Fluoride, Bisphosphonate 및 Gallium이 상아질 흡수 억제에 미치는 영향

백은영,유윤정,노병덕,최윤정,이승종 大韓齒科保存學會 1997 Restorative Dentistry & Endodontics Vol.22 No.2

Replacement resorption is followed by the delayed replantation of an avulsed tooth. Currently no effective treatment is substantiated for replacement resorption. The purpose of this study was to investigate the effect of stannous fluoride, bisphosphonate(etidronate disodium) and gallium nitrate, which have been shown to reduce dentin resorption, on human dentin. Osteoclasts were collected from tibeas of chich embryo. The cells were well agitated to prevent adhesion and seeded onto the sliced human dentin wafers which had been soaked in either culture media(control), or several different concentrations of stannous fluoride, etidronate disodium(1-hydroxyethylidene-1, 1-bisphosphonate disodium), and gallium nitrate. Resorption was measured by counting the number of resorptive pit produced by the cells. Results are ad follows. Stannous fluoride and etidronate disodium showed statistically significant reduction of dentin resorption(p<0.05) but the effect of stannous fluoride seemed to be its high cytotoxicity. Etidronate disodium did not show cytotoxicities in all experimented concentrations. Gallium nitrate did not show differences in resorption either between different concentrations of from the control group.

