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- 저자 : ( In Tak Chu ) (검색결과 62 건)
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The Incidences and Locations of Osteochondral Lesions of the Talus in Ankle Fracture
In-Tak Chu(주인탁),Yang-Soo Kim(김양수),Soung-Ho Yoo(유성호),In-Soo Oh(오인수) 대한정형외과학회 2004 대한정형외과학회지 Vol.39 No.5
목적: 족근관절 골절에서 발생하는 거골의 골연골병변은 외상성 관절염을 속발할 수 있으므로 적절한 치료가 필요하다. 족근관절 골절시 거골의 골연골병변의 빈도가 높다고 알려져 있으나 골절의 관혈적 정복시 사용하는 수술적 도달법으로는 거골의 골연골병변의 유무를 확인하기가 어려워 이에 대한 치료가 지연될 수 있다. 저자들은 족근관절 골절시 발생하는 거골의 골연골병변의 빈도와 위치를 알아보기 위하여 수술 전 검사한 자기공명영상을 후향적으로 분석하였다. 대상 및 방법: 족근관절 골절 환자 40명의 자기공명영상을 분석하였다. 골연골병변의 위치는 9구획으로 분류하였는데 거골 체부 관절면을 전후 그리고 내외측으로 3등분하여 내측, 중심부, 외측, 그리고 전방부, 중심부, 후방부로 나누어 각 부위의 발생 빈도를 조사하였다. 손상기전은 회외기전, 회내기전으로 나누었다. 결과: 족근관절 골절 40명의 환자 중 28명의 환자(70%)가 거골의 골연골병변이 있었고, 13명의 환자(46%)가 회외기전에 의해, 15명의 환자(54%)가 회내기전에 의해 발생하였다. 회외기전 손상군에서 7명은 외측부에, 1명은 중심부에, 5명은 내측부에 발생하였고, 8명은 후방부에, 3명은 중심부에, 2명은 전방부에 발생하였다. 회내기전 손상군에서는 13명은 외측부에, 1명은 중심부에, 1명은 내측부에 발생하였고, 9명은 후방부에 5명은 중심부에 1명은 전방부에 발생하였다. 외상 후 거골의 골연골병변의 빈도는 통계적으로 회내, 회외기전 손상군에서 모두 외측과 후방에 높은 발병률을 보였다. 결론: 족근관절 골절에서 발생하는 거골의 골연골병변의 조기 진단을 위하여 족근관절 골절 치료시 거골의 후방 혹은 외측부의 정밀한 관찰이 요구되며, 이에 대한 추가적인 치료가 필요하다. Purpose: An osteochondral lesion of the talus in ankle fracture needs appropriate treatment to prevent traumatic arthritis. Despite the high incidence of an osteochondral lesion in cases of ankle fracture, it is difficult to identify the location of the lesion during open fracture reduction due to limitation of the surgical approach. Therefore, we reviewed retrospectively the MRIs of ankle fractures to determine the incidences and locations of osteochondral lesions of the talus according to ankle fracture injury mechanism. Materials and Methods: The MRIs of forty patients with ankle fractures were reviewed. Locations of osteochondral lesions were divided into nine areas; i.e., medial, central, lateral and anterior, central, posterior. Injury mechanisms were divided into supination and pronation groups. Results: Twenty eight (70%) out of 40 patients with ankle fractures had an osteochondral lesion of the talus. Thirteen (46%) patients were allocated to the supination group and 15 (54%) to the pronation group. Lesion locations were; 7 cases of lateral, 1 central, 5 medial and 8 posterior, 3 central, and 2 anterior for supination injury. In cases of pronation injury, 13 were lateral, 1 each central and medial, and 9 posterior, 5 central, and 1 anterior. The incidences of osteochondral lesions were significantly different at the lateral and central areas, and also between the posterior and anterior areas in both the supination and pronation groups. Conclusion: For osteochondral lesion in cases of ankle fracture, careful observation of the posterior and lateral areas of the talar dome should be performed and additional treatment should be added for the lesion if required.
