Ji-Yoon Lee,Jun-Hyun Cho,Hyun-Jin Park,You-Chun Song,Myung-Gyu Oh,Un-Sang Yeo,Choon-Woo Lee,Min-Hee Nam 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07

The use of functional markers, it is expected to make direct identification about genetic diversity at DNA level and overcome the problem of recombination /linkage. These markers can be used to identify interesting alleles in a breeding program and indirectly select for the trait, saving money, time and labor. Bacterial blight of rice caused by Xanthomonas oryzaepv. Oryzae is a destructive disease in rice production worldwide. No bactericide is effective to control the bacterial blight disease yet. Xa3, which is a gene conferring resistance to BB of the rice plant has been previously characterized by map-based cloning. We have cloned and sequenced the Xa3/xa3 gene in Korean cultivar, Hwayoung, Ilmi and Goun with gene specific primers. Our work detected polymorphisms and PCR-based allele specific SNP markers were developed. Susceptible or resistant individuals from an F2 population developed from across between Milyang244 and Ilmi, Korean germplasms and near isogenic lines carrying BB resistance genes were screened with allele specific markers. We found that the genotype completely matched their phenotype to BB using ASP-primers. These markers could be effective to marker-assisted selection for the Xa3 gene in rice breeding programs.

Fine mapping of the Grh3, Conferring Resistance to Green Rice Leafhopper (Nephotettix cincticeps Uhler) in Rice, Oryza sativa L.

Jong-Hee Lee,Yeon-Jae Hur,Do-Yeon Kwak,Jun-Hyun Cho,Yeong-Nam Yoon,Bong-Choon Lee,Ji-Yun Lee,Sang-Yeong Kim,Yeong-Bo Sohn,Un-Sang Yeo,Yu-Chun Song,Choon-Woo Lee,Min-Hee Nam,Jae-Keun Sohn 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07

The green rice leafhopper (GRH), Nephotettix cincticeps Uhler, is one of the most serious insect pests affecting cultivated rice (Oryza sativa L.) in temperate regions of East Asia. To understand the genetic basis of the GRH resistance, a F2 population derived from across between a highly resistant variety,Cheongnam and a susceptible variety, Junambyeo was analyzed by genetic analysis and association mapping. GRH resistance was evaluated using the F2 populations. The results showed that a single dominant gene in Cheongnam. DNA from 22 F2 individuals being either resistant or susceptible were pooled to produce bulk resistant and bulk susceptible DNA samples. Parents and bulks were screened with 192 SSR markers and twolinked SSRmarker, RM6082 and RM20145 were identified.Subsequent mapping in the original mapping population showed that thelocusis flanked by the SSR markers, RM20130 and RM20152 on chromosome 6. To physically map this locus, the-linked markers were landed on the artificial chromosome clones of the reference cv., Nipponbare, released by the International Rice Genome Sequencing Project. The DNA markers found to be closely linked to Grh3 would be useful for marker-assisted selection for the improvement of resistance to GRH in rice.

Molecular mapping of QTLs related to cold tolerance at seedling stage in rice

Tae Heon Kim,Yeon-Jae Hur,Saisbeul Lee,Ji-Yoon Lee,Youngbo Son,Sung Hwan Oh,Sang-Ik Han,Jun-Hyun Cho,You-Chun Song,Jong-Hee Lee,Min-Hee Nam,Dong-Soo Park,Yeong-Up Kwon,Dongjin Shin 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

Rice is a staple food crop for more than half of the world population. Severe losses of rice production was caused by various environmental conditions such as cold, heat and flooding annually. Rice is a highly sensitive to low temperature below 15-20 ℃ because of originating from tropical or subtropical climates. Especially, seedling of rice is easily damaged to low temperature and result in seedling yellowing, growth retardation, reduced tillering and yield losses at last. We used a recombinant inbreeding lines (RIL) population of 384 individuals derived from a cross between Hanareum 2, a highly cold sensitive variety and Unkwang, a cold tolerant variety for molecular mapping of QTLs related to cold tolerance. Seedling discoloration of each lines and parents caused by cold response were investigated in field condition after transplanting. And leaf samples of RIL population were collected for evaluation of chlorophyll content using 80% acetone extraction. The seedling of each lines and parents was subjected to low temperate by 5~13 ℃ during 14 days. The cold recovery score (CRS) of RILs was recorded after 4 days recovery period according to standard evaluation system (SES, IRRI). Total of eight QTLs were detected on chromosome 1, 7, 8, 10, 11 and 12 using cold tolerance traits, chlorophyll content, seedling discoloration and cold recovery score in 384 RILs. The qCRS12, which detected on chromosome 12 between two flanking markers id12002113, id12002563 (1.1 Mbp) showed 25 LOD score with 26% of phenotypic variation of cold recovery score in RILs population. The positive allele contributing to cold tolerance came from the cold tolerant parent Unkwang. The result may provide useful information for a marker-assisted breeding program to improve cold tolerant in rice.

Physiologycal process during slvering of the nocturnal eel, Anguilla japonica: plasma levels of dopamine and glucose concentrations in female Japanese eel

Ji-Sung Moon,Ji-Yeon Hyeon,Jun-Hwan Byun,Akihiro Takemura,Sung-Pyo Hur 한국수산과학회 양식분과 2017 한국수산과학회 양식분과 학술대회 Vol.2017 No.5