Expansin으로 형질전환 된 담배의 생장 특성

신하정, 성현정, 백승준, 김보미, 엄유리, 조은정, 정찬문, 이이 충북대학교 연초연구소 2008 煙草硏究 Vol.21 No.-

-본문참고-

고등학생의 성, BMI에 따른 자가건강관리행태,신체적 자기효능감에 관한 연구

백영호,고정림,천은석 부산대학교 과학교육연구소 2007 교사교육연구 Vol.46 No.2

본 연구는 고등학생의 성, BMI에 따른 자가건강관리행태와 신체적 자기효능감에 관한 연구를 위해 B·U시에 있는 13개 고등학교 총 1,810명을 대상으로 설문을 실시하여 불성실한 84명을 제외한 1,726명을 대상으로 고등학생들의 성, 계열, BMI에 따른 자가건겅관리행태를 비교하였다The Journal, College of Education. Vol. 46, No. 2, (2007) 성에 따른 자가건강관리행태는 남·여학생 모두 평균수면시간은 6시간, TV시청시간은 1시간으로 컴퓨터 사용시간은 남학생 2시간·여학생 1시간으로 남·여학생 모두 스트레스해소방법은 음악듣기, 아침식사여부는 매일 먹는다, 간식횟수는 매일 먹는다, 간식선호도는 비스켓, 빵류, 인스턴트섭취횟수는 주1~2회, 선호음식은 육류, 선호음료는 주스류, 체형인지정도는 약간 살찐 체형, 운동을 하지 않는 이유는 시간이 없어서, 운동을 하는 이유는 신체적 건강을 위해서, 음주횟수는 마시지 않는다, 흡연·음주가 학업에 미치는 영향은 학업에 지장이 있는 것 같다. 신경안정제·수면제·각성제 등의 복용여부는 없다로 나타났다. TV시청시간, 아침식사여부, 선호음료, 체형인지정도, 신경안정제, 수면제, 각성제 등의 복용여부에서는 남학생이 더 나은 자가건강관리행태를 컴퓨터 사용시간, 간식선호도, 인스턴트섭취횟수, 선호음식, 음주횟수, 흡연·음주가 학업에 미치는 영향에서는 여학생이 나은 자가건강관리행태를 나타냈다. BMI에 따른 자가건강관리행태는 저체중·정상체중·과체중 모두에서 평균수면시간은 6시간, TV시청시간은 1시간으로 컴퓨터 사용시간은 1시간, 스트레스해소방법은 음악듣기, 아침식사여부는 매일 먹는다로 간식횟수는 저체중·정상체중은 매일 먹는다·과체중은 주 1~2회로 저체중·정상체중·과체중 모두에서 간식선호도는 비스켓·빵류, 인스턴트섭취횟수는 주 1~2회, 선호음식은 육류, 선호음료는 주스류로 체형인지정도는 저체중은 마른체형으로 정상·과체중은 약간 살찐 체형으로 저체중·정상체중·과체중 모두에서 운동을 하는 이유는 신체적 건강을 위해서, 운동을 하지 않는 이유는 시간이 없어서, 음주횟수는 마시지 않는다, 흡연·음주가 학업에 미치는 영향은 학업에 지장이 있는 것 같다, 신경안정제·수면제·각성제 등의 복용여부는 없다로 나타났다. 정상은 저체중·과체중보다 간식선호도에서 과체중은 정상·저제중보다 아침식사여부, 간식횟수, 선호음식, 체형인지도에서 자가건강관리행태가 좋았다. 신체적 자기효능감은 성별로는 남학생이 여학생보다 높게 나타나 유의한 차이를 나타내었고, 계열별로는 유의한 차이가 없었으며, BMI는 정상체중이 저체중과 과체중보다 높게 나타나 유의한 차이를 나타내었다. 이상의 연구결과 청소년들의 올바른 자가건강관리행태를 높이고, 잘못된 생활습관과 식습관을 바로 잡을 수 있는 체계적이고 지속적인 청소년 자가건강교육 프로그램이 개발되어야 할 것이며, 청소년기에 맞는 보다 일반화된 검사를 할 수 있는 자가건강관리행태와 신체적 자기 효능감의 설문지 개발과 자가건강관리의 능동적 실천 방안을 마련해야 된다고 본다. For the study on the type of self-care status according to gender, BMI and physical self- efficacy of high-school students, this study took a census at 1,810 students of 13 high-schools at area of U and P. This study took a Chi-square to compare the type of self-care status according to gender, BMI of high-school students. The study calculate mean, standard deviation and then perform one-way ANOVA to compare physical self-efficacy of high-school students. Verifications on those was executed by Duncan with the significance level of a=.05. The conclusions of this study are followed below. At both boy and girl students: average sleeping time -6 hours, average watching TV time - 1 hour, the methods of releasing a stress : listening to music, yes or no of eating a breakfast -Taking a breakfast everyday, how often they eat snack foods - everyday, the preferred snack foods - biscuit, bread, the frequency of eating fast-foods - 1~2 per week, the preferred foods - meats, the preferred beverage - juices, the cognition on body type - a little fat body. The reason why they don't excise - having no time to excise, the reason why they do excise - To have a healthy body, the frequency of drinking alcohol - zero, the affection of smoking and drinking alcohol on studying - It seems to be, yes of no of taking medicines such as tranquilizer, sleeping drug, stimulant - No. The time of using a computer - boys (2 hours) / girls (1 hour).Boy students have a better types of self-care status than girl students in watching TV time, yes or no of eating breakfast, the preferred beverage, cognition on the body type, yes of no of taking medicines such as tranquilizer, sleeping drug, stimulant. Girl students have a better types of self-care status than boy students in the time of using a computer, the preference of snack foods, the frequency of eating fast-foods, the preferred foods, the frequency of drinking alcohol, the affection of smokingㆍdrinking alcohol on studying. At all under, normal, over-weight students: the average sleeping time - 6 hours, the average watching TV time - 1 hour, the average time in using a computer - 1 hour, the methods of releasing a stress - listening to music, yes or no of eating a breakfast : -Taking a breakfast everyday, the preferred snack foods - biscuit, bread, the frequency of eating fast-foods - 1~2 per week, the preferred foods - meats, the preferred beverage - juices. The reason why they do exercise : -To have a healthy body, the reason why they don't excise -having no time to excise, the frequency of drinking alcohol - zero, the affection of smoking and drinking alcohol on studying - It seems to be, yes of no of taking medicines such as tranquilizer, sleeping drug, stimulant - No. The frequency of eating snack-foods : low & normal - everyday / over - 1~2 times. The normal weight students have a better types of self-care status than low or over-weight in the preferences of snack-foods. the over weight students have a better types of self-care status than the normal or low-weight in yes or no of eating a breakfast, the frequency of eating snack-foods, the preferred foods, the cognition on body type. On gender, it shows a meaningful difference that the boy students are higher than the girl students in the physical self-efficacy. On BMI, it shows a meaningful difference that normal weight are higher than low & over weight in the physical self-efficacy. These results show us that we have to develop a systematic and continuous health education programs for juveniles-self that enhance upright types of self-care status and fix the wrong living and eating habits. And these results also show us that we have to prepare the types of self-care status which can be generally tested for juveniles and the development of census on the physical self-efficacy and active practice plan on self-care status.