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John Man Tak Chu,Wei Xiong,Ke Gang Linghu,Yan Liu,Yan Zhang,Guan Ding Zhao,Michael G. Irwin,Gordon Tin Chun Wong,Hua Yu 한국뇌신경과학회 2018 Experimental Neurobiology Vol.27 No.6
A proportion of patients experience acute or even prolonged cognitive impairment after surgery, a condition known as postoperative cognitive dysfunction (POCD). It is characterized by impairment in different cognitive domains and neuroinflammation has been implicated as one of the inciting factors as strategies targeting inflammation tend to improve cognitive performance. Siegesbeckia Orientails L. (S. Orientails) is a common Chinese medicinal herb used for managing chronic inflammatory diseases. We investigated if pretreatment with S. Orientails before surgery confers any neuroprotective effects in postoperative animals in terms of reducing inflammation and mitigating cognitive impairment. Three-month-old male C57BL/6N mice were fed different doses of S. Orientails extract for 14 days before they underwent a laparotomy. After cognitive testing they were sacrificed on postoperative day (POD) 3. Our results showed that animals with extract pretreatment demonstrated memory improvement in a dose-dependent manner compared with control. Further, evidence for the attenuation of systemic and neuroinflammation was found in the pretreated animals, along with the inhibition of inflammatory pathways and significantly reduced tau phosphorylation in the hippocampus. Taken together, these results demonstrated a neuroprotective effect of S. Orientails in postoperative animals, indicating a therapeutic potential of S. Orientails in minimizing POCD and the possibility of utilizing this traditional Chinese medicine perioperatively.
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LPCD법에 의한 Tin박막의 전계 에미터 어레이 제작
조경제,이상윤,류정탁,김연보,이진호 大邱大學校 科學技術硏究所 2001 科學技術硏究 Vol.8 No.2
Using low pressure chemical vapor deposition (LPCVD), TiN thin films as field emitter array were fabricated. In this Work, a method was transfered to a substrate and the wet-etching of the silicon substrate instead of fabricated method of mold shape was using in generally but we have fabricated gated field emitter tips as using mold shape of the new method that using a side wall space structure. Following sequences such as LPCVD method of a gate electrod and gate oxide on a silicon substrate and defesited BPSG thin film as a high temperature was flowed by the mold shape of a sharpen, the TiN as a materials of emitter tips was deposited after was bounded by anodic bonding and the wet-etching of the silicon substrate by using KOII solution, the last have fabricated a gated field emitter arrays of a sharpen. These emitters were estmated by scanning electron microscopy and X-ray diffraction.
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TAK, EUNYOUNG,HWANG, SHIN,LEE, HAN CHU,KO, GI-YOUNG,AHN, CHUL-SOO,YOON, YOUNG-IN,LIM, YOUNG-SUK,JUN, DAE-YOUNG,KIM, KI-HUN,SONG, GI-WON,MOON, DEOG-BOK,RYOO, BAEK-YEOL,KIM, NAYOUNG,LEE, SUNG-GYU Potamitis Press 2016 Anticancer research Vol.36 No.11
<P>Background/Aim: We investigated the expression of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) and HBV X protein (HBx) in human hepatocellular carcinoma (HCC) and evaluated the effect of high-concentration nucleos(t)ide analogs (NUCs) on liver tumor cell lines. Materials and Methods: This study consisted of three parts: part I used human blood and non-tumor liver tissues; part II used human HCC and adjacent liver tissues; and part III used an HBV-expressing liver tumor cell line. Results: There were close correlations among blood and liver HBV DNA and liver cccDNA. HBV cccDNA and HBx were highly up-regulated in HCC compared to adjacent liver tissues despite NUC therapy. HBV cccDNA and HBx were highly up-regulated in the cccDNA-expressing HepG2.2.15 cell line. Their expression was down-regulated and apoptosis was induced by a very high concentration of NUCs in dose-and time-dependent manner. Conclusion: Very high concentrations of NUCs may have a novel potential to kill replicating HBV-expressing liver tumor cells.</P>
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주인탁,유경호 대한골절학회 1997 대한골절학회지 Vol.10 No.1
Isolated dislocation of the tarsal navicular is very rare and its mechanism of injury and treatment is not well established, In our case, the naricular is dislocated plantomedially resulting from hyperplantar flexion, abduction injury with longitudial axial load. Open reduction and internal fixation was required because of pulling by tibialis posterior tendon. There was no traumatic arthritis at talo-navicular joint and naviculo-cuneiform joint and no evidence of avascular necrosis of the tarsal navicular at postoperative 15months follow-up.