저온 저장 감귤에서의 MA포장의 효과

이상백,김은정,고영환,고정삼 제주대학교 공과대학 첨단기술연구소 2001 尖端技術硏究所論文集 Vol.12 No.2

The effects of MA packaging on the low temperature storage of satsuma mandarin, overwintering satsuma and Kiyomi tangor were investigated. Thickness of film, holes in film and incorporation of antimicrobial agent were considered as parameters for MA packaging. Chitosan was applied to surface of fruits to determine the effects of coation during MA storage. Thickness of film and holes in a bag did not affect decay ratios in three fruits. Decay ratio of satsuma mandarin packaged with LDPE film with 2-5% ceramic antimicrobial agent slightly decreased. Chitosan coating lowered decay ratio of fruit during MA storage. MA packaging with LDPE film was effective in lowering weight loss and preventing delamination of fruits. MA packaging did not affect qualities of fruit during storage.

대학생 흡연자의 금연경험에 따른 건강신념차이

구정일,김민정,김동희,백정희,안현실,은가희,우혜령,이명희,이수현,김수지 이화여자대학교 간호과학대학 2003 이화간호학회지 Vol.- No.37

It has been generally known that smoking is one of the worst factor increasing disease and mortality in human health since in 1950's and nowadays. But regardless of various proofs about social or economical problems due to smoking, current smoking rate has not been decreased in our country. Until now, most of tobacco use and its addiction researches have been focused on the adolescent or adult women smokers not on the university students. Therefore, the purpose of this study was to investigate smoking cessation of university smokers and analyze the health belief-perceived sensitivity, severity, benefits and barriers- difference, then to provide basic data for effective smoking cessation strategy for university smokers. The subjects were comprised of 181 university smokers from 15 universities in Seoul. The data were collected by structured questionaires. The questionaires were designed to measure general characteristics, smoking cessation and health belief, based on Ahn(2003)'s result on the Study of Smoking attitude, Behavior and Smoking Cessation of Adult Male and Lee(1987)'s result on Relationships Between the Health Belief Model and Smoking Habits. The data were collected from May 5 to 16. The collected data were analyzed by SPSS program. The actual number, percentiles, means, standard deviation, t-test and ANOVA were done. The result of this study were as follows; 1. The general characteristics of the subjects of this study The range of age was from 18 to 34 and the averaging age was 23. The subjects of this study were 141 males and 40 females. The religions were Christianity 25.4%(46), Buddhism 12.7%(23), Catholic 23.2%(42), no religion 37.0%(67). The residential forms were living with family 59.1%(107), cooking food for oneself 28.7%(52), dormitory 5.0%(9), boarding house 1.7%(3). Smoking starting age were university 43.1 %(78), high school 29.8%(54), middle school 14.9%(27), in the army 6.1 %(11), elementary school 1.1 %(2). 2. The smoking cessation of the subjects 80% of current smokers showed quitting smoking decision and 20% have not tried. The frequency of quitting smoking decision were from 1 to above 8 and mean was 3.06. As for smoking cessation plan, 54.7%(99) current smokers answered yes, 3.9%(7) said no, 35.4%(64) had no idea and 6.1 %(11) didn't answer. As for the reason of never quitting smoking decision, 71.42%(25 among total 35) have no need to quit smoking and the others said difficulty of smoking cessation. As for the main reason of smoking cessation decision, 54.7%(99) answered for the health, 7.2%(13) family advice, 15.5%(28) girl/boy friend's advice, 1.7%(3) to save money. As for the reason to fail smoking cessation, 56.7%(68) were will-lack, 17.5%(21) stress, 15%(18) smoking mood, 10%(12) withdrawl symptom. As for the smoking cessation method, 85.0%(125) were oneself-will, 2.7%(4) way acquired by mass-media, 2%(3) doctor's prescription, 2%(3) religion's help, 0.7%(1) smoking cessation school. As for the difficulty in smoking cessation, 42.2%(62) were drinking meeting, 23.1 %(34) no alternative of stress release, 12.2%(18) withdrawl symptom, 11.6%(17) having nothing to do, 7.5%(11) friend's encouragement. As for the most difficult cigarette to quit, 67.8%(99) were all-day smoking except the first smoking in the morning, 32.2%(47) the first smoking in the morning. 3. Health belief as for general characteristics Gender - The total point in benefits showed higher in male(28.5177) than female(26.6750). There was significant difference(t=.778, p<.05). The total point in health belief showed higher in male (105.8298) than female(l00.5000). So there was significant difference(t=.345, p<.05). Age - There was significant difference in benefits between age(10's-25.83, 20's-28.39, 30's-32.00)(F=3.73, p<.05). Smoking starting age - There was significant difference in total point of sensitivity and health belief(sensitivity F=4.00, p<.Ol, health belief F=2.843, p<.05). As for sensitivity, subjects who started smoking in the army showed the highest(33.36) and ones in high school showed the lowest(26.96). The total point in health belief showed the highest in elementary school(l19.00) and the lowest in high school(100.98). 4. Health belief as for smoking cessation There was significant difference in health belief as for smoking cessation(t=0.189, p=0.OO2). Sensitivity point showed higher in smoking quitting trial smokers(29.2) than non-trial smoker (26.9). Severity point showed higher in trial smokers (30.7) than non-trial smokers(28.9). Benefit point showed higher in trial smokers(28.6) than non-trial smokers(26.2). There was no significant difference in barriers point.

고교생의 자가건강관리형태에 관한 연구

고정림,천은석,백영호 釜山大學校 附設 體育科學硏究所 2008 體育科學硏究所 論文集 Vol.24 No.1

본 연구는 고등학생의 자가건강관리형태에 관한 연구를 위해 B.U시에 있는 13개 고등학교 총 900명을 대상으로 설문을 실시하여 불성실한 25명을 제외한 875명을 대상으로 고등학생들의 자가건강관리형태를 비교하였으며, 자료처리는 chi-square 검정을 실시하였으며, 유의수준은 a=.05로 설정하여, 다음과 같은 결론을 얻었다. 강관리형태는 성별에 따른 체형인지도와 운동여부의 형태를 조사한 결과는 다음과 같다. 여학생, 남학생 모두에서 체형인지도는 약간 살찐형, 운동참여이유는 건강, 운동 불참이유는 시간이 없어서로 각각 나타났으며, 여가시간 사용 형태에서 컴퓨터 사용시간은 여학생이 1시간 남학생은 안한다가 가장 높았고, 스트레스 해소 방법과 수면시간은 남녀 모두 음악 듣기와 6시간의 수면이 가장 높게 나타났다. 성별에 따른 음식 섭취형태는 선호음식이 여학생 남학생 모두 육식 위주가 가장 많았고, 선호음료는 여학생이 쥬스류, 남학생은 쥬스와 유제품이 가장 높은 것으로 나타났다.........

Efavirenz, indinavir, lopinavir, ritonavir의 LC-MS/MS를 이용한 동시 정량법

채정우,배경진,백인환,서정원,이병요,이은주,남진경,강원구,권광일 충남대학교 약학대학 의약품개발연구소 2009 藥學論文集 Vol.24 No.-

Efavirenz indinavir and kaleta (co-formulation of lopinavir and ritonavir) are important antiretroviral drugs which have been proved to be human immunodeficiency virus (HIV) protease inhibitors and reduced the morbidity and mortality associated with HIV-1 infection. A brief and fast high performance liquid chromatography coupled with electrospray mass spectrometry (LC-MS/MS, API 4000) method for the determination of 4 anti-retroviral agents (efavirenz, lopinavir, indinavir, ritonavir) in human plasma was developed and validated. A simple protein precipitation method was used on 100μl of human plasma. And internal standard solution (10 ng/ml methaqualone) 1ml and reconstitution solution (MeOH) 1ml were added. After vortexing for 30 s and centrifuging at 13,200rpm for 10min, 2μl of supernatant was injected into the column (XTerra MS C_(18) column, 2.1mm × 50mm 3.5㎛ particle size). The mobile phase consisted of MeOH and 0.1% formic acid in water (80:20 , v/v). The chromatogram was run for 1.5 min at a flow rate of 300μl/min. A triple quadrupole mass spectrometer was operated in a positive ion mode (lopinavir, indinavir, ritonavir) and negative mode (efavirenz), simultaneously and multiple reaction monitoring (MRM) was used for drug quantification. The precursor-to-product ion transitions of m/z 316→69 (efavirenz) and 629→447 (lopinavir) and 614→421 (indinavir) and 721→296 (ritonavir)were used to measure and quantify the analyte. The limit of quantitation (LOQ) was 50 ng/ml (efavirenz, indinavir, ritonavir) and 100 ng/ml (lopinavir). The weighted (l/y²) calibration curve was linear over human plasma range 50∼5000ng/ml (efavirenz), 100∼20000ng/ml (lopinavir), 50∼10000ng/ml (indinavir), 50∼2000ng/ml (ritonavir), correlation coefficient(r²) of 4 antiretroviral agents were higher than 0.998. Accuracies and intra-run precisions ranged within 86.60 and 113.29%, 1.06 and 11.16% for all 4 drugs analysed. This analytical method used to determine these drugs was fast and easy to perform, with minimal sample preparation, and without compromising precision and accuracy. The developed method was successful to determine antiretroviral agents in human plasma, and proved suitable for clinical pharmacokinetic study.