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윤성탁,주용하 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.4
경기도 북부지방의 환경조건에 적응하는 콩 품종을 선발하고자 13개 품종을 공시하여 생육 및 수량특성을 조사ㆍ검토한 결과는 다음과 같다. 1. 성숙기에 13개 품종의 경장은 74.4~134.9㎝의 분포를 보였으며, 가장 경장이 큰 품종은 송학콩으로 134.9㎝이었으며, 가장 작은품종은 대황콩으로 74.4㎝이었다. 2. 주당협수는 47.1~62.4개의 분포를 보였으며, 협수가 가장 많은 품종은 장수콩으로 62.4개이었으며, 가장 적은 품종은 대황콩으로 47.1개이었다. 3. 협당립수는 신팔당콩2호가 2.73개로 가장 많았으며, 그 다음은 송학콩 및 대황콩으로 각각 2.3, 2.2개이었다. 4. 등숙률은 소담콩, 황금콩, 장수콩이 각각 91.1, 90.7, 90.3%순으로 높았다. 100립중은 13개 품종이 20.8~38.2g의 분포를 보였으며, 대황콩이 38.2g으로 가장 컸다. 5. 종실수량은 신팔달콩2호가 272.6㎏/10a으로 가장 높았으며, 다음은 장원콩(255.7㎏/10a), 태광콩(250.9㎏/10a), 송학콩(249.3㎏/10a) 순이었으나, 이들간에 유의한 통계적 차이는 나타나지 않았다. 6. 13개 품종에 대한 병충해 발생정도를 보면 자반병에 이병율이 적은 품종으 장엽콩, 장수콩, 장미콩, 소담콩, 대황콩이 0.11%로 적었으며, 미이라병은 신팔달콩2호, 장미콩이 SMV 감염율은 신팔달콩 2호, 태광콩이 이병률이 적었다. 7. 수량은 주당협수, 주당립수, 주당립중과 정의 상관관계를 보여 주당협수, 주당립수, 중당립중이 많을수록 수량이 많음을 알 수 있었다. 8. 결론적으로 본시험의 결과를 종합해 보면 공시된 13개 품종 중 수량 면에서 보면 신팔달콩 2호가 272.6㎏/10a로 가장 많았으며, 병충해도 비교적 적고, 경장도 크지 않아 도복저항성도 클 것으로 판단되어 경기북부지역에서 재배하기에 적합한 품종으로 판단되었다. This experiments were carried out to evaluate the growth and yield characteristics of 13 soybean varieties and select the optimum varieties for Gyeonggi northern areas. Stem length of 13 varieties ranged from 74.4㎝ to 34.9㎝. The highest stem length was shown in Songhakkong with 134.9㎝ and the lowest was shown in Daehwangkong with 74.7㎝. Number of pods per plant of 13 varieties ranged from 47.1 to 42.4. The highest number of pods per plant was seen in Jangsukong with 62.4 and the lowest was seen by Daehwangkong with 47.1. Shinpaldalkong #2 showed the highest seeds per pod, and the next was in oredr of Songhakkong and Dashwangkong with 2.3 and 2.2 seeds, respectively. Sodamkong, Hwangkeumkong and Jangsukong showed higher ripened seed ratio by 91.1, 90.7, and 90.3% respectively among 13 varieties. One hundred seed weight ranged from 20.8 to 38.2g, and Daehwangkong showed the highest one hundred seed weight by 38.2g. Shinpaldalkong #2 showed the highest seed yield by 272.6㎏/10a, and next was in order of Jangwonkong, Taekwangkong and Songhakkong by 255.7㎏/10a, 250.9㎏/10a and 249.3㎏/10a, respectively. Purpura infection rate was the lowest in Jangyeobkong, Jangsukong, Jangmikong, Sodamkong, Daehwangkong, and Shinpaldalkong #2, Jangmikong were the lowest phomopsis seed decay caused by phomopsis spp. Low infection of SMV(Soybean Mosaic Virus) were observed in Shinpaldalkong #2, Taekwangkong. Seed yield showed positive coefficients with pods per plant, seeds per plant and seed wight per plant, showing that it is profitable to increase these characteristics for improving seed yield. In conclusion, the optimum soybean variety at Gyeonggi northern area was thought to be Shinpaldalkong #2, because it showed the highest seed yield and low damage by plant disease and insect.
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