退行性關節炎 韓方治療에 對한 最近 硏究 動向 : 臨床硏究 方法論을 中心으로 Herbal Medicines in the Treatment of Osteoarthritis in Pubmed and Chinese Medical Journals

서병관,류성룡,이송실,허정은,백용현,이재동,최도영,조윤제,김남재,박동석 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Objective : The aim of this study was to review systemically clinical trials on the effectiveness and safety of herbal medicines in the treatment of osteoarthritis. Methods : Computerized literature searches were carried out on seven electronic databases, and hand-searching on some chinese medical journals in library of Kyung Hee Medical Center. Trial data were extracted in a standardized, predefined manner and assessed independently. Results : 1. Thirty reports of clinical trials and two reports of meta-analyses concerning herbal medicine were collected and reviewed Among these reports three medical herbs were applied as topical medicine and others as internal medicine. 2. The western studies established NSAIDs or placebo as their control group. Five chinese reports established formulated herb pill(Ruanshnagshenjin pill) as their control group and Six did not establish a control group at all. 3. ACR was the most highly used diagnostic criteria in the western studies while the Chinese used their official criteria established by their government or the criteria of their text books. 4. 20 reports chose the Lequesne functional index, SHAQ, WOMAC OA index, AIMS, and their own unique scoring system as the criteria of analysing the effect. Others chose clinical symptoms, articular functions, and lab finding as their criteria. 5. 7 single herbs and 19 formulated herbs were studied. Among the formulated herbs, Achyranthes japonica was studied in 10 of the studies and Angelica gigantis Radix in 8, making them the most often studied herbs among the studies.

Intensity Change of Tropical Cyclones over the Western North Pacific with Respect to the RSMC-JTWC Comparison

Eun-Hee Baek,H. Joe Kwon,Yun-Je Lee,Seung-Hoon Lee,Chan-Soo Kim,Eun-Jeong Cha 건국대학교 기후연구소 2011 기후연구 Vol.6 No.1

This paper reexamines the interannual intensity change of tropical cyclone (TC) over the western North Pacific. Analyses are done for the annual extreme intensity and the average intensity of the five strongest typhoons based on the best track data issued from the RSMC (Regional Specialized Meteorological Center) Tokyo and the JTWC (Joint Typhoon Warning Center). Trends over the last 30+ years in one data set are nearly opposite in another. Specifically, the TC intensity tends to increase with the years in the JTWC data, whereas the opposite is found in the RSMC data. Realizing that one data set shows a significant statistical difference from the other, a homogenization process has been applied to the original data so that comparisons of the two data sets and the trend analyses become more meaningful than those with solely the original data. With the homogenized data, we present some cautious conclusions regarding the TC intensity changes over the western North Pacific. The annual extreme TC intensity has been decreasing, while the strong TCs have become stronger over the years. For TCs entering the KMA emergency area and directly hitting Korea, we are hesitant to make any conclusions because the corresponding area is small so that the number of TCs entering the area each year is too small to have any statistically significant implications.

Effects of the electrical parameters and gas flow rate on the generation of reactive species in liquids exposed to atmospheric pressure plasma jets

Baek, Eun Jeong,Joh, Hea Min,Kim, Sun Ja,Chung, T. H. American Institute of Physics 2016 Physics of plasmas Vol.23 No.7